Pub Date : 2017-04-01DOI: 10.24816/JCGG.2017.V8I1.04
D. Rasheedy, M. Refaee, Ghada Farag, Samia Abdelrehem, S. Pessar
Background: Dehydroepiandrosterone (DHEA) is believed to be protective against articular cartilage injury and it is widely used as one of the natural remedies for inflammatory and degenerative arthritis. Yet, information about the association between DHEA level and knee OA is lacking. Objectives: To explore the link between serum dehydroepiandrosterone sulfate (DHEAs) levels and knee OA among elderly patients. Methods: A case control study was conducted on 80 elderly subjects (40 males, 40 females) aged 60 years and older attending the outpatient clinics in Ain Shams University Hospital. Participants underwent a standard clinical examination of the knee, assessment of physical difficulty and pain severity using WOMAC OA index. Weight-bearing anteroposterior radiographs of the knees in the semi-flexed position were performed. Serum levels of DHEAs were examined. Results: The serum level of DHEAs in males with knee OA was 0.29 ± 0.17 μg/mL compared to those without knee OA 0.59 ± 0.51 μg/mL (p=0.006), small but significant difference existed between the serum level of DHEAs in females with knee OA 0.25 ± 0.11 μg/mL compared to those without knee OA 0.39 ± 0.26 μg/mL (p=0.044*). Additionally, the serum DHEAs level negatively correlated with the severity of knee OA in both sexes. Conclusions: There was a sex difference in serum DHEAs level and occurrence of knee OA. Lower levels of DHEAs were reported in elderly with knee OA and the serum DHEAs level negatively correlated with the severity of knee OA.
{"title":"Dehydroepiandrosterone sulfate level and knee osteoarthritis in older adults: preliminary data for the possible link","authors":"D. Rasheedy, M. Refaee, Ghada Farag, Samia Abdelrehem, S. Pessar","doi":"10.24816/JCGG.2017.V8I1.04","DOIUrl":"https://doi.org/10.24816/JCGG.2017.V8I1.04","url":null,"abstract":"Background: Dehydroepiandrosterone (DHEA) is believed to be protective against articular cartilage injury and it is widely used as one of the natural remedies for inflammatory and degenerative arthritis. Yet, information about the association between DHEA level and knee OA is lacking. Objectives: To explore the link between serum dehydroepiandrosterone sulfate (DHEAs) levels and knee OA among elderly patients. Methods: A case control study was conducted on 80 elderly subjects (40 males, 40 females) aged 60 years and older attending the outpatient clinics in Ain Shams University Hospital. Participants underwent a standard clinical examination of the knee, assessment of physical difficulty and pain severity using WOMAC OA index. Weight-bearing anteroposterior radiographs of the knees in the semi-flexed position were performed. Serum levels of DHEAs were examined. Results: The serum level of DHEAs in males with knee OA was 0.29 ± 0.17 μg/mL compared to those without knee OA 0.59 ± 0.51 μg/mL (p=0.006), small but significant difference existed between the serum level of DHEAs in females with knee OA 0.25 ± 0.11 μg/mL compared to those without knee OA 0.39 ± 0.26 μg/mL (p=0.044*). Additionally, the serum DHEAs level negatively correlated with the severity of knee OA in both sexes. Conclusions: There was a sex difference in serum DHEAs level and occurrence of knee OA. Lower levels of DHEAs were reported in elderly with knee OA and the serum DHEAs level negatively correlated with the severity of knee OA.","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85288290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-01DOI: 10.24816/jcgg.2017.v8i1.07
T. Kanie, T. Higuchi, Ryosuke Koyamada, M. Suda, Sadamu Okada
An 86-year-old Japanese woman presented with severe anemia and was diagnosed as mixed-type autoimmune hemolytic anemia (AIHA). Subsequently, although she did not show typical manifestations of systemic lupus erythematosus (SLE), she was diagnosed as SLE complicated with Sjögren's syndrome and Greves’ disease. While AIHA occurs in 5-10% of SLE patients and SLE is the most common underlying condition of mixed-type AIHA, complication of mixed-type AIHA among SLE patients has not been studied yet. SLE mainly affects women of child-bearing age and is seldom diagnosed in elderlies and the present case is the oldest SLE patient presented with mixed type-AIHA reported so far in the literature, indicating that mixed-type AIHA may complicate in elderly SLE patients and thorough evaluation of the possibility of the complication is justified. She also exemplifies the notion that elderly SLE patients often present with manifestations different from those in younger patients.
