Journal of geriatric oncology最新文献

{"title":"Evaluation protocol for older adults with hematologic malignancies in a Latin American Cancer Center","authors":"S. Borquez , R. Quilodrán , G. Godoy , C. Cabrera , G. Gajardo","doi":"10.1016/j.jgo.2026.102878","DOIUrl":"10.1016/j.jgo.2026.102878","url":null,"abstract":"","PeriodicalId":15943,"journal":{"name":"Journal of geriatric oncology","volume":"17 2","pages":"Article 102878"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147448723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inclusion of older adult-specific policies in national cancer control plans (NCCPs) and non-communicable disease plans (NCDPs)","authors":"D. Dulak , D. Trapani , Y. Romero , E. Soto Pérez de Celis","doi":"10.1016/j.jgo.2026.102871","DOIUrl":"10.1016/j.jgo.2026.102871","url":null,"abstract":"","PeriodicalId":15943,"journal":{"name":"Journal of geriatric oncology","volume":"17 2","pages":"Article 102871"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147448958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Senior adult oncology program at Moffitt Cancer Center- An innovative multidisciplinary care approach","authors":"M. Extermann","doi":"10.1016/j.jgo.2026.102903","DOIUrl":"10.1016/j.jgo.2026.102903","url":null,"abstract":"<div><div>The Senior Adult Oncology Program at Moffitt is a pioneering Geriatric Oncology Care Model that focuses on a multi-disciplinary team approach to optimizing care of older adults. The team is comprised of dedicated medical oncologists, nurse practioners, medical assistants, nursing team, dietician, social work, and pharmacy who assess and treat the patient with a comprehensive approach, not only focusing on the cancer, but also addressing any physical, nutritional, and psychosocial issues that could impact their care.</div><div>Our approach starts with a nurse initiating a phone call to the patient within 72 hours of appointment scheduling. During this call, the SAOP3 Questionnaire is performed to identify any needs prior to the visit. If there is a negative screen, the patient proceeds with usual care and management with the oncologist. If there is a positive screen along a geriatric domain, this initiates further workup, and appointments are scheduled with the social work, dietician, and pharmacist for the day of the appointment. This allows patients to have a planned comprehensive evaluation on the day of the visit, without the burden of multiple followup appointments.</div><div>On the day of the visit, the medical assistant guides the patient to perform the Timed Up and Go test after completing the vitals, and the clinic nurse completes a mini-COG with the patient during the nursing evaluation. These evaluations are given to the oncologist prior to the oncologist’s visit with the patient. Once they have been completely evaluated, a treatment plan is made, taking into account all the other assessments that have been performed by the team. This plan is then discussed at a weekly tumor board, which is attended by all members of the program to get final input on the plan of care.</div><div>Throughout the patient’s care at Moffitt, the SAOP3, TUG, and mini-COG may be repeated at varying intervals, such as changes in treatment, after hospitalizations, or after falls. This is an ongoing area of research within our team to identify optimal time points for repetition of these assessments.</div></div>","PeriodicalId":15943,"journal":{"name":"Journal of geriatric oncology","volume":"17 2","pages":"Article 102903"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147449068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiotoxicity in older patients with HER2-positive early breast cancer undergoing neoadjuvant dual HER2 blockade and chemotherapy: A real-world cohort study","authors":"I. Furtado,&nbsp;R. Ferreira,&nbsp;R. Escaleira,&nbsp;F. Verdasca,&nbsp;M. Seladas,&nbsp;A. Montenegro,&nbsp;D. Simão,&nbsp;L. Fernandes,&nbsp;S. Oliveira","doi":"10.1016/j.jgo.2026.102868","DOIUrl":"10.1016/j.jgo.2026.102868","url":null,"abstract":"","PeriodicalId":15943,"journal":{"name":"Journal of geriatric oncology","volume":"17 2","pages":"Article 102868"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147449071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BDNF genotype and cognition in older adults with breast cancer and healthy controls in the Thinking and Living with Cancer Study","authors":"Zev M. Nakamura ,&nbsp;Brent J. Small ,&nbsp;Xingtao Zhou ,&nbsp;Jaeil Ahn ,&nbsp;Tim A. Ahles ,&nbsp;Ashley L. Artese ,&nbsp;Harvey Jay Cohen ,&nbsp;Martine Extermann ,&nbsp;Deena Graham ,&nbsp;Claudine Isaacs ,&nbsp;Heather S.L. Jim ,&nbsp;Brenna C. McDonald ,&nbsp;Kelly Nudelman ,&nbsp;Sunita K. Patel ,&nbsp;Kelly E. Rentscher ,&nbsp;James C. Root ,&nbsp;Andrew J. Saykin ,&nbsp;Kathleen Van Dyk ,&nbsp;Claire E. Wegel ,&nbsp;Jeanne S. Mandelblatt ,&nbsp;Judith E. Carroll","doi":"10.1016/j.jgo.2025.102834","DOIUrl":"10.1016/j.jgo.2025.102834","url":null,"abstract":"","PeriodicalId":15943,"journal":{"name":"Journal of geriatric oncology","volume":"17 2","pages":"Article 102834"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145735297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring