Pub Date : 2026-10-28DOI: 10.1177/00220345261489567
D. Dasi,I.J. de Souza Araujo,Y. Zhang,V. Vikram,W. Zhang,J. Liu,L.L. Munn,G.T.-J. Huang
{"title":"Tube and Tooth Fragment Skinfold Models for Pulp Neovascularization Studies: A Qualitative Assessment","authors":"D. Dasi,I.J. de Souza Araujo,Y. Zhang,V. Vikram,W. Zhang,J. Liu,L.L. Munn,G.T.-J. Huang","doi":"10.1177/00220345261489567","DOIUrl":"https://doi.org/10.1177/00220345261489567","url":null,"abstract":"","PeriodicalId":15596,"journal":{"name":"Journal of Dental Research","volume":"84 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149266377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-10-24DOI: 10.1177/00220345261489221
J. Shen, Y. Pan, H. Pikhart, A. Heilmann, G. Tsakos
Healthy aging is a global public health priority, and good oral health is essential for this. While studies in the United Kingdom documented social gradients in oral health measures among adults, they were mostly cross-sectional and conducted before major policy and economic changes. One study examined trends over time in inequalities in tooth loss but used only 1 socioeconomic position (SEP) measure and did not focus on older adults. Our study aimed to examine trends in oral health inequalities by a comprehensive range of SEP indicators among older adults in England from 2006–2007 to 2018–2019. Secondary data analyses used both baseline and refreshment samples from waves 3, 5, 7, and 9 of the English Longitudinal Study of Ageing (ELSA). Oral health outcomes were edentulousness (waves 3–7; 8-y follow-up), self-rated oral health (SROH), and Oral Impacts on Daily Performances (OIDP) (waves 3–9 for both; 12-y follow-up). SEP indicators consisted of education, occupation, household income, and household wealth. Logistic regression with robust standard errors accounting for clustering was used to measure socioeconomic inequalities in oral health over time, controlling for age, sex, and marital status. Odds ratios and predicted probabilities were compared to assess changes in relative and absolute oral health inequalities over 12 y. The prevalence of edentulousness decreased from waves 3 to 7 (data not available for wave 9), while the prevalence of reporting at least 1 oral impact and fair/poor SROH increased from waves 3 to 9. Social gradients were evident across oral health outcomes and for different SEP markers. For all 3 outcomes, relative inequalities remained largely unchanged over the study period. Absolute inequalities slightly narrowed for edentulousness but increased for both SROH and oral impacts. Overall, oral health inequalities among older adults in England have persisted and, in some aspects, widened over these 12 y, highlighting the need for upstream public health strategies to reduce inequalities.
{"title":"Trends in Oral Health Inequalities among Older Adults in England","authors":"J. Shen, Y. Pan, H. Pikhart, A. Heilmann, G. Tsakos","doi":"10.1177/00220345261489221","DOIUrl":"https://doi.org/10.1177/00220345261489221","url":null,"abstract":"Healthy aging is a global public health priority, and good oral health is essential for this. While studies in the United Kingdom documented social gradients in oral health measures among adults, they were mostly cross-sectional and conducted before major policy and economic changes. One study examined trends over time in inequalities in tooth loss but used only 1 socioeconomic position (SEP) measure and did not focus on older adults. Our study aimed to examine trends in oral health inequalities by a comprehensive range of SEP indicators among older adults in England from 2006–2007 to 2018–2019. Secondary data analyses used both baseline and refreshment samples from waves 3, 5, 7, and 9 of the English Longitudinal Study of Ageing (ELSA). Oral health outcomes were edentulousness (waves 3–7; 8-y follow-up), self-rated oral health (SROH), and Oral Impacts on Daily Performances (OIDP) (waves 3–9 for both; 12-y follow-up). SEP indicators consisted of education, occupation, household income, and household wealth. Logistic regression with robust standard errors accounting for clustering was used to measure socioeconomic inequalities in oral health over time, controlling for age, sex, and marital status. Odds ratios and predicted probabilities were compared to assess changes in relative and absolute oral health inequalities over 12 y. The prevalence of edentulousness decreased from waves 3 to 7 (data not available