Carboxylic Acid Bioisosteres of Creatine as Novel and Selective Substrate Competitive Inhibitors of the Creatine Transporter SLC6A8

已完结 10 由陈丽伊发布于 2026/10/30 10:28:24

DOI:10.1021/acs.jmedchem.5c02607
作者：Eduardo J. Martinez*,?, ,?Darren H. Wong,?, ,?Amish J. Patel,?, ,?Roy J. Vaz,?, ,?Robert W. Busby,?, ,?Robert Zahler,?, ,?Daniel Schefer,?, ,?Hui Zhao,?, ,?Xiaoming Xu,?, ,?Zizhao Liu,?, ,?Ruifang Men
文献类型：期刊论文
补充材料：只需要正文

American Chemical Society (ACS)

Abstract：Creatine, a naturally occurring guanidine carboxylic acid, serves as a critical energy metabolite in tissues with high energy demands. Certain cancers upregulate creatine metabolism to suppl

应助信息

21小时前

biofresh

68c78d5fd40a11f193e4208810ba6e4f.pdf 已采纳

21小时前

Book学术机器人

2026/10/30 10:28:24 未找到该文献，机器人已退出，请等待人工下载

2026/10/30 10:28:24 Book学术AI机器人收到请求，开始寻找文献

2026/10/30 10:28:24 已向机器人发送请求

21小时前

陈丽伊发布求助

上一个求助:其它数据库Naturally Fractured Carbonate Reservoir Characterization: A Case Study of a Mature High-Pour Point Oil Field in Hungary 下一个求助:American Psychological Association (APA)Deconfounding the effects of dominance and social acceptance on self-esteem.