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Genetic modification of sorghum for improved nutritional value: state of the problem and current approaches 提高高粱营养价值的基因改造:问题的现状和目前的方法
Pub Date : 2018-10-10 DOI: 10.15406/JIG.2018.05.00076
L. Elkonin, Juliya Italyanskaya, V. M. Panin
Global warming is one of the most serious problems that threaten the existence of mankind. The results of observations carried out in different countries clearly demonstrate the steady tendency to increase the average annual temperature on the Earth during the last 150 years.1 For example, in the Russian Federation, in the next 15years, in the summer season, the temperature will rise by 1.4-1.50C in all grainproducing regions.2 In the next 40years, depending on the rate of increase of the greenhouse effect, the temperature will rise by 2.03.30C. In this connection, the creation of heat-tolerant and droughtresistant varieties and hybrids, the introduction of drought-resistant crops into agricultural production become extremely urgent problems of genetics and plant breeding.
全球变暖是威胁人类生存的最严重问题之一。在不同国家进行的观测结果清楚地表明,在过去150年中,地球上的年平均温度有稳定上升的趋势例如,在俄罗斯联邦,在未来15年,在夏季,所有粮食产区的温度将上升1.4-1.5℃在未来的40年里,根据温室效应的增加速度,气温将上升2.03.30摄氏度。在这方面,创造耐热抗旱品种和杂交品种,将抗旱作物引入农业生产,成为遗传和植物育种中极为紧迫的问题。
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引用次数: 4
A revised root for the human Y chromosome differentiation and diversity landscape among North African populations 北非人群中人类Y染色体分化和多样性景观的修订根源
Pub Date : 2018-09-07 DOI: 10.15406/JIG.2018.05.00075
K. Bentayebi, A. Hajitou
The Y chromosome has a curious role in population Genetics and forensic genetics. It is male specific and constitutively haploid. It passes from father to son, and, unlike other chromosomes, largely escapes meiotic recombination. Two segments (the pseudoautosomal regions) do recombine with the X, but this amount to less than 3 Mb of its ~60-Mb length, which makes it easier to study than the autosomes.1 These traits, explains its use in an increasing number of studies, especially those that address the history of the human population and makes it easier to study than the autosomes. Nevertheless, the Y chromosome continues to be overshadowed in these studies by the autosomal chromosome and mtDNA, despite containing far more genetic information than either. One reason for the lagging position of the Y chromosome has been a delay in the generation of useful data. The first PHYLOGENETIC TREE for human mtDNA was published in 1987,2 and the first for the Y chromosome was published in 1989.3 Since then, Y-chromosome-based studies have slowly accumulated; with the maturation of sequencing and genotyping technologies, a tremendous increase in all kinds of genetic data looms. It is therefore an appropriate time to reflect on what the Y chromosome can offer to population-genetic studies.
Y染色体在群体遗传学和法医遗传学中有着奇特的作用。它是男性特有的,构成单倍体。它从父亲遗传给儿子,并且与其他染色体不同,它在很大程度上逃脱了减数分裂重组。两个片段(假常染色体区域)确实与X染色体重组,但在其约60mb的长度中,这一数量不到3mb,这使得它比常染色体更容易研究这些特征解释了它在越来越多的研究中的应用,特别是那些研究人类历史的研究,使它比常染色体更容易研究。然而,在这些研究中,Y染色体仍然被常染色体和mtDNA所掩盖,尽管它们所包含的遗传信息远远超过两者。Y染色体位置滞后的一个原因是产生有用数据的延迟。1987年发表了第一个关于人类mtDNA的系统发育树2,1989年发表了第一个关于Y染色体的系统发育树3,此后,基于Y染色体的研究逐渐积累;随着测序和基因分型技术的成熟,各种基因数据的急剧增加迫在眉睫。因此,这是一个适当的时间来思考Y染色体可以为群体遗传学研究提供什么。
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引用次数: 2
Genetically modified Mosquitoes-blessing or curse 转基因蚊子——是福还是祸
Pub Date : 2018-08-15 DOI: 10.15406/jig.2018.05.00074
Nidhi Sharma, S. Jain
