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Balancing the evidence: incorporating the synthesis of qualitative data into systematic reviews 平衡证据:将定性数据的综合纳入系统审查
Pub Date : 2004-02-27 DOI: 10.1111/j.1479-6988.2004.00008.x
Alan Pearson RN PhD FRCNA FAAG FRCN

Techniques for the systematic review of evidence of effectiveness are now well established. Health-care professionals argue, however, for a need to recognise evidence of appropriateness and feasibility and for the development of methodologies to appraise and synthesise the results of qualitative research. This paper describes a participatory project designed to develop systems to systematically review qualitative evidence. The Qualitative Assessment and Review Instrument is described in detail, and a suite of programs designed to conduct comprehensive reviews of evidence for health-care practice is outlined. As evidence-based practice increases in sophistication, and its influence in health service delivery expands, the need for broadening the view of what constitutes legitimate evidence is advanced by clinicians and the approach described attempts to achieve a balance in evidence review that recognises the value of quantitative and qualitative evidence.

对有效性证据进行系统审查的技术现已建立。然而,卫生保健专业人士认为,需要认识到适当性和可行性的证据,并开发评估和综合定性研究结果的方法。本文描述了一个参与性项目,旨在开发系统地审查定性证据的系统。对定性评估和审查工具进行了详细描述,并概述了一套旨在对医疗实践证据进行全面审查的程序。随着循证实践的复杂性增加,其在医疗服务提供中的影响力扩大,临床医生提出了扩大对什么是合法证据的看法的必要性,所描述的方法试图在证据审查中实现平衡,承认定量和定性证据的价值。
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引用次数: 273
Comparison of educational interventions for mental health consumers receiving psychotropic medication 接受精神药物治疗的心理健康消费者的教育干预比较
Pub Date : 2004-01-16 DOI: 10.1111/j.1479-697X.2004.00007.x
Rhonda D Griffiths, Ritin S Fernandez, Maria S Mostacchi, Venita Evans

Background One in four people globally will be affected by mental disorders at some point in their life. Currently approximately 450 million people worldwide suffer from this condition thereby placing mental health disorders among the leading cause of illness. Although treatment with psychotropic medication for specific psychological interventions has been demonstrated to be beneficial, it is also associated with relapse due to non-adherence to the medication regime. Factors associated with non-compliance include inadequate knowledge of the condition and the side-effects of the drugs. However, there is still some debate amongst psychiatrists as to the relative benefits of informing consumers about the side-effects.

Objectives The objective of this review was to systematically assess the literature and present the best available evidence that investigated the efficacy of educational interventions, relating to psychotropic medications, for consumers with a mental health disorder.

Search strategy A literature search was performed using the following databases Medline (1966–2000), CINAHL (1982–2002), EMBASE (1980–2002) ProQuest, Psychlit and the Cochrane Controlled Trials Register (Issue 2, 2002 of Cochrane Library). In addition, the reference lists of relevant trials and conference proceedings were also scrutinised. No language restrictions were applied. Experts and investigators were contacted to elicit further information.

Selection criteria All relevant randomised controlled trials that investigated the effectiveness of providing education and the methods to provide education to adult consumers with a mental illness were eligible for inclusion in the study.

Data collection and analysis Eligibility of the trials for inclusion in the review, details of eligible trials and the methodological quality of the trials was assessed jointly by two reviewers. All information was verified by a third reviewer. Odds ratio for dichotomous data and a weighted mean difference for continuous data were calculated with 95% confidence intervals. Where synthesis was inappropriate a narrative overview was undertaken.

Results Twenty-one studies were included in this review. Knowledge was assessed in 15 studies. Compliance was assessed in 13 studies. Relapse was assessed in five studies and insight was assessed in six studies. Those patients who were provided with education demonstrated a significant increase in the level of knowledge and compliance compared to those who were not. However, there was no difference in the incidence of relapse and insight in those who were provided education. A structured education session using both written and verbal methods followed by discussion was demonstrated to be effective. The evidence suggests that consumers who were provided multiple education sessions had greater knowledge g

