Pub Date : 2018-09-28DOI: 10.18499/2070-478x-2018-11-3-230
A. Andreev, A. Ostroushko
In 1883 in Georgia in a peasant family was born Justin Ivlianovich Janelidze. After graduating from the Kutaisi classical gymnasium (1903) studied in Kharkiv (1903-1905) and Geneva universities (1905 – 1909). Defended his thesis on the topic: "the question of teratoma and testicular tumors" (1909). In 1910 I. I. Dzhanelidze returned to Russia and received the title of doctor with honors, doctor of medicine (1911). From 1911 to 1914 he worked at the St. Petersburg women's medical Institute at the Department of hospital surgery. In 1911 G. I. Janelidze made a successful operation a patient with a wound of the right ventricle of the heart, in 1913 - world's first stitched the wound of the ascending aorta. During the first world war Justin Ivlianovich was a doctor of the field hospital trains. On his return from the army he worked as an assistant Professor, Department of General surgery (1921) the Petrograd medical Institute. In 1927, I. I. Janelidze was elected to the chair of hospital surgery of I Leningrad medical Institute, headed until 1943 1932 he is also scientific Director of the Leningrad Institute of emergency care. In 1939, Justin Ivlianovich - chief surgeon of the Navy of the USSR. In 1943, I. I. Janelidze was appointed chief of the Department of hospital surgery educated in the naval medical Academy. I. Janelidze is the author of over 100 scientific works, including monographs: "the Wounds of the heart and their surgical treatment", "Free skin grafting in Russia and the Soviet Union," "Bronchial fistula gunshot origin." He developed methods of surgical treatment of wounds of the heart, mediastinum, arterial and arteriovenous aneurysms of the carotid, subclavian and femoral arteries, plastic surgery, methods of reduction of dislocated shoulder and hip. Most famous was his monograph "Bronchial fistula gunshot origin", for which he was awarded the State prize of the USSR (1948). In 1946 he was elected Chairman of the all-Union society of surgeons and remained in this post until the end of life. He was editor-in-chief of the journal "Bulletin of surgery" (1937-1941 gg.), the editor of "war surgery" in the "Encyclopedic dictionary of military medicine", member of the editorial Board and the author of several chapters of the multivolume work "the Experience of Soviet medicine in great Patriotic war 1941-1945", magazines "Surgery" and "New surgical archive". I. I. Janelidze was elected Deputy of the Leningrad city Council of people's deputies. He was awarded two orders of Lenin, order of the red banner, the Gold medal "hammer and Sickle" and many medals. January 14, 1950 I. I. Janelidze died.
1883年，在格鲁吉亚的一个农民家庭里，贾斯汀·伊夫里亚诺维奇·詹内利泽出生了。从库塔伊西古典体育馆毕业后(1903年)在哈尔科夫(1903-1905年)和日内瓦大学(1905 - 1909年)学习。为他的论文题目辩护:“畸胎瘤和睾丸肿瘤的问题”(1909年)。1910年，吉赞涅列泽返回俄罗斯，获得荣誉博士头衔，医学博士(1911年)。从1911年到1914年，他在圣彼得堡妇女医学研究所医院外科部门工作。1911年，g.i. Janelidze为右心室受伤的病人做了一次成功的手术，1913年，世界上第一次缝合了升主动脉的伤口。第一次世界大战期间，贾斯汀·伊万诺维奇是野战医院火车的一名医生。从军队回来后，他在彼得格勒医学院普通外科学系担任助理教授(1921年)。1927年，I. I. Janelidze被选为列宁格勒医学研究所医院外科主席，直到1943年，1932年，他还是列宁格勒急救研究所的科学主任。1939年，苏联海军首席外科医生贾斯汀·伊夫里亚诺维奇。1943年，I. I. Janelidze被任命为在海军医学院接受教育的医院外科主任。Janelidze是100多部科学著作的作者，其中包括专著:《心脏伤口及其外科治疗》，《俄罗斯和苏联的游离皮肤移植》，《支气管瘘枪击起源》。他发明了心脏、纵隔伤口的外科治疗方法，颈动脉、锁骨下动脉和股动脉的动脉和动静脉动脉瘤的外科治疗方法，整形外科，肩关节脱位复位方法。最著名的是他的专著“支气管瘘管枪击起源”，他被授予苏联国家奖(1948年)。1946年，他被选为全联盟外科医生协会主席，并一直担任这个职位直到生命的尽头。他是《外科学公报》的总编辑(1937-1941年)，《军事医学百科辞典》“战争外科学”的编辑，《1941-1945年卫国战争中的苏联医学经验》的编委会成员和多卷本著作《外科学》和《新外科档案》的几个章节的作者。Janelidze被选为列宁格勒市人民代表委员会的代表。他被授予列宁勋章两枚，红旗勋章，“镰刀锤”金质奖章和许多奖章。1950年1月14日，I. I. Janelidze去世。
{"title":"Justin Ivlianovich JANELIDZE – Chairman of the all-Union society of surgeons, Chief surgeon of the Soviet Navy, chief editor of the journal \"Bulletin of surgery\" (135th anniversary of birth)","authors":"A. Andreev, A. Ostroushko","doi":"10.18499/2070-478x-2018-11-3-230","DOIUrl":"https://doi.org/10.18499/2070-478x-2018-11-3-230","url":null,"abstract":"In 1883 in Georgia in a peasant family was born Justin Ivlianovich Janelidze. After graduating from the Kutaisi classical gymnasium (1903) studied in Kharkiv (1903-1905) and Geneva universities (1905 – 1909). Defended his thesis on the topic: \"the question of teratoma and testicular tumors\" (1909). In 1910 I. I. Dzhanelidze returned to Russia and received the title of doctor with honors, doctor of medicine (1911). From 1911 to 1914 he worked at the St. Petersburg women's medical Institute at the Department of hospital surgery. In 1911 G. I. Janelidze made a successful operation