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Exploring Parental Views of Remote Vision Testing in Children. 探讨家长对儿童远程视力测试的看法。
Q3 Medicine Pub Date : 2026-07-06 eCollection Date: 2026-01-01 DOI: 10.22599/bioj.541
Kiran Pannu-Dhillon, Ahalya Subramanian, Miriam Conway

Background: The rise of digital technologies has enabled vision testing via applications on phones, tablets, and computers, allowing assessments beyond clinical settings. While these tools empower parents to test their children's vision at home, little is known about the attitudes of parents in the United Kingdom (UK) toward this approach. This study examines parents perceived benefits and challenges of conducting vision tests for young children at home, either independently or with the help of a qualified clinician.

Research aim: This qualitative study explores parents' perspectives on at-home remote vision testing in a paediatric population.

Methodology: Data was collected via two online focus groups with parents of children aged 4-8 years old. Sessions were recorded, transcribed, and thematically coded to identify key patterns and themes.

Results: Five key themes emerged: navigating trust in remote vision testing, impact of child demographics, desire for professional support, digital enablers and barriers, and appointment frequency influences desire for remote testing. Parents emphasised the need for training in remote vision testing to build confidence and skill. Potential benefits included reduced travel, time off work/school, and greater flexibility. Concerns around test accuracy, occlusion, and application use highlight the need for clear guidance and virtual supervision by professionals.

Conclusion: Remote vision testing could be a reliable alternative to clinic visits, provided parents receive adequate training and support. Participants expressed concerns about the reliability of remote vision testing, particularly for younger or less cooperative children, but acknowledged benefits such as reduced travel, lower costs, and greater flexibility. While app-based testing was appealing, most preferred professional involvement, either in person or virtually, to ensure accuracy, reassurance, and follow-up support.

背景:数字技术的兴起使得通过手机、平板电脑和电脑上的应用程序进行视力测试成为可能,从而使评估超越了临床环境。虽然这些工具使父母能够在家里测试孩子的视力,但人们对英国父母对这种方法的态度知之甚少。本研究调查了父母认为在家中为幼儿进行视力测试的好处和挑战,无论是独立的还是在合格临床医生的帮助下。研究目的:本定性研究探讨家长对儿童家庭远程视力测试的看法。方法:数据通过两个在线焦点小组与4-8岁儿童的父母收集。会议记录、转录和主题编码,以确定关键模式和主题。结果:出现了五个关键主题:远程视力测试中的导航信任,儿童人口统计学的影响,对专业支持的渴望,数字化的促成因素和障碍,预约频率影响远程测试的渴望。家长们强调需要进行远程视力测试培训,以建立信心和技能。潜在的好处包括减少旅行,有时间工作/上学,以及更大的灵活性。对测试准确性、遮挡和应用程序使用的关注突出了专业人员明确指导和虚拟监督的必要性。结论:如果家长得到充分的培训和支持,远程视力检查可以替代门诊就诊。与会者对远程视力测试的可靠性表示关切,特别是对年龄较小或不太合作的儿童,但也承认其好处,如减少旅行、降低成本和更大的灵活性。虽然基于应用程序的测试很有吸引力,但大多数人更喜欢专业人士的参与,无论是亲自还是虚拟的,以确保准确性、保证和后续支持。
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引用次数: 0
Frequency of Convergence Insufficiency Among Young Adults in a University Population. 大学人群中年轻人收敛性不全的频率。
Q3 Medicine Pub Date : 2026-05-19 eCollection Date: 2026-01-01 DOI: 10.22599/bioj.537
Nishanee Rampersad, Nashka Naidoo, Sibulelo Dzanibe, Husna Alli, Tasneem Makada, Owethu Mthethwa, Tamara Pillay, Minenhle Dube

Background: Convergence insufficiency (CI) is a binocular vision disorder that has been linked to increasing visual demands of near tasks. As young adults routinely perform many near-work tasks, often with digital devices, this study evaluated the frequency of CI among young adults in a university population.