背景全球四分之一的人在一生中的某个时刻会受到精神障碍的影响。目前,全世界约有4.5亿人患有这种疾病,从而将心理健康障碍列为疾病的主要原因之一。尽管针对特定心理干预的精神药物治疗已被证明是有益的,但由于不遵守药物制度,它也与复发有关。与不合规相关的因素包括对病情和药物副作用的了解不足。然而,对于告知消费者副作用的相对益处,精神科医生之间仍存在一些争论。目的本综述的目的是系统地评估文献,并提供最佳可用证据,调查与精神药物相关的教育干预措施对精神健康障碍消费者的疗效。检索策略使用以下数据库Medline(1966–2000)、CINAHL(1982–2002)、EMBASE(1980–2002)ProQuest、Psychlit和Cochrane对照试验登记册(Cochrane Library 2002年第2期)进行文献检索。此外,还仔细审查了相关审判和会议记录的参考名单。没有语言限制。联系了专家和调查人员以获取进一步信息。选择标准所有相关的随机对照试验都有资格纳入研究,这些试验调查了为患有精神疾病的成年消费者提供教育的有效性和提供教育的方法。数据收集和分析纳入审查的试验的资格、合格试验的细节和试验的方法质量由两名审查人员联合评估。所有信息均由第三位审查员核实。以95%置信区间计算二分数据的比值比和连续数据的加权平均差。如果综合不合适,则进行叙述性概述。结果本综述共纳入21项研究。在15项研究中对知识进行了评估。对13项研究的依从性进行了评估。在五项研究中评估了复发,在六项研究中对洞察力进行了评估。与未接受教育的患者相比,接受了教育的患者的知识水平和依从性显著提高。然而,接受教育者的复发率和洞察力没有差异。采用书面和口头方法,然后进行讨论的结构化教育课程被证明是有效的。证据表明,接受多次教育的消费者在短期内获得了更多的知识(高达1 月);然而,从长远来看,多次会议的有效性(2 年)没有结论。该综述提供的证据表明,在提高与药物相关的知识和对疾病的洞察力方面,多次教育比单一教育要好。结论来自试验的证据表明,作为精神疾病患者治疗计划的一部分,经常进行的结构化教育干预是有用的。迫切需要更精心设计和报道的随机研究来调查教育的有效性。
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引用次数: 0
Management of short-term indwelling urethral catheters to prevent urinary tract infections† 短期留置导尿管预防尿路感染的管理†
Pub Date : 2004-01-01 DOI: 10.1111/j.1365-2788.2004.00014.x
Craig Lockwood RN BN GradDipNSc(ClinNurs) MNSc, Tamara Page RN BN HyperbaricNursCert GradDipNSc(HighDep) MNSc, Tiffany Conroy-Hiller RN BN DipBusFLM, Zuben Florence RN GradDipNSc(Cardiac)
Background This systematic review updates a previous review published in 2000. The objective of this review was to present the best available evidence relating to the prevention of catheter‐associated urinary tract infections (UTI). Selection criteria This review considered randomised controlled trials (RCTs) of adult patients with short‐term urethral catheters. In the absence of RCTs, other research designs such as non‐randomised controlled trials and before and after studies were considered for inclusion. Interventions of interest were those related to the prevention of catheter‐related UTI and included: sterile versus non‐sterile insertion technique, special coatings to catheters versus standard non‐coated catheters, the use of flush solutions, the use of solutions added to urinary drainage bag, maintenance of a closed urinary drainage circuit, the use of antireflux valves, antibiotic creams applied to the external meatus‐catheter interface, meatal care regimens, education programs, and changed care delivery practices. This review was limited to short‐term urethral catheters, and so studies evaluating long‐term or suprapubic catheters were excluded. The primary outcome of interest was the difference in the rates of UTI between experimental intervention and the control. Search strategy The search included both published and unpublished studies with an initial limited search of MEDLINE and CINAHL databases undertaken to identify key words contained in the title or abstract, and index terms used to describe relevant interventions. A second extensive search used all identified key words and index terms. The third step included a search of the reference lists and bibliographies of relevant articles. The databases searched included: CINAHL, MEDLINE, Current Contents, Cochrane Library, Expanded Academic Index, and Embase. The Dissertation Abstracts International database was searched for unpublished studies. Assessment of methodological quality Methodological quality was assessed using a standardised checklist. Critical appraisal and data extraction were conducted by two independent reviewers; discrepancies were addressed through discussion with a third reviewer as required. Results There was no significant difference in infection rate using either sterile surgical or non‐sterile insertion technique. The use of water for cleansing prior to catheter insertion was recommended. There was no additional benefit from specific meatal care other than standard daily personal hygiene and removal of debris. Infection rates were similar for both latex and silicone catheters. Comparisons between silver and Teflon coating clearly favoured the silver alloy coating. The use of a complex closed drainage system in the intensive care environment did not confer any additional benefit. Studies comparing types of junction seals and use of junction seals either prior to or following catheterisation found no clear benefit from using either preconnected sealed systems or sea
背景本系统综述更新了2000年发表的先前综述。本综述的目的是提供与预防导尿管相关的尿路感染(UTI)相关的最佳可用证据。选择标准本综述考虑了使用短期导尿管的成年患者的随机对照试验。在没有随机对照试验的情况下,考虑纳入其他研究设计,如非随机对照试验和前后研究。感兴趣的干预措施是与预防导管相关的尿路感染有关的干预措施,包括:无菌与非无菌插入技术、导管特殊涂层与标准非涂层导管、冲洗溶液的使用、添加到尿液引流袋中的溶液的使用,封闭的尿液引流回路的维护,抗反流阀的使用,应用于外部肉导管接口的抗生素乳膏、肉护理方案、教育计划和改变的护理实践。本综述仅限于短期导尿管,因此排除了评估长期导尿管或耻骨上导尿管的研究。感兴趣的主要结果是实验干预和对照之间UTI发生率的差异。搜索策略搜索包括已发表和未发表的研究,对MEDLINE和CINAHL数据库进行了初步有限搜索,以确定标题或摘要中包含的关键词,以及用于描述相关干预措施的索引术语。第二次广泛搜索使用了所有已识别的关键字和索引项。第三步包括检索相关文章的参考文献列表和参考书目。检索到的数据库包括:CINAHL、MEDLINE、Current Contents、Cochrane Library、Expanded Academic Index和Embase。论文摘要国际数据库搜索未发表的研究。方法学质量评估方法学质量使用标准化检查表进行评估。两名独立审查员进行了关键评估和数据提取;根据需要,通过与第三位评审员讨论来解决差异。结果无菌手术和非无菌插入技术的感染率差异无统计学意义。建议在插入导管前用水清洗。除了标准的日常个人卫生和清除碎屑外,特定的肉类护理没有其他好处。乳胶导管和硅胶导管的感染率相似。银和特氟龙涂层之间的比较显然有利于银合金涂层。在重症监护环境中使用复杂的封闭排水系统并没有带来任何额外的好处。在导管插入之前或之后比较连接密封类型和连接密封使用的研究发现,使用预连接密封系统或添加银释放装置的密封系统没有明显的益处。在引流袋中添加氯己定和过氧化氢都不能有效降低尿路感染率。结果表明,与间歇导尿管相比,Foley导尿管引起的菌尿发生率更高(P <; 0.025)。单次随机对照试验检查了常规换袋与非常规换袋对尿路感染率的影响。常规换袋对降低感染风险没有好处。结论目前的随机对照试验证据表明,不需要使用外科无菌导管技术,自来水足以清洁生殖器。插入后,肉类区域周围的日常卫生与导管厕所一样有效;并且用银浸渍的导管可以减少导管相关菌尿的发生率。密封(如胶带、预密封)排水系统不应被视为预防细菌尿的唯一机制。在引流袋中添加抗菌溶液和常规更换引流袋对导管相关感染没有影响。然而,这次审查提出的大多数建议都是基于单一的研究,参与者人数往往有限。迫切需要在其他临床环境中复制这些研究。
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引用次数: 31
Clinical effectiveness of different approaches to peritoneal dialysis catheter exit-site care 不同入路腹膜透析导管出口护理的临床效果
Pub Date : 2003-11-10 DOI: 10.1046/j.1479-697X.2003.00006.x
Craig Lockwood RN BN GradDip (ClinNurs) MNSC,  Brent Hodgkinson MSc, Tamara Page RN BN HyperbaricNursCert GradDipNSc(HighDep)