a patient with a wound of the right ventricle of the heart, in 1913 - world's first stitched the wound of the ascending aorta. During the first world war Justin Ivlianovich was a doctor of the field hospital trains. On his return from the army he worked as an assistant Professor, Department of General surgery (1921) the Petrograd medical Institute. In 1927, I. I. Janelidze was elected to the chair of hospital surgery of I Leningrad medical Institute, headed until 1943 1932 he is also scientific Director of the Leningrad Institute of emergency care. In 1939, Justin Ivlianovich - chief surgeon of the Navy of the USSR. In 1943, I. I. Janelidze was appointed chief of the Department of hospital surgery educated in the naval medical Academy. \u0000 \u0000I. Janelidze is the author of over 100 scientific works, including monographs: \"the Wounds of the heart and their surgical treatment\", \"Free skin grafting in Russia and the Soviet Union,\" \"Bronchial fistula gunshot origin.\" He developed methods of surgical treatment of wounds of the heart, mediastinum, arterial and arteriovenous aneurysms of the carotid, subclavian and femoral arteries, plastic surgery, methods of reduction of dislocated shoulder and hip. \u0000 \u0000Most famous was his monograph \"Bronchial fistula gunshot origin\", for which he was awarded the State prize of the USSR (1948). In 1946 he was elected Chairman of the all-Union society of surgeons and remained in this post until the end of life. He was editor-in-chief of the journal \"Bulletin of surgery\" (1937-1941 gg.), the editor of \"war surgery\" in the \"Encyclopedic dictionary of military medicine\", member of the editorial Board and the author of several chapters of the multivolume work \"the Experience of Soviet medicine in great Patriotic war 1941-1945\", magazines \"Surgery\" and \"New surgical archive\". I. I. Janelidze was elected Deputy of the Leningrad city Council of people's deputies. He was awarded two orders of Lenin, order of the red banner, the Gold medal \"hammer and Sickle\" and many medals. January 14, 1950 I. I. Janelidze died.","PeriodicalId":283981,"journal":{"name":"Vestnik of Experimental and Clinical Surgery","volume":"354 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115930561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-28DOI: 10.18499/2070-478x-2018-11-3-161-166
R. Railianu, A. Botezatu, G. I. Podoliniy, Y. Paskalov
Relevance. Despite advances in the treatment of inguinal hernias are still being discussed, the issues of post-operative wound complications and disease recurrence. The inclusion in the list of risk factors for complicated postoperative course of systemic connective tissue dysplasia will allow a new look at the mechanisms of herniation in the groin area and develop morphologically adapted methods of surgical treatment. Objective. Study the characteristics of connective tissue dysmorphogenesis at hernia protrusions in the inguinal region. Results. In the main group absolutely reliable connection with all possible variants of hernia disease in the inguinal region possessed 6 (12 %) the morphological predictors, namely: dystonia dysfunction, curvature of the spine, hallus valgus, hypermobility joints, varicose disease of the lower limb and hemorrhoids. The curvature of a backbone and hyper mobility of joints occurred among manifestations of a dismorfizm at patients of control group. The area of electromyograms at reduction of muscles forming the torn down hernia the inguinal interval, on 20 % inferior area electromyograms reduction of similar muscles on contralateral from inguinal hernia to the side and on 61,4 % of area electromyograms contraction of the groin muscles of the control group patients. In a smaller proportion, but with similar characteristics reduced groups of lateral muscles, which is considered by us as local functional predictors of the implementation of systemic connective dysplasia in the hernia disease of the inguinal region. The density of the collagen fibers in the dermis of patients with inguinal hernias was 75.6 + 1.9%, which is 12,3 % lower than the result of such collagen metrics index of patients of the control group. Intensity of coloring of micropreparations of dermis of patients of control group was at the level of 36,33 + 2,1, that on 1,8 times less than this index in patients of the basic group. Conclusions. Thus, results of histology confirm reliability of the revealed morphological and local functional prerequisites of formation of inguinal hernias at connective dysplasia.