Method: In this cross-sectional study, young adults aged 18-25 years were recruited using convenience sampling. Participants were excluded if they had any ocular pathology, clinically significant anisometropia, strabismus, accommodation insufficiency, reduced visual acuity and history of ocular conditions and vision therapy. Cover test, positive fusional vergence (PFV) and near point of convergence (NPC) were performed. The clinical diagnosis of CI was based on the CI and Reading Study group criteria. Data were analysed using descriptive and inferential statistics.

Results: The mean age of the sample (n = 192) was 21.1 ± 2.0 and consisted of more females (n = 106, 55%). Overall, 151 (79%) participants did not have CI while 41 (21%) had CI. In participants with CI, low suspect CI was most common (n = 26, 63%) followed by high suspect CI (n = 10, 24%) and definite CI (n = 5, 12%). Participants with CI had significantly higher NPC break and recovery values, larger exophoria measurements at distance and near and lower PFV break and recovery values (p < 0.001).

Conclusion: The findings show that CI was present in 21% of young adults in this university population. The test results, for NPC, prism cover test and PFV, in individuals with CI were significantly different from the test results in individuals without CI.

背景:会聚功能不全(CI)是一种双目视觉障碍,与近距离任务的视觉需求增加有关。由于年轻人经常使用数字设备执行许多与工作有关的任务,因此本研究评估了大学人群中年轻人CI的频率。方法:采用方便抽样的方法,选取18-25岁的青壮年为研究对象。如果参与者有任何眼部病理、临床上明显的屈光参差、斜视、调节功能不全、视力下降以及眼部疾病和视力治疗史,则被排除在外。进行覆盖检验、正融合收敛(PFV)和近收敛点(NPC)。CI的临床诊断基于CI和Reading研究组标准。数据分析采用描述性和推断性统计。结果:192例患者的平均年龄为21.1±2.0岁,其中女性居多(106,55%)。总的来说,151名(79%)参与者没有CI, 41名(21%)参与者有CI。在CI的参与者中,低怀疑CI最常见(n = 26, 63%),其次是高怀疑CI (n = 10, 24%)和明确CI (n = 5, 12%)。CI患者鼻咽癌破裂和恢复值显著较高,远、近距离外径测量值较大,PFV破裂和恢复值较低(p < 0.001)。结论:研究结果表明,该大学人群中21%的年轻人存在CI。CI组NPC、prism cover test和PFV的检测结果与非CI组有显著性差异。
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引用次数: 0
Testing Accommodation: The Case for Nott Dynamic Retinoscopy in Orthoptic Assessments. 测试适应性:非动态视网膜镜在正视评估中的应用。
Q3 Medicine Pub Date : 2026-04-28 eCollection Date: 2026-01-01 DOI: 10.22599/bioj.550
Sonia Toor, Jessica E Francis

Introduction: Accommodation is most commonly assessed using the RAF Rule. However, this subjective test has multiple sources of error, and an objective measurement of accommodation using Nott dynamic retinoscopy may be a more appropriate test to use. This study aimed to compare Nott dynamic retinoscopy with the RAF Rule and the Plusoptix PowerRef III (gold standard) after a period of close work, to determine whether this is a more suitable test for measuring accommodation.

Methods: Accommodation was measured in 25 students before and after 30 minutes of close work using the RAF Rule, Nott dynamic retinoscopy, and the Plusoptix. The RAF Rule measured the amplitude of accommodation when viewing N5 print. Nott dynamic retinoscopy assessed the lead/lag of accommodation using the UC Cube with N5 print at 40 cm. The Plusoptix measured objective accommodation (slope and response) in binocular and uniocular conditions.

Results: The Plusoptix and Nott dynamic retinoscopy detected accommodative lag within normal limits (under 1D), with no significant change after close work (p > 0.05). No significant change in accommodation after close work was found with the RAF Rule tested uniocularly (p > 0.05); however, a significant decrease in amplitude of accommodation from 12.85D to 11.26D was found when tested binocularly. The Plusoptix confirmed that this was not due to convergence fatigue (p > 0.05).