Objective The objective of this review was to appraise and synthesise the best available evidence on the clinical effectiveness of peritoneal dialysis catheter exit-site care.

Inclusion criteria This review considered all randomised controlled trials that evaluated the effectiveness of peritoneal exit-site care. In the absence of randomised controlled trials, other controlled research designs such as non-randomised controlled trials were considered for inclusion in a narrative summary to enable the identification of current approaches and possible future strategies. Participants of interest were adults with chronic renal failure on maintenance peritoneal dialysis. Interventions of interest were those used to manage peritoneal catheter exit sites, and included types of dressings, frequency of dressings, types of skin care, and use of topical antiseptic or antimicrobial agents.

Search strategy The search sought to find both published and unpublished studies. An initial limited search of MEDLINE and CINAHL databases was undertaken to identify key words contained in the title or abstract, and index terms used to describe relevant articles. A second extensive search was undertaken using all identified key words and index terms. The third step was a search of the reference lists and bibliographies of all relevant articles.

Methodological quality All identified studies that met the inclusion criteria were assessed for methodological validity by two reviewers prior to inclusion in the review. Critical appraisal of studies focused on identifying bias in selection, performance, attrition and detection.

Results This review found few studies of sufficient quality to meet the inclusion criteria. The included studies often utilised historical control groups, potentially confounding measurement of their outcomes. The outcome measures varied considerably, thus meta-analysis was not possible.

Conclusions This review suggests topical mupirocin may reduce the risk of exit-site infection; however, the clinical effectiveness of any one antibiotic, antiseptic or dressing procedure was not established for the prevention or reduction of exit-site infection rates or peritonitis. This review has underlined large gaps in the existing knowledge on the care of exit sites in patients on peritoneal dialysis.

