Peritoneal membrane transport for low molecular weight substances with the use of one bag dialysate collection.

M Ikonomou, K Katopodis, P Nousia, E Tzalavra, E Koliousi, B Tsaliou, A Katsaraki, V Betsiou, A Dimitriou, J Theodorou, K C Siamopoulos
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Abstract

The 24-hour collection of dialysate provides an accurate method for evaluation of both adequacy of dialysis and peritoneal membrane transport characteristics in patients on chronic ambulatory peritoneal dialysis. However, this test requires 24 hours to complete and therefore it is inconvenient for both patients and nurses in the every day practice. We determined the peritoneal membrane transport characteristics for low molecular weight substances of ten patients by using the dialysate collection of only one bag. Dialysate/plasma creatinine ratios were calculated for each of the 4 bags (DATT1, DATT2, DATT3, DATT4) as well as for the 24 hour dialysate (DATTo). We found a very good correlation between DATTo and the four DATTs. We therefore propose that the evaluation of the peritoneal membrane transport, at least for creatinine could be determined with the use of one bag dialysate collection.

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使用一袋透析液收集低分子量物质的腹膜运输。
24小时透析液收集为评估慢性非卧床腹膜透析患者的透析充分性和腹膜转运特性提供了一种准确的方法。然而,这项测试需要24小时才能完成,因此对患者和护士在日常实践中都不方便。我们通过仅收集一袋透析液来测定10例患者的低分子量物质的腹膜转运特性。计算4袋透析液(DATT1、DATT2、DATT3、DATT4)和24小时透析液(DATTo)的透析液/血浆肌酐比值。我们发现DATTo和四个datt之间有很好的相关性。因此,我们建议评估腹膜运输,至少对于肌酐可以确定使用一袋透析液收集。
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