{"title":"Very elderly-onset systemic lupus erythematosus presented with mixed-type autoimmune hemolytic anemia","authors":"T. Kanie, T. Higuchi, Ryosuke Koyamada, M. Suda, Sadamu Okada","doi":"10.24816/jcgg.2017.v8i1.07","DOIUrl":"https://doi.org/10.24816/jcgg.2017.v8i1.07","url":null,"abstract":"An 86-year-old Japanese woman presented with severe anemia and was diagnosed as mixed-type autoimmune hemolytic anemia (AIHA). Subsequently, although she did not show typical manifestations of systemic lupus erythematosus (SLE), she was diagnosed as SLE complicated with Sjögren's syndrome and Greves’ disease. While AIHA occurs in 5-10% of SLE patients and SLE is the most common underlying condition of mixed-type AIHA, complication of mixed-type AIHA among SLE patients has not been studied yet. SLE mainly affects women of child-bearing age and is seldom diagnosed in elderlies and the present case is the oldest SLE patient presented with mixed type-AIHA reported so far in the literature, indicating that mixed-type AIHA may complicate in elderly SLE patients and thorough evaluation of the possibility of the complication is justified. She also exemplifies the notion that elderly SLE patients often present with manifestations different from those in younger patients.","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90693495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-01DOI: 10.24816/JCGG.2017.V8I1.05
M. D’Andrea, Kesava Reddy
Objectives: To evaluate the health risks associated with benzene exposure in elderly subjects following a flaring disaster at the BP refinery in Texas City, Texas. Methods: Elderly subjects aged 60 years and older who had been exposed and unexposed to benzene were included. We reviewed medical charts and compared measures of white blood cells (WBC), platelets, hemoglobin, hematocrit, blood urea nitrogen (BUN), creatinine, alkaline phosphatase (ALP), aspartate amino transferase (AST), and alanine amino transferase (ALT) in exposed and unexposed elderly subjects. Results: Records from 294 elderly subjects (benzene exposed, n=216 and unexposed, n=78) were reviewed. Benzene exposed subjects had significantly higher levels of WBC (X 103 per μL) (7.7±1.9 versus 6.3±1.5, P=0.0000) and platelet (X 103 per μL) counts (256.8 ± 51.6 versus 237.9 ± 41.9, P=0.0104) compared with the unexposed subjects. Serum creatinine levels (mg/dL) were also significantly increased in the exposed group compared with the unexposed group (1.1 ± 0.4 versus 0.9±0.2, P=0.000). Serum levels of ALP (IU/L) were significantly elevated in the exposed subjects compared with the unexposed subjects (87.5 ± 23.6 versus 72.5 ± 17.8, P=0.000). Similarly, benzene exposed subjects had significantly higher levels of AST (24.8 ± 6.2 versus 19.2 ± 5.1, IU/L, P=0.000) and ALT (24.2 ± 8.6 versus 19.1 ± 4.8, IU/L, P=0.000) compared with those unexposed to benzene. Conclusions: Benzene exposure resulted in significant alterations in hematological and hepatic profiles among elderly subjects.