目的本综述的目的是评价和综合现有的关于腹膜透析导管出口护理的临床效果的最佳证据。纳入标准:本综述纳入了所有评估腹膜出口护理有效性的随机对照试验。在没有随机对照试验的情况下,其他对照研究设计,如非随机对照试验,被考虑纳入叙述性总结,以确定当前的方法和可能的未来策略。研究对象为接受维持性腹膜透析的慢性肾功能衰竭的成年人。关注的干预措施是那些用于管理腹膜导管出口部位的干预措施,包括敷料的类型、敷料的频率、皮肤护理的类型以及局部防腐剂或抗菌剂的使用。搜索策略搜索旨在找到已发表和未发表的研究。对MEDLINE和CINAHL数据库进行初步有限搜索,以确定标题或摘要中包含的关键词,以及用于描述相关文章的索引术语。使用所有确定的关键字和索引项进行第二次广泛搜索。第三步是查找所有相关文章的参考书目和参考书目。方法学质量所有符合纳入标准的研究在纳入本综述前由两名审稿人评估方法学效度。对研究的批判性评价侧重于确定在选择、表现、损耗和检测方面的偏见。结果本综述发现很少有足够质量的研究符合纳入标准。纳入的研究通常使用历史对照组,这可能会混淆其结果的测量。结果测量差异很大,因此不可能进行meta分析。结论本综述提示外用莫匹罗星可降低手术部位外感染的风险;然而,任何一种抗生素、防腐剂或敷料程序在预防或减少手术部位外感染率或腹膜炎方面的临床效果尚未确定。这篇综述强调了在腹膜透析患者出口部位护理方面现有知识的巨大差距。
{"title":"Clinical effectiveness of different approaches to peritoneal dialysis catheter exit-site care","authors":"Craig Lockwood RN BN GradDip (ClinNurs) MNSC,&nbsp; Brent Hodgkinson MSc,&nbsp;Tamara Page RN BN HyperbaricNursCert GradDipNSc(HighDep)","doi":"10.1046/j.1479-697X.2003.00006.x","DOIUrl":"10.1046/j.1479-697X.2003.00006.x","url":null,"abstract":"<div>\u0000 \u0000 <p><b>Objective</b> The objective of this review was to appraise and synthesise the best available evidence on the clinical effectiveness of peritoneal dialysis catheter exit-site care.</p>\u0000 <p><b>Inclusion criteria</b> This review considered all randomised controlled trials that evaluated the effectiveness of peritoneal exit-site care. In the absence of randomised controlled trials, other controlled research designs such as non-randomised controlled trials were considered for inclusion in a narrative summary to enable the identification of current approaches and possible future strategies. Participants of interest were adults with chronic renal failure on maintenance peritoneal dialysis. Interventions of interest were those used to manage peritoneal catheter exit sites, and included types of dressings, frequency of dressings, types of skin care, and use of topical antiseptic or antimicrobial agents.</p>\u0000 <p><b>Search strategy</b> The search sought to find both published and unpublished studies. An initial limited search of MEDLINE and CINAHL databases was undertaken to identify key words contained in the title or abstract, and index terms used to describe relevant articles. A second extensive search was undertaken using all identified key words and index terms. The third step was a search of the reference lists and bibliographies of all relevant articles.</p>\u0000 <p><b>Methodological quality</b> All identified studies that met the inclusion criteria were assessed for methodological validity by two reviewers prior to inclusion in the review. Critical appraisal of studies focused on identifying bias in selection, performance, attrition and detection.</p>\u0000 <p><b>Results</b> This review found few studies of sufficient quality to meet the inclusion criteria. The included studies often utilised historical control groups, potentially confounding measurement of their outcomes. The outcome measures varied considerably, thus meta-analysis was not possible.</p>\u0000 <p><b>Conclusions</b> This review suggests topical mupirocin may reduce the risk of exit-site infection; however, the clinical effectiveness of any one antibiotic, antiseptic or dressing procedure was not established for the prevention or reduction of exit-site infection rates or peritonitis. This review has underlined large gaps in the existing knowledge on the care of exit sites in patients on peritoneal dialysis.</p>\u0000 </div>","PeriodicalId":100738,"journal":{"name":"JBI Reports","volume":"1 6","pages":"167-201"},"PeriodicalIF":0.0,"publicationDate":"2003-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1046/j.1479-697X.2003.00006.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77284017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Prevention and management of shoulder pain in the hemiplegic patient 偏瘫患者肩痛的预防与处理
Pub Date : 2003-09-16 DOI: 10.1046/j.1479-6988.2003.00005.x
Tamara Page RN BN GradDipNSc(HighDep), Craig Lockwood RN BN GradDipClinNurs MNSc

Objective The objective of this review was to summarise the best available research related to the prevention and management of shoulder pain in the hemiplegic patient.

Inclusion criteria This review considered all studies that included hemiplegic patients post-cerebral vascular accident (CVA). Interventions of interest were any treatments or programs used to manage or prevent shoulder pain secondary to hemiplegia. The primary outcomes of interest were those related to pain. This review considered any randomised controlled trials (RCT) that evaluated the effectiveness of interventions that addressed shoulder pain in hemiplegic patients. In the absence of RCT, other research designs such as non-randomised controlled trials, time series and case series were also considered for inclusion in a narrative summary.

Search strategy The search sought to find both published and unpublished studies. Databases were searched up to February 2002 and included Medline, CINAHL, Current Contents, Cochrane Library, Expanded Academic Index, Electronic Collections Online, Turning Research Into Practice (TRIP), Dissertation Abstracts and Proceedings First. The reference lists of all studies identified were searched for additional studies.

Assessment of methodological quality All studies were checked for methodological quality by two reviewers and data was extracted using a data extraction tool.

Results Current research evaluating the effectiveness of treatment interventions on hemiplegic shoulder pain is very limited. The studies were very diverse in their nature of research. There has been no replication of studies, with the studies found using different populations, interventions or outcome measures. Not one study could be compared with another. Meta-analysis was unable to be performed not only because of inadequate reporting of results, but more often due to differences between the studies’ participants and the range of interventions used. The diversity in interval post-CVA also makes it difficult to make any comparisons between studies. For this reason the review is in narrative form.

Conclusions With this limited evidence, no single intervention has been identified that offers a dramatic effect in terms of treating pain in the hemiplegic shoulder. There is potential for some benefits for the patient's functional and comfort status, thereby improving their quality of life and maximising their social participation.

