Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds.

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DOI:10.1016/j.cell.2014.11.052
作者：Jesse G Zalatan,?Michael E Lee,?Ricardo Almeida,?Luke A Gilbert,?Evan H Whitehead,?Marie La Russa,?Jordan C Tsai,?Jonathan S Weissman,?John E Dueber,?Lei S Qi,?Wendell A Lim
文献类型：期刊论文
补充材料：仅需补充材料
文献链接：https://doi.org/10.1016/j.cell.2014.11.052

Elsevier

Abstract：Eukaryotic cells execute complex transcriptional programs in which specific loci throughout the genome are regulated in distinct ways by targeted regulatory assemblies. We have applied this

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