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Unusual lesions of the pancreas: A case series and review of the literature 胰腺异常病变:病例系列及文献回顾
Pub Date : 2025-11-01 Epub Date: 2025-09-22 DOI: 10.1016/j.sycrs.2025.100147
Kayla R. Widdowson , Max D. Hazeltine , Sebastian K. Chung , Lauren Scarpetti , Michelle Yang , James M. Lindberg
Lesions of the pancreas are commonly found, particularly with increased use of cross-sectional imaging. While there are a few well-described entities, atypical benign masses remain a diagnostic challenge and may mimic malignancy, leading to uncertainty in management. We present four cases of unusual, benign pancreatic lesions managed at a tertiary care center. While initially concerning for malignancy based on imaging and clinical presentation, these cases were ultimately diagnosed as a torsed ectopic splenule, lymphoepithelial cyst, benign simple mucinous cyst, and chronic mass-forming pancreatitis. Evaluation included imaging, endoscopic ultrasound, and tissue sampling. All patients underwent surgical resection, with final diagnoses confirmed through intraoperative findings and histopathology. A brief literature review was conducted for each entity to summarize distinguishing clinical, radiographic, and pathologic features. Further description of these atypical entities may help clinicians with appropriate diagnosis and guide treatment decisions.
胰腺病变是常见的,特别是随着横断面成像的使用增加。虽然有一些描述良好的实体,但非典型良性肿块仍然是诊断上的挑战,可能模仿恶性肿瘤,导致治疗的不确定性。我们提出了四个不寻常的病例,良性胰腺病变管理三级保健中心。这些病例最初根据影像学和临床表现考虑为恶性肿瘤,最终诊断为扭曲异位脾、淋巴上皮囊肿、良性单纯性粘液囊肿和慢性团块性胰腺炎。评估包括影像学、内窥镜超声和组织取样。所有患者均行手术切除,最终诊断通过术中发现和组织病理学证实。我们对每个实体进行了简短的文献回顾,以总结其临床、影像学和病理特征。对这些非典型实体的进一步描述可以帮助临床医生做出适当的诊断和指导治疗决策。
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引用次数: 0
Retro-sigmoid approach for an adult cerebellar hemangioblastoma with foramen magnum extension 乙状结肠后入路治疗伴枕骨大孔扩张的成人小脑血管母细胞瘤
Pub Date : 2025-11-01 Epub Date: 2025-07-03 DOI: 10.1016/j.sycrs.2025.100134
Ahmed Hafez Mousa , Badr Ahmed Abdul Hamid , Ayoub Ahmed Abedzadeh , Shaikh Sayeed Iqbal , Ayman Al-Sibaie , Abdulla Qassim , Ameer Alyeldien

Introduction

Cerebellar hemangioblastomas are rare, highly vascular tumors often associated with von Hippel-Lindau (VHL) disease. They typically arise in the cerebellar hemispheres and can affect the brain, spinal cord, and retina.

Case presentation

We report a case of a 36-year-old male presenting with persistent dizziness, initially misdiagnosed as peripheral vertigo. Neuroimaging revealed a right cerebellar mass with unusual extension through the foramen magnum, causing obstructive hydrocephalus. The patient underwent a right far-lateral suboccipital craniotomy. Gross total resection was achieved, and histopathology confirmed hemangioblastoma, with no evidence of VHL.

