Synthetic Development and Scale-Up of a Complex Pyrazole Fragment of Lenacapavir

已完结 10 由北菜的豆发布于 2024/8/5 21:45:56

DOI:10.1021/acs.oprd.4c00235
作者：Nathaniel Kadunce, Olivier St-Jean, Amy Cagulada, Wen-Tau T. Chang, Alexander F. G. Goldberg, Zilin Huang, Jihun Kang, Jinsik Kim, Kyoungchan Kwon, Olga Lapina, Lennie Lin, Trevor J. Rainey, Lyubov Roever, Nisha P. Shah, Scott A. Wolckenhauer
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：We describe herein the process development and scale-up of a complex cyclopropyl pyrazole fragment of lenacapavir, a drug recently approved for long-acting treatment of HIV (Sunlenca). A ten

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