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An Event based Body Coupled Transdural Telemetry for Intracortical Brain Computer Interfaces. 基于事件的体耦合经硬脑膜遥测皮层内脑机接口。
IF 7 Pub Date : 2026-09-01 DOI: 10.1038/s44172-026-00735-z
Chengyao Shi, Laura Nuttin, Zhenyu Gao, Yuming He, Pietro Russo, Hua-Peng Liaw, Marios Gourdouparis, Dennis Lambrechts, Guido Dolmans, Yao-Hong Liu

Intracortical brain-computer interfaces (iBCIs) hold promise for restoring motor, sensory, and cognitive functions, including applications in paralysis treatment and speech decoding. High-density microelectrode arrays (MEAs) provide fine spatial and temporal discrimination of neural activity, but the considerable upsurge in data generation poses challenges for wireless transmission from miniaturized implants due to constraints on power, bandwidth, heat dissipation, and device size. To address these constraints, we propose a two-stage wireless iBCI architecture comprising a transdural galvanic-coupled body channel communication (BCC) link from a free-floating MEA to an intracranial unit, followed by a transcutaneous link to an external unit. This study focuses on the transdural BCC telemetry system, which provides compact, wideband, and energy-efficient data transmission. Phantom tests, and ex vivo experiments using a human cadaveric head specimen validate the system, demonstrating wireless transmission up to 500 Mbps with 20% duty cycling and bit error rates below 10⁻⁵. The system incorporates the send-on-delta encoder (SODA), achieving up to 11.4× data compression and reducing thermal load for meeting the safety guidelines. Safety is further examined using brain-on-a-chip models, which demonstrate that the system does not evoke unintended neural activity, supporting the platform's long-term viability for high-resolution iBCIs.

皮质内脑机接口(ibci)有望恢复运动、感觉和认知功能,包括在瘫痪治疗和语音解码中的应用。高密度微电极阵列(MEAs)提供了精细的神经活动空间和时间识别,但由于功率、带宽、散热和设备尺寸的限制,数据生成的大量增加给小型化植入物的无线传输带来了挑战。为了解决这些限制,我们提出了一种两阶段无线iBCI架构,包括从自由浮动MEA到颅内单元的经硬膜电偶体通道通信(BCC)链路,然后经皮连接到外部单元。本研究的重点是跨硬膜BCC遥测系统,它提供了紧凑、宽带和节能的数据传输。幻影测试和使用人类尸体头部样本的离体实验验证了该系统,证明无线传输速度高达500mbps,占空比为20%,误码率低于10。该系统集成了增量上发送编码器(SODA),实现了高达11.4倍的数据压缩,并降低了热负荷,以满足安全准则。使用脑芯片模型进一步检查了安全性,结果表明该系统不会引起意外的神经活动,支持该平台用于高分辨率ibci的长期可行性。
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引用次数: 0
Porous-lift-off germanium membranes as lightweight, flexible, and cost-effective template for III-V space solar cells: a review. 作为III-V型空间太阳能电池的轻量化、柔性和高性价比模板的多孔锗膜:综述
IF 7 Pub Date : 2026-08-25 DOI: 10.1038/s44172-026-00759-5
Azmat Ali, Radouane En-Nadir, Chahinaz Khouloud Mahboub, Imad-Eddine Mokeddem, Ahmed Ayari, Brieuc Mével, Jérôme Ripa, Artur Turala, Alexandre Chapotot, Priyanka Proost, Rajiv Sharma, Jinyoun Cho, Kristof Dessein, Abderraouf Boucherif

The growing demand for low-cost, lightweight, and high-efficiency space technologies has driven the search for photovoltaic solutions which minimize material use without sacrificing performance. III-V multijunction solar cells remain the state of the art for space power applications due to their exceptional efficiency and radiation resistance. Among III-V solar cells architectures, Germanium (Ge)-based structure remains widely used; however, their broader deployment is limited by reliance on thick and expensive Ge substrates. Germanium membranes, however, offer a promising path to address these limitations through substrate reuse strategies. This review highlights progress in the development of Ge membrane as a transformative platform for space photovoltaics, with a focus on porous Ge-based lift-off approaches while reusing Ge substrate. These methods enable the fabrication of detachable, monocrystalline Ge membrane through pore etching, epitaxial growth, porous transformation, layer lift-off and substrate reuse, significantly reducing Ge consumption and device weight. Two main fabrication routes for porous Ge formation are discussed: lithography-based dry etching using Ge-On-Nothing approach and electrochemical etching. The fundamentals of pore formation, thermal reorganization of porous, and subsequent III-V epitaxy are reviewed. Key challenges related to process uniformity, detachment scalability, and industrial integration are examined, and potential strategies for scalable manufacturing are outlined.

