A tunable nanocomposite hydrogel based on carboxymethyl chitosan/chitooligosaccharide for on-demand tissue-targeted drug delivery in psoriasis treatment

待确认 20 由 Dorr 发布于 2026/6/11 21:47:40

DOI:10.1016/j.ijbiomac.2025.149782
作者：Shu Liang ,?Yunyi Zhang ,?Jiawei Lv ,?Zhangwen Peng ,?Zun Li ,?Wenyi Liao ,?Shenyu Li ,?Xiyuan Lai ,?Manna Guo ,?Yulu Zhou ,?Jin Liu ,?Yang Deng ,?Xiongjun Wang ,?Yufeng Ding ,?Chao Zhao ,?Lingyun Xia
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Abstract：While the enhanced permeability of psoriatic skin facilitates topical delivery, it also poses challenges in drug retention and systemic absorption. To address these limitations, we designed

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