PreTKcat: A pre-trained representation learning and machine learning framework for predicting enzyme turnover number

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DOI:10.1016/j.compbiolchem.2024.108327
作者：Yunxiang Cai ,?Wenjuan Zhang ,?Zhuangzhuang Dou ,?Chao Wang ,?Wenping Yu ,?Lin Wang
文献类型：期刊论文
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Elsevier

Abstract：The enzyme turnover number (kcat) is crucial for understanding enzyme kinetics and optimizing biotechnological processes. However, experimentally measured kcat values are limited due to the

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