Discussion: The measurement variations observed with the binocular RAF Rule confirm that the subjective nature of the RAF Rule test makes it more prone to errors. Nott dynamic retinoscopy is comparable to the gold standard Plusoptix; therefore, we suggest that Nott dynamic retinoscopy should be used in the orthoptic assessment of accommodation.

简介:住宿通常使用皇家空军规则进行评估。然而,这种主观测试有多种误差来源,使用Nott动态视网膜镜进行调节的客观测量可能是更合适的测试。本研究旨在经过一段时间的密切工作,将Nott动态视网膜镜检查与RAF规则和Plusoptix PowerRef III(金标准)进行比较,以确定这是否是一种更适合测量调节的测试。方法:使用RAF规则、Nott动态视网膜镜和Plusoptix测量25名学生在近距离工作前和30分钟后的适应能力。RAF规则测量了观看N5印刷品时的调节幅度。Nott动态视网膜镜检查使用40厘米处带有N5打印的UC Cube评估调节的超前/滞后。Plusoptix在双眼和单眼条件下测量物镜调节(斜率和响应)。结果:Plusoptix和Nott动态视网膜镜检测到调节滞后在正常范围内(1D下),近距离工作后无明显变化(p < 0.05)。单眼测试RAF规则后,在近距离工作后,没有发现明显的住宿变化(p > 0.05);然而,当双眼测试时,调节幅度从12.85D显著下降到11.26D。Plusoptix证实这不是由于会聚疲劳(p > 0.05)。讨论:用双目RAF规则观察到的测量变化证实了RAF规则测试的主观性使其更容易出错。Nott动态视网膜镜可与黄金标准Plusoptix媲美;因此,我们建议使用Nott动态视网膜镜评估调节。
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引用次数: 0
Progressive Supranuclear Palsy (PSP): An Orthoptic Assessment. 进行性核上性麻痹(PSP):一种正视评估。
Q3 Medicine Pub Date : 2026-04-10 eCollection Date: 2026-01-01 DOI: 10.22599/bioj.505
Dominic Burdon, Stephen Mullin, Christopher Harris

Aim: Progressive supranuclear palsy (PSP) is an atypical Parkinsonian disorder which, like other atypical Parkinsonian disorders, displays neurological motor and oculomotor signs at different stages along the disease course. The overlap in presenting signs between the disorders presents a diagnostic challenge for the clinician, particularly early on. Here we audit the role of orthoptic oculomotor and eye-tracker assessment for atypical Parkinsonian patients.

Method: A retrospective analysis was conducted for 26 patients with atypical Parkinsonian signs, referred to orthoptics for oculomotor assessment. Orthoptic diagnoses were made after reviewing oculomotor range, doll's head manoeuvre, saccadic velocity, vergence, eyelid signs and fixation results. The orthoptic diagnoses were compared with the final neurology/neurosurgery diagnosis for consistency.

Results: Of the 19/26 cases who were diagnosed with 'suspected PSP' after orthoptic assessment, 14/19 (73.68%) had a final diagnosis of 'suspected PSP' by neurology/neurosurgery. In 5/19 cases (26.32%) the patients demonstrated PSP-like signs in orthoptics but later received alternative diagnoses. The orthoptic diagnosis was consistent with the final neurology/neurosurgery diagnosis for 'suspected non-PSP' in all seven cases.

Conclusion: Suspected diagnoses after orthoptic assessment were consistent with the final neurology/neurosurgery department diagnoses in 80.77% of patients. We conclude that early orthoptic oculomotor and eye tracker assessment of atypical Parkinsonian patients is clinically effective for ruling PSP in or out of the clinical picture.