In 1870 the discoveries of Pasteur and Koch had precipitated a search for a bacterial cause for many diseases including malaria. In 1880, Laveran meticulously examined the blood of 200patients and in 148 observed the crescentic bodies in all cases of malaria but never in those without malaria. He also noted that quinine removed these stages from the blood. Laveran quickly realized that he had found a parasitic protozoan which he called Oscillariamalariae.5 In initial 19th century, it was known that malaria was caused by a protozoan parasite that invaded and multiplied in red blood cells and, after a lot of confusion, that there were three species with specific periodicities and other characteristics responsible for benign tertian (Haemamoebavivax), malignant tertian (Laveraniamalariae) and quartan (Haemamoebamalariae) malaria now respectively Plasmodium vivax, P. falciparum and P. malariae.6
1870年,巴斯德和科赫的发现促成了对包括疟疾在内的许多疾病的细菌病因的研究。1880年,Laveran仔细检查了200名患者的血液,并在148年在所有疟疾病例中观察到新月形体,但从未在非疟疾患者中观察到。他还指出,奎宁可以将这些阶段从血液中清除。Laveran很快意识到他发现了一种寄生原生动物,他称之为振荡疟原虫。5在19世纪初,人们知道疟疾是由一种侵入红细胞并在红细胞中繁殖的原生动物寄生虫引起的,在经历了许多困惑之后,人们发现有三种具有特定周期性和其他特征的物种导致了良性疟原虫(Haemamoebavivax)。恶性疟(狐猴疟)和恶性疟(血阿米巴疟)现在分别为间日疟原虫、恶性疟原虫和疟疾疟原虫
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引用次数: 0
A review on microsatellite and mitochondrial DNA study of native eastern European cattle populations: the case of the Romanian grey 东欧原生牛种群的微卫星和线粒体DNA研究综述:以罗马尼亚灰牛为例
Pub Date : 2018-08-10 DOI: 10.15406/jig.2018.05.00073
Nurlign Mohammed
The cattle species, humpless taurine (Bos taurus) and zebu (Bos indicus) are believed to be originated from the aurochs, Bos primigenius through a domestication event that occurred 8,000-10,000 years before present (B.P.). However, the investigation of the sequence data of mitochondrial DNA (mtDNA) control region revealed that taurine and zebu cattle diverged 200,000–1,000,000years B.P. and domestications of taurine and zebu cattle were two independent events that occurred separately 8,000–10,000years B.P. The genetic diversity, origin, conservation and sustainable utilization of these breeds received world-wide attention for a long time.1 Mammalian mitochondrial DNA shows several special features such as absence of introns, maternal inheritance, the existence of single copy orthologous genes, lack of recombination events and high mutation rate. Sequence comparisons of mtDNA D-loop region have been widely used to evaluate genetic diversity and phylogenetic performance among individuals and populations of cattle.2 Cattle are an important livestock species that have played a special role in the human history and culture, and had a considerable impact on human society. The worldwide population of cattle is estimated to 1.4billion animals, of which 159million are found in Europe and Central Asia.3 Romania is among the top ten countries in the EU regarding the cattle population with 2,022,400 heads and a breed structure of 30.96% Romanian Spotted, 20.28% Romanian Black and White and 13.58% Romanian Brown, according to National Agency for Animal Improving and Reproduction from Romanian.4
牛种,无驼背牛磺酸(Bos taurus)和zebu (Bos indicus),被认为是起源于野牛(Bos primigenius),通过发生在距今8000 - 10000年前的驯化事件。然而,对线粒体DNA控制区序列数据的调查表明,牛磺酸牛和瘤牛在距今20万年至100万年之间发生分化,而牛磺酸牛和瘤牛的驯化是分别发生在距今8000万年至10000年之间的两个独立事件。牛磺酸牛和瘤牛的遗传多样性、起源、保护和可持续利用长期以来受到世界各国的关注哺乳动物线粒体DNA具有内含子缺失、母系遗传、存在单拷贝同源基因、缺乏重组事件和高突变率等特点。mtDNA d环区的序列比较已被广泛用于评价牛个体和群体之间的遗传多样性和系统发育表现牛是在人类历史文化中扮演着特殊角色的重要家畜物种,对人类社会产生了相当大的影响。据罗马尼亚国家动物改良和繁殖机构估计,全世界牛的数量约为14亿头,其中1.59亿头分布在欧洲和中亚。罗马尼亚是欧盟十大牛群之一,有2,022400头,品种结构为30.96%的罗马尼亚斑点,20.28%的罗马尼亚黑白和13.58%的罗马尼亚棕色
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引用次数: 0
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Journal of Investigative Genomics
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