Preventive interventions demonstrated that a shoulder positioning policy had no statistically significant effect on pain. Strapping within 48 h significantly delayed the onset of pain and current research evaluating exercise is not limited to just one area of exercise, but a diverse range, making it difficult to make any comparisons. Some studies did suggest evidence of improvement, al

目的本综述的目的是总结有关预防和治疗偏瘫患者肩痛的最佳研究。纳入标准:本综述纳入了所有涉及脑血管意外(CVA)后偏瘫患者的研究。感兴趣的干预措施是用于管理或预防偏瘫继发肩痛的任何治疗或计划。主要关注的结果是与疼痛相关的结果。本综述纳入了所有评估偏瘫患者肩部疼痛干预措施有效性的随机对照试验(RCT)。在没有随机对照试验的情况下,其他研究设计,如非随机对照试验、时间序列和病例序列,也被考虑纳入叙述性总结。搜索策略搜索旨在找到已发表和未发表的研究。检索到2002年2月的数据库,包括Medline、CINAHL、Current Contents、Cochrane Library、Expanded Academic Index、Electronic Collections Online、Turning Research Into Practice (TRIP)、Dissertation Abstracts and Proceedings First。检索所有研究的参考文献列表以寻找其他研究。所有研究的方法学质量均由两名审稿人进行检查,并使用数据提取工具提取数据。结果目前评价偏瘫肩痛治疗干预措施有效性的研究非常有限。这些研究在研究性质上是非常多样化的。由于这些研究使用了不同的人群、干预措施或结果衡量标准,因此没有重复的研究。没有一项研究可以与另一项进行比较。荟萃分析无法进行,不仅是因为结果报告不充分,更常见的是由于研究参与者和使用的干预措施范围之间的差异。cva后间隔的多样性也使得研究之间难以进行比较。由于这个原因,这篇评论是叙事性的。在有限的证据下,没有一种单一的干预措施能够在治疗偏瘫肩关节疼痛方面产生显著的效果。对患者的功能和舒适状况有潜在的好处,从而改善他们的生活质量,最大限度地提高他们的社会参与。预防性干预表明肩部定位策略对疼痛没有统计学上的显著影响。在48小时内捆扎可以显著延缓疼痛的发作,目前评估运动的研究并不局限于运动的一个领域,而是一个不同的范围,这使得很难进行任何比较。一些研究确实提出了改善的证据,尽管有限。然而,一些运动技巧加重了肩痛。治疗干预表明,肌电生物反馈不能作为一种单独的治疗进行评估,因为它与放松疗法一起使用。在一项小型随机对照试验中,关节内注射曲安奈德尚未被证明是有益的,并且与高副作用发生率相关。不同的运动技术可能会加重肩痛(例如,与冷冻疗法相比,Bobath技术)。对功能性电刺激用于预防和治疗的有效性进行了系统评价,结论是目前没有证据表明有效果。
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引用次数: 23
Management of nipple pain and/or trauma associated with breast-feeding 与母乳喂养有关的乳头疼痛和/或创伤的处理
Pub Date : 2003-08-14 DOI: 10.1046/j.1479-697x.2003.00004.x
Tamara Page RN BN GradDipNSc(HighDep), Craig Lockwood RN BN GradDipClinNurs MNSc,  Kylie Guest RN BN GradDipNSc(Cardiac)

Executive summary

Objective

The objective of this systematic review was to present the best available evidence related to the management of nipple pain, post childbirth in breast-feeding women. The specific objective of the review was to determine the effectiveness of interventions used by and for breast-feeding women to prevent and/or reduce nipple pain and trauma.

Selection criteria

The review considered all studies that included women who breast-fed with or without painful or traumatised nipples of any aetiology post childbirth.

Interventions of interest were: (i) interventions aimed to prevent or reduce pain and/or trauma to nipples post commencement of breast-feeding; and (ii) treatments for painful or traumatised nipples post commencement of breast-feeding.

The primary outcomes of interest were those related to the prevention and treatment of nipple pain and/or trauma in women post childbirth, in terms of:

  • •Incidence and prevalence of nipple pain

  • •Pain intensity

  • •Incidence and prevalence of nipple trauma

  • •Healing rates of traumatised nipples

  • •Breast-feeding duration.

This review considered randomised-controlled trials (RCT) that evaluated the effectiveness of interventions and treatments associated with breast-feeding practices. In the absence of RCTs other research designs such as non-randomised controlled trials and before and after studies were considered for inclusion in a narrative summary to enable the identification of current practices and possible future strategies.

Search strategy

The search sought to find both published and unpublished studies in the English language. Databases were searched up to and including August 2002 and included MEDLINE, CINAHL, Current Contents, Cochrane Library, Expanded Academic Index, Electronic