Conclusion

This case highlights an atypical presentation of cerebellar hemangioblastoma with foramen magnum extension. Surgical challenges in such cases can be mitigated by thorough preoperative planning, including angiography, detailed anatomical understanding, and refined microsurgical technique. Even without intraoperative neuromonitoring, complete resection without postoperative deficits is achievable. Further case reports are essential to enhance surgical strategies for rare tumor locations
小脑血管母细胞瘤是一种罕见的高度血管性肿瘤,常与von Hippel-Lindau (VHL)病相关。它们通常发生在小脑半球,可影响大脑、脊髓和视网膜。我们报告一位36岁男性,以持续头晕为主诉,最初误诊为周围性眩晕。神经影像学显示右侧小脑肿块异常延伸至枕骨大孔,引起梗阻性脑积水。患者接受了右远外侧枕下开颅手术。大体全切除,组织病理学证实为血管母细胞瘤,无VHL证据。结论本病例为不典型的小脑血管母细胞瘤伴枕骨大孔延伸。通过周密的术前计划,包括血管造影、详细的解剖理解和精细的显微外科技术,可以减轻这种情况下的手术挑战。即使没有术中神经监测,也可以实现无术后缺损的完全切除。进一步的病例报告是必要的,以提高手术策略的罕见肿瘤的位置
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引用次数: 0
Synchronous appendicitis and cholecystitis in the setting of intestinal malrotation: A rare presentation of adhesion of the appendix to the gallbladder 小肠旋转不良并发阑尾炎和胆囊炎:罕见的阑尾与胆囊粘连的表现
Pub Date : 2025-11-01 Epub Date: 2025-09-22 DOI: 10.1016/j.sycrs.2025.100146
Katie Lee , Hannah Woolley , Gregory Wu , Manuel Martinez

Introduction

Intestinal malrotation is a congenital abnormality that can complicate diagnosis of abdominal conditions. We present the first documented case of concurrent acute appendicitis, acute cholecystitis, and congenital intestinal malrotation.

Presentation of case

A 58-year-old female initially presented with perforated cholecystitis complicated by abscess formation and cholangitis, requiring interventional drainage and endoscopic stenting. Five months later, she returned with concurrent acute cholecystitis and appendicitis. Due to intestinal malrotation, the appendix was located in the right upper quadrant adjacent to the gallbladder and had eroded into the anterior abdominal wall. Laparoscopic subtotal cholecystectomy and appendectomy were successfully performed with pathology confirming both diagnoses.

Discussion

This case demonstrates a need for heightened suspicion of atypical presentations in patients with anatomical variants. Anatomical proximity may predispose to concurrent disease through bacterial spread.