decisional control preferences in older patients with cancer and their caregivers","authors":"Sofiia Hryniv ,&nbsp;Elizabeth Gilbride ,&nbsp;William Consagra ,&nbsp;Supriya Mohile ,&nbsp;Sule Yilmaz ,&nbsp;Kaitlin Kyi ,&nbsp;Sindhuja Kadambi ,&nbsp;Marielle Jensen-Battaglia ,&nbsp;Nikesha Gilmore ,&nbsp;Mary Whitehead ,&nbsp;Jamil Khatri ,&nbsp;Fadi S. Braiteh ,&nbsp;Alison Conlin ,&nbsp;Kah Poh Loh ,&nbsp;Allison Magnuson","doi":"10.1016/j.jgo.2025.102832","DOIUrl":"10.1016/j.jgo.2025.102832","url":null,"abstract":"<div><h3>Introduction</h3><div>Exploring informational and decisional control preferences as well as examining concordance and patient-caregiver-physician factors associated with preferences in older adults with cancer and their caregivers may help to better understand the role of caregivers in supporting decision-making.</div></div><div><h3>Materials and methods</h3><div>We utilized data from a national geriatric assessment (GA) cluster-randomized trial (NCT 02054741; PI: Mohile) that recruited patients aged ≥70 with incurable cancer, their caregivers, and oncologists. Dyadic decision-making control preferences were measured by the Control Preferences Scale (CPS). Patients and caregivers were asked to describe patient's role in treatment decision-making (patient-role CPS); patients and caregivers were also asked to describe the caregiver's role in treatment decision-making (caregiver-role CPS). Matching patient-caregiver responses were considered concordant. Patients and caregivers were also asked about their information preferences regarding the amount of detail about the patients' illness using a scale from 1 (fewest detail) to 5 (the most detail). We used descriptive statistics to summarize CPS, informational preferences, and concordance in responses. We utilized logistic regression to assess dyads' sociodemographic information, patients' GA domain impairments, and physicians' practice characteristics associated with patient-caregiver CPS concordance.</div></div><div><h3>Results</h3><div>A total of 332 dyads participated; mean age (SD) of patients and caregivers was 76.6 (5.3) and 66.6 (12.2), respectively. Preferences for treatment decision-making varied, with some preferring shared decision-making and others preferring the doctor to make decisions. Concordance between patients and caregivers was observed in 46 % for patient-role CPS and 54 % for caregiver-role CPS. Baseline factors were not associated with dyad concordance. The majority of patients and caregivers preferred the most detailed information about the patient's illness.</div></div><div><h3>Discussion</h3><div>Clinicians should assess patients' and caregivers' informational and decisional control preferences for optimal support in decision-making.</div></div>","PeriodicalId":15943,"journal":{"name":"Journal of geriatric oncology","volume":"17 2","pages":"Article 102832"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145735296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening for frailty and malnutrition in a multidisciplinary head and neck cancer program","authors":"Eden R. Brauer ,&nbsp;Stephanie Lazaro ,&nbsp;Denice R. Economou ,&nbsp;David Rapkin ,&nbsp;Deborah J. Wong ,&nbsp;Maie A. St. John","doi":"10.1016/j.jgo.2026.102892","DOIUrl":"10.1016/j.jgo.2026.102892","url":null,"abstract":"<div><h3>Introduction</h3><div>Frailty and malnutrition are strong predictors of adverse outcomes in patients with head and neck cancer, yet remain underassessed in routine clinical care. This project aimed to develop, implement, and evaluate a standardized screening process for frailty and malnutrition in a multidisciplinary head and neck cancer program to identify high-risk patients and inform treatment planning.</div></div><div><h3>Materials and methods</h3><div>Through a quality improvement initiative, a multidisciplinary team integrated the Risk Analysis Index for Cancer (RAI-C) for frailty and Malnutrition Screening Tool (MST) into routine intake for new referrals of patients with head and neck cancer. Implementation was evaluated across three domains: feasibility, measured through completion rates, acceptability, assessed using clinician feedback via a survey, and impact on patient outcomes, using survival analysis.</div></div><div><h3>Results</h3><div>Among 585 eligible patients, 488 (83.4%) were successfully screened. The cohort (mean age 63.1 years, 64% male) demonstrated high frailty prevalence with 57.2% categorized as frail (RAI-C score ≥ 37) and 14.3% at risk for malnutrition (MST score ≥ 2). In multivariable analysis adjusted for tumor site, treatment intensity, and comorbidities, frail patients had a more than 3-fold increased mortality risk compared to non-frail patients (adjusted HR 3.07, 95% CI 1.50–6.30, <em>p</em> = 0.002). Similarly, malnourished patients showed a 2.8-fold increased mortality risk compared to non-malnourished patients (adjusted HR 2.77, 95% CI 1.52–5.03, <em>p</em> &lt; 0.001). Clinician feedback (<em>n</em> = 14) emphasized the value of screening in promoting “whole person” treatment planning, with suggestions for developing standardized pathways for interventions based on screening results.