for wave 9), while the prevalence of reporting at least 1 oral impact and fair/poor SROH increased from waves 3 to 9. Social gradients were evident across oral health outcomes and for different SEP markers. For all 3 outcomes, relative inequalities remained largely unchanged over the study period. Absolute inequalities slightly narrowed for edentulousness but increased for both SROH and oral impacts. Overall, oral health inequalities among older adults in England have persisted and, in some aspects, widened over these 12 y, highlighting the need for upstream public health strategies to reduce inequalities.","PeriodicalId":15596,"journal":{"name":"Journal of Dental Research","volume":"3 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149235684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-10-24DOI: 10.1177/00220345261490933
E. Cots, N. Güil-Oumrait, S. Marquez, J.M. Urquiza, C.M. Sol, F. Guinot, P. Toran, V.W.V. Jaddoe, L. Trasande, E.B. Wolvius, L. Kragt
Hypomineralized second primary molars (HSPM) affect approximately 6.8% of children. Molars affected by HSPM mineralize between 20 wk of gestation and 15 to 17 mo of age. Experimental studies suggest that exposure to endocrine-disrupting chemicals, including di-2-ethylhexyl phthalate (DEHP) and bisphenol A (BPA), may disrupt enamel formation, but evidence in humans remains limited. This study investigates the association between prenatal exposure to individual phthalates, BPA, and their mixtures and the odds of HSPM in children. It was embedded in the Generation R study, a population-based prospective birth cohort in the Netherlands. Maternal urinary concentrations of BPA and 11 phthalate metabolites were measured each trimester. HSPM was diagnosed at age 6 y based on European Academy of Paediatric Dentistry criteria. Multivariate logistic regression models and Bayesian weighted quantile sum regression were used to assess individual and mixture associations, respectively. Among 1,160 mother–child pairs, 10.2% of children were diagnosed with HSPM. In single-exposure models, higher prenatal concentrations of monobenzyl phthalate (mBzBP) were associated with lower odds of HSPM (odds ratio [OR] = 0.76; 95% confidence interval [CI]: 0.59 to 0.97). Second-trimester exposure to DEHP metabolites showed a nonsignificant trend toward increased HSPM odds (eg, mEOHP OR = 1.15; 95% confidence interval [CI]: 0.91 to 1.45). Sex-specific associations were observed: higher BPA and phthalate concentrations were associated with lower likelihood of HSPM in girls (eg, BPA OR = 0.70; 95% CI: 0.50 to 0.98) and higher odds in boys ( p -interaction < 0.10). Mixture analyses showed a nonsignificant inverse association for overall prenatal exposure (OR = 0.84; 95% CI: 0.63 to 1.15), with mBzBP contributing most to the mixture. No overall association was observed for DEHP mixture, although sex-specific trends were consistent with single-exposure results. Prenatal exposure to phthalates and BPA may influence HSPM development. These findings highlight the need to consider early-life endocrine-disrupting chemical mixture exposure in HSPM etiology.
{"title":"Prenatal Exposure to Phthalates and Bisphenols in Association with Hypomineralization of Second Primary Molar","authors":"E. Cots, N. Güil-Oumrait, S. Marquez, J.M. Urquiza, C.M. Sol, F. Guinot, P. Toran, V.W.V. Jaddoe, L. Trasande, E.B. Wolvius, L. Kragt","doi":"10.1177/00220345261490933","DOIUrl":"https://doi.org/10.1177/00220345261490933","url":null,"abstract":"Hypomineralized second primary molars (HSPM) affect approximately 6.8% of children. Molars affected by HSPM mineralize between 20 wk of gestation and 15 to 17 mo of age. Experimental studies suggest that exposure to endocrine-disrupting chemicals, including di-2-ethylhexyl phthalate (DEHP) and bisphenol A (BPA), may disrupt enamel formation, but evidence in humans remains limited. This study investigates the association between prenatal exposure to individual phthalates, BPA, and their mixtures and the odds of HSPM in children. It was embedded in the Generation R study, a population-based prospective birth cohort in the Netherlands. Maternal urinary concentrations of BPA and 11 phthalate metabolites were measured each trimester. HSPM was diagnosed at age 6 y based on European Academy of Paediatric Dentistry criteria. Multivariate logistic regression models and Bayesian weighted quantile sum regression were used to assess individual and