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Welcoming ES&T’s 2025 Early Career Editorial Board
IF 10.8 1区 环境科学与生态学 Q1 ENGINEERING, ENVIRONMENTAL Pub Date : 2025-03-25 DOI: 10.1021/acs.est.5c0261310.1021/acs.est.5c02613
Gregory V. Lowry*, Zhiyong Jason Ren, Julie Beth Zimmerman and Margaret Mills, 
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引用次数: 0
Environmental Exposure, Epitranscriptomic Perturbations, and Human Diseases
IF 9.028 1区 环境科学与生态学 Q1 ENGINEERING, ENVIRONMENTAL Pub Date : 2025-03-24 DOI: 10.1021/acs.est.5c00907
Songbo Wei, Huan-Yu Tao, Zheng Duan, Yinsheng Wang
Epitranscriptomics is a rapidly evolving field, and it examines how chemical modifications on RNA regulate gene expression. Increasing lines of evidence support that exposure to various environmental agents can change substantially chemical modifications on RNA, thereby perturbing gene expression and contributing to disease development in humans. However, the molecular mechanisms through which environmental exposure impairs RNA modification-associated proteins (“reader”, “writer”, and “eraser” or RWE proteins) and alters the landscape of RNA modifications remain poorly understood. Here, we provide our perspectives on the current knowledge about how environmental exposure alters the epitranscriptome, where we focus on dynamic changes in RNA modifications and their regulatory proteins elicited by exposure to environmental agents. We discuss how these epitranscriptomic alterations may contribute to the development of human diseases, especially neurodegeneration and cancer. We also discuss the potential and technical challenges of harnessing RNA modifications as biomarkers for monitoring environmental exposure. Finally, we emphasize the need to integrate multiomics approaches to decipher the complex interplay between environmental exposure and the epitranscriptome and offer a forward-looking viewpoint on future research priorities that may inform public health interventions and environmental regulations.
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引用次数: 0
Electrochemically Assisted Calcium Silicate Utilization for Phosphate Recovery
IF 9.028 1区 环境科学与生态学 Q1 ENGINEERING, ENVIRONMENTAL Pub Date : 2025-03-24 DOI: 10.1021/acs.est.5c00378
Ju Luo, Zhengshuo Zhan, Weiquan Li, Xin Zhang, Yang Lei
Electrochemical pH-swing systems have demonstrated significant potential across diverse applications, including chemical production, carbon capture, and water treatment. However, conventional systems predominantly depend on costly ion exchange membranes, which are often plagued by fouling and scaling challenges. Here, we introduce an ingenious electrochemically assisted calcium silicate (EACS) system capable of achieving a rapid pH swing from 8.5 to 10 within 1 h through the in situ utilization of H+ and OH ions, eliminating the need for membranes. The EACS system incorporates a novel 3D-printed porous basket holder designed to house calcium silicate particles and a rod-shaped Ru–Ir anode. Under closed-circuit conditions, the packed calcium silicate reacts with H+ generated at the anode, releasing Ca2+ into bulk solution, while OH produced at the cathode accumulates, resulting in an elevated bulk pH. This mechanism enables the EACS system to achieve exceptional phosphorus recovery efficiency (88.4%–96.6%) from various waste streams, with energy consumption as low as 24.4 kWh kg P–1. Long-term continuous flow experiments demonstrate that periodic replacement of depleted silicate minerals sustains system efficiency and stability. Furthermore, comparative analysis reveals that while carbonate and silicate minerals are functionally viable, silicate minerals exhibit superior performance in removal kinetics, product purity, and reduced carbon emissions. Notably, the effluent from the EACS system, enriched with Ca2+ and characterized by a high pH, exhibits potential for direct air carbon capture. The proposed EACS system offers a transformative approach to environmental remediation and industrial applications, leveraging the fundamental principle of pH-swing to open new avenues for sustainable solutions.
