Transferrin receptor–targeted anti-amyloid antibody enhances brain delivery and mitigates ARIA

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DOI:10.1126/science.ads3204
作者：Michelle E. Pizzo, Edward D. Plowey, Nathalie Khoury, Wanda Kwan, Jordan Abettan, Sarah L. DeVos, Claire B. Discenza, Timothy Earr, David Joy, Ming Lye-Barthel, Elysia Roche, Darren Chan, Jason C. Dug
文献类型：期刊论文
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文献链接：https://doi.org/10.1126/science.ads3204

American Association for the Advancement of Science (AAAS)

Abstract：Amyloid-related imaging abnormalities (ARIA), side effects of anti-amyloid drugs seen in magnetic resonance imaging of the brain, are a major safety concern in patients with Alzheimer’s dise

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