目的:进行性核上性麻痹(PSP)是一种非典型帕金森病,与其他非典型帕金森病一样,在病程的不同阶段表现出神经运动和动眼肌体征。这两种疾病在表现症状上的重叠对临床医生来说是一个诊断挑战,尤其是在早期。在这里,我们审计的作用,正视动眼仪和眼动仪评估非典型帕金森患者。方法:回顾性分析26例非典型帕金森症状患者,参照正视镜进行眼肌运动评估。通过观察眼球运动范围、娃娃头部运动、眼球跳速、眼球散度、眼睑体征和注视结果,进行了正视诊断。将正视镜诊断与最终的神经病学/神经外科诊断进行比较,以确保一致性。结果:在19/26例经正视检查诊断为“疑似PSP”的患者中,14/19(73.68%)经神经内科/神经外科最终诊断为“疑似PSP”。5/19例(26.32%)患者在正视镜中表现出psp样征象,但后来接受了其他诊断。在所有7例中,正视镜诊断与最终的神经病学/神经外科诊断“疑似非psp”一致。结论:80.77%的患者经正视镜评估后的疑似诊断与神经内科/神经外科的最终诊断一致。我们的结论是,非典型帕金森患者的早期正视动眼仪和眼动仪评估在临床上有效地判断PSP是否存在。
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引用次数: 0
Asthenopia in Postgraduate Surgical Trainees: Prevalence and Correlation With Refractive and Orthoptic Parameters. 研究生外科受训人员的视弱视:屈光和正视参数的患病率和相关性。
Q3 Medicine Pub Date : 2026-04-09 eCollection Date: 2026-01-01 DOI: 10.22599/bioj.481
Aashi Bansal, Sakshi Meshram, Shreya Thatte, Shreya Mahanaik, Anupriya Kesharwani

Purpose: Association of asthenopia with multiple professions involving prolonged near work is well-established but asthenopia is under-reported in postgraduate surgical trainees. The purpose of this study was to determine the prevalence of asthenopia in surgical trainees and determine the associated risk factors.

Methods: This study was an institute-based observational study, conducted between July 2024 and September 2024. Out of 107 surgical trainees, 102 responded to a structured asthenopia questionnaire. Detailed ophthalmic evaluation was performed in 43 trainees who consented and presented voluntarily. Visual acuity (Snellen), cover test (near and distance), positive (PFV) and negative fusional vergence (using a prism bar at near and distance), stereoacuity (Randot), near point of convergence, near point of accommodation and accommodative amplitude (using the Royal Air Force rule) were measured. Statistical analysis was performed using SPSS 22.

Results: The prevalence of asthenopia was found to be 67.6%. The highest prevalence was found in Ophthalmology trainees. Out of 43 who presented for orthoptic assessment, 11 were advised to pursue refractive correction. PFV near was significantly lower in trainees with asthenopia (mean = 10.1 PD) compared to those without asthenopia (mean = 15.1), p = 0.03.

Conclusion: Asthenopia among surgical trainees was high. The visual precision needed for surgical procedures, lack of sleep and the extensive academic curriculum may contribute to asthenopia in surgical trainees. Routine ophthalmic and orthoptic testing may help alleviate symptoms.

目的:弱视与多种职业涉及长时间近距离工作的关联是公认的,但在研究生外科培训生中弱视的报道不足。本研究的目的是确定外科受训人员视疲劳的患病率,并确定相关的危险因素。方法:本研究是一项以研究所为基础的观察性研究,于2024年7月至2024年9月进行。在107名外科培训生中,102人回答了一份结构化的视疲劳问卷。对43名自愿前来就诊的受训者进行了详细的眼科评估。测量视力(Snellen)、覆盖测试(近距离和远距离)、正(PFV)和负融合聚光(近距离和远距离使用棱镜杆)、立体灵敏度(Randot)、近汇聚点、近调节点和调节幅度(使用皇家空军规则)。采用SPSS 22进行统计学分析。结果:患者视疲劳发生率为67.6%。以眼科见习生患病率最高。在43名接受视力评估的患者中,11人被建议进行屈光矫正。与非弱视组(平均15.1)相比,弱视组(平均10.1 PD)的PFV近值显著降低,p = 0.03。结论:外科培训生视疲劳程度较高。外科手术所需的视觉精度、睡眠不足和广泛的学术课程都可能导致外科受训者的视疲劳。常规眼科和正视检查可能有助于缓解症状。
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引用次数: 0
Comparison of Accommodative Response After Reading from Electronic Devices versus Hardcopy. 电子阅读与纸质阅读的适应性反应比较。
Q3 Medicine Pub Date : 2026-04-09 eCollection Date: 2026-01-01 DOI: 10.22599/bioj.483
Ruchika Sah, Manish Sah, Gayathri Prabhu Rajiva

Aim: To assess the change in accommodative response between electronic devices and hardcopy text after prolonged reading.

