ASSESSMENT OF THE INCIDENCE OF MALIGNANT NEOPLASMS IN RESIDENTS OF THE MOST RADIONUCLIDE-CONTAMINATED TERRITORIES OF UKRAINE, TAKING INTO ACCOUNT THE INFLUENCE OF FORCE MAJEURE CIRCUMSTANCES.

Abstract

Objective: to determine the incidence rates of malignant neoplasms (MNs) among residents of the most radionuclidecontaminated territories (RCT) with an assessment of the possible impact of force majeure circumstanceson the specified levels of indicatorsMaterials and methods. The object of the study was residents of the RCT of Zhytomyr and Kyiv regions, the totalnumber of which decreased from 173,198 persons in 2020 to 161,978 persons in 2023. The number of residentsof the most RCT by age group in 2021-2023 was determined in accordance with the structure observed in 2020.To estimate the number of cases of MNs diagnosed in residents of the RCT, the database of the National CancerRegistry of Ukraine (NCRU) was used. To eliminate the influence of force majeure circumstances on the assessment of the incidence rate of MNs among RCT residents in 2020-2023, the regression analysis method was substantiated and applied.

Results and conclusions: The obtained data provide grounds for concluding that the previous trends towards anincrease in the frequency of MNs and certain of their nosological forms, which are considered radiationassociated (MNs of lymphoid and hematopoietic tissue, thyroid cancer, breast cancer), will persist in 2020-2023, as wellas the need to take into account the likely impact of force majeure circumstances on the magnitude of the indicators.