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A Dual-Crosslinked Metallo-elastomer Platform for Architecture-Directed Vascular Remodeling 用于血管重构的双交联金属弹性体平台
IF 22.6 1区 工程技术 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2026-07-04 DOI: 10.1007/s42765-026-00744-9
Narangerel Gantumur, Shuhao Jiao, Xiaochu Ding, Simon Van Herck, Isabella Frangiosa, Emily Kopchick, Caitlin Maureen Purdy, Ty Walker, Aarati Kharal, Ying Grace Chen

The engineering of durable small-diameter vascular grafts remains constrained by the challenge of simultaneously achieving mechanical robustness, controlled degradation, and instructive scaffold architecture. Here, we report a programmable dual-crosslinked metallo-elastomer platform, poly(1,3-propylene itaconate-co-2,2′-bipyridine-5,5′-dicarboxylate-co-succinate-co-sebacate) (M-PBIS), that integrates dynamic metal–ligand coordination with covalent crosslinking to enable orthogonal control over network mechanics, time-dependent viscoelastic behavior, and processability. PBIS polymers were synthesized by modular step-growth polyesterification, allowing independent tuning of backbone composition, bipyridine ligand density for metal coordination, and alkene (C = C) content for covalent crosslinking. This multidimensional design space allowed systematic tuning of tensile elastic modulus (0.06–3.2 MPa), extensibility (53%–491%), toughness (66–1339 kJ m−3), creep resistance, and self-healing behavior, while maintaining controlled hydrolytic degradation and low physiological swelling (< 7%). Rheological analysis established a processing window supportive of conventional melt- and flow-based fabrication methods. To elucidate the role of scaffold architecture in vascular remodeling, M-PBIS was fabricated into small-diameter grafts using either poly(methyl methacrylate) (PMMA)-templated porous structures or electrowritten circumferentially-biased, helically wound fibers. In a rat carotid artery interposition model, electrowritten Zn-PBIS grafts maintained patency and dimensional stability through 21 weeks, supporting organized endothelialization, circumferential smooth muscle alignment, and structured extracellular matrix deposition. In contrast, PMMA-templated porous grafts underwent progressive dilation and structural instability during remodeling. These results demonstrate that dual-crosslinked metallo-elastomers combined with biomimetic circumferentially-biased fiber architecture enable mechanically resilient, biologically adaptive vascular grafts and establish M-PBIS as a manufacturable platform for resorbable small-diameter arterial reconstruction and other load-bearing soft-tissue applications.

Graphical abstract

持久的小直径血管移植物的工程仍然受到同时实现机械稳健性,可控降解和指导性支架结构的挑战的限制。在这里,我们报道了一个可编程的双交联金属弹性体平台,聚(1,3-丙烯酸-co-2,2 ' -联吡啶-5,5 ' -二羧酸-co-琥珀酸-co-癸二酸)(M-PBIS),它将动态金属配体配位与共价交联结合在一起,实现了对网络力学、随时间变化的粘弹性行为和可加工性的正交控制。PBIS聚合物是通过模块化阶梯生长聚合合成的,可以独立调整主链组成、金属配位的联吡啶配体密度和共价交联的烯烃(C = C)含量。这种多维设计空间允许系统调整拉伸弹性模量(0.06-3.2 MPa)、延伸性(53%-491%)、韧性(66-1339 kJ m−3)、抗蠕变和自愈行为,同时保持可控的水解降解和低生理肿胀(7%)。流变分析建立了一个支持传统的基于熔体和流动的制造方法的加工窗口。为了阐明支架结构在血管重构中的作用,我们使用聚甲基丙烯酸甲酯(PMMA)模板多孔结构或电写环偏置螺旋缠绕纤维将M-PBIS制成小直径的移植物。在大鼠颈动脉介入模型中,电写锌- pbis移植物在21周内保持通畅和尺寸稳定性,支持有组织的内皮化、周向平滑肌排列和结构化的细胞外基质沉积。相比之下,pmma模板多孔移植物在重塑过程中发生进行性扩张和结构不稳定。这些结果表明,双交联金属弹性体与仿生周向偏置纤维结构相结合,能够实现机械弹性、生物适应性血管移植物,并使M-PBIS成为可吸收的小直径动脉重建和其他承重软组织应用的可制造平台。图形抽象
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引用次数: 0
Fundamentals, Classification of Photonic Crystals and Their Applications in Textiles: A Review 光子晶体的基本原理、分类及其在纺织品中的应用综述
IF 22.6 1区 工程技术 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2026-07-01 DOI: 10.1007/s42765-026-00739-6
Shuai Li, Hongyan Zhang, Shengrong Ma, Haonan Li, Yuanshu Xiao, Jialiang Zhong, Guohua Shan, Ruofei Zhu, Lixia Jia, Zhengwei You