Method: There were 30 participants (N = 30), with a mean age of 24.29 ± 5.21 years. The accommodative response (lag or lead of accommodation, amplitude of accommodation, and accommodative facility) was measured before and after reading for 60 minutes from a printed book, a smartphone, and a laptop, with a 24-hour break between tasks. Secondary outcomes included comparisons of accommodative responses between hardcopy text and smartphone, smartphone and laptop, and laptop and hardcopy text.

Results: Accommodative lag was initially 0.50 ± 0.00 D, with significant increases observed after 60 minutes of reading from a smartphone (1.25 ± 0.50 D), a laptop (1.75 ± 0.50 D), and a hardcopy text (1.50 ± 0.25 D). A greater lag was noted with laptop use compared to smartphone reading (P < 0.01). Accommodative facility was significantly reduced when reading from a laptop compared to both a smartphone (P < 0.01) and a hardcopy (P < 0.01). The binocular mean amplitude of accommodation was -7.50 ± 1.25 D with the laptop and -8.00 ± 1.00 D with the hardcopy, with a P-value of 0.085, indicating no statistically significant difference.

Conclusion: Prolonged near work significantly affects accommodative function, with laptops inducing the greatest accommodative lag and reduction in facility. Hardcopy reading preserved accommodative facility better than digital devices, while amplitude of accommodation showed minimal change. These results suggest that sustained laptop use may lead to greater visual strain compared to smartphones or printed text.

目的:评估长时间阅读后电子设备与纸质文本之间的适应性反应变化。方法:30例患者(N = 30),平均年龄(24.29±5.21)岁。调节反应(调节的滞后或领先、调节的幅度和调节设施)是在阅读印刷书籍、智能手机和笔记本电脑的60分钟前后测量的,任务之间有24小时的休息。次要结果包括比较硬拷贝文本和智能手机、智能手机和笔记本电脑、笔记本电脑和硬拷贝文本之间的适应性反应。结果:调节滞后最初为0.50±0.00 D,在智能手机(1.25±0.50 D)、笔记本电脑(1.75±0.50 D)和纸质文本(1.50±0.25 D)阅读60分钟后,调节滞后显著增加。与智能手机阅读相比,使用笔记本电脑阅读的延迟更大(P < 0.01)。与智能手机(P < 0.01)和硬拷贝(P < 0.01)相比,使用笔记本电脑阅读时,便利设施明显减少。笔记本电脑双眼平均调节幅度为-7.50±1.25 D,硬拷贝为-8.00±1.00 D, p值为0.085,差异无统计学意义。结论:长时间近距离工作显著影响调节功能,笔记本电脑最大程度地导致调节滞后和功能降低。与数字阅读相比,纸质阅读能更好地保存调节设施,而调节幅度变化最小。这些结果表明,与智能手机或打印文本相比,持续使用笔记本电脑可能会导致更大的视觉疲劳。
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引用次数: 0
Is Isolated Inferior Rectus Weakness a Strong Indicator for Myasthenia Gravis? 孤立的下直肌无力是重症肌无力的有力指标吗?
Q3 Medicine Pub Date : 2026-04-02 eCollection Date: 2026-01-01 DOI: 10.22599/bioj.502
Emma Butterworth, Jessy Choi, Martin Rhodes, Joshua Simmons

Background: Isolated inferior rectus weakness (IRW) has historically been reported as a possible presenting sign of myasthenia gravis (MG). Orthoptists often identify IRW, prompting further investigations. This service evaluation aims to determine whether patients with IRW or other symptoms were subsequently diagnosed with MG.

Methods: A retrospective review of patient case notes was conducted. The cohort included consecutive patients who presented to the adult strabismus service and received acetylcholine receptor antibody (ACR) testing between 2010 and 2023 at a tertiary referral centre in Sheffield.