Conclusion

This case reinforces the importance of maintaining broad differential diagnoses and utilizing comprehensive imaging in patients with anatomical variants.
肠道旋转不良是一种先天性异常,可使腹部疾病的诊断复杂化。我们提出了第一例并发急性阑尾炎、急性胆囊炎和先天性肠道旋转不良的病例。病例介绍:一名58岁女性,最初因穿孔性胆囊炎合并脓肿形成和胆管炎,需要介入引流和内镜下支架置入。5个月后,她复发并并发急性胆囊炎和阑尾炎。由于肠道旋转不良,阑尾位于右上象限,毗邻胆囊,并已侵蚀入前腹壁。腹腔镜胆囊次全切除术和阑尾切除术均成功,病理证实两种诊断。本病例表明,需要高度怀疑非典型表现的患者解剖变异。解剖上的接近可能通过细菌传播导致并发疾病。结论本病例强调了在解剖变异患者中保持广泛鉴别诊断和利用综合影像学的重要性。
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引用次数: 0
Surgical management of pulmonary mucormycosis caused by steroid-containing herbal supplements 含类固醇草药补品引起的肺毛霉菌病的外科治疗
Pub Date : 2025-11-01 Epub Date: 2025-07-01 DOI: 10.1016/j.sycrs.2025.100135
Claire Perez, Vikram Krishna, Federico Sertic, Raffaele Rocco, Andrew R. Brownlee, Harmik J. Soukiasian, Philicia Moonsamy
Pulmonary mucormycosis is a rare, life-threatening fungal infection that predominantly affects immunocompromised patients. Prompt diagnosis, antifungal therapy, and radical surgical intervention are essential to improve survival. We report a unique case of pulmonary mucormycosis in a 45-year-old diabetic man who had been taking an over-the-counter drug for joint and back pain that contains unregulated amounts of steroids. The patient presented with small-volume hemoptysis and was initially treated with antibiotics for cavitary pneumonia. A surgical wedge resection of the cavitary lesion revealed mucormycosis, and he was subsequently treated with amphotericin B. Despite these interventions, the infection rapidly progressed to encompass the entire right lung, and the patient required a right pneumonectomy to achieve source control. This case highlights the role of unregulated supplements as a risk factor for invasive fungal infections and the importance of considering pulmonary mucormycosis in patients who do not improve on antibiotics. Early recognition and aggressive surgical resection of all infected areas remains critical for favorable outcomes.
肺毛霉病是一种罕见的、危及生命的真菌感染,主要影响免疫功能低下的患者。及时诊断、抗真菌治疗和根治性手术干预对提高生存率至关重要。我们报告一个独特的病例肺毛霉菌病在一个45岁的糖尿病人谁一直服用非处方药的关节和背部疼痛,其中含有不规范的类固醇量。患者表现为小容量咯血,最初使用抗生素治疗空洞性肺炎。手术切除腔体病变发现有毛霉病,随后接受两性霉素b治疗,尽管采取了这些干预措施,但感染迅速发展到整个右肺,患者需要进行右全肺切除术以达到源头控制。该病例强调了不受管制的补品作为侵袭性真菌感染的危险因素的作用,以及在抗生素治疗无效的患者中考虑肺毛霉菌病的重要性。早期识别和积极手术切除所有感染区域仍然是取得良好结果的关键。
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引用次数: 0
Pediatric clival chordoma masquerading as meningioma: Diagnostic challenges and surgical considerations. A case report 伪装成脑膜瘤的儿童斜坡脊索瘤:诊断挑战和手术考虑。病例报告
Pub Date : 2025-11-01 Epub Date: 2025-09-22 DOI: 10.1016/j.sycrs.2025.100145
Diego Molina-Botello , Edgar Fernando Higuera-González , Zita Elizabeth Salazar-Ramírez , Roberto Casarrubias-Islas , Julio César López-Valdés