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引用次数: 0
Enantiomer-Dependent Uptake of Chiral Nanoparticles in Macrophages Modulates the Inflammatory Response through the NF-κB Pathway
IF 9.028 1区 环境科学与生态学 Q1 ENGINEERING, ENVIRONMENTAL Pub Date : 2025-03-24 DOI: 10.1021/acs.est.4c12577
Jinghua Hao, Yijin Tian, Jie Tang, Nali Zhu, Zhigang Li, Lingxiangyu Li, Yawei Wang, Guibin Jiang
Infectious inflammation caused by pathogens or environmental pollutants remains a major global health issue. Therefore the development of novel strategies to efficaciously control infectious inflammation is urgently required. Nuclear factor-κB (NF-κB) as the central activator of pro-inflammatory genes plays a pivotal role in infectious inflammation. Here, nanoscale chirality was designed to modulate the inflammatory response through enantiomer-dependent blockade of the NF-κB signaling pathway. Chiral gold nanoparticles (AuNPs) with good cytocompatibility were prepared through a one-pot seedless method under wild conditions, showing efficacious alleviation of lipopolysaccharide (LPS)-induced inflammation in vitro and in vivo only by AuNPs with levorotatory chirality (L-AuNPs) rather than the dextrorotatory enantiomer (D-AuNPs). Mechanism investigation elucidated that lysosomal acidification of macrophages was inhibited through a high cellular uptake of L-AuNPs due to their weak interaction energy with cell membranes. Accordingly, the NF-κB rather than mitogen-activated protein kinase pathway was blocked by L-AuNPs through the selective inhibition of p65 phosphorylation, wherein the nuclear translocation of p65 was simultaneously depressed, so the secretion of pro-inflammatory mediators was reduced significantly. This study suggests that imparting chirality to nanoparticles can provide a novel protocol to efficaciously modulate health risks arising from infectious inflammation by improving the uptake of nanoparticles with anti-inflammatory activity.
由病原体或环境污染物引起的感染性炎症仍然是一个重大的全球健康问题。因此,迫切需要开发新的策略来有效控制感染性炎症。核因子-κB(NF-κB)是促炎症基因的核心激活因子,在感染性炎症中起着关键作用。在这里,我们设计了纳米级手性,通过对映体依赖性阻断 NF-κB 信号通路来调节炎症反应。在野生条件下,通过无籽一锅法制备了具有良好细胞相容性的手性金纳米粒子(AuNPs),结果表明只有具有左旋手性(L-AuNPs)而非右旋对映体(D-AuNPs)的AuNPs才能有效缓解脂多糖(LPS)诱导的体外和体内炎症。机理研究阐明,由于 L-AuNPs 与细胞膜的相互作用能量较弱,因此细胞对 L-AuNPs 的吸收率较高,从而抑制了巨噬细胞溶酶体的酸化。因此,L-AuNPs 通过选择性抑制 p65 磷酸化,阻断了 NF-κB 而非丝裂原活化蛋白激酶通路,同时抑制了 p65 的核转位,从而显著减少了促炎介质的分泌。这项研究表明,给纳米粒子赋予手性可以提供一种新的方案,通过提高对具有抗炎活性的纳米粒子的吸收,有效地调节感染性炎症引起的健康风险。
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引用次数: 0
Occurrence, Removal, and Risk Assessment of Antimicrobials and Their Transformation Products in Effluent from Australian Wastewater Treatment Plants
IF 9.028 1区 环境科学与生态学 Q1 ENGINEERING, ENVIRONMENTAL Pub Date : 2025-03-24 DOI: 10.1021/acs.est.5c00425
Jinglong Li, Jake W. O’Brien, Ben J. Tscharke, Rory Verhagen, Chang He, Katja M. Shimko, Xueting Shao, Naixiang Zhai, Tobias Hulleman, Jochen F. Mueller, Kevin V. Thomas
Despite Australia’s high antimicrobial use, their residues in wastewater and their impacts on receiving waters remain largely unknown. This study assessed the occurrence, removal, and risk for antimicrobial resistance (AMR) of 102 antimicrobial substances and selected transformation products (TPs) in wastewater effluent from 47 wastewater treatment plants (WWTPs) across Australia. Thirty-two antimicrobials and 13 TPs were detected, with 14 analytes occurring at >80% frequencies. Ampicillin, penicillin V, penicilloic V acid, fluconazole, and tazobactam M1 were observed with high median concentrations of >0.2 μg/L. Collectively, the WWTPs released 5.4 kg/day or 0.54 g/day/1000 inhabitants of antimicrobials/TPs into natural waters, with β-lactams, quinolones, nitroimidazoles/azoles, and sulfonamides comprising high volumes, which was correlated with the population’s socioeconomic statuses. Thirty-seven analytes were removed at rates >80% post-treatment, whereas quinolones, nitroimidazoles/azoles, lincosamides, and macrolide TPs were observed with poor removal efficiencies, which were affected by treatment processes and regional climate. Comparing measured concentrations with the predicted no-effect concentrations for AMR selection (PNECAMR), 7 antimicrobials exerted selection risk for resistant bacteria. Concerningly, ciprofloxacin posed medium/high risk in most of the assessed WWTPs. The accumulative effects of antimicrobial classes and certain TPs might further aggravate adverse impacts on AMR development. Our study provides insights into the presence and AMR implications of antimicrobials in treated wastewater, aiming to safeguard public health and ecosystems.
