Pub Date : 2026-11-01Epub Date: 2025-11-25DOI: 10.1007/s00380-025-02633-4
Shuri Nakao, Masato Ogawa, Sokichi Maniwa
{"title":"Response to the letter regarding \"Does not only preoperative weight loss but also weight gain affect recovery after cardiac surgery?\"","authors":"Shuri Nakao, Masato Ogawa, Sokichi Maniwa","doi":"10.1007/s00380-025-02633-4","DOIUrl":"10.1007/s00380-025-02633-4","url":null,"abstract":"","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":"783"},"PeriodicalIF":1.5,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145603846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-11-01Epub Date: 2026-04-29DOI: 10.1007/s00380-026-02656-5
Emanuele Cecchi, Andrea Grasso Granchietti, Claudia Assenza, Ilaria Fanizzi, Manuel Garofalo, Francesca Maria Di Muro, Veronica Speranza Vitiello, Francesco Losanno, Sabina Caciolli, Chiara Piazzai, Rossella Marcucci
{"title":"Response to Letters on \"Long-term outcome of tailored antithrombotic therapy based on platelet function testing in patients undergoing percutaneous coronary intervention: a 5-year retrospective cohort study\".","authors":"Emanuele Cecchi, Andrea Grasso Granchietti, Claudia Assenza, Ilaria Fanizzi, Manuel Garofalo, Francesca Maria Di Muro, Veronica Speranza Vitiello, Francesco Losanno, Sabina Caciolli, Chiara Piazzai, Rossella Marcucci","doi":"10.1007/s00380-026-02656-5","DOIUrl":"10.1007/s00380-026-02656-5","url":null,"abstract":"","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":"788-790"},"PeriodicalIF":1.5,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147769896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-11-01Epub Date: 2025-11-25DOI: 10.1007/s00380-025-02632-5
Taichi Matsuo, Shunsuke Taito
{"title":"Does not only preoperative weight loss but also weight gain affect recovery after cardiac surgery?","authors":"Taichi Matsuo, Shunsuke Taito","doi":"10.1007/s00380-025-02632-5","DOIUrl":"10.1007/s00380-025-02632-5","url":null,"abstract":"","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":"782"},"PeriodicalIF":1.5,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145603854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-11-01Epub Date: 2026-04-05DOI: 10.1007/s00380-026-02682-3
Haruto Kitano, Satoshi Katano, Tomohiro Nakajima, Ryohei Nagaoka, Kotaro Yamano, Aki Habaguchi, Junji Nakazawa, Tsuyoshi Shibata, Yutaka Iba
Postoperative delirium (POD) is a serious complication after cardiovascular surgery, and preoperative cognitive impairment is a well-established risk factor. However, the specific cognitive domains relevant to POD prediction remain unclear. This study investigated whether preoperative frontal lobe function, assessed by the Frontal Assessment Battery (FAB), predicts POD in patients undergoing cardiovascular surgery and explored the potential mediating role of frontal executive function in the relationship between global cognitive function and POD. We retrospectively studied 105 patients (mean age 69 ± 12 years) undergoing cardiovascular surgery. Preoperative global cognitive and frontal lobe functions were assessed using the Mini-Mental State Examination (MMSE) and the FAB, respectively. POD was diagnosed using the Confusion Assessment Method for the Intensive Care Unit. POD occurred in 16 patients (15.2%). In univariate analysis, both lower FAB (odds ratio [OR], 0.75; 95% confidence interval [CI] 0.60-0.92) and MMSE (OR, 0.78; 95% CI 0.63-0.97) predicted POD with similar effect sizes. After adjusting for age (≥ 65 years) and sex, FAB remained a significant predictor (adjusted OR, 0.79; 95% CI 0.62-0.99), whereas MMSE showed a similar magnitude of association that did not reach statistical significance (adjusted OR, 0.82; 95% CI 0.65-1.02). Exploratory mediation analysis suggested that FAB may partially mediate the MMSE-POD association (indirect effect: p = 0.029; proportion mediated, 55%), although these findings require cautious interpretation given the limited sample size. Both FAB and MMSE predict POD with comparable effect sizes. Frontal executive function may contribute to the cognitive pathway underlying POD risk, and prospective studies with larger samples are needed to validate these findings.