对低成本、轻量化和高效率空间技术的需求不断增长,促使人们寻找在不牺牲性能的情况下最小化材料使用的光伏解决方案。III-V型多结太阳能电池由于其卓越的效率和抗辐射性,在空间电源应用中仍然是最先进的。在III-V型太阳能电池结构中,锗基结构仍被广泛使用;然而,由于依赖于厚而昂贵的Ge基板,它们的广泛部署受到限制。然而,锗膜通过衬底再利用策略提供了解决这些限制的有希望的途径。这篇综述强调了锗膜作为空间光伏发电变革平台的发展进展,重点是在重复使用锗衬底的同时,基于多孔锗的升空方法。这些方法可以通过孔刻蚀、外延生长、多孔转变、层剥离和衬底再利用来制造可拆卸的单晶锗膜,显著降低锗消耗和器件重量。讨论了制备多孔锗的两种主要工艺路线:基于光刻技术的无晶锗法干法蚀刻和电化学蚀刻。综述了孔的形成、孔的热重组和随后的III-V外延的基本原理。研究了与工艺一致性、分离可扩展性和工业集成相关的关键挑战,并概述了可扩展制造的潜在策略。
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引用次数: 0
Mechanics-informed risk-aware learning for multiaxial structural reliability with Bayesian calibration. 基于贝叶斯校准的多轴结构可靠性力学风险意识学习。
IF 7 Pub Date : 2026-08-14 DOI: 10.1038/s44172-026-00752-y
Gaofeng Zhang, Xuanrui Yu, Anxiang Song, Hanguang Liu, Xinhong Lin, Xuyijin Zhang, Qianling Wang, Wentao Wang, Pandeng Zhang

Reliable prediction of structural vulnerability under complex multiaxial loading remains challenging due to nonlinear load couplings, imbalanced failure-critical samples, and limited model interpretability. Here, we present a mechanics-informed, risk-aware learning framework integrating polynomial-harmonic feature augmentation, Weibull-based risk reweighting, and a unified Degradation Risk Score that combines stress margins and bolt pretension loss. Demonstrated on a bolted steering-knuckle assembly with finite-element-derived multiaxial load-response data, the framework improves multiple linear regression from R² = 0.37 to 0.96 with a 67% reduction in RMSE, while enhancing robustness and sensitivity in high-risk regimes across ensemble and neural network models. SHAP analysis confirms that physically meaningful multiaxial interaction features dominate predictions, revealing critical load paths associated with structural vulnerability. Finally, Bayesian logistic and Weibull calibration provide a route to link Degradation Risk Score to component-level failure probabilities, enabling probabilistic risk assessment and reliability-centred decision-making in practical engineering systems.

由于非线性载荷耦合、失效临界样本不平衡和模型可解释性有限,复杂多轴载荷下结构易损性的可靠预测仍然具有挑战性。在这里,我们提出了一个力学信息,风险意识的学习框架,集成了多项式调和特征增强,基于weibull的风险重加权,以及统一的退化风险评分,结合了应力裕度和螺栓预紧损失。该框架在螺栓转向节组件上进行了演示,并使用有限元衍生的多轴载荷响应数据进行了验证,结果表明,该框架改进了从R²= 0.37到0.96的多元线性回归,RMSE降低了67%,同时增强了集成模型和神经网络模型在高风险体系中的鲁棒性和灵敏度。SHAP分析证实,物理上有意义的多轴相互作用特征主导了预测,揭示了与结构脆弱性相关的关键载荷路径。最后,贝叶斯逻辑和威布尔校准提供了一条将退化风险评分与部件级故障概率联系起来的途径,从而在实际工程系统中实现概率风险评估和以可靠性为中心的决策。
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引用次数: 0
Equal access in urban spaces: Gendered perspectives and actions for greater equity. 城市空间的平等准入:性别视角和促进平等的行动。
IF 7 Pub Date : 2026-08-14 DOI: 10.1038/s44172-026-00753-x
Natasha Watson
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引用次数: 0
Four years on: following the pathway to real world impact of engineering research. 四年来:跟随工程研究走向现实世界的影响。
IF 7 Pub Date : 2026-07-31 DOI: 10.1038/s44172-026-00743-z
Michele Polese, Josep M Jornet, Lorne Hofstetter, Omid Yaghmazadeh, Goran Goranović, Jan Kloppenborg Møller, Amira Abdel-Rahman
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引用次数: 0
Impact in engineering research: more than a number. 对工程研究的影响:不止一个数字。
IF 7 Pub Date : 2026-07-31 DOI: 10.1038/s44172-026-00744-y
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引用次数: 0
Millisecond magnetic particle imaging of a cerebral aneurysm phantom with and without flow diverter stent. 颅内动脉瘤幻像伴及不伴分流支架的毫秒磁粉成像。
IF 7 Pub Date : 2026-07-29 DOI: 10.1038/s44172-026-00726-0
Olaf Kosch, Augusto Fava Sanches, Yigit Özpeynirci, Thomas Liebig, Frank Wiekhorst