Pediatric clival chordomas are rare, malignant skull base tumors known for significant diagnostic and therapeutic challenges. We present a case of a 16-year-old male with progressive headaches and left sixth cranial nerve palsy whose clival mass was initially misdiagnosed as a meningioma by neuroimaging. Intraoperative findings and subsequent histopathology, however, confirmed a conventional chordoma (characterized by physaliferous cells, immunopositivity for cytokeratin, EMA, and S100, with a Ki-67 index of 5–10 %). This case underscores that pediatric clival chordomas can mimic more common lesions, emphasizing the critical role of early, accurate histopathological evaluation and a personalized multidisciplinary strategy for optimizing long-term patient outcomes.
小儿斜坡脊索瘤是一种罕见的恶性颅底肿瘤,诊断和治疗具有重大挑战。我们报告一个16岁的男性,他有进行性头痛和左第六脑神经麻痹,他的斜坡肿块最初被神经影像学误诊为脑膜瘤。然而,术中发现和随后的组织病理学证实为常规脊索瘤(以物理细胞为特征,细胞角蛋白、EMA和S100免疫阳性,Ki-67指数为5-10 %)。该病例强调了儿童斜坡脊索瘤可以模仿更常见的病变,强调了早期,准确的组织病理学评估和个性化多学科策略对优化患者长期预后的关键作用。
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引用次数: 0
Single chimney for elective endovascular treatment of juxtarenal abdominal aortic aneurysm with favorable asymmetric origin of the renal arteries. Is still valid in the custom-made device’s era? 单导管选择性血管内治疗肾动脉起源不对称的肾旁腹主动脉瘤。在定制设备的时代仍然有效吗?
Pub Date : 2025-11-01 Epub Date: 2025-07-14 DOI: 10.1016/j.sycrs.2025.100136
Diego Soto V , Cristian Marín O, Gabriel Cassorla J
Chimney endovascular aortic repair (ChEVAR) is a useful endovascular alternative for treating juxtarenal abdominal aortic aneurysms (AAA), particularly in cases with favorable anatomy. Case: 75-year-old male with a juxtarenal AAA involving the left renal artery. A successful ChEVAR procedure was performed using a parallel covered stent to preserve the left renal artery and achieve an adequate proximal seal. The postoperative course was favorable, with no complications or renal function deterioration. At the 20-month follow-up, computerized tomography angiography showed no signs of endoleak, a patent renal stent and a decrease in aneurysm sac size. Conclusion: ChEVAR is a feasible option for juxtarenal aneurysms when custom-made devices are unavailable, showing comparable mid- and long-term results. However, careful patient selection is essential to minimize risks such as endoleaks or stent thrombosis.
烟囱血管内主动脉修复术(ChEVAR)是治疗肾旁腹主动脉瘤(AAA)的一种有效的血管内替代方法,特别是在解剖结构良好的病例中。病例:75岁男性,肾旁AAA累及左肾动脉。我们成功地使用平行覆盖支架进行了ChEVAR手术,以保护左肾动脉并获得足够的近端封闭。术后过程良好,无并发症或肾功能恶化。在20个月的随访中,计算机断层血管造影显示无内漏迹象,肾支架通畅,动脉瘤囊变小。结论:在没有定制装置的情况下,ChEVAR是治疗关节旁动脉瘤的可行选择,其中期和长期效果相当。然而,谨慎的患者选择是必要的,以尽量减少风险,如内漏或支架血栓形成。
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引用次数: 0
Postpartum intracerebral and intraventricular hemorrhage – A case report and review of the literature 产后脑室内出血1例报告及文献复习
Pub Date : 2025-11-01 Epub Date: 2025-07-21 DOI: 10.1016/j.sycrs.2025.100142
Nikita Grace Mathews , Andrea Cuschieri , Mazhar Darwazeh , Adel Al Sisi , Kavita Krishnan , Rami Darwazeh

