Mutant KRAS peptide targeted CAR-T cells engineered for cancer therapy

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DOI:10.1016/j.ccell.2025.05.006
作者：Alexander Benton, Jiageng Liu, Mathilde A. Poussin, Andrea Lang Goldgewicht, Madhara Udawela, Adham S. Bear, Nils Wellhausen, Beatriz M. Carreno, Pete M. Smith, Matthew D. Beasley, Ben R. Kiefel, Dani
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Elsevier

Abstract：Despite the success of chimeric antigen receptor (CAR)-T cell therapies in hematological malignancies, clinical success against solid tumors is limited due to low therapeutic efficacy or dos

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