Results: Sixty-two patients were included in the analysis. Patients were grouped based on isolated IRW, suspicion of thyroid eye disease, or the presence of MG characteristics. These characteristics included variable diplopia, ocular motility and ptosis; fatigue on elevation; Cogan's lid twitch; MG-like fatigue; and breathing or swallowing difficulties.Ten patients (16.13%) were diagnosed with MG. Of these, six (60%) had ocular MG (OMG). No patients in the isolated IRW group were found to have MG. All MG patients exhibited weakness of multiple extra-ocular muscles (EOM), ranging from 2 to 12 different muscles affected. Each had one or more characteristic MG symptoms or signs, with variability observed in 80% (n = 8).

Conclusion: No cases of MG were identified in patients with isolated IRW. All MG diagnoses were associated with characteristic signs or symptoms. This highlights the importance of detailed clinical history and orthoptic assessment when MG is suspected and poses further questions of whether isolated IRW needs further MG investigative testing.

背景:孤立性下直肌无力(IRW)历来被报道为重症肌无力(MG)的可能表现。骨科医生经常发现IRW,促使进一步调查。本服务评估旨在确定有IRW或其他症状的患者是否随后被诊断为MG。方法:对病例记录进行回顾性分析。该队列包括2010年至2023年间在谢菲尔德三级转诊中心接受成人斜视服务并接受乙酰胆碱受体抗体(ACR)检测的连续患者。结果:62例患者纳入分析。根据孤立的IRW、怀疑甲状腺眼病或MG特征对患者进行分组。这些特征包括可变复视、眼球运动和上睑下垂;高程疲劳;科根的眼皮抽搐了一下;MG-like疲劳;呼吸或吞咽困难。10例(16.13%)被诊断为MG。其中6例(60%)有眼部MG (OMG)。在孤立的IRW组中没有发现患者有MG。所有MG患者均表现多发性眼外肌(EOM)无力,受影响的肌肉从2到12块不等。每个人都有一种或多种特征性MG症状或体征,80% (n = 8)存在可变性。结论:孤立性IRW患者中未发现MG病例。所有MG诊断均与特征性体征或症状相关。这突出了当怀疑MG时详细的临床病史和正视镜评估的重要性,并提出了孤立IRW是否需要进一步MG调查性检查的进一步问题。
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引用次数: 0
Impact of Different Illumination Levels on Ocular Parameters in Healthy Adults During Book-Reading: An Experimental Study. 不同照度对健康成人阅读时眼参数影响的实验研究
Q3 Medicine Pub Date : 2026-04-01 eCollection Date: 2026-01-01 DOI: 10.22599/bioj.529
Vishal Biswas, Roshni Majumder, Supriya Awasthi, Rahul Singh

Aim: To determine the role of different levels of illumination on various binocular vision parameters.

Settings and design: An experimental study was conducted from October 2024-June 2025.

Methods: Thirty-four participants aged between 17 to 25 years with a mean age of 19.7 ± 2.4 years were included. Under different lighting conditions, i.e., low illumination (50 lux), medium illumination (100 lux), and high illumination (150 lux), the participants were instructed to perform reading tasks. The vergence and accommodative parameters for near were evaluated.

Results: Observed changes in binocular vision parameters were associated with varying illumination levels. At 50 lux, the binocular accommodative facility (BAF) was 6.97 ± 0.86 cpm; at 150 lux, it was 10.55 ± 1.04 cpm. Higher illumination significantly enhanced vergence facility (VF), near point of accommodation (NPA), and near point of convergence (NPC). Brighter illumination enhanced both positive and negative fusional vergence (PFV and NFV) values, while MEM retinoscopy demonstrated decrease of accommodative lag.

Conclusions: Binocular vision parameters were higher significantly with high illumination which can enhance visual performance. Proper lighting is essential for eye exams, digital device use, and workspace design.

