Effect of three different doses of oxytocin infusion on hemodynamic changes in cesarean delivery

Abstract

"In this study, we compared the effects of three doses of oxytocin infusion on hemodynamice changes at cesarean delivery. This study was double blind randomized clinical trial conducted on 120 patients who underwent cesarean delivery. Patients were randomly divided into 3 groups on the basis of dose of oxytocin to be given after delivery (group 1:10, group 2: 40; group 3: 80 units). Mean arterial blood pressure, heart rate, blood loss and received serum, uterine tone, nausea and vomiting were noted. There was a significant difference in vomiting (p=0.024), uterine tone (p=0.01), and requests for additional uterogenic drug (0.033). However, no significant difference was observed in hemodynamic changes (mean arterial blood pressure, heart rate), blood loss (0.264) and received serum (0.332) among three groups. According to the present study, higher doses of oxytocin are not recommended."