{"title":"The Role of System connective tissue dysplasia in the Formation of hernia Inguinal Area","authors":"R. Railianu, A. Botezatu, G. I. Podoliniy, Y. Paskalov","doi":"10.18499/2070-478x-2018-11-3-161-166","DOIUrl":"https://doi.org/10.18499/2070-478x-2018-11-3-161-166","url":null,"abstract":"Relevance. Despite advances in the treatment of inguinal hernias are still being discussed, the issues of post-operative wound complications and disease recurrence. The inclusion in the list of risk factors for complicated postoperative course of systemic connective tissue dysplasia will allow a new look at the mechanisms of herniation in the groin area and develop morphologically adapted methods of surgical treatment. \u0000Objective. Study the characteristics of connective tissue dysmorphogenesis at hernia protrusions in the inguinal region. \u0000Results. In the main group absolutely reliable connection with all possible variants of hernia disease in the inguinal region possessed 6 (12 %) the morphological predictors, namely: dystonia dysfunction, curvature of the spine, hallus valgus, hypermobility joints, varicose disease of the lower limb and hemorrhoids. The curvature of a backbone and hyper mobility of joints occurred among manifestations of a dismorfizm at patients of control group. \u0000The area of electromyograms at reduction of muscles forming the torn down hernia the inguinal interval, on 20 % inferior area electromyograms reduction of similar muscles on contralateral from inguinal hernia to the side and on 61,4 % of area electromyograms contraction of the groin muscles of the control group patients. In a smaller proportion, but with similar characteristics reduced groups of lateral muscles, which is considered by us as local functional predictors of the implementation of systemic connective dysplasia in the hernia disease of the inguinal region. \u0000The density of the collagen fibers in the dermis of patients with inguinal hernias was 75.6 + 1.9%, which is 12,3 % lower than the result of such collagen metrics index of patients of the control group. Intensity of coloring of micropreparations of dermis of patients of control group was at the level of 36,33 + 2,1, that on 1,8 times less than this index in patients of the basic group. \u0000Conclusions. Thus, results of histology confirm reliability of the revealed morphological and local functional prerequisites of formation of inguinal hernias at connective dysplasia.","PeriodicalId":283981,"journal":{"name":"Vestnik of Experimental and Clinical Surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125536164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-28DOI: 10.18499/2070-478X-2018-11-3-167-172
V. N. Ektov, O. E. Minakov, V. A. Muzalkov, Anna Viktorovna Kuzina, N. V. Chernyshova, Vitalii Konstantinovich Donchenko, S. G. Brezhnev
Relevance. Improvement of medical and diagnostic care for ulcerous gastroduodenal bleeding is a complex problem of modern medicine, the solution of which is connected both with the search for and introduction of modern medical technologies into clinical practice, and with the necessity to conduct in-depth analysis of the effectiveness of medical care in this pathology at various stages of its delivery. Purpose .To study the dynamics of the main indicators of the provision of medical and diagnostic care to patients with ulcerative gastroduodenal bleeding in a large multidisciplinary hospital and to evaluate the long-term results of conservative treatment of this group of patients. Materials and methods. An assessment of the dynamics of the main indicators of the provision of medical and diagnostic care for ulcerative gastrointestinal bleeding in the Voronezh Regional Clinical Hospital for the period from 1989 to 2010, during which 1831 patients were hospitalized. Long-term results of 106 patients were analyzed. Among the patients, males predominated (70.7%), the average age was 50.2 ± 4.7 years (median - 18 - 79 years). In 62 patients (58.5%) bleeding ulcer was located in the duodenum. Results. During the analyzed period there was a general tendency to reduce the number of hospitalizations by 57.8%. Surgical activity in this pathology in 1989-1993 was 56.0%; in the period from 2009 to 2013, this indicator decreased to 33.8% against the background of an increase in the postoperative mortality to 8.7%. In the evaluation of long-term results, favorable outcomes of treatment were noted - in 74.5% of patients. In 17.9% of patients with peptic ulcer with predominant localization of ulcers in the DPC, the development of various complications and recurrences of bleeding was noted, which gives grounds for recommending in the current situation the implementation of planned surgical interventions. Conclusions. Conservative treatment of ulcerative gastroduodenal bleedings with the use of endoscopic technologies creates conditions for optimization of immediate and long-term outcomes of treatment. The polyethiologic nature of the disease and the significant specific gravity of severe combined pathology makes it urgent to introduce a multidisciplinary brigade principle for the treatment of ulcerative gastroduodenal bleeding. Key words: ulcerative gastroduodenal bleeding.
