Bikash Sahoo, Takahiro Watanabe-Nakayama, Saba Suladze, G. M. Anantharamaiah, Bernd Reif, Ayyalusamy Ramamoorthy
Nanodiscs are emerging as valuable tools for studying lipid-protein interactions. In this study, we demonstrate the dual role of nanodiscs in modulating human amylin (hIAPP) fibrillation using NMR and HS-AFM. Peptide-based nanodiscs promote hIAPP fibrillation, while polymer-nanodiscs inhibit aggregation. These findings broaden the applications of nanodiscs beyond structural studies.
{"title":"Bifunctional Nanodisc Platforms for Studies on Self-Assembly and Amyloid Fibrillation","authors":"Bikash Sahoo, Takahiro Watanabe-Nakayama, Saba Suladze, G. M. Anantharamaiah, Bernd Reif, Ayyalusamy Ramamoorthy","doi":"10.1039/d5cc00972c","DOIUrl":"https://doi.org/10.1039/d5cc00972c","url":null,"abstract":"Nanodiscs are emerging as valuable tools for studying lipid-protein interactions. In this study, we demonstrate the dual role of nanodiscs in modulating human amylin (hIAPP) fibrillation using NMR and HS-AFM. Peptide-based nanodiscs promote hIAPP fibrillation, while polymer-nanodiscs inhibit aggregation. These findings broaden the applications of nanodiscs beyond structural studies.","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"149 1","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minseok Ko, Mrinal Kanti Kabiraz, Yuseong Heo, Daehee Yang, Yeongseop Lee, Sang Hoon Joo, Young-Min Kim, Sang-Il Choi, Won Seok Seo
Here, we report the synthesis of ternary PtNiCo octahedral skeletal catalyst for the oxygen reduction reaction (ORR). A mixed flow of H2 and CO facilitated complete reduction, promoted Pt diffusion, and enabled the formation of octahedral PtNiCo nanoparticles (NPs). The resulting ternary skeletal catalyst, obtained after acid treatment, exhibited a mass activity (MA) of 1.64 A mgPt-1 and a specific activity (SA) of 3.73 mA cm-2, which are 7.5 and 14.3 times higher, respectively, than those of commercial Pt/C.
本文报道了用于氧还原反应（ORR）的三元PtNiCo八面体骨架催化剂的合成。H2和CO的混合流动有助于完全还原，促进Pt的扩散，并使八面体PtNiCo纳米颗粒（NPs）的形成成为可能。经酸处理得到的三元骨架催化剂的质量活性（MA）为1.64 a mgPt-1，比活性（SA）为3.73 MA cm-2，分别是商品Pt/C的7.5倍和14.3倍。
{"title":"Synthesis and Characterization of Ultra-Small Octahedral PtNiCo Skeletons with High Activity for Oxygen Reduction Reaction","authors":"Minseok Ko, Mrinal Kanti Kabiraz, Yuseong Heo, Daehee Yang, Yeongseop Lee, Sang Hoon Joo, Young-Min Kim, Sang-Il Choi, Won Seok Seo","doi":"10.1039/d5cc01349f","DOIUrl":"https://doi.org/10.1039/d5cc01349f","url":null,"abstract":"Here, we report the synthesis of ternary PtNiCo octahedral skeletal catalyst for the oxygen reduction reaction (ORR). A mixed flow of H<small><sub>2</sub></small> and CO facilitated complete reduction, promoted Pt diffusion, and enabled the formation of octahedral PtNiCo nanoparticles (NPs). The resulting ternary skeletal catalyst, obtained after acid treatment, exhibited a mass activity (MA) of 1.64 A mg<small><sub>Pt</sub></small><small><sup>-1</sup></small> and a specific activity (SA) of 3.73 mA cm<small><sup>-2</sup></small>, which are 7.5 and 14.3 times higher, respectively, than those of commercial Pt/C.","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"7 1","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hang Zhao, Hao Song, Zhefei Pan, Xun Zhu, Dingding Ye, Yang Yang, Hong Wang, Qiang Liao, Rong Chen
A twin Cu0.3Zn0.7S solid solution is developed for carbon dioxide photocatalytic reduction, in which ordered stacking faults induce homojunctions to enhance the separation and migration of photogenerated charge carriers. The high-coverage of *CO intermediate is responsible for promoting C-C coupling. The developed photocatalyst exhibits efficient CO2-to-C2H4 conversion with a C2H4 production rate of 8.45 μmol g-1 h-1 and an electron selectivity of 53.6%.