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引用次数: 0
Dynamic Mn–VO Associates Boosted Molecular Oxygen Activation for Benzene Combustion on Mn-Doped Mesocrystalline CeO2
IF 9.028 1区 环境科学与生态学 Q1 ENGINEERING, ENVIRONMENTAL Pub Date : 2025-03-23 DOI: 10.1021/acs.est.4c14734
Xupeng Liu, Yanbiao Shi, Linghao Yu, Biao Zhou, Ziyue Chen, Furong Guo, Hao Li, Xiao Liu, Lizhi Zhang, Zhihui Ai
Highly efficient molecular oxygen activation over transition metal oxides toward catalytic abatement of aromatic volatile organic compounds (AVOCs) is possible yet challenging due to the easily deactivated surface oxygen vacancy (VO). Herein, dynamic Mn–VO associates were crafted onto the Mn-incorporated CeO2 mesocrystal (Mn/meso-CeO2) surface with Mn substituting a Ce atom through an easy-to-handle precipitation strategy. Experiments and theoretical calculation demonstrated that the asymmetric surface Mn–O–Ce configuration induced electron delivery from the low-valent Mn to adjacent Ce, destabilizing the circumambient O atoms and facilitating the formation of dynamic Mn–VO associates. Compared to pristine meso-CeO2, the Mn/meso-CeO2 with dynamic Mn–VO associates could efficiently activate O2 into a superoxide radical and a peroxanion (O2 and O22–) at higher reaction temperature (over 200 °C). Meanwhile, the O atom adjacent to Mn featuring substantially elevated Lewis acidity promoted the adsorption and activation of benzene. Consequently, the Mn/meso-CeO2 catalyst exhibited a superior catalytic oxidation reactivity (T90 = 215 °C) toward C6H6 combustion via a Langmuir–Hinshelwood mechanism. This work underlines the importance of rational design and regulation of catalytic sites over metal oxide surfaces for robust O2 activation and durable refractory AVOC combustion.
{"title":"Dynamic Mn–VO Associates Boosted Molecular Oxygen Activation for Benzene Combustion on Mn-Doped Mesocrystalline CeO2","authors":"Xupeng Liu, Yanbiao Shi, Linghao Yu, Biao Zhou, Ziyue Chen, Furong Guo, Hao Li, Xiao Liu, Lizhi Zhang, Zhihui Ai","doi":"10.1021/acs.est.4c14734","DOIUrl":"https://doi.org/10.1021/acs.est.4c14734","url":null,"abstract":"Highly efficient molecular oxygen activation over transition metal oxides toward catalytic abatement of aromatic volatile organic compounds (AVOCs) is possible yet challenging due to the easily deactivated surface oxygen vacancy (V<sub>O</sub>). Herein, dynamic Mn–V<sub>O</sub> associates were crafted onto the Mn-incorporated CeO<sub>2</sub> mesocrystal (Mn/meso-CeO<sub>2</sub>) surface with Mn substituting a Ce atom through an easy-to-handle precipitation strategy. Experiments and theoretical calculation demonstrated that the asymmetric surface Mn–O–Ce configuration induced electron delivery from the low-valent Mn to adjacent Ce, destabilizing the circumambient O atoms and facilitating the formation of dynamic Mn–V<sub>O</sub> associates. Compared to pristine meso-CeO<sub>2</sub>, the Mn/meso-CeO<sub>2</sub> with dynamic Mn–V<sub>O</sub> associates could efficiently activate O<sub>2</sub> into a superoxide radical and a peroxanion (O<sub>2</sub><sup>•</sup><sup>–</sup> and O<sub>2</sub><sup>2–</sup>) at higher reaction temperature (over 200 °C). Meanwhile, the O atom adjacent to Mn featuring substantially elevated Lewis acidity promoted the adsorption and activation of benzene. Consequently, the Mn/meso-CeO<sub>2</sub> catalyst exhibited a superior catalytic oxidation reactivity (<i>T</i><sub>90</sub> = 215 °C) toward C<sub>6</sub>H<sub>6</sub> combustion via a Langmuir–Hinshelwood mechanism. This work underlines the importance of rational design and regulation of catalytic sites over metal oxide surfaces for robust O<sub>2</sub> activation and durable refractory AVOC combustion.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"54 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143678070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unexpected Room-Temperature Selective Catalytic Reduction of NOx with NH3 over Metal-Free Carbon-Based Catalysts
