{"title":"高灵敏度碱性磷酸酶检测用碳点表面还原增强荧光。","authors":"Xiliang Yang, Suyi Wu, Yunjuan Zhang, Mingfeng Li, Xin Huang, Cui Liu, Chuan-Hua Zhou","doi":"10.1039/d6an00766j","DOIUrl":null,"url":null,"abstract":"<p><p>This study presents a sensing strategy based on reduction-boosted fluorescence of carbon dots for ALP detection, which exhibits a low limit of detection (LOD) of 0.65 U L<sup>-1</sup> and a linear range of 5-70 U L<sup>-1</sup>. This assay can be used to detect ALP in human serum, showing great potential for early diagnosis.</p>","PeriodicalId":63,"journal":{"name":"Analyst","volume":" ","pages":""},"PeriodicalIF":3.6000,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Surface reduction-boosted fluorescence of carbon dots for highly sensitive alkaline phosphatase sensing.\",\"authors\":\"Xiliang Yang, Suyi Wu, Yunjuan Zhang, Mingfeng Li, Xin Huang, Cui Liu, Chuan-Hua Zhou\",\"doi\":\"10.1039/d6an00766j\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This study presents a sensing strategy based on reduction-boosted fluorescence of carbon dots for ALP detection, which exhibits a low limit of detection (LOD) of 0.65 U L<sup>-1</sup> and a linear range of 5-70 U L<sup>-1</sup>. This assay can be used to detect ALP in human serum, showing great potential for early diagnosis.</p>\",\"PeriodicalId\":63,\"journal\":{\"name\":\"Analyst\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.6000,\"publicationDate\":\"2026-10-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Analyst\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1039/d6an00766j\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analyst","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d6an00766j","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
摘要
本研究提出了一种基于碳点还原增强荧光的ALP检测策略,其低检出限为0.65 U L-1,线性范围为5-70 U L-1。该方法可用于检测人血清ALP,具有早期诊断的潜力。
Surface reduction-boosted fluorescence of carbon dots for highly sensitive alkaline phosphatase sensing.
This study presents a sensing strategy based on reduction-boosted fluorescence of carbon dots for ALP detection, which exhibits a low limit of detection (LOD) of 0.65 U L-1 and a linear range of 5-70 U L-1. This assay can be used to detect ALP in human serum, showing great potential for early diagnosis.