Investigación Clínica

CircRNA_104293 targets miR-497-5p to inhibit the mTOR/STAT3 pathway and mitigate inflammation in Crohn’s disease.

Pub Date : 2025-12-09 DOI: 10.54817/ic.v66n4a02 Xuerui Yin, Gaigai Huang, C Zheng, Yu Zhou, Rong Chen

Rutin as a potential therapeutic agent for arsenic-induced testicular damage: Antioxidant, anti-inflammatory, and anti-apoptotic effects.

Pub Date : 2025-12-09 DOI: 10.54817/ic.v66n4a05 Yunyun Wang, Zengrong Hua, Jin Qing Hui, Dandan Qiu

Lycopene regulates the formation of calcium oxalate kidney stones by modulating reactive oxygen species(ROS) and NF-κB pathways.

Pub Date : 2025-06-07 DOI: 10.54817/ic.v66n2a07 Liangwen Ye, Yuhang Tang, Zhijie Zhang, Xiangyi Hou, Wei Xu, Xianghui Suo, Li Zhang