Targeting N-Myc in neuroblastoma with selective Aurora kinase A degraders

已完结 10 由 Luke 发布于 2025/6/17 22:10:06

DOI:10.1016/j.chembiol.2024.12.006
作者：Jian Tang ,?Ramkumar Moorthy ,?Laura E. Hirsch ,??zlem Demir ,?Zachary D. Baker ,?Jordan A. Naumann ,?Katherine F.M. Jones ,?Michael J. Grillo ,?Ella S. Haefner ,?Ke Shi ,?Michaella J. Levy ,?Harshita
文献类型：期刊论文
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Elsevier

Abstract：The N-Myc transcription factor, encoded by MYCN, is a mechanistically validated, yet challenging, target for neuroblastoma (NB) therapy development. In normal neuronal progenitors, N-Myc und

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