Background

Postpartum intracerebral hemorrhages (ICH) and intraventricular hemorrhages (IVH) are rare but potentially life-threatening conditions. They are often precipitated by hypertensive disorders, such as preeclampsia. Thus, the peripartum period is a critical time for monitoring female patients, particularly those at risk of hypertensive emergencies.

Clinical presentation

A 32-year-old female with no previous history of hypertension presented with severe headaches and elevated blood pressure (197/104 mmHg) seven days after delivery. Immediate brain computed tomography (CT) scan revealed the presence of a large ICH and IVH involving all 4 ventricles. Subsequently, the patient’s Glasgow Coma Scale (GCS) dropped rapidly (from 13/15–8/15) and a new brain CT scan revealed an increase in the intracerebral and intraventricular hemorrhage volume. Immediate surgery was performed, which consisted of decompressive craniectomy, ICH evacuation and placement of an external ventricular drain (EVD). The patient’s postoperative course showed significant recovery with upper moderate disability at 6 months follow-up based on the Glasgow Outcome Scale Extended (GOS-E) and scoring 3 out of 6 based on a modified Rankin scale score.

Conclusion

Timely neurosurgical intervention—including decompressive craniectomy, hematoma evacuation, and EVD placement—can significantly improve outcomes in postpartum patients with ICH and IVH, even in cases with rapid neurological decline. Clinicians should act swiftly when postpartum hypertension and neurological symptoms arise, as early diagnosis and intervention are critical to reducing mortality and long-term disability.
产后脑出血(ICH)和脑室内出血(IVH)是罕见但可能危及生命的疾病。它们通常由高血压疾病引起,如先兆子痫。因此,围产期是监测女性患者的关键时期,特别是那些有高血压急诊风险的女性患者。临床表现女性,32岁,无高血压病史,产后7天出现严重头痛和血压升高(197/104 mmHg)。即时脑CT扫描显示存在大脑出血和IVH,累及所有4个脑室。随后,患者的格拉斯哥昏迷评分(GCS)迅速下降(从13/15-8/15),新的脑部CT扫描显示脑内和脑室内出血量增加。立即进行手术,包括减压颅骨切除术,脑出血排出和放置外脑室引流管(EVD)。术后随访6个月,根据格拉斯哥结局量表扩展(GOS-E),患者表现出明显的恢复和中上残疾,根据改进的Rankin量表评分,患者获得了3分(满分6分)。结论及时的神经外科干预,包括颅脑减压、血肿清除和EVD放置,可以显著改善产后脑出血和IVH患者的预后,即使对神经功能迅速下降的患者也是如此。当产后高血压和神经系统症状出现时,临床医生应迅速采取行动,因为早期诊断和干预对降低死亡率和长期残疾至关重要。
{"title":"Postpartum intracerebral and intraventricular hemorrhage – A case report and review of the literature","authors":"Nikita Grace Mathews ,&nbsp;Andrea Cuschieri ,&nbsp;Mazhar Darwazeh ,&nbsp;Adel Al Sisi ,&nbsp;Kavita Krishnan ,&nbsp;Rami Darwazeh","doi":"10.1016/j.sycrs.2025.100142","DOIUrl":"10.1016/j.sycrs.2025.100142","url":null,"abstract":"<div><h3>Background</h3><div>Postpartum intracerebral hemorrhages (ICH) and intraventricular hemorrhages (IVH) are rare but potentially life-threatening conditions. They are often precipitated by hypertensive disorders, such as preeclampsia. Thus, the peripartum period is a critical time for monitoring female patients, particularly those at risk of hypertensive emergencies.</div></div><div><h3>Clinical presentation</h3><div>A 32-year-old female with no previous history of hypertension presented with severe headaches and elevated blood pressure (197/104 mmHg) seven days after delivery. Immediate brain computed tomography (CT) scan revealed the presence of a large ICH and IVH involving all 4 ventricles. Subsequently, the patient’s Glasgow Coma Scale (GCS) dropped rapidly (from 13/15–8/15) and a new brain CT scan revealed an increase in the intracerebral and intraventricular hemorrhage volume. Immediate surgery was performed, which consisted of decompressive craniectomy, ICH evacuation and placement of an external ventricular drain (EVD). The patient’s postoperative course showed significant recovery with upper moderate disability at 6 months follow-up based on the Glasgow Outcome Scale Extended (GOS-E) and scoring 3 out of 6 based on a modified Rankin scale score.</div></div><div><h3>Conclusion</h3><div>Timely neurosurgical intervention—including decompressive craniectomy, hematoma evacuation, and EVD placement—can significantly improve outcomes in postpartum patients with ICH and IVH, even in cases with rapid neurological decline. Clinicians should act swiftly when postpartum hypertension and neurological symptoms arise, as early diagnosis and intervention are critical to reducing mortality and long-term disability.</div></div>","PeriodicalId":101189,"journal":{"name":"Surgery Case Reports","volume":"6 ","pages":"Article 100142"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144685784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fibrosarcomatous dermatofibrosarcoma protuberans of the scalp, extending to the brain – A rare case report 头皮隆突性皮肤纤维肉瘤,延伸至脑部-罕见病例报告
