Cross-reacting surface proteins between different Escherichia coli O157:H7 strains and their immune responses in animal models

A. Nabi, F. Chowdhury, Z. Jahan, M. Sarkar, F. Rabbi, C. R. Ahsan
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Abstract

Enterohemorrhagic Escherichia. coli O157:H7 is one of the significant causes of food and waterborne illness in the developed nations across the globe. Transmission of the disease mainly occurs via the consumption of contaminated food, water and person to persontransmission1. Clinical spectrum of the disease includes watery diarrhea, bloody diarrhea, hemorrhagic colitis and life-threatening hemolytic uremic syndrome (HUS), which may develop in the people of all age groups.
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不同大肠杆菌O157:H7菌株的交叉反应表面蛋白及其在动物模型中的免疫反应
肠出血性大肠杆菌。O157:H7大肠杆菌是全球发达国家食物和水传播疾病的重要原因之一。该疾病的传播主要通过食用受污染的食物、水和人与人之间的传播1。该疾病的临床症状包括水样腹泻、带血腹泻、出血性结肠炎和危及生命的溶血性尿毒症综合征(HUS),这些疾病可能在所有年龄组的人中发生。
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