目的本系统综述的目的是提供与母乳喂养妇女分娩后乳头疼痛管理有关的最佳现有证据。本综述的具体目的是确定母乳喂养妇女预防和/或减少乳头疼痛和创伤的干预措施的有效性。选择标准本综述纳入了所有的研究,包括有或没有分娩后任何原因的乳头疼痛或创伤的母乳喂养的妇女。感兴趣的干预措施有:(i)旨在预防或减少母乳喂养开始后乳头疼痛和/或创伤的干预措施;以及(ii)母乳喂养开始后乳头疼痛或创伤的治疗。主要研究结果与预防和治疗分娩后女性乳头疼痛和/或创伤有关,包括:•乳头疼痛的发生率和流行度•疼痛强度•乳头创伤的发生率和流行度•创伤乳头的治愈率•母乳喂养时间。本综述考虑了随机对照试验(RCT),这些试验评估了与母乳喂养相关的干预和治疗的有效性。在没有随机对照试验的情况下,其他研究设计,如非随机对照试验和研究前后,被考虑纳入叙述性总结,以确定当前的做法和可能的未来策略。搜索策略搜索旨在找到已发表和未发表的英语研究。检索截止到2002年8月的数据库,包括MEDLINE、CINAHL、Current Contents、Cochrane Library、扩展学术索引、在线电子馆藏、将研究转化为实践(TRIP)、澳大利亚母乳喂养协会哺乳资源中心、论文摘要和论文集First。在所有确定的研究的参考文献列表中搜索其他研究。所有研究的方法学质量均由两名审稿人进行检查,并使用数据提取工具提取数据。结果有大量的研究评估了用于预防或治疗母乳喂养妇女乳头疼痛或创伤的许多干预措施的有效性。大多数研究在样本人口统计、评估的干预措施和评估的结果方面都是异质的。由于这个原因,大部分的综述都是叙述性的,通过meta-view图表来呈现更具统计学意义的结果。在教育课程中向母乳喂养妇女提供一致的信息将有助于确定哪种教学最有效;然而,研究中提供了不同的教育信息,或者没有详细说明实际提供了什么教育。本综述中的许多随机对照试验基于小样本量和特定的社会文化背景。小样本量限制了可靠概括发现的能力,因为存在假阳性结果的风险。此外,在某些情况下,研究没有达到统计意义,尽管如果使用更大的样本量可能会达到统计意义。这些是与随机对照试验相关的常见局限性。本综述的作者建议在实施综述建议之前充分考虑样本量和研究环境,以确定对不同临床环境的适用性。结果部分强调了每个纳入研究的样本量问题。在有限的证据下,没有一个单一的干预措施能够在治疗母乳喂养妇女的疼痛和/或创伤方面产生显著的效果。 然而,有一些潜在的好处,可以减少疼痛和增加舒适度,从而最大限度地延长母乳喂养的时间。结论在预防方面,建议采用温水敷乳预防乳头疼痛,单纯保持乳头清洁干燥预防乳头破裂。在治疗方面,建议用温水敷敷来减轻乳头疼痛,并且分泌母乳可以减少乳头破裂的持续时间。水凝胶敷料与感染的高发生率相关,不推荐使用。如果金黄色葡萄球菌培养呈阳性,建议使用全身抗生素。对母乳喂养的妇女进行关于婴儿的体位和附着在乳房上的教育,需要进一步的研究来评估它是否更有效地预防乳头疼痛和/或创伤。温水敷乳治疗乳头疼痛的有效性有待进一步研究。建议研究充血、安抚奶嘴和奶瓶对乳头疼痛和/或创伤的影响。对许多研究中使用的干预措施进行进一步调查,可以一次使用一种干预措施,与不进行治疗相比。具体的研究重点应包括随机对照试验,以评估:(i)与未治疗相比,羊毛脂;(ii)与未处理相比,羊毛脂和贝壳;(三)表示母乳与未治疗相比。
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引用次数: 32
Filling the gaps: identifying nursing research priorities through the analysis of completed systematic reviews† 填补空白:通过分析已完成的系统综述,确定护理研究重点
Pub Date : 2003-07-07 DOI: 10.1046/j.1479-6988.2003.00003.x
Andrea Averis RN RM BSc MSc(PHC) PhD FRCNA FGLF, Alan Pearson RN PhD FRCNA FRCN

Background This report describes the results of a study designed to identify research priorities in nursing arising out of the analysis of 22 systematic review reports published by the Joanna Briggs Institute (JBI) from 1998 to 2002. A feature of the systematic review of evidence is the noticeable lack of high-quality evidence to support a large proportion of nursing interventions and activities. Systematic review topics are selected as areas of concern about practice by nurses comprising the individual and corporate membership of JBI at Professional Advisory Forums and meetings held annually throughout Australia and internationally in conjunction with JBI's collaborating centres. Such selection prioritises nurses’ views about what ‘matters in their daily practice’.

Objective and Methods The study comprised a content analysis of the 22 systematic review reports and set out to:

  • • identify any striking gaps in evidence for frequently used practices;

  • • generate research questions to address the gaps; and

  • • suggest research approaches appropriate to the research questions generated.

Results The results of the analysis identified in excess of 200 important gaps in the evidence base available for nursing practice in relation to the 22 discrete areas of practice examined. Recommendations included the wide dissemination of this report to promote the results of systematic reviews as an important resource in setting research priorities. Policy makers, the Commonwealth Government, State and Territory Governments, research funding bodies, organisations and individuals involved in decision-making and the funding of research in health care have received little substantive direction in setting priorities for nursing research. This lack of well founded advice is evidenced by the incredibly low level of support for nursing research in Australia and the large number of gaps in evidence for nursing practice.

Conclusions Knowledge transfer – of evidence into practice – has the potential to improve health outcomes, but the delivery of ‘best practice’ care based on sound evidence is dependant upon the generation of evidence to fill systematically identified gaps.