Traditional textile dyeing and printing processes are usually accompanied by severe environmental pollution, high water consumption, and heavy metal discharge, which pose a great threat to ecological sustainability and human health. To address these problems, the development of eco-friendly structural coloration strategies has become an urgent demand in modern textile engineering. Inspired by nature, animals and plants display diverse structural colors to fulfill survival, communication, and reproduction needs. This unique coloration enables tunable and vivid hues without relying on chemical dyes or pigments, which has spurred the rapid development of optical materials featuring structural color in fields such as color display, anti-counterfeiting, and smart sensing. Photonic crystals (PCs), a type of material that produces structural colors through the interaction between microstructure and light, have demonstrated significant potential in the field of textile green coloring. This is attributed to their straightforward preparation process, environmental friendliness, and excellent fading resistance. PC materials provide a brand-new and promising idea for clean coloring of textiles; however, there are few reviews in this field. Distinct from the previous reviews, we present an overview of the advancements in PCs structural color materials and emphasize their recent developments within the textile field. First, the chromogenic mechanism, definition, classification of PCs, and their current representative applications are introduced. Second, the utilization of PCs structural color materials in the textile field is examined, encompassing structural color fibers, yarns, and fabrics. Third, the current challenges faced by structural color fabrics are sorted out and analyzed in a problem-oriented manner, including the colorfastness, preparation efficiency, patterning and functionalization. The challenges and developmental prospects encountered by structural color textiles are comprehensively summarized. We envision that this review will guide the advancement of PC-based structural colors in textiles and inspire interdisciplinary research and practical applications across colloid chemistry, bionics, materials science, optics, and textile engineering.

Graphical Abstract

传统的纺织印染工艺通常伴随着严重的环境污染、高耗水量和重金属排放,对生态可持续性和人类健康构成极大威胁。为了解决这些问题,开发环保结构着色策略已成为现代纺织工程的迫切需求。受大自然的启发,动物和植物表现出不同的结构色彩,以满足生存、交流和繁殖的需要。这种独特的色彩可以在不依赖化学染料或颜料的情况下实现可调和生动的色调,这推动了具有结构色的光学材料在色彩显示,防伪和智能传感等领域的快速发展。光子晶体(PCs)是一种通过微观结构和光的相互作用产生结构色的材料,在纺织绿色着色领域显示出巨大的潜力。这是由于它们的制备工艺简单、环保、耐褪色性能优异。PC材料为纺织品的清洁着色提供了一种全新的前景;然而,这一领域的研究很少。与之前的评论不同,我们概述了pc结构颜色材料的进展,并强调了它们在纺织领域的最新发展。首先,介绍了pc的显色机理、定义、分类及其目前的代表性应用。其次,研究了涤纶结构色材料在纺织领域的应用,包括结构色纤维、纱线和织物。第三,以问题为导向,对结构色织物目前面临的挑战进行梳理和分析,包括色牢度、制备效率、图案化和功能化。全面总结了结构色纺织品面临的挑战和发展前景。我们设想这一综述将指导基于pc的结构色在纺织品中的发展,并激发胶体化学、仿生学、材料科学、光学和纺织工程等领域的跨学科研究和实际应用。图形抽象
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引用次数: 0
Safe 4 Ah Energy Storage Textiles with Ultrahigh Volumetric Energy Density and Excellent Environmental Adaptability 具有超高体积能量密度和优异环境适应性的安全4毫安储能纺织品
IF 22.6 1区 工程技术 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2026-06-25 DOI: 10.1007/s42765-026-00720-3
Zhiwei Yu, Jianli Cheng, Bin Wang

