Astrocytic LCN2 drives neuronal dysfunction in epilepsy by suppressing tunnel nanotube-mediated mitochondrial transfer via NLRP3 inflammasome activation

已完结 10 由 Unique 发布于 2025/12/16 14:51:52

DOI:10.1016/j.freeradbiomed.2025.11.061
作者：Zixian Zhou , Pengcheng Zhang , Yanlin Jiang , Yingchun Xu , Fangzhou Liu , Xinyu Chen , Deng Chen , Wenfu Tang , Rujia Liao , Ling Liu
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1016/j.freeradbiomed.2025.11.061

Elsevier

Abstract：Epileptic seizures disrupt brain homeostasis not only by directly challenging neuronal excitability but also by impairing the intricate astrocyte-neuron cross-talk essential for metabolic su

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