Pub Date : 2025-07-01 Epub Date: 2025-04-22 DOI: 10.1016/j.sycrs.2025.100113
Kavya Varshney , Naveen Kumar , Charanjeet Ahluwalia , Sunil Ranga
This case report highlights a rare instance of fibrosarcomatous dermatofibrosarcoma protuberans of the scalp with extension to the brain. Dermatofibrosarcoma protuberans is a slow-growing, locally aggressive soft tissue tumor. Fibrosarcomatous dermatofibrosarcoma protuberans is a rare and more aggressive variant of dermatofibrosarcoma protuberans. Fibrosarcomatous transformation in dermatofibrosarcoma protuberans is observed in only 5 % of cases. Although the recurrence rate is higher, metastasis and local extension are rarely seen, and intracranial extension is also uncommon. Clinically, fibrosarcomatous dermatofibrosarcoma protuberans is indistinguishable from classical dermatofibrosarcoma protuberans; hence, histopathological examination remains the cornerstone for definitive diagnosis. Histopathological examination reveals that areas of classical dermatofibrosarcoma protuberans show tumor cells arranged in a monotonous storiform pattern with a lack of circumscription, while areas with fibrosarcomatous transformation exhibit spindle cells arranged in a herringbone pattern, which are negative for CD34 on immunohistochemistry.
这个病例报告强调了一个罕见的头皮纤维肉瘤性皮肤纤维肉瘤,并延伸到大脑。隆突性皮肤纤维肉瘤是一种生长缓慢、局部侵袭性的软组织肿瘤。摘要纤维肉瘤性皮肤纤维肉瘤是一种罕见且侵袭性较强的皮肤纤维肉瘤。隆突性皮肤纤维肉瘤的纤维肉瘤转化仅占5 %。虽然复发率较高,但转移和局部扩展很少见,颅内扩展也不常见。临床上,纤维肉瘤性隆突性皮肤纤维肉瘤与典型的隆突性皮肤纤维肉瘤难以区分;因此,组织病理学检查仍然是明确诊断的基石。组织病理学检查显示经典皮肤纤维肉瘤结节区肿瘤细胞呈单调的故事状排列,缺乏边界,而纤维肉瘤转化区梭形细胞呈人字形排列,免疫组织化学CD34阴性。
{"title":"Fibrosarcomatous dermatofibrosarcoma protuberans of the scalp, extending to the brain – A rare case report","authors":"Kavya Varshney ,&nbsp;Naveen Kumar ,&nbsp;Charanjeet Ahluwalia ,&nbsp;Sunil Ranga","doi":"10.1016/j.sycrs.2025.100113","DOIUrl":"10.1016/j.sycrs.2025.100113","url":null,"abstract":"<div><div>This case report highlights a rare instance of fibrosarcomatous dermatofibrosarcoma protuberans of the scalp with extension to the brain. Dermatofibrosarcoma protuberans is a slow-growing, locally aggressive soft tissue tumor. Fibrosarcomatous dermatofibrosarcoma protuberans is a rare and more aggressive variant of dermatofibrosarcoma protuberans. Fibrosarcomatous transformation in dermatofibrosarcoma protuberans is observed in only 5 % of cases. Although the recurrence rate is higher, metastasis and local extension are rarely seen, and intracranial extension is also uncommon. Clinically, fibrosarcomatous dermatofibrosarcoma protuberans is indistinguishable from classical dermatofibrosarcoma protuberans; hence, histopathological examination remains the cornerstone for definitive diagnosis. Histopathological examination reveals that areas of classical dermatofibrosarcoma protuberans show tumor cells arranged in a monotonous storiform pattern with a lack of circumscription, while areas with fibrosarcomatous transformation exhibit spindle cells arranged in a herringbone pattern, which are negative for CD34 on immunohistochemistry.</div></div>","PeriodicalId":101189,"journal":{"name":"Surgery Case Reports","volume":"5 ","pages":"Article 100113"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143868731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare and remarkable: Exploring the enigma of ciliated cysts of the gallbladder 罕见而非凡:探索胆囊纤毛囊肿之谜
Pub Date : 2025-07-01 Epub Date: 2025-04-23 DOI: 10.1016/j.sycrs.2025.100116
Ovidiu Adrian Bitere , Florina Almari , Corina-Elena Minciuna , Mihai Dodot , Iulia Andrei-Bitere , Gabriela Fota , Catalin Vasilescu , Aurel Tonea , Vlad Herlea