mixture associations, respectively. Among 1,160 mother–child pairs, 10.2% of children were diagnosed with HSPM. In single-exposure models, higher prenatal concentrations of monobenzyl phthalate (mBzBP) were associated with lower odds of HSPM (odds ratio [OR] = 0.76; 95% confidence interval [CI]: 0.59 to 0.97). Second-trimester exposure to DEHP metabolites showed a nonsignificant trend toward increased HSPM odds (eg, mEOHP OR = 1.15; 95% confidence interval [CI]: 0.91 to 1.45). Sex-specific associations were observed: higher BPA and phthalate concentrations were associated with lower likelihood of HSPM in girls (eg, BPA OR = 0.70; 95% CI: 0.50 to 0.98) and higher odds in boys ( <jats:italic toggle=\"yes\">p</jats:italic> -interaction < 0.10). Mixture analyses showed a nonsignificant inverse association for overall prenatal exposure (OR = 0.84; 95% CI: 0.63 to 1.15), with mBzBP contributing most to the mixture. No overall association was observed for DEHP mixture, although sex-specific trends were consistent with single-exposure results. Prenatal exposure to phthalates and BPA may influence HSPM development. These findings highlight the need to consider early-life endocrine-disrupting chemical mixture exposure in HSPM etiology.","PeriodicalId":15596,"journal":{"name":"Journal of Dental Research","volume":"23 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149235682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-10-24DOI: 10.1177/00220345261489242
J.E. Gallagher, C. Guarnizo-Herreño, D. Kavanagh, Y. Makino, M. Mathur, P. Mossey, B. Varenne, B. O’Connell
{"title":"Response to Letter to the Editor, “Global oral health: defining the research agenda in the public interest.”","authors":"J.E. Gallagher, C. Guarnizo-Herreño, D. Kavanagh, Y. Makino, M. Mathur, P. Mossey, B. Varenne, B. O’Connell","doi":"10.1177/00220345261489242","DOIUrl":"https://doi.org/10.1177/00220345261489242","url":null,"abstract":"","PeriodicalId":15596,"journal":{"name":"Journal of Dental Research","volume":"2 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149235683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-10-24DOI: 10.1177/00220345261493895
J. Wang, Y. Yang, L. Meng, L. Gao, J. Wang, H. Ma, R. Liu, S. Duan, W. Jiang, Q. Gu, H. Lu, W. Zhang
Tooth extraction is commonly followed by alveolar ridge resorption, and conventional barrier membranes act largely as passive barriers that do not actively promote early bony sealing of the socket crest. This study asked whether a barrier membrane redesigned to spatially organize early reparative cells at the socket crest preserves alveolar ridge dimensions. Gelatin methacryloyl (GelMA) membranes bearing V-shaped microgrooves were reinforced with electrospun polycaprolactone (PCL) fibers, and recombinant human bone morphogenetic protein 2 (rhBMP-2) was immobilized by stepwise photocrosslinking. Using primary macrophages and bone marrow–derived mesenchymal stem cells, as well as mouse, rat, and beagle models, we assessed macrophage localization and polarization, hypoxia signaling, lactate metabolism, histone lactylation, bone regeneration, and ridge preservation by micro–computed tomography, histology, immunofluorescence, Western blotting, and quantitative reverse transcription polymerase chain reaction. Early bone regeneration in rat calvarial defects was the primary efficacy outcome, and ridge preservation in beagles was a translational outcome. In exploratory analysis, microgrooves guided early myeloid cell enrichment across the defect and were associated with a localized hypoxic microenvironment, lactate dehydrogenase A–dependent lactate production, histone H3K18 lactylation, and a reparative macrophage phenotype that was reversed by lactate dehydrogenase A inhibition in vitro. At 7 and 14 d, microgrooved membranes showed earlier progression of defect healing and extended new bone toward the defect center. Immobilized rhBMP-2 enhanced regeneration to achieve near-complete calvarial closure within 2 wk. In beagles, central socket healing was more advanced at 2 wk in the sites treated with rhBMP-2 microgrooved membranes . At 3 mo, treated sites retained alveolar ridge width, height, and the buccal bone plate relative to natural healing. Microgrooved barrier membranes combined with localized osteoinduction increased early bone regeneration in a controlled rodent comparison and provide proof of concept for alveolar ridge preservation in a canine extraction model.