{"title":"Evaluation of the dynamics of the main indicators of treatment care and the long-term results of conservative treatment of ulcerative gastroduodenal bleeding","authors":"V. N. Ektov, O. E. Minakov, V. A. Muzalkov, Anna Viktorovna Kuzina, N. V. Chernyshova, Vitalii Konstantinovich Donchenko, S. G. Brezhnev","doi":"10.18499/2070-478X-2018-11-3-167-172","DOIUrl":"https://doi.org/10.18499/2070-478X-2018-11-3-167-172","url":null,"abstract":" \u0000Relevance. Improvement of medical and diagnostic care for ulcerous gastroduodenal bleeding is a complex problem of modern medicine, the solution of which is connected both with the search for and introduction of modern medical technologies into clinical practice, and with the necessity to conduct in-depth analysis of the effectiveness of medical care in this pathology at various stages of its delivery. \u0000Purpose .To study the dynamics of the main indicators of the provision of medical and diagnostic care to patients with ulcerative gastroduodenal bleeding in a large multidisciplinary hospital and to evaluate the long-term results of conservative treatment of this group of patients. \u0000Materials and methods. An assessment of the dynamics of the main indicators of the provision of medical and diagnostic care for ulcerative gastrointestinal bleeding in the Voronezh Regional Clinical Hospital for the period from 1989 to 2010, during which 1831 patients were hospitalized. Long-term results of 106 patients were analyzed. Among the patients, males predominated (70.7%), the average age was 50.2 ± 4.7 years (median - 18 - 79 years). In 62 patients (58.5%) bleeding ulcer was located in the duodenum. \u0000Results. During the analyzed period there was a general tendency to reduce the number of hospitalizations by 57.8%. Surgical activity in this pathology in 1989-1993 was 56.0%; in the period from 2009 to 2013, this indicator decreased to 33.8% against the background of an increase in the postoperative mortality to 8.7%. In the evaluation of long-term results, favorable outcomes of treatment were noted - in 74.5% of patients. In 17.9% of patients with peptic ulcer with predominant localization of ulcers in the DPC, the development of various complications and recurrences of bleeding was noted, which gives grounds for recommending in the current situation the implementation of planned surgical interventions. \u0000Conclusions. Conservative treatment of ulcerative gastroduodenal bleedings with the use of endoscopic technologies creates conditions for optimization of immediate and long-term outcomes of treatment. The polyethiologic nature of the disease and the significant specific gravity of severe combined pathology makes it urgent to introduce a multidisciplinary brigade principle for the treatment of ulcerative gastroduodenal bleeding. \u0000Key words: ulcerative gastroduodenal bleeding.","PeriodicalId":283981,"journal":{"name":"Vestnik of Experimental and Clinical Surgery","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122203030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-28DOI: 10.18499/2070-478X-2018-11-3-208-212
A. Nazarenko, Назаренко Алексей Витальевич, Y. Znatkova, Знаткова Яна Радиславовна, I. Sagaidak, Сагайдак Игорь Всеволодович, Tkachev Si, Ткачев Сергей Иванович, S. Alieva, Алиева Севил Богатуровна
Purpose. Control of pain syndrome in patients with locally advanced and recurrent pancreatic cancer using stereotactic radiation therapy (SBRT). Materials and methods. Our clinical observations relate to 103 patients with locally advanced (LAPC)and recurrent pancreatic cancer who received radiation therapy in the radiological unit of the NIITs NMI. NN Blokhin "in the periods: 2000-2010. and 2010-2015. The first group consisted of 77 patients with locally advanced non-resectable pancreatic cancer, of which (1a subgroup), 30 patients received radiotherapy in a classical fractionation regimen of 54-60 Gy/5 fraction, 40 patients (1b subgroup) in a mode of hypofractionation. per week 37.5 Gy/5 fraction. Group 2: 26 patients with recurrent pancreatic cancer, including 15 patients (2a subgroup), radiation therapy was performed in the classical fractionation regimen of 54-60 Gy/5 fraction, 11 patients (2b subgroup) underwent a course of radiation therapy in the mode of hypofractionation. Gr 5 times a week 37.5 Gy/5 fraction. Results. In SBRT, in 70% of cases, there was a reduction of all types of pain syndrome compared to 37.8% in the control group. The conclusion. Stereotactic beam therapy in the mode of hypofractionation is a highly effective, safe method of radiotherapy that effectively reduces pain syndrome in unresectable pancreatic cancer in a short time of treatment in comparison with the traditional method of radiotherapy, which significantly improves the quality of life of this severe category of patients.
{"title":"Application of Stereotactic Radiation Therapy for Removing Pain Syndrome to Patients with Non-researchable Cancer of Pancreas","authors":"A. Nazarenko, Назаренко Алексей Витальевич, Y. Znatkova, Знаткова Яна Радиславовна, I. Sagaidak, Сагайдак Игорь Всеволодович, Tkachev Si, Ткачев Сергей Иванович, S. Alieva, Алиева Севил Богатуровна","doi":"10.18499/2070-478X-2018-11-3-208-212","DOIUrl":"https://doi.org/10.18499/2070-478X-2018-11-3-208-212","url":null,"abstract":"Purpose. Control of pain syndrome in patients with locally advanced and recurrent pancreatic cancer using stereotactic radiation therapy (SBRT). \u0000Materials and methods. Our clinical observations relate to 103 patients with locally advanced (LAPC)and recurrent pancreatic cancer who received radiation therapy in the radiological unit of the NIITs NMI. NN Blokhin \"in the periods: 2000-2010. and 2010-2015. The first group consisted of 77 patients with locally advanced non-resectable pancreatic cancer, of which (1a subgroup), 30 patients received radiotherapy in a classical fractionation regimen of 54-60 Gy/5 fraction, 40 patients (1b subgroup) in a mode of hypofractionation. per week 37.5 Gy/5 fraction. Group 2: 26 patients with recurrent pancreatic cancer, including 15 patients (2a subgroup), radiation therapy was performed in the classical