Acupuncture for erectile dysfunction: a randomized controlled trial.

Min Zhu, Fei Quan, Kaiyang Xue, Cai-hong Xiao, Jin Cui
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Abstract

OBJECTIVES To observe the clinical efficacy of acupuncture in treating erectile dysfunction (ED). METHODS A total of 64 ED patients were randomly divided into an acupuncture group (32 cases, 2 case dropped out) and a western medication group (32 cases, 2 cases dropped out). In the acupuncture group, acupuncture treatment was applied at Baihui (GV 20), Qihai (CV 6), Guanyuan (CV 4), Zhongji (CV 3), Dahe (KI 12), Qugu (CV 2), Zusanli (ST 36), and etc., two groups of acupoints were used alternately, 30 min each time, once every other day. In the western medication group, 50 mg of sildenafil tablet was took orally 1 h before sexual activity. Both groups were treated for 30 d. The international index of erectile function citrate (IIEF-5) score, self rating anxiety scale (SAS) score, self rating depression scale (SDS) score, TCM syndrome score were observed before and after treatment, and in follow-up of 2 weeks after treatment completion, the serum testosterone (T) level was detected before and after treatment, and the clinical efficacy was evaluated in the two groups. RESULTS After treatment and in follow-up, the IIEF-5 scores were increased compared with those before treatment in the two groups (P<0.01). In follow-up, the IIEF-5 score in the acupuncture group was ascended compared with that in the western medication group (P<0.05). Except for the SDS and TCM syndrome scores in the western medication group of follow-up, the SAS scores, SDS scores, and the TCM syndrome scores were decreased after treatment and in follow-up compared with those before treatment in the two groups (P<0.01, P<0.05); in the acupuncture group, the SAS scores, SDS scores and the TCM syndrome scores after treatment and in follow-up were lower than those in the western medication group (P<0.01). After treatment, the serum T levels were increased compared with those before treatment in the two groups (P<0.01). The total effective rate of the acupuncture group was 83.3% (25/30), and it was 86.7% (26/30) in the western medication group, there was no significant difference in total effective rate between the two groups (P>0.05). CONCLUSIONS Acupuncture can effectively improve erectile function, anxiety and depression state, and TCM syndrome in ED patients, and has a advantage of posterior effect compared with western medication treatment.
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针灸治疗勃起功能障碍:随机对照试验。
目的观察针灸治疗勃起功能障碍(ED)的临床疗效。方法将64例ED患者随机分为针灸组(32例,2例退出)和西药组(32例,2例退出)。针刺组针刺百会(GV 20)、气海(CV 6)、关元(CV 4)、中极(CV 3)、大热(KI 12)、曲谷(CV 2)、足三里(ST 36)等穴位,两组穴位交替使用,每次 30 分钟,隔日 1 次。西药组在性生活前 1 h 口服 50 mg 西地那非片剂。观察两组患者治疗前后的枸橼酸国际勃起功能指数(IIEF-5)评分、焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分、中医综合征评分,治疗结束后随访2周,检测两组患者治疗前后的血清睾酮(T)水平,评价临床疗效。结果治疗后及随访中,两组患者的IIEF-5评分均较治疗前有所提高(P0.05)。结论针灸能有效改善ED患者的勃起功能、焦虑抑郁状态及中医综合征,与西药治疗相比具有后发优势。
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