目的:探讨不同光照水平对双目视觉参数的影响。环境与设计:实验研究时间为2024年10月至2025年6月。方法:纳入34例患者,年龄17 ~ 25岁,平均年龄19.7±2.4岁。在低照度(50勒克斯)、中等照度(100勒克斯)和高照度(150勒克斯)的不同照明条件下,指导参与者执行阅读任务。对近似的收敛性和适应性参数进行了评价。结果:观察到双目视觉参数的变化与不同光照水平有关。50勒克斯时,双眼调节系数(BAF)为6.97±0.86 cpm;在150勒克斯时为10.55±1.04 cpm。高照度显著增强了聚光设施(VF)、近调节点(NPA)和近会聚点(NPC)。较亮的光照增强了正、负融合散度(PFV和NFV)值,而MEM视网膜镜显示调节滞后降低。结论:高照度可显著提高双眼视觉参数,增强视觉功能。适当的照明对于眼科检查、数字设备使用和工作空间设计至关重要。
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引用次数: 0
Effect of Chromostereoscopic Stimulus on Accommodative Response and Subjective Perception. 立体色刺激对调节反应和主观知觉的影响。
Q3 Medicine Pub Date : 2026-03-04 eCollection Date: 2026-01-01 DOI: 10.22599/bioj.515
Vivek Suganthan Ramasubramanian, Kartheyaeni Jothi Madhavan, Shahid Afridi Hyder Ali, Johan Raj Jeyaraj, Swetha Selvakumar

Purpose: The phenomenon of chromostereopsis, where colours are perceived at different depths due to the eye's optics, creates a potential conflict during accommodation. This prospective, cross-sectional study aimed to investigate the effect of different chromostereoscopic stimuli on the objective accommodative response and subjective user comfort.

Methods: Thirty young, healthy adults (mean age 19.83 ± 1.18 years) read text passages presented on an iPad at a 50 cm viewing distance. Stimuli included red, green, blue, yellow, and mixed-colour text on a black background, compared to a standard black-on-white baseline. Accommodative lag was measured objectively using an open-field autorefractor, while subjective ratings of perceived depth and screen readability were collected via questionnaire.

Results: A significant main effect of stimulus colour on accommodative lag was found (p < .001). The short-wavelength (blue) stimulus induced the greatest mean accommodative lag (0.61 D). Conversely, the long-wavelength (red) stimulus produced the smallest lag (0.18 D), indicating the most accurate accommodative focus. Subjective data strongly corroborated these findings, with blue being perceived as most distant and most difficult to read (76.67% and 73.33% of participants, respectively), while red was perceived as closest and yellow was perceived as the easiest to read (53.33%).

Conclusion: Colour is a critical factor in visual ergonomics for dark-themed interfaces. A pure blue stimulus on a black background acts as a poor driver for accommodation, leading to significant focusing errors and a diminished perceptual experience. These findings provide a physiological basis for user interface design guidelines, suggesting that the use of short-wavelength, saturated text for reading tasks should be avoided to optimize visual comfort and performance.

目的:由于眼睛的光学系统,颜色在不同的深度被感知,这一现象在调节过程中产生了潜在的冲突。本前瞻性横断面研究旨在探讨不同立体色刺激对客观调节反应和主观用户舒适度的影响。方法:30名年轻健康成人(平均年龄19.83±1.18岁)在50 cm的观看距离上阅读iPad上呈现的文本文章。刺激物包括红色、绿色、蓝色、黄色和黑色背景上的混合色文本,与标准的黑白基线相比。调节滞后采用开场自折射镜客观测量,而主观评分的感知深度和屏幕可读性通过问卷收集。结果:刺激颜色对调节滞后有显著的主效应(p < 0.001)。短波长(蓝色)刺激诱导的平均调节滞后最大(0.61 D)。相反,长波长(红色)刺激产生的滞后最小(0.18 D),表明调节焦点最准确。主观数据有力地证实了这些发现,蓝色被认为是最遥远和最难阅读的(分别为76.67%和73.33%的参与者),而红色被认为是最接近的,黄色被认为是最容易阅读的(53.33%)。结论:颜色是深色主题界面的视觉人机工程学的关键因素。黑色背景上的纯蓝色刺激对调节的作用很差,导致明显的聚焦错误和减少的感知体验。这些发现为用户界面设计指南提供了生理基础,建议在阅读任务中应避免使用短波长、饱和的文本,以优化视觉舒适性和性能。
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引用次数: 0
Isolated Sixth Cranial Nerve Palsy as the First Presenting Sign of MOG Antibody-Associated Disease in a Three-Year-Old Child. 孤立性第六脑神经麻痹是三岁儿童MOG抗体相关疾病的第一表现。
Q3 Medicine Pub Date : 2026-03-02 eCollection Date: 2026-01-01 DOI: 10.22599/bioj.527
Courtney Healey, Lloyd Bender, Anna Zatorska, Lucas Tadeusz Ginter