fractionation regimen of 54-60 Gy/5 fraction, 11 patients (2b subgroup) underwent a course of radiation therapy in the mode of hypofractionation. Gr 5 times a week 37.5 Gy/5 fraction. \u0000Results. In SBRT, in 70% of cases, there was a reduction of all types of pain syndrome compared to 37.8% in the control group. \u0000The conclusion. Stereotactic beam therapy in the mode of hypofractionation is a highly effective, safe method of radiotherapy that effectively reduces pain syndrome in unresectable pancreatic cancer in a short time of treatment in comparison with the traditional method of radiotherapy, which significantly improves the quality of life of this severe category of patients.","PeriodicalId":283981,"journal":{"name":"Vestnik of Experimental and Clinical Surgery","volume":"105 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129289521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-28DOI: 10.18499/2070-478x-2018-11-3-183-185
G. V. Yarovenko, Яровенко Галина Викторовна, A. V. Fesun, Фесюн Алексей Витальевич
According to modern data, there are no signs of chronic venous disease in only 15.9% of people. Observing the clinical data of recent years, there is a tendency to increase the number of people with venous diseases and, unfortunately, the number of young patients is increasing (there are data that schoolchildren of the senior classes have signs of varicose transformation in 10-15%). Polymorphism of matrix metalloproteinase-12 is a key link in the pathogenesis of varicose veins.We conducted surveys of 50 patients. The average age is 43.7 ± 15.9 years, of them women 32, men 18 people. All patients with the class C2-C6 varicose veins (CEAP-classifier) were divided into two groups by the method of serial sampling: group I (n = 20) - with relapse of varicose veins; Group II (n = 30) - patients treated with varicose disease for the first time. The only exception was patients with deferred vein thrombosis. Ultrasound diagnosis of the main veins of the lower extremities and genomic analysis of blood samples of patients was used.The obtained results confirm that in patients of the I group the MMP-12 gene occurs in 80% of cases (homo- and heterozygous variation), whereas in group II only in 33.3% of cases. The Pearson consensus criterion is 10.4 (the critical value of the criterion is 6.63). The significance level of this relationship corresponds to p <0.01. The statistical significance of the frequency of recurrence of varicose disease and the MMP-12 gene was established using the Spearman rank correlation coefficient, which is equal to 1,000 (criterion value is 0.398). Dependence of signs is statistically significant, with p <0.05
{"title":"Relapse of varicose veins of lower extremities","authors":"G. V. Yarovenko, Яровенко Галина Викторовна, A. V. Fesun, Фесюн Алексей Витальевич","doi":"10.18499/2070-478x-2018-11-3-183-185","DOIUrl":"https://doi.org/10.18499/2070-478x-2018-11-3-183-185","url":null,"abstract":"According to modern data, there are no signs of chronic venous disease in only 15.9% of people. Observing the clinical data of recent years, there is a tendency to increase the number of people with venous diseases and, unfortunately, the number of young patients is increasing (there are data that schoolchildren of the senior classes have signs of varicose transformation in 10-15%). Polymorphism of matrix metalloproteinase-12 is a key link in the pathogenesis of varicose veins.We conducted surveys of 50 patients. The average age is 43.7 ± 15.9 years, of them women 32, men 18 people. All patients with the class C2-C6 varicose veins (CEAP-classifier) were divided into two groups by the method of serial sampling: group I (n = 20) - with relapse of varicose veins; Group II (n = 30) - patients treated with varicose disease for the first time. The only exception was patients with deferred vein thrombosis. Ultrasound diagnosis of the main veins of the lower extremities and genomic analysis of blood samples of patients was used.The obtained results confirm that in patients of the I group the MMP-12 gene occurs in 80% of cases (homo- and heterozygous variation), whereas in group II only in 33.3% of cases. The Pearson consensus criterion is 10.4 (the critical value of the criterion is 6.63). The significance level of this relationship corresponds to p <0.01. The statistical significance of the frequency of recurrence of varicose disease and the MMP-12 gene was established using the Spearman rank correlation coefficient, which is equal to 1,000 (criterion value is 0.398). Dependence of signs is statistically significant, with p <0.05","PeriodicalId":283981,"journal":{"name":"Vestnik of Experimental and Clinical Surgery","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126180602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-28DOI: 10.18499/2070-478X-2018-11-3-224-228
N. A. Okunev, A. I. Okuneva, A. Shilov, V. Balashov, O. A. Shchekin
Relevance. Hemangiomas are the most common variety among tumors of the skin and soft tissues in children. The number of patients with this pathology is currently increasing. There are many methods to therapy hemangiomas in children. Currently, such drugs as Propranolol and Kenalog are widely used in the treatment of this pathology. Aim. Study the effect of β - blockers and the preparation of Kenalog on the tissues of the experimental model of hemangioma with simultaneous introduction. Materials and methods. For the experimental study, 20 live chickens were used. The histological structure of the vascular or capillary zone of the crest of the chicken resembles the human angioma. All chickens were divided into 4 groups of 5 individuals. Observing the general condition of chickens, macroscopic and histological examination of the crest of the hens were carried out. Results and conclusions. By the 15th day, all the chickens from the experimental group had died presumably because of massive vascular thrombosis. According to the result given above, simultaneous ingestion of β-blockers and interstitial administration of the Kenalog product are not recommended because of the possibility of thrombus formation and a high probability of death.