目的:评估在德克萨斯州德克萨斯市BP炼油厂发生燃烧灾难后，老年人苯暴露相关的健康风险。方法:选取60岁及以上接触和未接触苯的老年人为研究对象。我们回顾了医学图表，并比较了暴露和未暴露的老年人的白细胞(WBC)、血小板、血红蛋白、红细胞压积、血尿素氮(BUN)、肌酐、碱性磷酸酶(ALP)、天冬氨酸氨基转移酶(AST)和丙氨酸氨基转移酶(ALT)的测量。结果:回顾了294例老年受试者(苯暴露者216例，未暴露者78例)的记录。苯暴露组WBC (X 103 / μL)(7.7±1.9比6.3±1.5,P=0.0000)和血小板(X 103 / μL)计数(256.8±51.6比237.9±41.9,P=0.0104)明显高于未暴露组。与未暴露组相比，暴露组血清肌酐水平(mg/dL)显著升高(1.1±0.4 vs 0.9±0.2,P=0.000)。与未暴露者相比，暴露者血清ALP (IU/L)水平显著升高(87.5±23.6 vs 72.5±17.8,P=0.000)。同样，苯暴露组的AST(24.8±6.2比19.2±5.1,IU/L, P=0.000)和ALT(24.2±8.6比19.1±4.8,IU/L, P=0.000)水平显著高于未暴露组。结论:苯暴露导致老年人血液学和肝脏特征的显著改变。
{"title":"Organ Toxicity from Benzene Exposure among Elderly Subjects after a Flaring Disaster at the BP Refinery Plant in Texas City","authors":"M. D’Andrea, Kesava Reddy","doi":"10.24816/JCGG.2017.V8I1.05","DOIUrl":"https://doi.org/10.24816/JCGG.2017.V8I1.05","url":null,"abstract":"Objectives: To evaluate the health risks associated with benzene exposure in elderly subjects following a flaring disaster at the BP refinery in Texas City, Texas. Methods: Elderly subjects aged 60 years and older who had been exposed and unexposed to benzene were included. We reviewed medical charts and compared measures of white blood cells (WBC), platelets, hemoglobin, hematocrit, blood urea nitrogen (BUN), creatinine, alkaline phosphatase (ALP), aspartate amino transferase (AST), and alanine amino transferase (ALT) in exposed and unexposed elderly subjects. Results: Records from 294 elderly subjects (benzene exposed, n=216 and unexposed, n=78) were reviewed. Benzene exposed subjects had significantly higher levels of WBC (X 103 per μL) (7.7±1.9 versus 6.3±1.5, P=0.0000) and platelet (X 103 per μL) counts (256.8 ± 51.6 versus 237.9 ± 41.9, P=0.0104) compared with the unexposed subjects. Serum creatinine levels (mg/dL) were also significantly increased in the exposed group compared with the unexposed group (1.1 ± 0.4 versus 0.9±0.2, P=0.000). Serum levels of ALP (IU/L) were significantly elevated in the exposed subjects compared with the unexposed subjects (87.5 ± 23.6 versus 72.5 ± 17.8, P=0.000). Similarly, benzene exposed subjects had significantly higher levels of AST (24.8 ± 6.2 versus 19.2 ± 5.1, IU/L, P=0.000) and ALT (24.2 ± 8.6 versus 19.1 ± 4.8, IU/L, P=0.000) compared with those unexposed to benzene. Conclusions: Benzene exposure resulted in significant alterations in hematological and hepatic profiles among elderly subjects.","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89580639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-01DOI: 10.24816/JCGG.2017.V8I1.01
S. Chand
Behavioral and psychological symptoms of dementia (BPSD) lead to functional impairment in patients with dementia and caregiver distress. Non-pharmacological treatments of BPSD have gained increasing attention since the use of pharmacological methods has been found to be associated with negative consequences and risks. Behavioral management of BPSD is one of the non-pharmacological treatment approaches that has been utilized in psychosocial treatment programs. Behavioral strategies have also been used in the treatment of caregiver distress and depression. This paper is based on a comprehensive search of literature in PubMed/MEDLINE and Scopus. It reviews the literature to evaluate the efficacy and utility of behavior management in helping with reduction of problem behaviors along with psychological distress in caregivers of patients with dementia. Evidence indicates that despite limitations in the studies, incorporation of behavioral management strategies into the care of patients with dementia is beneficial to caregivers as well as dementia patients.