Fiber-shaped zinc-ion batteries (FZIBs) are regarded as highly promising candidates for next-generation flexible wearable electronics owing to their excellent electrochemical properties, high safety and weavability. Although increasing the loading of active materials enhances the energy density of FZIBs, their effective utilization is still hindered by insufficient interfacial adhesion and wettability, an inadequate electrode conductive network, and obvious polarization, especially in meter-long devices. Herein, a fabrication strategy for 40-m-level fiber cathodes based on synergistic coupling of an elastic adhesive network structure with a three-dimensional conductive network is proposed. The produced fiber cathodes are endowed with enhanced hydrophilicity, mechanical flexibility, and interfacial adhesion. Simultaneously, efficient conductive pathways along radial and axial directions are established, resulting in a more uniform electric field and ion distribution. Benefiting from these characteristics, the FZIBs deliver a high specific capacity of 303.99 mAh g−1, ultrahigh volumetric energy density of 112.61 mWh cm−3, and outstanding flexibility while maintaining 80.37% of the initial capacity after 100,000 bending cycles. The energy storage textile unit, woven from 8-m-long FZIBs, achieves a capacity of 1 Ah and demonstrates excellent environmental adaptability under conditions of −30 to 80 °C and negative pressure of −0.08 MPa. Moreover, a 4 Ah handbag assembled with four textile units is demonstrated to power various mobile devices, demonstrating promising potential for wearable electronics.

By employing an elastic bonding structure and a 3D conductive network strategy, fiber-shaped batteries exhibiting excellent mechanical flexibility and electrochemical performance are fabricated and assembled into a 4 Ah handbag. The elastic bonding structure enhances the interfacial adhesion of the fiber cathode and imparts superior bending durability, while the 3D conductive network improves electron transport and uniform ion distribution.

纤维形锌离子电池(fzib)由于其优异的电化学性能、高安全性和可编织性,被认为是下一代柔性可穿戴电子产品的极具前景的候选者。虽然增加活性材料的载荷可以提高fzbs的能量密度,但其有效利用仍然受到界面附着力和润湿性不足、电极导电网络不完善、极化明显等问题的阻碍,特别是在米长的器件中。本文提出了一种基于弹性粘接网络结构与三维导电网络协同耦合的40 m级光纤阴极制造策略。所制备的纤维阴极具有增强的亲水性、机械柔韧性和界面附着力。同时,建立了沿径向和轴向的高效导电通道,使电场和离子分布更加均匀。得益于这些特性,fzib具有303.99 mAh g−1的高比容量,112.61 mWh cm−3的超高体积能量密度,以及出色的灵活性,在100,000次弯曲循环后仍能保持80.37%的初始容量。该储能纺织装置由8米长的fzbs编织而成,容量为1 Ah,在- 30 ~ 80℃、- 0.08 MPa的负压条件下具有良好的环境适应性。此外,一个由四个纺织单元组装而成的4 Ah手袋被演示为各种移动设备供电,展示了可穿戴电子产品的巨大潜力。采用弹性键合结构和三维导电网络策略,制造出具有优异机械柔韧性和电化学性能的纤维型电池,并将其组装成4ah手提包。弹性键合结构增强了纤维阴极的界面附着力,赋予了优异的弯曲耐久性,而三维导电网络改善了电子传递和离子均匀分布。
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引用次数: 0
Electrospun Scaffold-Enabled Bioreactor for Scalable Manufacturing of Mechanically Programmed Macrophage-Derived Extracellular Vesicles Targeting Aged Bone Defects 电纺丝支架生物反应器用于可扩展制造针对老年性骨缺损的机械编程巨噬细胞来源的细胞外囊泡
IF 22.6 1区 工程技术 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2026-06-22 DOI: 10.1007/s42765-026-00733-y
Lingfei Xiao, Huayi Huang, Yunxiang Ding, Ming Lei, Qingjian Lei, Feifei Yan, Chaoran Shi, Jianbin Xu, Lin Cai, Wanli Li

