Navigating the landscape of EGFR TKI resistance in EGFR-mutant NSCLC — mechanisms and evolving treatment approaches

已完结 10 由小周发布于 2026/5/15 23:07:44

DOI:10.1038/s41571-025-01085-z
作者：Jing Zhao,?Wanting Xu,?Fei Zhou,?Xiangyu Zhang,?Mo Zhou,?Da Miao,?Lan Yu,?Yongchang Zhang,?Junqiang Fan,?Caicun Zhou,?Wen Li,?Tony Mok,?Xiuning Le,?Molly Li,?Yang Xia
文献类型：期刊论文
补充材料：只需要正文

Nature

Abstract：Resistance to EGFR tyrosine kinase inhibitors (TKIs) remains a major obstacle in the clinical management of EGFR-mutant non-small-cell lung cancer (NSCLC). Despite the transformative therape

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