Ultraprecision therapy for type 1 vs type 2 CALR+ MPN by dual epitope targeting that restores ruxolitinib sensitivity.

求助中 20 由凯月发布于 2026/6/10 9:43:25

DOI:10.1182/blood.2024027897
作者：Chloe A L Thompson-Peach,?Daniel Thomas,?Mara Dottore,?Kelly Lim,?Frank Stomski,?Romana A Panagopoulos,?Johannes Fo?elteder,?Andreas Reinisch,?Vashe Chandrakanthan,?Sandra Jenkner,?Luke Bland,?Sharon
文献类型：期刊论文
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American Society of Hematology (ASH)

Abstract：Abstract: Somatic frameshift mutations in the gene encoding calreticulin (CALR) give rise to myelofibrosis and are classified as type 1 (del52) or type 2 (ins5) according to the degree of wi

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