{"title":"Osteoinductive Microgrooved Membranes for Alveolar Ridge Preservation","authors":"J. Wang, Y. Yang, L. Meng, L. Gao, J. Wang, H. Ma, R. Liu, S. Duan, W. Jiang, Q. Gu, H. Lu, W. Zhang","doi":"10.1177/00220345261493895","DOIUrl":"https://doi.org/10.1177/00220345261493895","url":null,"abstract":"Tooth extraction is commonly followed by alveolar ridge resorption, and conventional barrier membranes act largely as passive barriers that do not actively promote early bony sealing of the socket crest. This study asked whether a barrier membrane redesigned to spatially organize early reparative cells at the socket crest preserves alveolar ridge dimensions. Gelatin methacryloyl (GelMA) membranes bearing V-shaped microgrooves were reinforced with electrospun polycaprolactone (PCL) fibers, and recombinant human bone morphogenetic protein 2 (rhBMP-2) was immobilized by stepwise photocrosslinking. Using primary macrophages and bone marrow–derived mesenchymal stem cells, as well as mouse, rat, and beagle models, we assessed macrophage localization and polarization, hypoxia signaling, lactate metabolism, histone lactylation, bone regeneration, and ridge preservation by micro–computed tomography, histology, immunofluorescence, Western blotting, and quantitative reverse transcription polymerase chain reaction. Early bone regeneration in rat calvarial defects was the primary efficacy outcome, and ridge preservation in beagles was a translational outcome. In exploratory analysis, microgrooves guided early myeloid cell enrichment across the defect and were associated with a localized hypoxic microenvironment, lactate dehydrogenase A–dependent lactate production, histone H3K18 lactylation, and a reparative macrophage phenotype that was reversed by lactate dehydrogenase A inhibition in vitro. At 7 and 14 d, microgrooved membranes showed earlier progression of defect healing and extended new bone toward the defect center. Immobilized rhBMP-2 enhanced regeneration to achieve near-complete calvarial closure within 2 wk. In beagles, central socket healing was more advanced at 2 wk in the sites treated with rhBMP-2 microgrooved membranes . At 3 mo, treated sites retained alveolar ridge width, height, and the buccal bone plate relative to natural healing. Microgrooved barrier membranes combined with localized osteoinduction increased early bone regeneration in a controlled rodent comparison and provide proof of concept for alveolar ridge preservation in a canine extraction model.","PeriodicalId":15596,"journal":{"name":"Journal of Dental Research","volume":"117 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149235681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-10-23DOI: 10.1177/00220345261489217
C.R. Ferrari, E.A. Taira, V.T. Pelá, T.F. Carlos, E.P. de Souza, T.M.O. Ventura, A. Lussi, F. Henrique-Silva, M.A.R. Buzalaf
This study investigated the interaction of CaneStat, a recombinant hybrid protein, with hydroxyapatite using quartz crystal microbalance with dissipation monitoring (QCM-D), and evaluated its effect on early enamel erosion in vivo. For QCM-D analysis, hydroxyapatite-coated sensors were treated with CaneStat (0.01, 0.025, 0.05, 0.1, and 0.5 mg/mL), followed by saliva exposure to allow acquired pellicle formation. Frequency (Δf) and dissipation (ΔD) shifts were analyzed to estimate film mass, thickness, viscosity, and elasticity. In vivo, a randomized, triple-blind, crossover study was conducted with 18 healthy volunteers. After prophylaxis, participants rinsed with deionized water (negative control), Elmex Erosion Protection (positive control), or CaneStat (0.025 mg/mL). The pellicle was allowed to form for 3 min or 2 h prior to an erosive challenge. The percentage of surface reflection intensity (%SRI) was measured. Data normality was assessed using the Shapiro–Wilk test, and a 2-way repeated-measures analysis of variance/Šidák’s multiple comparisons test was applied ( P < 0.05). QCM-D results showed that the 0.025-mg/mL concentration produced a film with reduced thickness and mass but higher viscosity and elasticity than other concentrations. Frequency shifts confirmed stable adsorption after saliva exposure and rinsing, while dissipation changes suggested the formation of a viscoelastic layer. In vivo, %SRI was influenced by both treatment and pellicle formation time. At 3 min and 2 h, Elmex (94.2% ± 21.3% and 99.4% ± 21.1%, respectively) and CaneStat (96.6% ± 19.6% and 115.7% ± 33.7%, respectively) showed higher values than deionized water (60.1% ± 11.7% and 77.5% ± 16.8%, respectively), indicating protection against initial erosion compared with the negative control. CaneStat promoted the formation of a pellicle with distinct physicochemical properties and was associated with increased resistance to an early erosive challenge in vivo, highlighting the potential of recombinant hybrid proteins as a novel strategy for dental erosion prevention.