{"title":"Morphological changes in the tissues of the experimental model of hemangioma with concurrent medication of β-blockers and interstitial introduction of the Kenalog preparation.","authors":"N. A. Okunev, A. I. Okuneva, A. Shilov, V. Balashov, O. A. Shchekin","doi":"10.18499/2070-478X-2018-11-3-224-228","DOIUrl":"https://doi.org/10.18499/2070-478X-2018-11-3-224-228","url":null,"abstract":"Relevance. Hemangiomas are the most common variety among tumors of the skin and soft tissues in children. The number of patients with this pathology is currently increasing. There are many methods to therapy hemangiomas in children. Currently, such drugs as Propranolol and Kenalog are widely used in the treatment of this pathology. \u0000Aim. Study the effect of β - blockers and the preparation of Kenalog on the tissues of the experimental model of hemangioma with simultaneous introduction. \u0000Materials and methods. For the experimental study, 20 live chickens were used. The histological structure of the vascular or capillary zone of the crest of the chicken resembles the human angioma. All chickens were divided into 4 groups of 5 individuals. Observing the general condition of chickens, macroscopic and histological examination of the crest of the hens were carried out. \u0000Results and conclusions. By the 15th day, all the chickens from the experimental group had died presumably because of massive vascular thrombosis. According to the result given above, simultaneous ingestion of β-blockers and interstitial administration of the Kenalog product are not recommended because of the possibility of thrombus formation and a high probability of death.","PeriodicalId":283981,"journal":{"name":"Vestnik of Experimental and Clinical Surgery","volume":"154 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132670112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-28DOI: 10.18499/2070-478X-2018-11-3-229
A. Andreev, A. Ostroushko
Mayat Valentin Sergeevich - surgeon, doctor of medical sciences (1946), professor (1950), Honored Worker of Science of the Russian Federation, Hero of Socialist Labor (1969), laureate of the USSR State Prize (1976, 1987).Mayat Valentin Sergeevich was born in 1903. After the termination of the 2nd Moscow University he worked in a hospital surgical clinic (since 1925), served in the Red Army (since 1939). During the Great Patriotic War - the leading surgeon of the Penza evacuation hospital No. 1649 (since October 1941), the chief surgeon of the evacuation hospitals in the Penza region (from August 1942 to August 1945). In 1949, V.S. Majat worked in the People's Republic of China (PRC) in the surgical department of the government hospital, while lecturing at Peking University. After returning from the PRC, he was elected the head of the Department of Hospital Surgery of the 2nd Moscow Medical Institute (1953), simultaneously (1952-1964) was deputy chief surgeon and then chief surgeon of the 4th Main Directorate of the Ministry of Health of the USSR (until 1974). He developed a new method of phalloplasty, the classification of gunshot joint injuries. He prepared 14 doctors and 47 candidates of medical sciences, published over 250 scientific papers, author of 3 monographs, including on the topic: "Carotid artery surgery" (1966), which was awarded the NN Prize. Burdenko. Honorary member of the Moscow (1973), Georgian (1976), All-Union (1978) scientific surgical societies, a member of the International Society of Surgeons. He was awarded the Order of Lenin, the Red Banner of Labor, the Second World War, several foreign orders and medals.
{"title":"Mayat Valentin Sergeevich - a well-known scientist, surgeon, teacher, creator of the surgical scientific school (on the 115th anniversary of his birth)","authors":"A. Andreev, A. Ostroushko","doi":"10.18499/2070-478X-2018-11-3-229","DOIUrl":"https://doi.org/10.18499/2070-478X-2018-11-3-229","url":null,"abstract":"Mayat Valentin Sergeevich - surgeon, doctor of medical sciences (1946), professor (1950), Honored Worker of Science of the Russian Federation, Hero of Socialist Labor (1969), laureate of the USSR State Prize (1976, 1987).Mayat Valentin Sergeevich was born in 1903. After the termination of the 2nd Moscow University he worked in a hospital surgical clinic (since 1925), served in the Red Army (since 1939). During the Great Patriotic War - the leading surgeon of the Penza evacuation hospital No. 1649 (since October 1941), the chief surgeon of the evacuation hospitals in the Penza region (from August 1942 to August 1945). In 1949, V.S. Majat worked in the People's Republic of China (PRC) in the surgical department of the government hospital, while lecturing at Peking University. After returning from the PRC, he was elected the head of the Department of Hospital Surgery of the 2nd Moscow Medical Institute (1953), simultaneously (1952-1964) was deputy chief surgeon and then chief surgeon of the 4th Main Directorate of the Ministry of Health of the USSR (until 1974). He developed a new method of phalloplasty, the classification of gunshot joint injuries. He prepared 14 doctors and 47 candidates of medical sciences, published over 250 scientific papers, author of 3 monographs, including on the topic: \"Carotid artery surgery\" (1966), which was awarded the NN Prize. Burdenko. Honorary member of the Moscow (1973), Georgian (1976), All-Union (1978) scientific surgical societies, a member of the International Society of Surgeons. He was awarded the Order of Lenin, the Red Banner of Labor, the Second World War, several foreign orders and medals.","PeriodicalId":283981,"journal":{"name":"Vestnik of Experimental and Clinical Surgery","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128430610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-28DOI: 10.18499/2070-478X-2018-11-3-231
Andreev Alexander Alexeevich, A. Ostroushko
Dobrovol'skaya Nadezhda was born in 1878 in Kiev province. After graduating with a gold medal of the women's gymnasium in Kiev Women's medical Institute in Petrograd, worked as an Intern in the clinic of Professor M. S. Subbotin (1902-1904), later a country doctor . 1907 – the assistant to the dissector, assistant Professor of Women's medical Institute (until 1917), supernumeraries medical surgical Academy in Petrograd (from 1914). Since 1911 – a doctor of medicine. In 1912 N.. A. suggested method of joining vessels of different diameter, "end-to-end" crossing them obliquely; I applied the hair to perform a vascular suture. 24 APR 1917 N..Dobrovolskaya apply in Tartu University about acceptance as a privatdozent at the Department of surgery. 14 Oct 1918 – the Board of the University of Voronezh electing her to the chair of surgical pathology with the dressing and the doctrine about dislocations and fractures of the medical faculty and became the first woman to lead the Department of surgery. In 1919, she described the symptom that got her name – a decrease in heart rate when Paltseva the compression of the artery proximal to arteriovenous fistula. To link their fate with the Soviet authorities she did not dare, and soon left Voronezh. N.. Dobrovolskaya served as a doctor in Wrangel's army, which retreated in the Crimea and were evacuated to Egypt (1920-1922). In 1921 N.. Take the art to the newly opened in France, the laboratory organised by the Pasteur Institute and the radium Institute (later, the Institute Curie), which was first headed by Professor Claude REGO, and then N.. Dobrovolskaya. It describes the brachyury mutation in mice is becoming one of the pioneers in understanding the development of the body as changes in gene expression, creates several pure lines of mice as models of human diseases. Nadezhda was a member of the boards of the society of Russian doctors of Mechnikov, Russian academic group, Russian section of the International Federation of University women, Association of Russian doctors abroad. Collaborated in the Brotherhood of the Martyr Albania and St. Sergius. N.. Dobrovolska has authored over one hundred scientific papers. In 1937 she was awarded the French Academy of Sciences for research in the field of hereditary cancer. In 1954, at the age of 76 N..Dobrovolskaya is dead.
