[Age-related and stress-induced changes in serotonin levels and lung monoamine oxidase activity in the experiment.]

Abstract

Study reveals age-related differences in lung metabolism parameters under stress, they are manifested in an increase in the activity of lung monoamine oxidase with a simultaneous decrease in the content of serotonin in the lungs in adult and old rats and an increase in the level of serotonin in young animals. Experiments have shown a significant age-related increase in the level of serotonin in the lungs in normal conditions and a pronounced decrease in the activity of lung monoamine oxidase only at a late stage of ontogenesis. A high negative correlation between the level of serotonin in the lung tissue and blood under stress is typical only for old animals. The severity and direction of changes in indicators are determined by age.