{"title":"CaneStat Modulates Pellicle Properties and Reduces Enamel Erosion In Vivo","authors":"C.R. Ferrari, E.A. Taira, V.T. Pelá, T.F. Carlos, E.P. de Souza, T.M.O. Ventura, A. Lussi, F. Henrique-Silva, M.A.R. Buzalaf","doi":"10.1177/00220345261489217","DOIUrl":"https://doi.org/10.1177/00220345261489217","url":null,"abstract":"This study investigated the interaction of CaneStat, a recombinant hybrid protein, with hydroxyapatite using quartz crystal microbalance with dissipation monitoring (QCM-D), and evaluated its effect on early enamel erosion in vivo. For QCM-D analysis, hydroxyapatite-coated sensors were treated with CaneStat (0.01, 0.025, 0.05, 0.1, and 0.5 mg/mL), followed by saliva exposure to allow acquired pellicle formation. Frequency (Δf) and dissipation (ΔD) shifts were analyzed to estimate film mass, thickness, viscosity, and elasticity. In vivo, a randomized, triple-blind, crossover study was conducted with 18 healthy volunteers. After prophylaxis, participants rinsed with deionized water (negative control), Elmex Erosion Protection (positive control), or CaneStat (0.025 mg/mL). The pellicle was allowed to form for 3 min or 2 h prior to an erosive challenge. The percentage of surface reflection intensity (%SRI) was measured. Data normality was assessed using the Shapiro–Wilk test, and a 2-way repeated-measures analysis of variance/Šidák’s multiple comparisons test was applied ( <jats:italic toggle=\"yes\">P</jats:italic> < 0.05). QCM-D results showed that the 0.025-mg/mL concentration produced a film with reduced thickness and mass but higher viscosity and elasticity than other concentrations. Frequency shifts confirmed stable adsorption after saliva exposure and rinsing, while dissipation changes suggested the formation of a viscoelastic layer. In vivo, %SRI was influenced by both treatment and pellicle formation time. At 3 min and 2 h, Elmex (94.2% ± 21.3% and 99.4% ± 21.1%, respectively) and CaneStat (96.6% ± 19.6% and 115.7% ± 33.7%, respectively) showed higher values than deionized water (60.1% ± 11.7% and 77.5% ± 16.8%, respectively), indicating protection against initial erosion compared with the negative control. CaneStat promoted the formation of a pellicle with distinct physicochemical properties and was associated with increased resistance to an early erosive challenge in vivo, highlighting the potential of recombinant hybrid proteins as a novel strategy for dental erosion prevention.","PeriodicalId":15596,"journal":{"name":"Journal of Dental Research","volume":"25 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149232196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Children and adolescents often spend substantial time engaged in screen-based activities for both educational and recreational purposes. Excessive screen time has been associated with adverse health outcomes, potentially mediated by shared unhealthy behaviors such as poor dietary habits and inadequate toothbrushing. The aim of this study was to examine the direct and indirect pathways linking screen time to adolescents’ oral clinical conditions and oral health–related quality of life (OHRQoL), considering contextual, family, and individual factors within a comprehensive theoretical framework. An observational longitudinal study was conducted in Manaus, Brazil, from 2024 to 2025, including 610 twelve-year-old adolescents enrolled in urban public schools. The theoretical model, adapted from Fisher-Owens et al (2007), incorporated community, family, and individual-level variables. Data were collected through self-administered questionnaires completed by participants and their parents/guardians, alongside clinical oral examinations conducted in private settings within schools. Structural equation modeling (SEM) was used to estimate direct and indirect effects. A hierarchical structure of associations across contextual, socioeconomic, relational, and individual levels influencing oral health outcomes was observed. Screen time was not directly associated with oral clinical conditions but was linked to a higher impact on OHRQoL (β = 0.202, P = 0.002) and lower toothbrushing frequency (β = −0.139, P = 0.031). A higher impact on OHRQoL was also related to higher sugar consumption (β = 0.142, P = 0.004) and poorer clinical oral condition (β = 0.174, P = 0.005). Socioeconomic status played a major role, contributing to multiple direct and indirect pathways linking contextual and relational factors to the outcomes. In conclusion, screen-related behaviors are embedded within broader familial and social contexts, with socioeconomic conditions influencing multiple pathways to adolescents’ oral health outcomes. Interventions targeting family environments, parental practices, and behavioral habits, alongside strategies addressing socioeconomic disparities, may reduce behavioral risks and improve adolescent oral health.