Undetected, asymptomatic brain aneurysms are associated with risk of progressive expansion, followed by rupture and hemorrhage, increasing the risk of mortality and morbidity. Imaging techniques to assess the state and stent treatment of aneurysms are beneficial. By Magnetic Particle Imaging (MPI), we were able to resolve with millisecond temporal resolution the location and movement of a tracer bolus in different parts of an artery phantom derived from a patient specific CT data set including a cerebral aneurysm. To assess the success of a flow diverter stent treatment, we compared flow MPI measurements in the artery phantom without a flow diverter stent with images where a stent was inserted. Our results provide valuable information on the capabilities and prospects of MPI of vascular structures and the detection and quantification of flow changes in untreated and treated aneurysms for future in vivo applications.

未被发现的无症状脑动脉瘤具有进行性扩张、破裂和出血的风险,增加了死亡率和发病率的风险。影像学技术评估动脉瘤的状态和支架治疗是有益的。通过磁颗粒成像(MPI),我们能够以毫秒级的时间分辨率分辨出示踪剂丸在动脉幻像不同部位的位置和运动,这些数据来自患者特定的CT数据集,包括脑动脉瘤。为了评估分流支架治疗的成功,我们比较了没有分流支架的动脉幻影中的血流MPI测量值与置入支架的图像。我们的结果为血管结构的MPI的能力和前景以及未治疗和治疗动脉瘤的血流变化的检测和量化提供了有价值的信息,为未来的体内应用提供了参考。
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引用次数: 0
Self-deploying reinforced concrete structures. 自展钢筋混凝土结构。
IF 7 Pub Date : 2026-07-23 DOI: 10.1038/s44172-026-00725-1
Ezra Ben-Abu, Anna Zigelman, Hod Lipson, Amir D Gat

Formwork for concrete construction remains one of the most resource-intensive, polluting, and constraining components of the construction sector, relying on prefabricated molds that demand extensive material, labor, and on-site preparation. We introduce a self-deploying formwork system based on multistable tubes that transform from a compact configuration to a full-scale structural mold with integrated steel reinforcement. We demonstrate this concept by deploying a steel-reinforced 2.36 m high structure within 14 seconds. We further observed that the polymer shell of the multistable tubes increases the structural strength by a factor of three, significantly enhancing their load-bearing capacity. The demonstrated concept paves the way for the creation of concrete castings with minimal on-site intervention, enabling a scalable pathway toward rapid, low-carbon construction methods.

混凝土施工模板仍然是建筑部门中资源最密集、污染最严重、限制最严格的部件之一,它依赖于预制模具,需要大量的材料、劳动力和现场准备。我们介绍了一种基于多稳定管的自部署模板系统,该系统从紧凑的配置转变为具有集成钢加固的全尺寸结构模具。我们通过在14秒内部署2.36米高的钢筋结构来展示这一概念。我们进一步观察到,多稳定管的聚合物外壳将结构强度提高了三倍,显著提高了其承载能力。所展示的概念为混凝土铸件的创造铺平了道路,减少了现场干预,实现了快速、低碳施工方法的可扩展路径。
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引用次数: 0
A bulk acoustic resonator with vertical electrodes for wideband filters. 带垂直电极的体声谐振器,用于宽带滤波器。
IF 7 Pub Date : 2026-07-21 DOI: 10.1038/s44172-026-00733-1
Silvan Stettler, Edgar Navarro-Gessé, Carlos Collado, Jordi Mateu, Luis Guillermo Villanueva

