Advances in cell and gene therapy

Serpin B9-Insensitive Granzyme B Mutant Delivered by Engineered Capsid AAV Vectors Demonstrates Selective Killing of EGFR-Positive Cancer Cells

Pub Date : 2025-06-13 DOI: 10.1155/acg2/8881294 Dennis Makafui Dogbey, Krupa Naran, Stefan Barth

Long-Term Correction of Murine Glycogen Storage Disease Type III by AAV-Mediated Gene Therapy Using an Immunotolerizing Dual Promoter to Express Bacterial Pullulanase

Pub Date : 2025-04-17 DOI: 10.1155/acg2/4639392 Kuo-An Liao, Jeong-A Lim, Su Jin Choi, Haiqing Yi, Baodong Sun

The Impact of Niacin Administration on Plasma Lipids and Gene Expression in the Vervet Monkey Model (Chlorocebus aethiops)

Pub Date : 2025-02-05 DOI: 10.1155/acg2/6679813 Thobile Ngqaneka, Zandisiwe Emilia Magwebu, Kenechukwu Obikeze, Chesa Gift Chauke