Extracellular vesicles (EVs) represent promising cell-free therapeutics for the regeneration of aged bone defects. Mechanical stimulation is critical in bone regeneration and significantly influences both EV secretion and cargo composition. Despite this, translating mechanically programmed EVs to clinically relevant doses remains a significant challenge. Most current scalable bioreactor systems has achieved high yields through high-density cell culture and fluid flow, yet they do not provide programmable or spatially consistent mechanical stimulation. In this study, an electrospun scaffold-enabled bioreactor was developed to integrate high-density three-dimensional macrophage culture with programmable cyclic stretching, enabling simultaneous EV scale-up and cargo programming. The interconnected fiber junction network transmits boundary-applied strain with enhanced spatial consistency, while the highly porous scaffold supports dense cell seeding and efficient EV release and collection. This approach increases EV yield by 13.8-fold compared to conventional two-dimensional culture. Fiber-mediated mechanical conditioning activates Piezo1-dependent Ca2+ signaling and integrin-associated mechanotransduction, promotes Yes-associated protein (YAP) nuclear translocation, and remodels EV cargo composition. The resulting mechanically stimulated EVs (ms-EVs) demonstrate concurrent pro-regenerative activities, including cellular rejuvenation, vascular repair, and osteogenic enhancement, and perform favorably compared to canonical interleukin-4 (IL-4)-polarized M2 macrophage-derived extracellular vesicles (M2-EVs). In aged rat femoral defects, ms-EV-functionalized scaffolds increase bone volume fraction by approximately 1.7-fold at 8 weeks, reduce p16+ senescent cells, and enhance CD31+ neovascularization. These findings establish electrospun scaffolds as scalable mechanobiological manufacturing substrates for the production of functionally programmed EV therapeutics.

Graphical Abstract

细胞外囊泡(EVs)是一种很有前途的无细胞治疗方法,用于老年骨缺损的再生。机械刺激是骨再生的关键,并显著影响EV分泌和货物组成。尽管如此,将机械编程的电动汽车转化为临床相关剂量仍然是一个重大挑战。目前大多数可扩展的生物反应器系统通过高密度细胞培养和流体流动实现了高产量,但它们不能提供可编程或空间一致的机械刺激。在这项研究中,开发了一种电纺丝支架生物反应器,将高密度三维巨噬细胞培养与可编程循环拉伸结合起来,同时实现EV放大和货物编程。互连的纤维结网络传输边界施加的应变,增强了空间一致性,而高多孔支架支持密集的细胞播种和高效的EV释放和收集。与传统的二维培养相比,该方法可将EV产率提高13.8倍。纤维介导的机械调节激活piezo1依赖性Ca2+信号和整合素相关的机械转导,促进yes相关蛋白(YAP)核易位,并重塑EV货物组成。由此产生的机械刺激的细胞外囊泡(ms- ev)表现出同步的促再生活性,包括细胞再生、血管修复和成骨增强,并且与典型的白细胞介素-4 (IL-4)极化的M2巨噬细胞衍生的细胞外囊泡(M2- ev)相比表现更好。在老龄大鼠股骨缺损中,ms- ev功能化支架在8周时使骨体积分数增加约1.7倍,减少p16+衰老细胞,增强CD31+新生血管。这些发现确立了电纺丝支架作为可扩展的机械生物学制造基质,用于生产功能性程序化EV治疗药物。图形抽象
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引用次数: 0
Synaptic-Like Structured Hierarchically Oriented Fibrous Scaffolds Guide Integrin Mechanotransduction for Myocardial Repair 突触样结构分层定向纤维支架引导整合素机械转导心肌修复
IF 22.6 1区 工程技术 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2026-06-15 DOI: 10.1007/s42765-026-00731-0
Yuejie Chen, Shuai Ma, Chen Qian, Zijing Wu, Ge Tan, Jinfa Qin, Qihang Liu, Jiahao Li, Yang Wu, Li Zhang, Jinping Liu, Hongbing Deng

Myocardial infarction (MI) remains a severe threat to global health. The loss of cardiomyocytes and structural damage to the ventricles following MI lead to cardiac dysfunction. Current myocardial repair scaffolds promote tissue regeneration by mimicking the natural structure of myocardial tissue, yet suffer from the limitation of focusing on a single dimension of repair, failing to address the complex pathological microenvironment after MI characterized by ischemia, inflammation, and stress mismatch. To overcome this, our study has developed a multiscale bionic fibrous scaffold. The scaffold combines directional freezing with electrospinning technology. While constructing oriented channels that mimic natural myocardial tissue, it embeds nanofibers into the channel walls to form synapse-like microstructures. In vivo and in vitro experiments demonstrate that this scaffold synergistically promotes myocardial repair through multiple mechanisms: providing mechanical support, promoting angiogenesis, and regulating macrophage polarization. It significantly improves cardiac ejection function and inhibits ventricular remodeling. This repair mechanism results from the nanofiber synapse structure activating downstream intracellular signaling networks through its integrin binding sites, thereby regulating cellular behavior. In summary, this study provides a novel strategy for developing myocardial repair materials that synergistically regulate multicellular tissues and match complex pathological microenvironments.