本报告描述了一项研究的结果,该研究旨在通过分析乔安娜布里格斯研究所(JBI)从1998年到2002年发表的22份系统评价报告,确定护理领域的研究重点。证据系统评价的一个特点是明显缺乏高质量的证据来支持大部分护理干预措施和活动。在专业咨询论坛和会议上,由JBI的个人和公司成员组成的护士选择了系统的审查主题,作为他们关注的实践领域,这些论坛和会议每年在澳大利亚举行,并与JBI的合作中心一起举行。这种选择优先考虑护士对“日常实践中重要的事情”的看法。目的和方法本研究包括对22份系统评价报告的内容分析,旨在:•确定常用做法证据中的任何显著差距;•产生研究问题,以解决差距;提出适合研究问题的研究方法。结果分析的结果确定了超过200个重要的空白证据基础可用于护理实践相关的22个离散领域的实践检查。建议包括广泛传播本报告,以促进系统审查的结果,将其作为确定研究优先事项的重要资源。决策者、联邦政府、州和地区政府、研究资助机构、参与保健研究决策和资助的组织和个人在确定护理研究优先事项方面几乎没有得到实质性的指导。澳大利亚对护理研究的支持水平低得令人难以置信,护理实践的证据也存在大量差距,这证明了这种缺乏充分依据的建议。知识转移——将证据转化为实践——具有改善卫生结果的潜力,但是基于可靠证据提供“最佳实践”护理取决于产生证据来填补系统地确定的空白。
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引用次数: 26
Effectiveness of a multidisciplinary total parenteral nutrition team in the hospital setting 多学科全肠外营养小组在医院环境中的有效性
Pub Date : 2003-06-24 DOI: 10.1046/j.1479-6988.2003.00002.x
Ritin Fernandez RN BSc(Nurs) MN(CritCare), Rhonda Griffiths RN CM BEd(Nurs) MSc(Hons) DrPH,  Carlie-Jane Naylor BSc MNutrDiet MPH

Background Total parenteral nutrition (TPN) is a form of nutritional support that has become an essential adjunct to the management of patients who are unable to obtain adequate nutrition either via the oral or enteral route. Previous studies indicate that TPN can be administered safely and effectively to patients; however, there are associated risks with this form of nutritional support. Researchers have indicated that due to the complexity of TPN therapy a high level of knowledge and expertise is required in the management of these patients. The multidisciplinary team approach has been supported for its ability to assess the patients’ nutritional status, prescribe the nutritional requirements, and reduce the incidence of metabolic complications through regular monitoring. However, contradictory views on the effectiveness of multidisciplinary TPN teams in health-care facilities have also been reported.

Aim The aim of this review was to critically analyse the literature and present the best available evidence that investigated the effectiveness of multidisciplinary TPN teams in the provision of TPN to adult hospitalised patients. The primary outcomes included: incidence of catheter-related complications, types of catheter-related complications, incidence of metabolic and electrolyte abnormalities, provision of nutritional requirements, estimated nutritional requirements, number of patients whose nutritional goals were met and the amount of energy and protein provided. Secondary outcomes included cost effectiveness of nutritional support teams and physician compliance with team recommendations.

Search strategy The literature search sought to identify both published and unpublished studies utilising various search strategies and the Internet. The Cochrane Library (2001, Issue 4) was initially searched to identify randomised controlled trials. The other electronic databases searched included CINAHL, Complete Medline, Complete Biomedical Collection, Complete Nursing Collection, and EMBASE. Experts and company representatives were contacted to identify published reports as well as research in progress relevant to this review. Professional bodies were contacted and included the British Association for Parenteral and Enteral Nutrition (BAPEN) and the Australasian Society for Parenteral and Enteral Nutrition (AuSPEN).

Selection criteria All randomised and non-randomised controlled trials comparing the effectiveness of multidisciplinary TPN teams, in the provision of TPN to adult hospitalised patients, were considered for inclusion in this review. Trials were included if they reported objective or subjective measures of nutritional, metabolic and catheter-related complications and cost effectiveness. To minimise publication bias studies reported in other languages were also considered for inclusion in the review.

Data collection a

关于TPN组在减少电解质和代谢异常方面的益处的相互矛盾的结果表明,需要进一步的研究来阐明TPN组对这一结果的影响。当由TPN团队管理时,患者估计的能量需求的提供受到积极影响;然而,有关TPN团队在提供蛋白质需求方面的有效性的证据仍不清楚。从这篇综述来看,尚不清楚TPN团队对患者的管理是否阻止了TPN的不当使用。从研究中获得的有限数据提供了在成本效益方面组间临床重要差异的证据。
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引用次数: 6
Comparison of late night and early morning removal of short-term urethral catheters 深夜与清晨短时导尿管拔除的比较
Pub Date : 2003-05-22 DOI: 10.1046/j.1479-6988.2003.00001.x
Ritin Fernandez RN MN(CritCare),  Rhonda Griffiths RN CM BEd(Nurs) MSc(Hons) DrPH,  Penny Murie RN

Background Indwelling urethral catheters (IUCs) are inserted in approximately 15–25% of all hospitalised patients mainly to assist clinicians to accurately monitor urine output during acute illness or following surgery, to treat urinary retention and for investigative purposes. However, this procedure is associated with significant morbidity. Although research has focused on the type and maintenance of urinary catheters and techniques for insertion, limited attention has been given to the procedures for their removal, in particular whether the time of day the IUC is removed influences patient outcomes. There is no consensus among clinicians about the optimal time for removal of IUCs, rather practices tend to be based on personal preference and tradition rather than on evidence from research.

