Mitochondrial Communications

Homoplasmic MT-TG m.9997T>C variant associated with hypertrophic cardiomyopathy: Pathogenicity and genotype–phenotype analysis

Pub Date : 2026-01-01 DOI: 10.1016/j.mitoco.2026.06.001 Jianing Wang, Jiayin Wang, Busu Li, Xiaojing Zhu, Yan Lin, Ying Zhao, Weiyue Si, Yuying Zhao, Chuanzhu Yan, Kunqian Ji

Advances in the role of mitochondrial homeostasis in hepatocellular carcinoma initiation and progression: Mechanisms and therapeutic opportunities

Pub Date : 2026-01-01 DOI: 10.1016/j.mitoco.2026.07.002 Jiashun Xu, Xinlei Meng, Ming Gong, Ensong Sun, Jianwei Sun, Hayam Hamdy, Junling Shen, Hui Li

Mitochondrial NMNAT3 reduces amyloid aggregates in Drosophila and alters the amyloid processing in the 3xTgAD mouse

Pub Date : 2026-01-01 DOI: 10.1016/j.mitoco.2026.01.001 Zhu Yi , Naynika Juvvadi , Grace Zhai , Carlos T. Moraes , Milena Pinto