Graphical Abstract

心肌梗死(MI)仍然是对全球健康的严重威胁。心肌细胞的损失和心室的结构损伤导致心功能障碍。目前的心肌修复支架通过模拟心肌组织的自然结构来促进组织再生,但存在专注于修复单一维度的局限,无法解决心肌梗死后以缺血、炎症、应激错配为特征的复杂病理微环境。为了克服这个问题,我们的研究开发了一种多尺度仿生纤维支架。该支架结合了定向冷冻和静电纺丝技术。在构建模拟天然心肌组织的定向通道时,它将纳米纤维嵌入到通道壁中,形成类似突触的微结构。体内和体外实验表明,该支架通过提供机械支持、促进血管生成、调节巨噬细胞极化等多种机制协同促进心肌修复。显著改善心脏射血功能,抑制心室重构。这种修复机制是由于纳米纤维突触结构通过其整合素结合位点激活下游细胞内信号网络,从而调节细胞行为。总之,本研究为开发协同调节多细胞组织和匹配复杂病理微环境的心肌修复材料提供了一种新的策略。图形抽象
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引用次数: 0
Mechano-intelligent Auxetic Triboelectric Textiles for Enhanced Energy Harvesting and AI-Driven Gesture Recognition 用于增强能量收集和人工智能驱动手势识别的机械智能辅助摩擦电纺织品
IF 22.6 1区 工程技术 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2026-05-29 DOI: 10.1007/s42765-026-00730-1
Yuanyuan Gao, Zhenyu Li, Minyu Qiu, Taosif Ahmed, Tingyi Yin, Xiangkun Bo, King Yan Chung, Hong Hu, Hong Fu, Bingang Xu

The advancement of wearable electronics, especially smart clothing, is limited by the rigidity and bulkiness of conventional power sources, highlighting the need for sustainable energy solutions. Textile-based triboelectric nanogenerators (T-TENGs) offer a promising approach for harvesting biomechanical energy and enabling self-powered sensing. However, traditional planar or simple 3D T-TENG structures often struggle to adapt efficiently to complex human motions, resulting in reduced electrical output and stability. In this study, we present a mechano-intelligent auxetic triboelectric textile (MIA-TENG) that integrates auxetic structures into the fabric to actively enhance contact and separation dynamics at the triboelectric interface. The MIA-TENG, fabricated from a composite of polydimethylsiloxane (PDMS) and nylon fabric, leverages the negative Poisson’s ratio effect of auxetic structures to enhance output performance with wearing comfort. Experimental results show that the MIA-TENG achieves a peak power output of 3610 mW m−2 and maintains excellent durability and washability, with a stable performance after 10 washing cycles and 60,000 mechanical tests. The device can power portable electronics and is suitable for both large-joint protection and high-fidelity gesture sensing. Combined with machine learning algorithms, the system enables accurate gesture recognition, offering an integrated platform for advanced applications in motion capture, health monitoring, and smart sports.

Graphical Abstract

可穿戴电子产品,特别是智能服装的进步,受到传统电源的刚性和体积的限制,突出了对可持续能源解决方案的需求。基于纺织品的摩擦电纳米发电机(t - teng)为收集生物机械能和实现自供电传感提供了一种很有前途的方法。然而,传统的平面或简单的3D T-TENG结构往往难以有效地适应复杂的人体运动,导致电力输出和稳定性降低。在这项研究中,我们提出了一种机械-智能互助性摩擦电纺织品(MIA-TENG),它将互助性结构集成到织物中,以主动增强摩擦电界面的接触和分离动力学。MIA-TENG由聚二甲基硅氧烷(PDMS)和尼龙织物的复合材料制成,利用消长结构的负泊松比效应来提高输出性能和穿着舒适性。实验结果表明,MIA-TENG的峰值输出功率为3610 mW m−2,并保持了优异的耐久性和耐洗性,经过10次洗涤和6万次机械测试后,性能稳定。该装置可以为便携式电子设备供电,适用于大关节保护和高保真手势感应。结合机器学习算法,该系统可实现精确的手势识别,为运动捕捉、健康监测和智能运动等高级应用提供集成平台。图形抽象
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引用次数: 0
Janus AgNWs Deposited Composite Membrane-Yarn for Multi-Functional Wearable Electronics: Electromagnetic Interference Shielding, Strain Sensing, Joule Heating 用于多功能可穿戴电子产品的Janus AgNWs沉积复合膜纱:电磁干扰屏蔽、应变传感、焦耳加热
IF 22.6 1区 工程技术 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2026-05-29 DOI: 10.1007/s42765-026-00734-x
Tao Yan, Xiaole Tao, Hong Lei, Shidong Ma, Bin He, Yuting Wu, Zhijuan Pan

