Elucidating lipid nanoparticle properties and structure through biophysical analyses.

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DOI:10.1038/s41587-025-02855-x
作者：Marshall S Padilla,Sarah J Shepherd,Andrew R Hanna,Martin Kurnik,Xujun Zhang,Michelle Chen,James Byrnes,Ryann A Joseph,Hannah M Yamagata,Adele S Ricciardi,Kaitlin Mrksich,David Issadore,Kushol Gupta,M
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Nature

Abstract：Designing lipid nanoparticle (LNP) delivery systems with specific targeting, potency and minimal side effects is crucial for their clinical use. However, traditional characterization methods

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