{"title":"Preoperative frontal lobe and global cognitive function as predictors of postoperative delirium after cardiovascular surgery: a predictive and exploratory mediation analysis.","authors":"Haruto Kitano, Satoshi Katano, Tomohiro Nakajima, Ryohei Nagaoka, Kotaro Yamano, Aki Habaguchi, Junji Nakazawa, Tsuyoshi Shibata, Yutaka Iba","doi":"10.1007/s00380-026-02682-3","DOIUrl":"10.1007/s00380-026-02682-3","url":null,"abstract":"<p><p>Postoperative delirium (POD) is a serious complication after cardiovascular surgery, and preoperative cognitive impairment is a well-established risk factor. However, the specific cognitive domains relevant to POD prediction remain unclear. This study investigated whether preoperative frontal lobe function, assessed by the Frontal Assessment Battery (FAB), predicts POD in patients undergoing cardiovascular surgery and explored the potential mediating role of frontal executive function in the relationship between global cognitive function and POD. We retrospectively studied 105 patients (mean age 69 ± 12 years) undergoing cardiovascular surgery. Preoperative global cognitive and frontal lobe functions were assessed using the Mini-Mental State Examination (MMSE) and the FAB, respectively. POD was diagnosed using the Confusion Assessment Method for the Intensive Care Unit. POD occurred in 16 patients (15.2%). In univariate analysis, both lower FAB (odds ratio [OR], 0.75; 95% confidence interval [CI] 0.60-0.92) and MMSE (OR, 0.78; 95% CI 0.63-0.97) predicted POD with similar effect sizes. After adjusting for age (≥ 65 years) and sex, FAB remained a significant predictor (adjusted OR, 0.79; 95% CI 0.62-0.99), whereas MMSE showed a similar magnitude of association that did not reach statistical significance (adjusted OR, 0.82; 95% CI 0.65-1.02). Exploratory mediation analysis suggested that FAB may partially mediate the MMSE-POD association (indirect effect: p = 0.029; proportion mediated, 55%), although these findings require cautious interpretation given the limited sample size. Both FAB and MMSE predict POD with comparable effect sizes. Frontal executive function may contribute to the cognitive pathway underlying POD risk, and prospective studies with larger samples are needed to validate these findings.</p>","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":"769-781"},"PeriodicalIF":1.5,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147622773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-11-01Epub Date: 2026-02-05DOI: 10.1007/s00380-026-02655-6
Kunal Mahajan, Jai Bharat Sharma, Surender Himral, Vivek Rana
{"title":"Critical unaddressed limitations in PFT-guided antithrombotic therapy after PCI: implications for real-world practice and future research.","authors":"Kunal Mahajan, Jai Bharat Sharma, Surender Himral, Vivek Rana","doi":"10.1007/s00380-026-02655-6","DOIUrl":"10.1007/s00380-026-02655-6","url":null,"abstract":"","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":"784-785"},"PeriodicalIF":1.5,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146124649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-11-01Epub Date: 2026-01-21DOI: 10.1007/s00380-026-02657-4
Rehmat Fayaz, Talha Ali
{"title":"Comment on, \"Long-term outcome of tailored antithrombotic therapy based on platelet function testing in patients undergoing percutaneous coronary intervention: a 5-year retrospective cohort study\".","authors":"Rehmat Fayaz, Talha Ali","doi":"10.1007/s00380-026-02657-4","DOIUrl":"10.1007/s00380-026-02657-4","url":null,"abstract":"","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":"786-787"},"PeriodicalIF":1.5,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146018368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-11-01Epub Date: 2026-04-05DOI: 10.1007/s00380-026-02680-5
Nicholas Wettersten, Yu Horiuchi, Lori B Daniels, Shreya Banerjee, Masahiko Asami, Kengo Tanabe
