Nucleotide metabolic rewiring enables NLRP3 inflammasome hyperactivation in obesity

待确认 10 由东发布于 2026/1/30 17:40:07

DOI:10.1126/science.adq9006
作者：Danhui Liu,?Chuanli Zhou,?Xiaochen Wang,?Zhou Luo,?Ruiyao Xu,?Shanshan Huo,?Lina Guo,?Xuemei Luo,?Shuhan Yang,?Arielle Click,?Janiece Vancil,?Paola Barajas,?Victor Mijares,?Hamid Baniasadi,?Nan Yan,?J
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：Obesity is a major disease risk factor due to obesity-associated hyperinflammation. We found that obesity induced Nod-like receptor pyrin domain–containing 3 (NLRP3) inflammasome hyperactiva

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