IF 9.028 1区 环境科学与生态学 Q1 ENGINEERING, ENVIRONMENTAL Pub Date : 2025-03-23 DOI: 10.1021/acs.est.4c14482
Rucheng Duan, Yu Fu, Zhuocan Li, Xin Wang, Meng Gao, Yunbo Yu, Guangzhi He, Hong He
Catalysts operating at low temperatures are imperative for the denitrification of flue gases from various non-electric industries. Current catalysts typically exhibit significant activity for the selective catalytic reduction of NOx with NH3 (NH3–SCR) at temperatures above 100 °C. Here, we observed for the first time remarkable room-temperature NH3–SCR activity on the surface of carbon-based catalysts. The oxidation of NO to NO2 by surface C–O–C groups at room temperature serves as a key initial step, triggering a fast SCR reaction. The C–OH groups, as active sites, directly participate in the elementary reaction pathways of the SCR through an H migration process, significantly reducing the energy barrier of the rate-determining step to below 1 eV, thereby enabling fast SCR to occur at room temperature. The room-temperature SCR and its novel reaction mechanism reported in this study would inevitably expand the research boundaries of NOx abatement.
在低温下运行的催化剂对于各种非电力行业的烟气脱硝至关重要。目前的催化剂通常在 100 °C 以上的温度条件下表现出显著的氮氧化物与 NH3 选择性催化还原(NH3-SCR)活性。在此,我们首次在碳基催化剂表面观察到显著的室温 NH3-SCR 活性。室温下,表面 C-O-C 基团将 NO 氧化成 NO2,这是引发快速 SCR 反应的关键第一步。作为活性位点的 C-OH 基团通过 H 迁移过程直接参与了 SCR 的基本反应途径,从而将决定速率步骤的能障显著降低到 1 eV 以下,从而使快速 SCR 在室温下发生。本研究中报道的室温 SCR 及其新颖的反应机理势必会拓展氮氧化物减排的研究领域。
{"title":"Unexpected Room-Temperature Selective Catalytic Reduction of NOx with NH3 over Metal-Free Carbon-Based Catalysts","authors":"Rucheng Duan, Yu Fu, Zhuocan Li, Xin Wang, Meng Gao, Yunbo Yu, Guangzhi He, Hong He","doi":"10.1021/acs.est.4c14482","DOIUrl":"https://doi.org/10.1021/acs.est.4c14482","url":null,"abstract":"Catalysts operating at low temperatures are imperative for the denitrification of flue gases from various non-electric industries. Current catalysts typically exhibit significant activity for the selective catalytic reduction of NO<sub><i>x</i></sub> with NH<sub>3</sub> (NH<sub>3</sub>–SCR) at temperatures above 100 °C. Here, we observed for the first time remarkable room-temperature NH<sub>3</sub>–SCR activity on the surface of carbon-based catalysts. The oxidation of NO to NO<sub>2</sub> by surface C–O–C groups at room temperature serves as a key initial step, triggering a fast SCR reaction. The C–OH groups, as active sites, directly participate in the elementary reaction pathways of the SCR through an H migration process, significantly reducing the energy barrier of the rate-determining step to below 1 eV, thereby enabling fast SCR to occur at room temperature. The room-temperature SCR and its novel reaction mechanism reported in this study would inevitably expand the research boundaries of NO<sub><i>x</i></sub> abatement.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"71 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143678092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pattern Recognition-Driven Detection of Circadian-Disruptive Compounds from Gene Expressions: High-Throughput Screening and Experimental Verification 模式识别驱动的基因表达昼夜节律干扰化合物检测:高通量筛选与实验验证
IF 9.028 1区 环境科学与生态学 Q1 ENGINEERING, ENVIRONMENTAL Pub Date : 2025-03-22 DOI: 10.1021/acs.est.4c12466
Jierong Chen, Boyang Li, Shaoqi Zuo, Kun Zhang, Jiayin Dai, Lili Chen, Yanbin Zhao
