COVID-19 vaccination perspectives among patients with Long COVID: A qualitative study.

IF 4.1 4区 医学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Human Vaccines & Immunotherapeutics Pub Date : 2024-12-31 Epub Date: 2024-03-26 DOI:10.1080/21645515.2024.2327663
Sarah R MacEwan, Saurabh Rahurkar, Willi L Tarver, Alice A Gaughan, Laura J Rush, Andrew Schamess, Ann Scheck McAlearney
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Abstract

Individuals who have Long COVID may have unique perspectives about COVID-19 vaccination due to the significant impact that COVID-19 has had on their lives. However, little is known about the specific vaccination perspectives among this patient population. The goal of our study was to improve our understanding of perspectives about COVID-19 vaccines among individuals with Long COVID. Interviews were conducted with patients receiving care at a post-COVID recovery clinic. Deductive thematic analysis was used to characterize participant perspectives according to the vaccine acceptance continuum framework, which recognizes a spectrum from vaccine acceptance to refusal. From interviews with 21 patients, we identified perspectives across the continuum of vaccine acceptance. These perspectives included acceptance of vaccines to prevent future illness, concerns about vaccine side effects on Long COVID symptoms, and refusal of vaccines due to perceived natural immunity. A limitation of our study is that these perspectives are specific to individuals receiving care at one post-COVID recovery clinic. In conclusion, our study demonstrates that some patients with Long COVID are uncertain about COVID-19 vaccines and boosters but may also be amenable to conversations that impact future vaccination acceptance. Patient perspectives should be considered when communicating recommendations for COVID-19 vaccinations to this population.

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长COVID患者对COVID-19疫苗接种的看法:一项定性研究。
由于 COVID-19 对他们的生活产生了重大影响,长效 COVID 患者可能对 COVID-19 疫苗接种有独特的看法。然而,人们对这一患者群体的具体疫苗接种观点知之甚少。我们的研究旨在加深我们对长COVID-19患者接种COVID-19疫苗的看法的了解。我们对在 COVID 后康复诊所接受治疗的患者进行了访谈。我们采用演绎主题分析法,根据疫苗接受连续体框架来描述参与者的观点。通过对 21 名患者的访谈,我们确定了疫苗接受连续体的观点。这些观点包括接受疫苗以预防未来的疾病、担心疫苗对长COVID症状的副作用,以及因认为疫苗具有天然免疫功能而拒绝接受疫苗。我们研究的局限性在于,这些观点仅针对在一家后 COVID 恢复诊所接受治疗的个人。总之,我们的研究表明,一些长COVID患者对COVID-19疫苗和强化剂并不确定,但也可能愿意接受影响未来疫苗接种接受度的谈话。在向这类人群传达 COVID-19 疫苗接种建议时,应考虑患者的观点。
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来源期刊
Human Vaccines & Immunotherapeutics
Human Vaccines & Immunotherapeutics BIOTECHNOLOGY & APPLIED MICROBIOLOGY-IMMUNOLOGY
CiteScore
7.90
自引率
8.30%
发文量
489
审稿时长
3-6 weeks
期刊介绍: (formerly Human Vaccines; issn 1554-8619) Vaccine research and development is extending its reach beyond the prevention of bacterial or viral diseases. There are experimental vaccines for immunotherapeutic purposes and for applications outside of infectious diseases, in diverse fields such as cancer, autoimmunity, allergy, Alzheimer’s and addiction. Many of these vaccines and immunotherapeutics should become available in the next two decades, with consequent benefit for human health. Continued advancement in this field will benefit from a forum that can (A) help to promote interest by keeping investigators updated, and (B) enable an exchange of ideas regarding the latest progress in the many topics pertaining to vaccines and immunotherapeutics. Human Vaccines & Immunotherapeutics provides such a forum. It is published monthly in a format that is accessible to a wide international audience in the academic, industrial and public sectors.
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