Flexible multi-functional yarn plays a significant role in the development of flexible wearable devices. In this work, the influence of the components of silver nanowires (AgNWs) with two different lengths, their assembly methods with polyurethane (TPU), the spraying volume of AgNWs and the pre-stretching process on the sensing performance were systematically investigated to develop TPU/AgNWs strain sensing yarn (TASY). The synchronous optimization of multi-functions was achieved by establishing Janus asymmetric conductive networks. The Janus composite nanofiber membrane showed an outstanding electromagnetic interference shielding performance with around 40 dB and high shielding efficiency of 99.99%. The strain range of TASY can reach 122%, and the gauge factor within the linear interval of 0–80% was 37.34 with the high linearity of 0.984. Meanwhile, bending and twisting deformations can also be effectively detected. In addition, TASY can reach a temperature of 108 ℃ at a low voltage of 1.4 V. The linear relationship between temperature and the square of voltage was as high as 0.998. The power density was greater than 4500 W/m2. The high stability was achieved for Joule heating and strain sensing. The excellent comprehensive performance can provide support to develop the multi-functional wearable electronics.

Graphical Abstract

柔性多功能纱线在柔性可穿戴设备的发展中发挥着重要作用。本文系统地研究了两种不同长度银纳米线(AgNWs)的组成、与聚氨酯(TPU)的组装方式、AgNWs的喷涂量和预拉伸工艺对传感性能的影响,以开发TPU/AgNWs应变传感纱(TASY)。通过建立Janus不对称导电网络,实现了多种功能的同步优化。Janus复合纳米纤维膜具有良好的电磁干扰屏蔽性能,屏蔽效率高达99.99%,屏蔽强度约为40 dB。TASY的应变范围可达122%,0 ~ 80%线性区间内的应变系数为37.34,线性度为0.984。同时,还可以有效地检测弯曲和扭转变形。此外,TASY在1.4 V的低电压下可以达到108℃的温度。温度与电压的平方成线性关系高达0.998。功率密度大于4500w /m2。对焦耳加热和应变传感具有较高的稳定性。其优异的综合性能可为开发多功能可穿戴电子产品提供支持。图形抽象
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引用次数: 0
Ultrathin and Mechanically Robust Polyacrylonitrile-Based Solid Polymer Electrolytes Enabling Long-Cycle-Life Lithium Metal Batteries 超薄和机械坚固的聚丙烯腈基固体聚合物电解质实现长循环寿命的锂金属电池
IF 22.6 1区 工程技术 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2026-05-27 DOI: 10.1007/s42765-026-00726-x
Yimin Zhang, Dipsikha Ganguly, Abhinav Tandon, Tingting Yan, Fuwang Guan, Srija Ghosh, Kingshuk Roy, Stefan Adams, Longdi Cheng, Seeram Ramakrishna

Polyacrylonitrile-based solid polymer electrolytes (PAN-SPEs) have emerged as promising candidates for lithium-metal batteries owing to their advantages of safety, processability, and oxidative stability. However, ultrathin PAN-SPEs (<30 μm) still suffer from low ionic conductivity and poor mechanical strength. Herein, a strategy combining dipole-dipole interactions and doping with inorganic particles is proposed to construct continuous lithium ion (Li+) transport channels. The nitrile groups in PAN facilitate Li+ transport via Lewis acid-base interactions while inhibiting anion migration. Additionally, a soft exterior/rigid interior architecture was constructed through hot pressing and solution casting, achieving an ultrathin thickness of 27.8 μm with outstanding mechanical robustness. As a result, the designed PAN-SPEs demonstrate high ionic conductivity (4.42×10-4 S cm-1) together with a large elongation at break (168.5%). Leveraging these synergistic advantages, the symmetric cell exhibits excellent dendrite suppression for over 1200 hours, and the Li||SPEs||LiFePO4 cells deliver capacity retentions of 81.0% at 0.5C and 73.3% at 2C. This work provides a design paradigm for developing high-performance PAN-SPEs for lithium metal batteries.

