Global, Regional, and National Burden and Trends of Maternal Hypertensive Disorders from 1990 to 2021: A Population-Based Study.

IF 2.6 4区医学 Q2 OBSTETRICS & GYNECOLOGY International Journal of Women's Health Pub Date : 2025-12-06 eCollection Date: 2025-01-01 DOI:10.2147/IJWH.S550876

Li Yang, Wenting Xu

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Abstract

Objective: This study aimed to comprehensively assess the global, regional, and national burden and trends of maternal hypertensive disorders (MHD) from 1990 to 2021.

Methods: By analyzing MHD data from 1999 to 2021, age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR) and age-standardized disability-adjusted life years (ASDR) were screened, and estimated annual percentage change (EAPC) was calculated. This study used joinpoint regression analysis to examine trends during the period. This study investigated the differences in the burden of MHD among different Socio-demographic Index (SDI) regions through health inequalities analysis. Finally, we used the Bayesian age-period-cohort (BAPC) model to predict the trend in incidence, mortality, and DALYs rates of MHD over the next 25 years.

Results: The results showed that in 2021, the global ASIR, ASMR and ASDR were 461.94, 0.97 and 63.47, respectively (per 100000 population). From 1990 to 2021, the EAPC results showed a decreasing trend in the global ASIR, ASMR, and ASDR of MHD. The joinpoint regression results showed that the global ASIR, ASMR, and ASDR of MHD showed an overall downward trend from 1990 to 2021. Countries with lower SDI levels bore a higher burden. The predicted incidence, mortality, and DALYs rates of MHD for the next 25 years are both showing a downward trend.

Conclusion: The global ASIR, ASMR, and ASDR of MHD were all showing a downward trend from 1990 to 2021. However, this study found that Africa and low SDI regions bore a significant burden. The disparity in economic development could lead to an exacerbation of health inequalities. Therefore, it was emphasized that relevant public health policies should be formulated for African and low SDI regions. Medical staff should raise awareness of the risks of MHD and actively handle emergencies caused by MHD to reduce mortality, and DALYs rates and alleviate social burden.

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1990年至2021年全球、地区和国家孕产妇高血压疾病负担和趋势：一项基于人群的研究

目的：本研究旨在全面评估1990年至2021年全球、地区和国家孕产妇高血压疾病（MHD）负担和趋势。方法：通过分析1999 - 2021年MHD数据，筛选年龄标准化发病率（ASIR）、年龄标准化死亡率（ASMR）和年龄标准化残疾调整生命年（ASDR），计算估计年变化百分比（EAPC）。本研究使用联结点回归分析来检验这一时期的趋势。本研究通过健康不平等分析，探讨不同社会人口指数（SDI）区域MHD负担的差异。最后，我们使用贝叶斯年龄-时期-队列（BAPC）模型来预测MHD在未来25年的发病率、死亡率和DALYs率的趋势。结果：结果显示，2021年全球ASIR、ASMR和ASDR分别为461.94、0.97和63.47（每10万人口）。从1990年到2021年，EAPC结果显示MHD的全球ASIR、ASMR和ASDR呈下降趋势。联合点回归结果显示，1990 - 2021年，MHD全球ASIR、ASMR和ASDR总体呈下降趋势。SDI水平较低的国家负担较高。未来25年MHD的预测发病率、死亡率和DALYs率均呈下降趋势。结论：1990 - 2021年全球MHD患者ASIR、ASMR、ASDR均呈下降趋势。然而，本研究发现，非洲和低SDI地区承受着巨大的负担。经济发展的差距可能导致卫生不平等的加剧。因此，强调应针对非洲和低SDI区域制定相关的公共卫生政策。医务人员应提高对MHD风险的认识，积极处理由MHD引起的突发事件，以降低死亡率和DALYs率，减轻社会负担。

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来源期刊

International Journal of Women's Health OBSTETRICS & GYNECOLOGY-

CiteScore

3.70

自引率

0.00%

发文量

194

审稿时长

16 weeks

期刊介绍： International Journal of Women''s Health is an international, peer-reviewed, open access, online journal. Publishing original research, reports, editorials, reviews and commentaries on all aspects of women''s healthcare including gynecology, obstetrics, and breast cancer. Subject areas include: Chronic conditions including cancers of various organs specific and not specific to women Migraine, headaches, arthritis, osteoporosis Endocrine and autoimmune syndromes - asthma, multiple sclerosis, lupus, diabetes Sexual and reproductive health including fertility patterns and emerging technologies to address infertility Infectious disease with chronic sequelae including HIV/AIDS, HPV, PID, and other STDs Psychological and psychosocial conditions - depression across the life span, substance abuse, domestic violence Health maintenance among aging females - factors affecting the quality of life including physical, social and mental issues Avenues for health promotion and disease prevention across the life span Male vs female incidence comparisons for conditions that affect both genders.