Payload Diversification Overcomes Resistance and Guides Sequential Antibody-Drug Conjugate Therapy in Breast Cancer

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DOI:10.1158/1078-0432.ccr-25-3321
作者：Dileep Reddy. Rampa, Minji Seo, Nanae Ogata, Zhaoxuan Yang, Nithya Sridhar, Fujii Takeo, Chalothorn Wannaphut, Jennifer A. Maynard, Kyoji Tsuchikama, George W. Sledge, Naoto T. Ueno, Jangsoon Lee
文献类型：期刊论文
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American Association for Cancer Research (AACR)

Abstract：Purpose: Antibody–drug conjugates (ADCs) have transformed the treatment of breast cancer. FDA-approved ADCs such as trastuzumab deruxtecan (T-DXd), sacituzumab govitecan (SG), and datopotama

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