Graphical abstract

聚丙烯腈基固体聚合物电解质(pan - spe)由于其安全性、可加工性和氧化稳定性等优点,已成为锂金属电池的有希望的候选者。然而,超薄pan - spe (<30 μm)仍然存在离子电导率低和机械强度差的问题。本文提出了一种结合偶极-偶极相互作用和无机粒子掺杂的策略来构建连续的锂离子(Li+)输运通道。PAN中的腈基团通过路易斯酸碱相互作用促进Li+的运输,同时抑制阴离子的迁移。此外,通过热压和溶液铸造,构建了柔软的外部/刚性的内部结构,获得了27.8 μm的超薄厚度,具有出色的机械坚固性。结果表明,pan - spe具有较高的离子电导率(4.42×10-4 S cm-1)和较高的断裂伸长率(168.5%)。利用这些协同优势,对称电池表现出良好的树突抑制超过1200小时,Li||SPEs||LiFePO4电池在0.5C和2C时的容量保留率分别为81.0%和73.3%。这项工作为开发高性能锂金属电池pan - spe提供了一个设计范例。图形抽象
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引用次数: 0
Hydrogel Microfibers-Mediated Engineering Vascularized High-Cell-Density Tissues with Structural Developmental Reinforcement 水凝胶微纤维介导的具有结构发育增强的工程血管化高密度组织
IF 22.6 1区 工程技术 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2026-05-22 DOI: 10.1007/s42765-026-00725-y
Xinyu Zhang, Xiule Wu, Yuting Chu, Lin Gu, Menglin Liang, Yudong Yao, Xueping Wang, Yuan Jin, Lei Shao

Engineering vascularized high-cell-density (HCD) tissues is pivotal for recapitulating the physiological functions of biomimetic constructs in vitro. However, traditional strategy that directly mix high-density cells with polymeric hydrogels remain challenging. To address these bottlenecks, might we move beyond the traditional strategy of mixing high-density cells with dense polymer hydrogels? Instead, could the self-sustained proliferation of basic cells together with endothelial vascularization be harnessed to construct vascularized HCD tissues exhibiting structural developmental reinforcement? Here, by integrating fiber-inducing factors from natural cell-extracellular matrix (ECM) structures with porous matrices, we propose a model where biomimetic structural units are directly mixed with a specific quantity of basic cells to construct a porous structural carrier that confines cells to two-dimensional constraints within microfibers. The two-dimensional constraint method using microfiber units eliminates the confining constraints of traditional hydrogel networks on cells, providing ample physiological space for rapid extension, migration, and proliferation. Meanwhile, the strategy of combining microfiber units with porous hydrogels significantly enhances structural porosity while ensuring structural integrity and strength, preventing collapse. Within this porous biomimetic microfiber system, basic cells proliferate continuously, strengthening intercellular interactions and reinforcing the structure’s overall mechanical properties and stability. Furthermore, the microfibrillar framework provides ECM-like cues that promote ordered expansion and spontaneous vascular formation. Introducing human bone marrow-derived mesenchymal stem cells (BMSCs) enables paracrine pro-angiogenic signaling to stimulate endothelial proliferation and migration. The synergistic effect of spatial structural induction and biological signaling stimulation significantly promotes the generation and maturation of vascular-like structures within the system. The tissue engineering strategy of mixing biomimetic microfiber units with a specific quantity of basic cells overcomes the limitations of traditional methods involving direct mixing of dense polymer hydrogels with large numbers of cells. This approach offers a novel solution for constructing vascularized, HCD tissues with physiological strength.