Circadian rhythms regulate the timing of numerous biological functions in organisms. Besides well-known external stimuli like the light–dark cycle and temperature, circadian rhythms can also be modulated by environmental substances. However, this area remains largely underexplored. Here, we developed a robust Pattern Recognition-Driven Prediction Approach (PRD–PA) that enables the identification of circadian-disruptive compounds from large-scale zebrafish transcriptomic profiling. The approach utilizes a circadian gene panel consisting of over 270 Circadian-Indicating Genes (CIGs) with stable and robust periodicity and combines it with a predictive model, known as the Differential Gene Expression Values of an Individual Comparison Model (DGVICM), that can effectively predict internal circadian phases from transcriptomic samples. By analyzing 692 aggregated gene expression profiles across 40 environmental substances, several were identified as having significant circadian-disruptive potential. These include glucocorticoids (e.g., prednisone (PRE) and triamcinolone (TRI)), the antithyroid agent propylthiouracil (PTU), and the widely used UV filter benzophenone-3 (BP-3). Both glucocorticoids and PTU are well-documented disruptors of circadian rhythms, and BP-3’s circadian-disrupting properties were validated through experimental exposures. Moreover, BP-3 analogs, including 2,4-dihydroxybenzophenone (BP-1) and 2,2’-dihydroxy-4-methoxybenzophenone (BP-8), were also found to exhibit similar circadian-disruptive effects. Overall, the present findings demonstrated the reliability of the PRD–PA approach for circadian disruption screening and highlighted the presence of diverse circadian-disruptive substances in our environment.
昼夜节律调节生物体内多种生物功能的时间。除了众所周知的光暗周期和温度等外部刺激外,昼夜节律还能受到环境物质的调节。然而,这一领域在很大程度上仍未得到充分探索。在这里,我们开发了一种稳健的模式识别驱动预测方法(PRD-PA),可以从大规模斑马鱼转录组分析中识别出破坏昼夜节律的化合物。该方法利用由 270 多个具有稳定和稳健周期性的昼夜节律指示基因(CIGs)组成的昼夜节律基因面板,并将其与一个预测模型(称为个体比较模型的差异基因表达值(DGVICM))相结合,该模型可以从转录组样本中有效预测内部昼夜节律阶段。通过分析 40 种环境物质的 692 个聚合基因表达谱,确定了几种具有显著昼夜节律干扰潜力的物质。这些物质包括糖皮质激素(如泼尼松(PRE)和曲安奈德(TRI))、抗甲状腺药物丙基硫脲嘧啶(PTU)和广泛使用的紫外线过滤剂二苯甲酮-3(BP-3)。糖皮质激素和 PTU 都是有据可查的昼夜节律干扰物,BP-3 的昼夜节律干扰特性已通过实验暴露得到验证。此外,研究还发现 BP-3 类似物,包括 2,4-二羟基二苯甲酮(BP-1)和 2,2'-二羟基-4-甲氧基二苯甲酮(BP-8),也具有类似的昼夜节律干扰作用。总之,本研究结果证明了 PRD-PA 方法在昼夜节律干扰筛选方面的可靠性,并强调了我们环境中存在的多种昼夜节律干扰物质。
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引用次数: 0
Gaseous Air Pollutants and Lung Function in Fibrotic Interstitial Lung Disease (fILD): Evaluation of Different Spatial Analysis Approaches
IF 9.028 1区 环境科学与生态学 Q1 ENGINEERING, ENVIRONMENTAL Pub Date : 2025-03-22 DOI: 10.1021/acs.est.4c11275
Shuangjia Xue, Matthew J. Broerman, Gillian C. Goobie, Daniel J. Kass, James P. Fabisiak, Sally E. Wenzel, Seyed Mehdi Nouraie
Gaseous pollutants such as CO, NO2, O3, and SO2 are linked to adverse clinical outcomes in patients with fibrotic interstitial lung diseases (fILDs), particularly idiopathic pulmonary fibrosis. However, the effect of various exposure estimation methods on these findings remains unclear. This study aims to evaluate three spatial approaches─nearest neighbor (NN), inverse distance weighting (IDW), and Kriging─for estimating gaseous pollutant exposures and to assess how these methods affect health outcome estimates in fILD patients. A 10-fold cross-validation showed that Kriging had the lowest prediction error compared to NN and IDW, with RMSE for CO = 0.43 ppm (11%), O3 = 5.9 ppb (14%), SO2 = 2.7 ppb (12%), and NO2 = 7.6 ppb (9%), respectively. Kriging also excelled over other methods across wide spatial and temporal ranges, showing the highest spatial R2 for CO and O3 and the highest temporal R2 for SO2 and NO2. In a large cohort of patients with fILD, higher levels of CO, SO2, and NO2 exposure were associated with lower pulmonary function. The magnitude of association and its precision were higher in SO2 and CO estimated by the Kriging method. This study underscores Kriging as a robust method for estimating gaseous pollutant levels and offers valuable insights for future epidemiological studies.