Background: Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a neurological, autoimmune, demyelinating disorder. Clinical phenotypes differ between adults and children, and MOGAD is more commonly observed in the paediatric population compared to the adult population. Cases of isolated cranial nerve palsies as initial clinical phenotypes of MOGAD are rarely reported in the literature. Here, we report a child who presented with an isolated left sixth cranial nerve palsy as the initial sign of anti-myelin oligodendrocyte glycoprotein antibody associated disease (MOGAD).

Method: In this case study, we report on a three-year-old female known to the orthoptic and paediatric ophthalmology services due to an intermittent exotropia. The same child later develops an acute convergent deviation of the left eye preceded by a viral illness with no other systemic symptoms. This case reports on the clinical findings and treatment over a five-year period.

Results: Immunological investigations revealed positive oligoclonal bands in CSF but negative in serum. Serology was positive for MOG antibodies. Magnetic Resonance Imaging (MRI) showed acute demyelination in the pons and cerebellum with accompanying lesions in cerebral white matter bilaterally and incidental band heterotropia. The symptomatic lesion was found to be a small plaque in the left lower pons in the intrinsic course of the left sixth cranial nerve, suggestive of acute demyelination. The patient completed a five-day course of intravenous methylprednisolone 30 mg/kg daily, followed by a reducing course of oral prednisolone.

Follow up discussion: Although brain stem involvement in MOGAD is common, isolated cranial palsies are rare and are not commonly reported as presenting symptoms in children (Barr et al., 2000). Patients with MOG positive antibodies have relatively favourable outcomes. Here, we highlight the importance of considering MOGAD in the differential diagnosis of isolated cranial nerve palsies, particularly in the paediatric population.

背景:髓鞘少突胶质细胞糖蛋白抗体相关疾病(MOGAD)是一种神经系统、自身免疫、脱髓鞘疾病。临床表型在成人和儿童之间存在差异,与成人人群相比,MOGAD在儿科人群中更为常见。文献中很少报道孤立性脑神经麻痹作为MOGAD的初始临床表型。在这里,我们报告了一个儿童,他表现为孤立的左第六脑神经麻痹,作为抗髓鞘少突胶质细胞糖蛋白抗体相关疾病(MOGAD)的初始症状。方法:在这个案例研究中,我们报告了一个三岁的女性已知的矫正和儿科眼科服务,由于间歇性外斜视。该患儿后来出现左眼急性会聚性偏视,并伴有病毒性疾病,无其他全身性症状。本病例报告了5年的临床表现和治疗。结果:免疫检查显示脑脊液中寡克隆带阳性,血清中阴性。血清MOG抗体阳性。磁共振成像(MRI)显示脑桥和小脑急性脱髓鞘,伴双侧脑白质病变,伴带状异位。症状性病变是左侧脑桥下部左侧第六脑神经固有路线上的一个小斑块,提示急性脱髓鞘。患者完成5天静脉注射甲基强的松龙30 mg/kg /天,随后口服强的松龙减量疗程。后续讨论:尽管在MOGAD中脑干受累是常见的,但孤立性脑瘫是罕见的,通常不报道儿童出现症状(Barr et al., 2000)。MOG抗体阳性的患者预后相对较好。在这里,我们强调在孤立性脑神经麻痹的鉴别诊断中考虑MOGAD的重要性,特别是在儿科人群中。
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引用次数: 0
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British and Irish Orthoptic Journal
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