{"title":"140-th anniversary of the birth of the first in Russia head of the department of surgery, a well-known radiobiologist, geneticist and oncologist, Professor Nadezhda Alekseevna Dobrovolskaya (on the 100th anniversary of the Voronezh State medical university)","authors":"Andreev Alexander Alexeevich, A. Ostroushko","doi":"10.18499/2070-478X-2018-11-3-231","DOIUrl":"https://doi.org/10.18499/2070-478X-2018-11-3-231","url":null,"abstract":"Dobrovol'skaya Nadezhda was born in 1878 in Kiev province. After graduating with a gold medal of the women's gymnasium in Kiev Women's medical Institute in Petrograd, worked as an Intern in the clinic of Professor M. S. Subbotin (1902-1904), later a country doctor . 1907 – the assistant to the dissector, assistant Professor of Women's medical Institute (until 1917), supernumeraries medical surgical Academy in Petrograd (from 1914). Since 1911 – a doctor of medicine. In 1912 N.. A. suggested method of joining vessels of different diameter, \"end-to-end\" crossing them obliquely; I applied the hair to perform a vascular suture. 24 APR 1917 N..Dobrovolskaya apply in Tartu University about acceptance as a privatdozent at the Department of surgery. 14 Oct 1918 – the Board of the University of Voronezh electing her to the chair of surgical pathology with the dressing and the doctrine about dislocations and fractures of the medical faculty and became the first woman to lead the Department of surgery. In 1919, she described the symptom that got her name – a decrease in heart rate when Paltseva the compression of the artery proximal to arteriovenous fistula. To link their fate with the Soviet authorities she did not dare, and soon left Voronezh. N.. Dobrovolskaya served as a doctor in Wrangel's army, which retreated in the Crimea and were evacuated to Egypt (1920-1922). In 1921 N.. Take the art to the newly opened in France, the laboratory organised by the Pasteur Institute and the radium Institute (later, the Institute Curie), which was first headed by Professor Claude REGO, and then N.. Dobrovolskaya. It describes the brachyury mutation in mice is becoming one of the pioneers in understanding the development of the body as changes in gene expression, creates several pure lines of mice as models of human diseases. Nadezhda was a member of the boards of the society of Russian doctors of Mechnikov, Russian academic group, Russian section of the International Federation of University women, Association of Russian doctors abroad. Collaborated in the Brotherhood of the Martyr Albania and St. Sergius. N.. Dobrovolska has authored over one hundred scientific papers. In 1937 she was awarded the French Academy of Sciences for research in the field of hereditary cancer. In 1954, at the age of 76 N..Dobrovolskaya is dead.","PeriodicalId":283981,"journal":{"name":"Vestnik of Experimental and Clinical Surgery","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123504275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-28DOI: 10.18499/2070-478X-2018-11-3-202-207
V. A. Ananev, Ананьев Владимир Александрович, V. Lubyansky, Лубянский Владимир Григорьевич
The article provides up-to-date statistics on the prevalence of purulent pyelonephritis in Russia, shows the pathogenesis of purulent pyelonephritis in terms of circulatory disorders in the kidney for example 23 patients operated personally by the author in Urology conditions of the Altai Krai hospital on his own technique in the period 2016 by 2017. Morphological studies were carried out in the Department of pathologic Anatomy. Assess the morphological distortion in the kidney with significant changes in the mikrocirkuljatornom vein during the operation of the apostem zone, perifokalnogo zone of inflammation around 1 cm from the pockets of destruction and of apparently healthy sections of kidney the same kidney parenchyma jelektronnomikroskopicheskim method. Additionally investigated plots tissues of the kidneys removed due to have resulted them irreversible destructive changes. Irreversible development of acute purulent pyelonephritis associated with renal tissue ischemia and to achieve good results in the treatment of patients, appropriate action must be taken to restore the lost blood flow.