Graphical Abstract

工程血管化高细胞密度(HCD)组织是在体外重现仿生构建体生理功能的关键。然而,直接将高密度细胞与聚合物水凝胶混合的传统策略仍然具有挑战性。为了解决这些瓶颈问题,我们是否可以超越将高密度电池与致密聚合物水凝胶混合的传统策略?相反,是否可以利用基础细胞的自我持续增殖和内皮血管化来构建具有结构发育增强的血管化HCD组织?在这里,通过将天然细胞-细胞外基质(ECM)结构中的纤维诱导因子与多孔基质相结合,我们提出了一个模型,其中仿生结构单元直接与特定数量的基本细胞混合,以构建多孔结构载体,将细胞限制在微纤维内的二维约束中。利用超细纤维单元的二维约束方法消除了传统水凝胶网络对细胞的限制性约束,为细胞的快速延伸、迁移和增殖提供了充足的生理空间。同时,超细纤维单元与多孔水凝胶相结合的策略,在保证结构完整性和强度的同时,显著提高了结构孔隙度,防止了结构坍塌。在这种多孔仿生微纤维系统中,基本细胞不断增殖,加强了细胞间的相互作用,增强了结构的整体力学性能和稳定性。此外,微纤维框架提供了类似ecm的线索,促进有序扩张和自发血管形成。引入人骨髓间充质干细胞(BMSCs)可使旁分泌促血管生成信号刺激内皮细胞增殖和迁移。空间结构诱导和生物信号刺激的协同作用显著促进了系统内血管样结构的产生和成熟。将仿生微纤维单元与特定数量的基本细胞混合的组织工程策略克服了传统方法直接将致密聚合物水凝胶与大量细胞混合的局限性。这种方法为构建具有生理强度的血管化HCD组织提供了一种新的解决方案。图形抽象
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引用次数: 0
Multifunctional Textile Electronics Based on Triboelectric Nanogenerator with Electrochemical Synergy for Parkinson’s Disease Management 基于摩擦电纳米发电机的多功能纺织电子与电化学协同治疗帕金森病
IF 22.6 1区 工程技术 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2026-05-13 DOI: 10.1007/s42765-026-00727-w
Hongwei Chu, Qiuqian Ou, Liangling Cai, Zhenhe Huang, Haoyu Wang, Yue Hu, Yujian Liu, Jiyu Li, Yuyu Gao, Linhui Shen, Jialin Liu, Yingchun Li, Xinge Yu

Parkinson’s disease (PD) affects tens of millions of people globally, yet current clinical management remains fragmented, relying on subjective assessments and episodic laboratory measurements that fail to capture disease dynamics in real-world settings. Here, we present a smart textile-integrated multimodal interface (STMI) that seamlessly combines tremor quantification with real-time therapeutic drug monitoring through a wearable wristband platform. The system integrates an array of enhanced triboelectric nanogenerators with optimized bead-on-string nanofiber architecture for sensitive tremor detection, coupled with fiber-based electrochemical sensors for simultaneous monitoring of levodopa (LD), pH, and sodium levels in sweat. By leveraging deep learning algorithms (bidirectional LSTM), the STMI achieves accurate discrimination between healthy controls, prodromal Parkinson’s patients, and PD patients—including early detection of prodromal stages currently undetectable by standard imaging. Longitudinal tracking in PD patients demonstrates real-time correlation between tremor suppression and LD pharmacokinetics, enabling quantitative assessment of medication efficacy and identification of wearing-off phenomena. The textile-based form factor ensures ergonomic wearability and mechanical robustness for continuous monitoring, while the integrated multimodal sensing paradigm establishes a new standard for personalized PD management. This work demonstrates how intelligent wearable systems can bridge the gap between motor symptom assessment and pharmacological profiling, transforming PD care from episodic clinical visits to continuous, data-driven therapeutic optimization.

Graphical Abstract

帕金森病(PD)影响全球数千万人,但目前的临床管理仍然分散,依赖于主观评估和偶发性实验室测量,无法捕捉现实环境中的疾病动态。在这里,我们提出了一种智能纺织品集成多模态接口(STMI),通过可穿戴腕带平台将震颤量化与实时治疗药物监测无缝结合。该系统集成了一系列增强的摩擦电纳米发电机和优化的串珠纳米纤维结构,用于敏感的震颤检测,再加上基于纤维的电化学传感器,用于同时监测汗液中的左旋多巴(LD)、pH和钠水平。通过利用深度学习算法(双向LSTM), STMI实现了健康对照、前驱帕金森患者和PD患者之间的准确区分,包括目前标准成像无法检测到的前驱阶段的早期检测。PD患者的纵向跟踪显示震颤抑制与LD药代动力学之间的实时相关性,可以定量评估药物疗效并识别药物的磨损现象。基于纺织品的外形因素确保了人体工程学的可穿戴性和连续监测的机械稳健性,而集成的多模态传感范例为个性化PD管理建立了新的标准。这项工作展示了智能可穿戴系统如何弥合运动症状评估和药理学分析之间的差距,将PD护理从偶发性临床就诊转变为连续的、数据驱动的治疗优化。图形抽象
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引用次数: 0
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Advanced Fiber Materials
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