{"title":"Natriuretic peptides are integral in reclassifying heart failure stage and risk.","authors":"Nicholas Wettersten, Yu Horiuchi, Lori B Daniels, Shreya Banerjee, Masahiko Asami, Kengo Tanabe","doi":"10.1007/s00380-026-02680-5","DOIUrl":"10.1007/s00380-026-02680-5","url":null,"abstract":"","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":"749-759"},"PeriodicalIF":1.5,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147622816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-11-01Epub Date: 2026-05-11DOI: 10.1007/s00380-026-02673-4
Naruka Kaneko, Hirokazu Shiraishi, Ritsuko Kurimoto, Tomotsugu Seki, Naohiko Nakanishi, Kan Zen, Takeshi Nakamura, Tetsuhiro Yamano, Tatsuya Kawasaki, Satoaki Matoba
With the increasing use of minimally invasive catheter-based therapies, early identification of severe aortic stenosis (AS) has become essential. The slow upstroke waveform (Tardus) observed in carotid artery wave analysis is a known feature of AS, and quantitative assessments of Tardus can estimate the severity of AS. Prolongation of ejection time (ET) and upstroke time (UT) is a characteristic of Tardus. However, the clinical relevance of ET and UT measured during brachial-ankle pulse wave velocity (baPWV) assessment remained unclear. This study aimed to develop a predictive model for screening severe AS using baPWV-derived parameters. We enrolled 117 patients with mild to severe AS and 76 control subjects without cardiovascular disease. AS severity was classified based on peak aortic valve velocity (peak V) measured by echocardiography. We evaluated correlations between peak V and baPWV parameters, including ET, UT, and pre-ejection time (PEP), and developed a predictive model to identify severe AS. Peak V correlated significantly with ET, PEP, PEP/ET and mean UT (r = 0.52, - 0.28, - 0.44, 0.33; all p < 0.001). A model incorporating age, body mass index, corrected ET, corrected mean UT and mean percentage of mean arterial pressure (%MAP) showed good predictive value (area under the curve = 0.872). BaPWV-derived parameters may serve as useful noninvasive indicators for diagnosing severe AS.
{"title":"Prediction of severe aortic stenosis using peripheral arterial waveforms during brachial-ankle pulse wave velocity testing.","authors":"Naruka Kaneko, Hirokazu Shiraishi, Ritsuko Kurimoto, Tomotsugu Seki, Naohiko Nakanishi, Kan Zen, Takeshi Nakamura, Tetsuhiro Yamano, Tatsuya Kawasaki, Satoaki Matoba","doi":"10.1007/s00380-026-02673-4","DOIUrl":"10.1007/s00380-026-02673-4","url":null,"abstract":"<p><p>With the increasing use of minimally invasive catheter-based therapies, early identification of severe aortic stenosis (AS) has become essential. The slow upstroke waveform (Tardus) observed in carotid artery wave analysis is a known feature of AS, and quantitative assessments of Tardus can estimate the severity of AS. Prolongation of ejection time (ET) and upstroke time (UT) is a characteristic of Tardus. However, the clinical relevance of ET and UT measured during brachial-ankle pulse wave velocity (baPWV) assessment remained unclear. This study aimed to develop a predictive model for screening severe AS using baPWV-derived parameters. We enrolled 117 patients with mild to severe AS and 76 control subjects without cardiovascular disease. AS severity was classified based on peak aortic valve velocity (peak V) measured by echocardiography. We evaluated correlations between peak V and baPWV parameters, including ET, UT, and pre-ejection time (PEP), and developed a predictive model to identify severe AS. Peak V correlated significantly with ET, PEP, PEP/ET and mean UT (r = 0.52, - 0.28, - 0.44, 0.33; all p < 0.001). A model incorporating age, body mass index, corrected ET, corrected mean UT and mean percentage of mean arterial pressure (%MAP) showed good predictive value (area under the curve = 0.872). BaPWV-derived parameters may serve as useful noninvasive indicators for diagnosing severe AS.</p>","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":"760-768"},"PeriodicalIF":1.5,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147874032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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