</div></div><div><h3>Discussion</h3><div>Implementing frailty and malnutrition screening in multidisciplinary head and neck cancer care is feasible, acceptable to clinicians, and identifies patients at significantly higher mortality risk. The strong association between screening results and survival validates these tools' clinical utility and supports their integration into routine practice. Future directions include developing a structured prehabilitation program targeted to modifiable risk factors identified through screening to potentially improve outcomes in this vulnerable population.</div></div>","PeriodicalId":15943,"journal":{"name":"Journal of geriatric oncology","volume":"17 2","pages":"Article 102892"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146213342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tolerability of docetaxel in octogenarians with metastatic prostate cancer in the triplet therapy era: A single-center retrospective cohort study","authors":"Kimitsugu Usui,&nbsp;Atsuto Suzuki,&nbsp;Hayato Kubo,&nbsp;Takahiro Matsumoto,&nbsp;Tomohiko Aigase,&nbsp;Takeshi Kishida,&nbsp;Noboru Nakaigawa","doi":"10.1016/j.jgo.2025.102844","DOIUrl":"10.1016/j.jgo.2025.102844","url":null,"abstract":"","PeriodicalId":15943,"journal":{"name":"Journal of geriatric oncology","volume":"17 2","pages":"Article 102844"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145837494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of hospital volume on mortality in adult women over 65 with triple-negative breast cancer","authors":"Barnabas T. Obeng-Gyasi ,&nbsp;Demond L. Handley ,&nbsp;Mohamed I. Elsaid ,&nbsp;Eric Schupp ,&nbsp;Daniel G. Stover ,&nbsp;J.C. Chen ,&nbsp;Jesus D. Anampa ,&nbsp;Xiaoyi Teng ,&nbsp;Samilia Obeng-Gyasi","doi":"10.1016/j.jgo.2025.102845","DOIUrl":"10.1016/j.jgo.2025.102845","url":null,"abstract":"<div><h3>Introduction</h3><div>Older adults (≥65 years) with triple-negative breast cancer (TNBC) have higher mortality rates than younger patients, due in part to greater comorbidity and lower rates of treatment. However, the impact of hospital volume on survival outcomes in this population remains understudied. This study examined the relationship between hospital volume and survival among older adults (aged 65 years or older) diagnosed with TNBC.</div></div><div><h3>Materials and methods</h3><div>The National Cancer Database was queried for women ages ≥65 years with stage I–III TNBC diagnosed between 2010 and 2020. Annual hospital volume was the facility-level average of breast cancer cases treated in the years before the year of diagnosis. Volumes were divided into quartiles, with the lowest quartile (≤136 cases/year) defined as low-volume and the remaining three quartiles combined as high-volume. Sociodemographic, clinical, and treatment characteristics were compared according to hospital volume status. Crude and adjusted mortality risk differences and relative risks were estimated using pooled logistic regression models.</div></div><div><h3>Results</h3><div>The study cohort comprised 37,538 older women with TNBC, of whom 25 % (<em>n</em> = 9388) were treated at low-volume hospitals. Patients treated at low-volume hospitals were slightly older (73 years [IQR: 68 to 79] vs. 72 years [IQR: 68 to 78 years]) and traveled a shorter distance to the hospitals (6.80 miles [IQR: 3.00 to 14.30] vs 8.60 miles [IQR: 4.30 to 18.00]) than those treated at high-volume hospitals (<em>p</em> &lt; 0.001). On adjusted analysis, treatment at low-volume hospitals (Low-Value Risk: 0.607, 95 % CI: 0.579 to 0.638) was associated with a 5.5 % increased risk of all-cause mortality compared to treatment at high-volume hospitals (High-Volume Risk: 0.576, 95 % CI: 0.556 to 0.592) (RR: 1.055, 95 % CI: 1.003 to 1.121). Patients treated at low-volume hospitals had a 3.2 % excess adjusted risk of mortality compared to those treated at higher-volume hospitals (RD: 3.2 %, 95 % CI: 0.2 % to 6.9 %).</div></div><div><h3>Discussion</h3><div>Older adults treated at low-volume hospitals had modestly higher mortality than those at high-volume facilities. Future work should identify mechanisms underlying this relationship and assess whether referral patterns for older adults should consider hospital volume.</div></div>","PeriodicalId":15943,"journal":{"name":"Journal of geriatric oncology","volume":"17 2","pages":"Article 102845"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145788162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality cancer care for older adults from culturally and linguistically diverse backgrounds: Perspectives from the Cancer and Aging Research Group Junior Board","authors":"Surbhi Singhal ,&nbsp;Maya Abdallah ,&nbsp;Tanyanika Phillips ,&nbsp;Nicole A. Arrato ,&nbsp;Mukul Roy ,&nbsp;Samantha Werts-Pelter ,&nbsp;Katherine Ramos ,&nbsp;Chad Yixian Han","doi":"10.1016/j.jgo.2026.102853","DOIUrl":"10.1016/j.jgo.2026.102853","url":null,"abstract":"","PeriodicalId":15943,"journal":{"name":"Journal of geriatric oncology","volume":"17 2","pages":"Article 102853"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146010374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}