{"title":"Engineering Twin Cu0.3Zn0.7S for CO2 Photocatalytic Reduction to Ethylene","authors":"Hang Zhao, Hao Song, Zhefei Pan, Xun Zhu, Dingding Ye, Yang Yang, Hong Wang, Qiang Liao, Rong Chen","doi":"10.1039/d5cc02418h","DOIUrl":"https://doi.org/10.1039/d5cc02418h","url":null,"abstract":"A twin Cu0.3Zn0.7S solid solution is developed for carbon dioxide photocatalytic reduction, in which ordered stacking faults induce homojunctions to enhance the separation and migration of photogenerated charge carriers. The high-coverage of *CO intermediate is responsible for promoting C-C coupling. The developed photocatalyst exhibits efficient CO2-to-C2H4 conversion with a C2H4 production rate of 8.45 μmol g-1 h-1 and an electron selectivity of 53.6%.","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"9 1","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Electric-field-directed self-assembly enables unidirectional monolayer junction formation on gold substrate via terminal asymmetric Au–S and Au–C contacts, yielding stable rectifiers with defined polarity and diode I–V characteristics. This strategy defines a programmable method enabling the realization of uniform molecular-scale electronic devices through self-assembly.
{"title":"Electric-field-promoted assembly of asymmetric junctions for single-molecule rectifiers","authors":"Yaqi Zhang, Yaxuan Zhang, Ting Pan, Ping Zhou, Hongliang Chen","doi":"10.1039/d5cc02811f","DOIUrl":"https://doi.org/10.1039/d5cc02811f","url":null,"abstract":"Electric-field-directed self-assembly enables unidirectional monolayer junction formation on gold substrate via terminal asymmetric Au–S and Au–C contacts, yielding stable rectifiers with defined polarity and diode I–V characteristics. This strategy defines a programmable method enabling the realization of uniform molecular-scale electronic devices through self-assembly.","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"2 1","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Photo-catalyzed reduction of arylsulfonyl and benzoyl azides，which could be served as temporary masking group for amides, was achieved to access primary sulfonamides and benzoyl amides in mild conditions using organic reductant. A wide range of structurally diverse arylsulfonamides and benzoyl amides were accessed using this protocol in good yields. The mechanistic pathway of this reaction might generate the key amidyl radical through single electron transfer (SET).
{"title":"Visible-Light-Enabled Reduction of Arylsulfonyl and Benzoyl Azides to Access Primary Aryl sulfonamides and Benzoyl Amides","authors":"Qing Li, Xiaoxu Ma, Yue Bi, Mengxue Ma, Zhang Ping, Xianwei Sui","doi":"10.1039/d5cc02400e","DOIUrl":"https://doi.org/10.1039/d5cc02400e","url":null,"abstract":"Photo-catalyzed reduction of arylsulfonyl and benzoyl azides，which could be served as temporary masking group for amides, was achieved to access primary sulfonamides and benzoyl amides in mild conditions using organic reductant. A wide range of structurally diverse arylsulfonamides and benzoyl amides were accessed using this protocol in good yields. The mechanistic pathway of this reaction might generate the key amidyl radical through single electron transfer (SET).","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"8 1","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Despite relevance to metalloenzyme active-sites, the selective synthesis of heterobimetallic compounds featuring unbiased, biologically relevant coordination environments remains a challenge. Herein, we disclose a stepwise synthetic strategy, leveraging kinetic stabilization by an alkali metal cation, as a means of accessing spectroscopically pure M(II)/Ni(II) (M = Co & Cu) bimetallics. Electron paramagnetic resonance spectroscopy, variable temperature magnetrometry, and DFT calculations support perturbation of the electronic structure as a function of the heterometal within these closely related complexes.
尽管与金属酶活性位点相关，但具有无偏、生物相关配位环境的杂双金属化合物的选择性合成仍然是一个挑战。在此，我们公开了一种逐步合成策略，利用碱金属阳离子的动力学稳定，作为获得光谱纯M(II)/Ni(II) (M = Co &；铜双金属。电子顺磁共振光谱、变温磁强计和DFT计算支持电子结构的扰动，作为这些密切相关配合物中异质金属的函数。
{"title":"Synthesis and Electronic Structure Elucidation of Bioinspired Heterobimetallic Nickel Complexes","authors":"Claire R. Patterson, Paul Oyala, Joshua A. Buss","doi":"10.1039/d5cc03435c","DOIUrl":"https://doi.org/10.1039/d5cc03435c","url":null,"abstract":"Despite relevance to metalloenzyme active-sites, the selective synthesis of heterobimetallic compounds featuring unbiased, biologically relevant coordination environments remains a challenge. Herein, we disclose a stepwise synthetic strategy, leveraging kinetic stabilization by an alkali metal cation, as a means of accessing spectroscopically pure M(II)/Ni(II) (M = Co & Cu) bimetallics. Electron paramagnetic resonance spectroscopy, variable temperature magnetrometry, and DFT calculations support perturbation of the electronic structure as a function of the heterometal within these closely related complexes.","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"31 1","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iron hexacyanoruthenate, a Prussian blue analogue, was employed as a precursor to load highly dispersed Fe and Ru dual cocatalysts on an oxyiodide Ba2Bi3Nb2O11I, resulting in significantly enhanced activity for non-sacrificial O2 evolution with Fe3+ electron acceptor under visible light.