Background

Ciliated cysts of the gallbladder are rare congenital anomalies derived from embryonic foregut remnants. These benign lesions, lined by distinctive ciliated columnar epithelium, present diagnostic challenges due to non-specific imaging findings and their extreme rarity.

Case presentation

A 51-year-old woman presented with intermittent right upper quadrant abdominal pain lasting two years. Imaging revealed a cystic lesion measuring initially 11 × 10 mm on the gallbladder's lateral wall. Due to lesion growth observed over follow-up, laparoscopic cholecystectomy was performed. Histopathology confirmed a subserosal, unilocular cyst lined with ciliated columnar epithelium, without communication to the gallbladder lumen.

Discussion

This report represents the sixteenth documented global case and the first Romanian instance of a gallbladder ciliated cyst. The lesion’s rarity and nonspecific clinical and radiological presentations hinder accurate preoperative diagnosis. Histopathological analysis remains essential to distinguish these cysts from bronchogenic cysts and biliary neoplasms. Surgical excision is advisable, especially when symptoms are present or malignancy cannot be confidently excluded.

Conclusions

Despite their rarity, ciliated gallbladder cysts should be included in the differential diagnosis of atypical cystic gallbladder lesions. Laparoscopic cholecystectomy offers a safe, definitive treatment method, providing both diagnostic confirmation and symptom resolution.
背景胆囊纤毛囊肿是一种罕见的先天性异常,起源于胚胎前肠残余物。这些由独特纤毛柱状上皮排列的良性病变,由于非特异性影像学表现和极其罕见,给诊断带来了挑战。病例介绍:51岁女性,以间歇性右上腹腹痛两年为主诉。影像学显示胆囊侧壁有囊性病变,最初尺寸为11 × 10 mm。由于在随访中观察到病变的增长,我们进行了腹腔镜胆囊切除术。组织病理学证实为浆膜下单眼囊肿,衬有纤毛柱状上皮,未与胆囊腔连通。本报告是全球第16例记录在案的胆囊纤毛囊肿病例,也是罗马尼亚第一例。病变的罕见性和非特异性的临床和放射学表现阻碍了准确的术前诊断。组织病理学分析仍然是必要的,以区分这些囊肿与支气管囊肿和胆道肿瘤。手术切除是可取的,特别是当症状出现或恶性肿瘤不能完全排除时。结论纤毛胆囊囊肿虽罕见,但应列入非典型胆囊病变的鉴别诊断。腹腔镜胆囊切除术提供了一种安全,明确的治疗方法,提供诊断确认和症状解决。
{"title":"Rare and remarkable: Exploring the enigma of ciliated cysts of the gallbladder","authors":"Ovidiu Adrian Bitere ,&nbsp;Florina Almari ,&nbsp;Corina-Elena Minciuna ,&nbsp;Mihai Dodot ,&nbsp;Iulia Andrei-Bitere ,&nbsp;Gabriela Fota ,&nbsp;Catalin Vasilescu ,&nbsp;Aurel Tonea ,&nbsp;Vlad Herlea","doi":"10.1016/j.sycrs.2025.100116","DOIUrl":"10.1016/j.sycrs.2025.100116","url":null,"abstract":"<div><h3>Background</h3><div>Ciliated cysts of the gallbladder are rare congenital anomalies derived from embryonic foregut remnants. These benign lesions, lined by distinctive ciliated columnar epithelium, present diagnostic challenges due to non-specific imaging findings and their extreme rarity.</div></div><div><h3>Case presentation</h3><div>A 51-year-old woman presented with intermittent right upper quadrant abdominal pain lasting two years. Imaging revealed a cystic lesion measuring initially 11 × 10 mm on the gallbladder's lateral wall. Due to lesion growth observed over follow-up, laparoscopic cholecystectomy was performed. Histopathology confirmed a subserosal, unilocular cyst lined with ciliated columnar epithelium, without communication to the gallbladder lumen.</div></div><div><h3>Discussion</h3><div>This report represents the sixteenth documented global case and the first Romanian instance of a gallbladder ciliated cyst. The lesion’s rarity and nonspecific clinical and radiological presentations hinder accurate preoperative diagnosis. Histopathological analysis remains essential to distinguish these cysts from bronchogenic cysts and biliary neoplasms. Surgical excision is advisable, especially when symptoms are present or malignancy cannot be confidently excluded.