PARP1-mediated PARylation of TEAD4 stabilizes the YAP1-TEAD4 complex and promotes growth and immune evasion in breast cancer cells

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DOI:10.1126/scisignal.adx2532
作者：Yibo Guo,?Gaoqing Song,?Hailin Zou,?Liangxin Lu,?Xuyin Dai,?Chuannan Sun,?Haoming Chen,?Tongyu Tong,?Mengjun Huang,?Mengyuan Zhu,?Liang Deng,?Yulong He,?Changhua Zhang,?Juan Luo,?Peng Li
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：The transcriptional coactivator YAP1 regulates numerous biological processes, including organ size control and tissue homeostasis. Although its hyperactivity promotes tumor development and p

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