{"title":"Highly dispersed Fe-Ru dual cocatalyst derived from Prussian blue analogue for boosting O2 evolution on an oxyiodide photocatalyst","authors":"Reiya Takahashi, Hajime Suzuki, Harutaka Ninomiya, Makoto Ogawa, Osamu Tomita, Akinobu Nakada, Shunsuke Nozawa, Akinori Saeki, Ryu Abe","doi":"10.1039/d5cc02610e","DOIUrl":"https://doi.org/10.1039/d5cc02610e","url":null,"abstract":"Iron hexacyanoruthenate, a Prussian blue analogue, was employed as a precursor to load highly dispersed Fe and Ru dual cocatalysts on an oxyiodide Ba<small><sub>2</sub></small>Bi<small><sub>3</sub></small>Nb<small><sub>2</sub></small>O<small><sub>11</sub></small>I, resulting in significantly enhanced activity for non-sacrificial O<small><sub>2</sub></small> evolution with Fe<small><sup>3+</sup></small> electron acceptor under visible light.","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"196 1","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144568933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joana Oliveira, João T. S. Coimbra, Peiqing Yang, V. De Freitas, Nuno Basilio, Fernando Pina
A comparison of the thermodynamics and kinetics of two triacylated anthocyanins, pigment 1 from Clitoria ternatea (blue pea) and pigment 2 from Ipomoea tricolor (morning glory) reveals that, beyond the number of acylated units, the position of the sugar residues plays a crucial role in their stability.
{"title":"Achieving a Dramatic Blue Colour Stability in Anthocyanins Bearing Acylated Sugars in Position 3’,5’.","authors":"Joana Oliveira, João T. S. Coimbra, Peiqing Yang, V. De Freitas, Nuno Basilio, Fernando Pina","doi":"10.1039/d5cc03251b","DOIUrl":"https://doi.org/10.1039/d5cc03251b","url":null,"abstract":"A comparison of the thermodynamics and kinetics of two triacylated anthocyanins, pigment 1 from Clitoria ternatea (blue pea) and pigment 2 from Ipomoea tricolor (morning glory) reveals that, beyond the number of acylated units, the position of the sugar residues plays a crucial role in their stability.","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"189 1","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vavilapalli Suresh, T. Mahipal Reddy, Jagadeesh Babu Nanubolu, Sridhar Reddy Maddi
Harnessing and controlling the metal catalyzed cascade cyclizations constitutes a challenging task but offers an outstanding tool to access polycyclic scaffolds. We present herein a Pd(II)-catalyzed cascade cyclization of 1,8-diyne oxime ethers via a consecutive intramolecular oxy-palladation/carbopalladation/ C−H annulation for the construction of oxepine fused trinuclear polycyclic scaffolds. Some control and kinetic experiments were carried out to understand the mechanism, and few product elaborations were achieved to further showcase the potential of the reaction.
{"title":"Pd-Catalyzed Electrophilic Cyclization/C−H Annulation Cascade of 1,8-Diyne Oxime Ethers to Access Fused Oxepines","authors":"Vavilapalli Suresh, T. Mahipal Reddy, Jagadeesh Babu Nanubolu, Sridhar Reddy Maddi","doi":"10.1039/d5cc03700j","DOIUrl":"https://doi.org/10.1039/d5cc03700j","url":null,"abstract":"Harnessing and controlling the metal catalyzed cascade cyclizations constitutes a challenging task but offers an outstanding tool to access polycyclic scaffolds. We present herein a Pd(II)-catalyzed cascade cyclization of 1,8-diyne oxime ethers via a consecutive intramolecular oxy-palladation/carbopalladation/ C−H annulation for the construction of oxepine fused trinuclear polycyclic scaffolds. Some control and kinetic experiments were carried out to understand the mechanism, and few product elaborations were achieved to further showcase the potential of the reaction.","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"41 1","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144569019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A direct single-step catalytic asymmetric synthesis of [2.2]paracyclophanes (PCPs) bearing both planar and central chirality is reported via photocobalt-catalyzed desymmetrization. This reaction proceeds efficiently under mild conditions and exbihts broad functional group tolerance with high stereoselectivities, thus providing a platform for the synthesis of valuable multi-chiral PCPs.
{"title":"Catalytic Asymmetric Construction of Planarly and Centrally Chiral [2.2]paracyclophanes by Merging Photochemical and Cobalt Catalyzed Desymmetrization","authors":"Ke-Feng Zhang, Lin-Hui Zhou, Yan-Xi Chen, Wei-Wei Chen, Yuan-Mei Feng, Fang Ma","doi":"10.1039/d5cc03310a","DOIUrl":"https://doi.org/10.1039/d5cc03310a","url":null,"abstract":"A direct single-step catalytic asymmetric synthesis of [2.2]paracyclophanes (PCPs) bearing both planar and central chirality is reported via photocobalt-catalyzed desymmetrization. This reaction proceeds efficiently under mild conditions and exbihts broad functional group tolerance with high stereoselectivities, thus providing a platform for the synthesis of valuable multi-chiral PCPs.","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"197 1","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144569023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：