Biological and Pharmaceutical Bulletin

Enhancing Corneal Drug Penetration Using Penetratin for Ophthalmic Suspensions

Pub Date : 2024-05-25 DOI: 10.1248/bpb.b24-00077 Ryo Morofuji, Kazuhiro Kudo, Takahiro Honda, Shino Kinugasa, Takamasa Matsuo, Komei Okabe

Short-Term Preexposure to Novel Enriched Environment Augments Hippocampal Ripples in Urethane-Anesthetized Mice

Pub Date : 2024-05-24 DOI: 10.1248/bpb.b24-00118 Rio Okada, Yuji Ikegaya, Nobuyoshi Matsumoto

Modeled Hepatic/Plasma Exposures of Omeprazole Prescribed Alone in Cytochrome P450 2C19 Poor Metabolizers Are Likely Associated with Hepatic Toxicity Reported in a Japanese Adverse Event Database

Pub Date : 2024-05-24 DOI: 10.1248/bpb.b24-00145 K. Adachi, K. Ohyama, Yoichi Tanaka, N. Murayama, M. Shimizu, Yoshiro Saito, Hiroshi Yamazaki