</div></div><div><h3>Conclusions</h3><div>Despite their rarity, ciliated gallbladder cysts should be included in the differential diagnosis of atypical cystic gallbladder lesions. Laparoscopic cholecystectomy offers a safe, definitive treatment method, providing both diagnostic confirmation and symptom resolution.</div></div>","PeriodicalId":101189,"journal":{"name":"Surgery Case Reports","volume":"5 ","pages":"Article 100116"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143868732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multidisciplinary treatment of the edentulous maxillectomy defect after trauma: A case report with a 2.5-year follow-up 创伤后无牙上颌切除缺损的多学科治疗:1例随访2.5年
Pub Date : 2025-07-01 Epub Date: 2025-06-06 DOI: 10.1016/j.sycrs.2025.100129
Shandan He , Huihui Zeng , Haidong Fan, Huajing Li, Yuyan Zheng
This clinical report is aimed at describing a novel multidisciplinary management of a 40-year-old male patient presented with a severelyk strophic edentulous ridge, a unilateral maxillary defect and an oroantral fistula induced by trauma. The patient-specifical planning workflow consisted of tooth extractions, guided bone regeneration, maxillary sinus floor elevation, dental and zygomatic implant placement, soft tissue augmentation, oroantral fistula closure, and rehabilitation. Several dental disciplines were embraced through the therapeutic period. During the 2.5-year follow-up period, the morphological and functional disorders were recovered clinically and radiographically without concurrent complications. Therefore, a suitable and thorough plan for complicated clinical situations should include various medical branches or sub-branches to ensure a predictable achievement with long-term stability.
本临床报告旨在描述一种新的多学科治疗方法,治疗一名40岁男性患者,其表现为严重的营养不良无牙嵴,单侧上颌缺损和创伤引起的口窦瘘。患者具体的计划工作流程包括拔牙,引导骨再生,上颌窦底提升,牙齿和颧种植体放置,软组织增强,口窦瘘关闭和康复。在治疗期间接受了几个牙科学科。在2.5年的随访期间,形态学和功能障碍均得到临床和影像学恢复,无并发并发症。因此,对于复杂的临床情况,一个合适的、周密的计划应该包括各个医疗分支或支行,以确保可预测的、长期稳定的成果。
{"title":"Multidisciplinary treatment of the edentulous maxillectomy defect after trauma: A case report with a 2.5-year follow-up","authors":"Shandan He ,&nbsp;Huihui Zeng ,&nbsp;Haidong Fan,&nbsp;Huajing Li,&nbsp;Yuyan Zheng","doi":"10.1016/j.sycrs.2025.100129","DOIUrl":"10.1016/j.sycrs.2025.100129","url":null,"abstract":"<div><div>This clinical report is aimed at describing a novel multidisciplinary management of a 40-year-old male patient presented with a <span><span>severely</span></span>k strophic edentulous ridge, a unilateral maxillary defect and an oroantral fistula induced by trauma. The patient-specifical planning workflow consisted of tooth extractions, guided bone regeneration, maxillary sinus floor elevation, dental and zygomatic implant placement, soft tissue augmentation, oroantral fistula closure, and rehabilitation. Several dental disciplines were embraced through the therapeutic period. During the 2.5-year follow-up period, the morphological and functional disorders were recovered clinically and radiographically without concurrent complications. Therefore, a suitable and thorough plan for complicated clinical situations should include various medical branches or sub-branches to ensure a predictable achievement with long-term stability.</div></div>","PeriodicalId":101189,"journal":{"name":"Surgery Case Reports","volume":"5 ","pages":"Article 100129"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144264053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Surgery Case Reports
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