A deep learning-based method for detecting and classifying the ultrasound images of suspicious thyroid nodules

Abstract

Purpose

The incidence of thyroid cancer has significantly increased in the last few decades. However, diagnosis of the thyroid nodules is labor and time intensive for radiologists and strongly depends on the personal experience of the radiologists. In this pursuit, the present study envisaged to develop a deep learning-based computer-aided diagnosis (CAD) method that enabled the automatic detection and classification of suspicious thyroid nodules in order to reduce the unnecessary fine-needle aspiration biopsy.

Methods

The CAD method consisted of two main parts: detecting the location of thyroid nodules using a multiscale detection network and classifying the detected thyroid nodules by an attention-based classification network.

Results

The performance of the proposed method was evaluated and compared with that of other state-of-the-art deep learning methods and experienced radiologists. The proposed detection method outperformed three other detection architectures (average precision, 82.1% vs. 78.3%, 77.2%, and 74.8%). Moreover, the classification method showed a superior performance compared with four other state-of-the-art classification networks (accuracy, 94.8% vs. 91.2%, 85.0%, 80.8%, and 72.1%) and that by experienced radiologists (mean value of area under the curve, 0.941 vs. 0.833).

Conclusions

Our study verified the high efficiency of the proposed detection method. The findings can help improve the diagnostic performance of radiologists. However, the developed CAD system requires more training and evaluation in a large-population study.