儿童和青少年经常花费大量时间从事基于屏幕的活动，以达到教育和娱乐的目的。过多的屏幕时间与不利的健康结果有关，可能是由不良饮食习惯和刷牙不足等共同的不健康行为介导的。本研究的目的是在一个全面的理论框架内，考虑环境、家庭和个人因素，研究屏幕时间与青少年口腔临床状况和口腔健康相关生活质量（OHRQoL）之间的直接和间接联系。从2024年到2025年，在巴西的玛瑙斯进行了一项观察性纵向研究，其中包括610名在城市公立学校就读的12岁青少年。该理论模型改编自Fisher-Owens等人（2007），纳入了社区、家庭和个人层面的变量。数据通过参与者及其父母/监护人自行填写的问卷收集，并在学校内的私人场所进行临床口腔检查。结构方程模型（SEM）用于估计直接和间接影响。在影响口腔健康结果的背景、社会经济、关系和个人水平上观察到关联的层次结构。屏幕时间与口腔临床状况无直接关系，但与OHRQoL （β = 0.202, P = 0.002）和较低的刷牙频率（β = - 0.139, P = 0.031）相关。较高的糖摄入量（β = 0.142, P = 0.004）和较差的临床口腔状况（β = 0.174, P = 0.005）对OHRQoL的影响也较高。社会经济地位发挥了主要作用，促成了将情境和相关因素与结果联系起来的多种直接和间接途径。总之，与屏幕相关的行为嵌入在更广泛的家庭和社会背景中，社会经济条件影响青少年口腔健康结果的多种途径。针对家庭环境、父母做法和行为习惯的干预措施，以及解决社会经济差异的策略，可能会降低行为风险，改善青少年口腔健康。
{"title":"Contextual, Family, and Individual Pathways from Screen Time to Oral Health","authors":"I.N. Rego, S.R. Baker, M.A.B. Rebelo, M.V. Vettore, J.M. Rebelo Vieira","doi":"10.1177/00220345261488353","DOIUrl":"https://doi.org/10.1177/00220345261488353","url":null,"abstract":"Children and adolescents often spend substantial time engaged in screen-based activities for both educational and recreational purposes. Excessive screen time has been associated with adverse health outcomes, potentially mediated by shared unhealthy behaviors such as poor dietary habits and inadequate toothbrushing. The aim of this study was to examine the direct and indirect pathways linking screen time to adolescents’ oral clinical conditions and oral health–related quality of life (OHRQoL), considering contextual, family, and individual factors within a comprehensive theoretical framework. An observational longitudinal study was conducted in Manaus, Brazil, from 2024 to 2025, including 610 twelve-year-old adolescents enrolled in urban public schools. The theoretical model, adapted from Fisher-Owens et al (2007), incorporated community, family, and individual-level variables. Data were collected through self-administered questionnaires completed by participants and their parents/guardians, alongside clinical oral examinations conducted in private settings within schools. Structural equation modeling (SEM) was used to estimate direct and indirect effects. A hierarchical structure of associations across contextual, socioeconomic, relational, and individual levels influencing oral health outcomes was observed. Screen time was not directly associated with oral clinical conditions but was linked to a higher impact on OHRQoL (β = 0.202, <jats:italic toggle=\"yes\">P</jats:italic> = 0.002) and lower toothbrushing frequency (β = −0.139, <jats:italic toggle=\"yes\">P</jats:italic> = 0.031). A higher impact on OHRQoL was also related to higher sugar consumption (β = 0.142, <jats:italic toggle=\"yes\">P</jats:italic> = 0.004) and poorer clinical oral condition (β = 0.174, <jats:italic toggle=\"yes\">P</jats:italic> = 0.005). Socioeconomic status played a major role, contributing to multiple direct and indirect pathways linking contextual and relational factors to the outcomes. In conclusion, screen-related behaviors are embedded within broader familial and social contexts, with socioeconomic conditions influencing multiple pathways to adolescents’ oral health outcomes. Interventions targeting family environments, parental practices, and behavioral habits, alongside strategies addressing socioeconomic disparities, may reduce behavioral risks and improve adolescent oral health.","PeriodicalId":15596,"journal":{"name":"Journal of Dental Research","volume":"10 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149232197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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