Radiofrequency front ends for current and next generation (5G and 6G) wireless communication demand acoustic filters that combine wide bandwidth, high power capability, and thermal stability. Existing surface and bulk acoustic wave technologies face inherent trade-offs between electromechanical coupling, lithographic tunability, and robustness. Here, we introduce the bulk acoustic resonator with vertical electrodes (VBAR), a device that combines the advantages of suspended and solidly mounted resonators. VBARs use lithium niobate ridges with sidewall electrodes to excite a shear-horizontal bulk acoustic resonance, providing frequency control through lithography in a configuration that is mechanically anchored to the substrate. Fabricated VBARs exhibit electromechanical coupling coefficients exceeding 30% in the 2-4 GHz range, enabling ladder filters with fractional bandwidths of nearly 20%. While further optimization is necessary to minimize losses, the VBAR concept offers an alternative route toward wideband and robust radiofrequency filters for next-generation wireless systems.

当前和下一代(5G和6G)无线通信的射频前端需要结合宽带、高功率和热稳定性的声学滤波器。现有的表面和体声波技术面临着机电耦合、光刻可调性和鲁棒性之间的内在权衡。在这里,我们介绍了垂直电极体声谐振器(VBAR),它结合了悬浮谐振器和固体谐振器的优点。vbar使用带有侧壁电极的铌酸锂脊来激发剪切水平体声共振,通过光刻技术提供频率控制,该结构机械固定在基板上。制造的vbar在2-4 GHz范围内的机电耦合系数超过30%,使阶梯式滤波器的分数带宽接近20%。虽然需要进一步优化以最小化损耗,但VBAR概念为下一代无线系统提供了通往宽带和鲁棒射频滤波器的替代途径。
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引用次数: 0
High-throughput super-resolution imaging chip based on miniaturized full-frequency encoded-illumination. 基于小型化全频编码照明的高通量超分辨率成像芯片。
IF 7 Pub Date : 2026-07-21 DOI: 10.1038/s44172-026-00722-4
Xiaoyu Yang, Haonan Zhang, Yuqi Zhang, Feihong Lin, Mingwei Tang, Tawfique Hasan, Clemens F Kaminski, Xu Liu, Qing Yang

Super-resolution microscopy has become an indispensable core research tool in biology, materials science and medicine, yet existing technologies face an inherent bottleneck where resolution, large field of view (FOV), label-free compatibility and system cost cannot be simultaneously optimized. A miniaturized full-frequency encoded illumination (mini-FEI) chip is presented for high-throughput super-resolution imaging using the spatial frequency shift (SFS) effect. We propose a tunable continuous SFS method for across far-field and near-field illumination modulation, which is achieved through propagating and evanescent waves. The multi-illumination modes are precisely and flexibly modulated by an encoded LED array. The light travels to the sample via a set of prisms, producing super-resolution images with high signal-to-noise ratio (SNR). Mini-FEI super-resolution imaging reaches a resolution of 333 nm ( ~ λ/4NA), while maintaining a large FOV of ~1 mm2. The method is validated on label-free samples including USAF Target, Star Target, onion root tip cells, and live COS7 cells, all of which could be successfully reconstructed. Through the introduction of integrated LED arrays for evanescent wave excitation, expensive laser systems can be avoided and the system significantly miniaturized. The mini-FEI super-resolution imaging chip is simple and cost-effective to fabricate, is compatible with commercial microscopes, and thus holds great potential for widespread deployment in scientific and industrial research.

超分辨率显微镜已成为生物学、材料科学和医学领域不可或缺的核心研究工具,但现有技术面临分辨率、大视场(FOV)、无标签兼容性和系统成本无法同时优化的固有瓶颈。提出了一种利用空间频移(SFS)效应实现高通量超分辨率成像的小型化全频编码照明(mini-FEI)芯片。我们提出了一种可调谐的跨远场和近场照明调制的连续SFS方法,该方法通过传播波和倏逝波来实现。通过编码LED阵列精确灵活地调制多种照明模式。光通过一组棱镜到达样品,产生具有高信噪比(SNR)的超分辨率图像。Mini-FEI超分辨率成像达到了333 nm (~ λ/4NA)的分辨率,同时保持了~1 mm2的大视场。该方法在USAF靶细胞、Star靶细胞、洋葱根尖细胞、COS7活细胞等无标记样品上进行了验证,均可成功重建。通过引入集成LED阵列进行倏逝波激发,可以避免昂贵的激光系统,并使系统显着小型化。mini-FEI超分辨率成像芯片制造简单,成本效益高,与商用显微镜兼容,因此在科学和工业研究中具有广泛应用的巨大潜力。
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引用次数: 0
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Communications engineering
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