{"title":"Circulatory Condition in Kidney Patients with Pururlent Pyelonephritis","authors":"V. A. Ananev, Ананьев Владимир Александрович, V. Lubyansky, Лубянский Владимир Григорьевич","doi":"10.18499/2070-478X-2018-11-3-202-207","DOIUrl":"https://doi.org/10.18499/2070-478X-2018-11-3-202-207","url":null,"abstract":"The article provides up-to-date statistics on the prevalence of purulent pyelonephritis in Russia, shows the pathogenesis of purulent pyelonephritis in terms of circulatory disorders in the kidney for example 23 patients operated personally by the author in Urology conditions of the Altai Krai hospital on his own technique in the period 2016 by 2017. Morphological studies were carried out in the Department of pathologic Anatomy. Assess the morphological distortion in the kidney with significant changes in the mikrocirkuljatornom vein during the operation of the apostem zone, perifokalnogo zone of inflammation around 1 cm from the pockets of destruction and of apparently healthy sections of kidney the same kidney parenchyma jelektronnomikroskopicheskim method. Additionally investigated plots tissues of the kidneys removed due to have resulted them irreversible destructive changes. \u0000Irreversible development of acute purulent pyelonephritis associated with renal tissue ischemia and to achieve good results in the treatment of patients, appropriate action must be taken to restore the lost blood flow.","PeriodicalId":283981,"journal":{"name":"Vestnik of Experimental and Clinical Surgery","volume":"130 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133098726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-28DOI: 10.18499/2070-478X-2018-11-3-154-160
B. Sukovatykh, A. A. Netiaga, Yuriy Yurievich Blinkov, Y. Polevoy, V. A. Zhukovskii
Importance of the topic. One of the directions of improving hernioplasty efficiency with the use of light synthetic materials is including the strengthening zones in their structure. Purpose. To compare functional effectiveness of the light and the light strengthened polypropylene endoprostheses for hernioplasty on the base of studying biomechanical characteristics of anterior abdominal wall tissues after their implantation in experiment. Materials and methods. Experimental studies were conducted on 36 rabbits of “chinchilla” breed. All animals were divided into 2 series of experiments. In the first (control) series the light polypropylene endoprosthesis was implanted, while in the second (experimental) series there was used a new cancellated endoprosthesis from monofilamentous polypropylene, consisting of the basic and strengthened zones in the form of horizontally located, alternating with each other monothreads of the higher thickness. Pathomorphological changes and biomechanical properties of the abdominal wall tissues were studied macroscopically in the experiment by implantation of endoprostheses in onlay position on the 7th, 30th and 90th days. Results and their discussion. There was proved that in direction of the loop column as well as in the loop row after implantation of the studied materials breaking load increased from the 7th to the 90th day of experiment, that was related to the formation of the connective tissue capsule around materials. The light strengthened endoprosthesis was more durable and stronger in 1,6 times compare to the light analog at all stages of observation. Along the loop column there was no significant difference detected. In both series of experiment in the direction of the loop column as well as in loop row the reduction of sample lengthening took place. Along the loop column indicators of lengthening, characterizing elasticity of the prosthesis aponeurosis, in the series of the light strengthened endoprosthesis were 1,4-1,6 times lower than in its light analog. Along the loop row there was no significant difference of indicators. Conclusion. Introduction of the strengthened zones in a light endoprosthesis increases its durability with preservation of the material’s elasticity.
{"title":"Biomechanical Characteristics of Light Synthetic Materials for Hernioplasty (Experimental Study)","authors":"B. Sukovatykh, A. A. Netiaga, Yuriy Yurievich Blinkov, Y. Polevoy, V. A. Zhukovskii","doi":"10.18499/2070-478X-2018-11-3-154-160","DOIUrl":"https://doi.org/10.18499/2070-478X-2018-11-3-154-160","url":null,"abstract":"Importance of the topic. One of the directions of improving hernioplasty efficiency with the use of light synthetic materials is including the strengthening zones in their structure. \u0000Purpose. To compare functional effectiveness of the light and the light strengthened polypropylene endoprostheses for hernioplasty on the base of studying biomechanical characteristics of anterior abdominal wall tissues after their implantation in experiment. \u0000Materials and methods. Experimental studies were conducted on 36 rabbits of “chinchilla” breed. All animals were divided into 2 series of experiments. In the first (control) series the light polypropylene endoprosthesis was implanted, while in the second (experimental) series there was used a new cancellated endoprosthesis from monofilamentous polypropylene, consisting of the basic and strengthened zones in the form of horizontally located, alternating with each other monothreads of the higher thickness. Pathomorphological changes and biomechanical properties of the abdominal wall tissues were studied macroscopically in the experiment by implantation of endoprostheses in onlay position on the 7th, 30th and 90th days. \u0000Results and their discussion. There was proved that in direction of the loop column as well as in the loop row after implantation of the studied materials breaking load increased from the 7th to the 90th day of experiment, that was related to the formation of the connective tissue capsule around materials. The light strengthened endoprosthesis was more durable and stronger in 1,6 times compare to the light analog at all stages of observation. Along the loop column there was no significant difference detected. In both series of experiment in the direction of the loop column as well as in loop row the reduction of sample lengthening took place. Along the loop column indicators of lengthening, characterizing elasticity of the prosthesis aponeurosis, in the series of the light strengthened endoprosthesis were 1,4-1,6 times lower than in its light analog. Along the loop row there was no significant difference of indicators. \u0000Conclusion. Introduction of the strengthened zones in a light endoprosthesis increases its durability with preservation of the material’s elasticity.","PeriodicalId":283981,"journal":{"name":"Vestnik of Experimental and Clinical Surgery","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125432393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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