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引用次数: 0
Exploring Environmental Behaviors and Health Impacts of Biodegradable Microplastics
IF 9.028 1区 环境科学与生态学 Q1 ENGINEERING, ENVIRONMENTAL Pub Date : 2025-03-21 DOI: 10.1021/acs.est.4c14716
Yuhao Yan, Jiexia Cheng, Jie Gao, Yanna Liu, Haijiang Tian, Yaquan Liu, Xuehan Zheng, Guangxuan Wang, Jingtai Yao, Yun Ding, Aifeng Liu, Minghao Wang, Jing Zhao, Shunhao Wang, Chunzhen Shi, Li Zeng, Xinyue Yang, Hua Qin, Xiulan Zhao, Runzeng Liu, Liqun Chen, Guangbo Qu, Bing Yan, Guibin Jiang
Biodegradable plastics (BPs) are promoted as eco-friendly alternatives to conventional plastics. However, compared to conventional microplastics (MPs), they degrade rapidly into biodegradable microplastics (BMPs), which may lead to a more significant accumulation of BMPs in the environment. This review systematically compares BMPs and MPs, summarizes current knowledge on their environmental behaviors and impacts on ecosystems and human health, and offers recommendations for future research. BMPs are detected in water, sediments, indoor dust, food, marine organisms, and human samples. Compared to MPs, BMPs are more prone to environmental transformations, such as photodegradation and biodegradation, which results in a shorter migration distance across different matrices. Like MPs, BMPs can adsorb pollutants and transport them into organisms, enhancing toxicity and health risks through the Trojan horse effect. Studies indicate that BMPs may negatively impact terrestrial and aquatic ecosystems more than MPs by disrupting nutrient cycling and inhibiting plant and animal growth. In vivo and in vitro research also shows that BMP degradation products increase bioavailability, exacerbating neurotoxicity and overall toxicity. However, findings on BMPs’ environmental and health effects remain inconsistent. Further evaluation of the trade-offs between BMP risks and their biodegradability is needed to address these uncertainties.
生物降解塑料(BPs)作为传统塑料的生态友好型替代品而得到推广。然而,与传统微塑料(MPs)相比,生物降解塑料能迅速降解为生物可降解微塑料(BMPs),这可能会导致生物可降解微塑料在环境中的大量积累。本综述系统地比较了 BMP 和 MP,总结了目前有关其环境行为以及对生态系统和人类健康的影响的知识,并对未来的研究提出了建议。在水、沉积物、室内灰尘、食物、海洋生物和人体样本中都能检测到 BMP。与 MPs 相比,BMPs 更容易发生光降解和生物降解等环境转化,因此在不同基质中的迁移距离更短。与 MPs 一样,BMPs 可吸附污染物并将其迁移到生物体内,通过特洛伊木马效应增强毒性和健康风险。研究表明,BMP 比 MP 更能破坏营养循环,抑制动植物生长,从而对陆地和水生生态系统产生负面影响。体内和体外研究还表明,BMP 降解产物增加了生物利用率,加剧了神经毒性和整体毒性。然而,有关 BMP 对环境和健康影响的研究结果仍不一致。需要进一步评估 BMP 风险与其生物降解性之间的权衡,以解决这些不确定因素。
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引用次数: 0
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