Fertility with early reduction of ovarian reserve: the last straw that breaks the Camel's back.

Fertility research and practice Pub Date : 2017-10-11 eCollection Date: 2017-01-01 DOI:10.1186/s40738-017-0041-1
Sabahat Rasool, Duru Shah
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Abstract

Diminished fertility and poor ovarian response pose a conundrum to the experts in the field of reproductive medicine. There is limited knowledge about the risk factors of diminished ovarian reserve other than the iatrogenic ones. One of the leading causes of infertility in women today is diminished ovarian reserve (DOR). DOR is characterized by a low number of eggs in a woman's ovaries and/or with poor quality of the remaining eggs, which boils down to impaired development of the existing eggs, even with assisted reproductive techniques. A good number of such women with low ovarian reserve may conceive with their own eggs, if they are given individualized treatment that is tailored for their profile. Such patients should be counseled appropriately for an aggressive approach towards achieving fertility. The sooner the treatment is started, the better the chances of pregnancy.

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卵巢储备早衰的生育力:压垮骆驼的最后一根稻草
生育力下降和卵巢反应低下是生殖医学专家面临的一个难题。除了先天性因素外,人们对卵巢储备功能减退的风险因素了解有限。卵巢储备功能减退(DOR)是导致当今女性不孕的主要原因之一。卵巢储备功能减退的特征是妇女卵巢中的卵子数量少和/或剩余卵子的质量差,这归结为现有卵子的发育受损,即使使用辅助生殖技术也是如此。卵巢储备功能低下的妇女中,有相当一部分人可以通过自己的卵子受孕,但要根据她们的具体情况进行个性化治疗。应为这类患者提供适当的咨询,使其积极地实现生育。越早开始治疗,怀孕的机会就越大。
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