{"title":"Behavior management: It's impact on dementia patients and caregivers","authors":"S. Chand","doi":"10.24816/JCGG.2017.V8I1.01","DOIUrl":"https://doi.org/10.24816/JCGG.2017.V8I1.01","url":null,"abstract":"Behavioral and psychological symptoms of dementia (BPSD) lead to functional impairment in patients with dementia and caregiver distress. Non-pharmacological treatments of BPSD have gained increasing attention since the use of pharmacological methods has been found to be associated with negative consequences and risks. Behavioral management of BPSD is one of the non-pharmacological treatment approaches that has been utilized in psychosocial treatment programs. Behavioral strategies have also been used in the treatment of caregiver distress and depression. This paper is based on a comprehensive search of literature in PubMed/MEDLINE and Scopus. It reviews the literature to evaluate the efficacy and utility of behavior management in helping with reduction of problem behaviors along with psychological distress in caregivers of patients with dementia. Evidence indicates that despite limitations in the studies, incorporation of behavioral management strategies into the care of patients with dementia is beneficial to caregivers as well as dementia patients.","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83784737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-03-01DOI: 10.24816/JCGG.2017.V8I1.06
Rohida Saleh Hudin, S. Shahar, Norhayati Ibrahim, Hanis Mastura Yahaya
Background/Purpose: Older adults are at high risk of food insecurity and malnutrition. However, the magnitude of food insecurity and malnutrition and their associations with socio-economic and psychosocial factors among older adults especially in rural areas of Malaysia are yet to be discovered. Therefore, this study aimed to determine the association between socio-economic and psychosocial factors with food insecurity and among older adults people in a rural area of Malaysia, i.e. an agricultural settlement under the Felda Land Development Authority (FELDA).
{"title":"Influence of socio-economic and psychosocial factors on food insecurity and nutritional status of older adults in felda settlement in malaysia","authors":"Rohida Saleh Hudin, S. Shahar, Norhayati Ibrahim, Hanis Mastura Yahaya","doi":"10.24816/JCGG.2017.V8I1.06","DOIUrl":"https://doi.org/10.24816/JCGG.2017.V8I1.06","url":null,"abstract":"Background/Purpose: Older adults are at high risk of food insecurity and malnutrition. However, the magnitude of food insecurity and malnutrition and their associations with socio-economic and psychosocial factors among older adults especially in rural areas of Malaysia are yet to be discovered. Therefore, this study aimed to determine the association between socio-economic and psychosocial factors with food insecurity and among older adults people in a rural area of Malaysia, i.e. an agricultural settlement under the Felda Land Development Authority (FELDA).","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"29 1","pages":"35-40"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82649946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-01DOI: 10.1016/J.JCGG.2016.04.003
K. Kosilov, S. Loparev, I. Kuzina, O. Shakirova, N. Zhuravskaya, Alexandra Lobodenko
{"title":"Factors of trospium treatment compliance among unemployed older persons","authors":"K. Kosilov, S. Loparev, I. Kuzina, O. Shakirova, N. Zhuravskaya, Alexandra Lobodenko","doi":"10.1016/J.JCGG.2016.04.003","DOIUrl":"https://doi.org/10.1016/J.JCGG.2016.04.003","url":null,"abstract":"","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"30 1","pages":"124-130"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87979058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-01DOI: 10.1016/J.JCGG.2015.11.002
D. Miu, S. Ling, C. Tse
{"title":"Epidemiology of vancomycin-resistant enterococci in postacute care facility and predictors of clearance: A 5-year retrospective cohort study","authors":"D. Miu, S. Ling, C. Tse","doi":"10.1016/J.JCGG.2015.11.002","DOIUrl":"https://doi.org/10.1016/J.JCGG.2015.11.002","url":null,"abstract":"","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"100 1","pages":"153-157"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90065844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-01DOI: 10.1016/J.JCGG.2016.01.001
Masayo Tanaka, F. Komura, A. Hanai, T. Tsuboyama, H. Arai
{"title":"Effects of Japanese drum exercise on depression and physical function in community-dwelling older women","authors":"Masayo Tanaka, F. Komura, A. Hanai, T. Tsuboyama, H. Arai","doi":"10.1016/J.JCGG.2016.01.001","DOIUrl":"https://doi.org/10.1016/J.JCGG.2016.01.001","url":null,"abstract":"","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"T155 1","pages":"158-163"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82647321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-01Epub Date: 2016-11-22DOI: 10.1016/S2210-8335(16)30064-8
{"title":"General Informatiom","authors":"","doi":"10.1016/S2210-8335(16)30064-8","DOIUrl":"https://doi.org/10.1016/S2210-8335(16)30064-8","url":null,"abstract":"","PeriodicalId":100764,"journal":{"name":"Journal of Clinical Gerontology and Geriatrics","volume":"7 4","pages":"Page iii"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S2210-8335(16)30064-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72245070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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