Objectives The objective of this review was to determine whether the timing of the removal of IUCs influences patient outcomes. The primary outcomes of interest included duration to and volume of first void; length of hospitalisation; number of patients developing urinary retention and number requiring recatheterisation. Secondary outcome measures included patient satisfaction and the percentage of IUCs removed according to the scheduled time for removal.

Search strategy A literature search was performed using the following databases Medline (1966–2000), CINAHL (1982–2002), Nursing Collection (1995–2002), EMBASE (1980-current) and the Cochrane Controlled Trials Register (Issue 2, 2002 of Cochrane Library). In addition, the reference lists of relevant trials and conference proceedings were also scrutinised. No language restrictions were applied. Company representatives, experts and investigators were contacted to elicit further information.

Selection criteria All published and unpublished randomised and quasi-randomised controlled trials that compared the effects of the timing of removal of short-term IUC on patient outcomes were considered for inclusion in the review. Trials were included if they reported objective measures of time to and volume of the first void, length of hospital stay (number of hours from removal of the IUC to discharge), the number of patients who developed urinary retention following the removal of the IUC and the incidence of recatheterisation. Trials that included subjective measures of patient satisfaction were also considered for inclusion in the review.

Data collection and analysis Eligibility of the trials for inclusion in the review, details of eligible trials and the methodological quality of the trials was assessed independently by two reviewers. All information was verified by a third reviewer. Odds ratios for dichotomous data and weighted mean differences for continuous data were calculated with 95% confidence intervals. Where synthesis was inappropriate a narrative overview was undertaken. Trial

背景:大约15-25%的住院患者插入了留置导尿管(IUCs),主要是为了帮助临床医生在急性疾病期间或手术后准确监测尿量,治疗尿潴留和用于调查目的。然而,该手术与显著的发病率相关。虽然研究的重点是导尿管的类型和维护以及插入技术,但对其取出程序的关注有限,特别是取出IUC的时间是否会影响患者的预后。临床医生对取出IUCs的最佳时间没有共识,而是基于个人偏好和传统,而不是基于研究证据。本综述的目的是确定摘除IUCs的时机是否会影响患者的预后。关注的主要结果包括第一次无效的持续时间和数量;住院时间;发生尿潴留的患者数量和需要再导尿的患者数量。次要结局指标包括患者满意度和按计划时间取出IUCs的百分比。使用以下数据库进行文献检索:Medline(1966-2000)、CINAHL(1982-2002)、Nursing Collection(1995-2002)、EMBASE(1980-至今)和Cochrane对照试验登记册(Cochrane Library 2002年第2期)。此外,还仔细审查了有关试验和会议记录的参考清单。没有语言限制。我们联系了公司代表、专家和调查人员,以获得进一步的信息。所有比较短期IUC取出时间对患者预后影响的已发表和未发表的随机和准随机对照试验均被纳入本综述。如果试验报告了第一次排尿的时间和体积、住院时间(从取出IUC到出院的小时数)、取出IUC后出现尿潴留的患者人数和再导尿管发生率的客观测量,则纳入试验。包括患者满意度主观测量的试验也被纳入本综述。资料收集和分析纳入本综述的试验的资格、符合条件的试验的细节和试验的方法学质量由两位审稿人独立评估。所有信息均由第三位审稿人核实。以95%置信区间计算二分类数据的优势比和连续数据的加权平均差异。如果综合不适当,则进行叙述性概述。试验按手术类型分组。结果8项比较清晨和深夜取出IUCs有效性的随机对照试验符合本综述。四项试验(三项是泌尿外科手术和程序后的试验,一项是妇科手术后的试验)表明,深夜取出IUCs的患者与早上取出IUCs的患者相比,第一个空洞的体积在统计学上有显著增加。在经尿道前列腺切除术(TURP)患者的两项试验中,第一腔的体积没有统计学上的显著差异。一项涉及妇科手术患者的试验报告称,午夜取出IUC(中位3小时20分钟)比清晨(中位5小时)首次排空时间更短(P = 0.012)。对泌尿外科手术和手术后患者进行的三项试验报告称,在午夜取出IUCs的患者比在早上取出IUCs的患者第一次排空时间更长,这三项试验都显示了统计学上的显著差异。在上午取出iucp后,首次排空时间缩短,尽管这些结果没有统计学意义。在午夜取出IUC的患者出院时间明显早于在早上取出IUC的患者(P < 0.00001),这将为医院节省潜在的成本。结论:基于有限的现有证据,本综述提示在午夜取出IUCs后患者预后和住院时间缩短方面有益处。应在更广泛的环境和特定的患者群体中进行进一步的试验,以提高普遍性。试验还应检查午夜或清晨取出IUC与一天中任何时间取出相比的疗效。
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引用次数: 12
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