Yilin Xing,Xinyu Song,Yuanyuan Liu,Wanting Fu,Xuannai Wang,Yuanli Ding,Zikun Wang
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引用次数: 0
Abstract
C–C bond cleavage and reconstruction of carboxylic acids is predominantly directed at the C–C(O) position. Herein, we have successfully developed a TfOH/HFIP cluster-promoted divergent strategy for the C–C bond cleavage of alkynoic acids and their subsequent reconstruction with arenes, affording selective access to distinct molecular architectures through tunable decarboxylation or deketonation. This platform not only facilitates mild decarboxylative functionalization but also establishes an unprecedented deketonative functionalization pathway for carboxylic acids.
期刊介绍：
Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.
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