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EFFICACY OF METHOTREXATE VERSUS LEFLUNOMIDE VERSUS COMBINATION OF BOTH IN ACTIVE RHEUMATOID ARTHRITIS 甲氨蝶呤与来氟米特与两者联合治疗活动性类风湿关节炎的疗效
Pub Date : 2021-12-30 DOI: 10.51253/pafmj.v6i6.4646
S. H. Tirmizi, A. Fakhr, Ahsan Amer, Kaswar Sajjad, K. Nawaz, A. Sharif
Objective: To determine the efficacy of Methotrexate versus Leflunomide versus combination of both among patients managed at Pak Emirates Military Hospital with active rheumatoid arthritis. Study Design: Prospective comparative study. Place and Duration of Study: Rheumatology/General Medicine Department, Pak Emirates Military Hospital Rawalpindi, from May 2019 to June 2020. Methodology: Patient of active rheumatoid arthritis who fulfilled American college of rheumatology criteria of 1997 were included in the study. They were randomly divided into three groups with group A receiving Methotrexate, group B receiving Leflunomide while group C received the combination of both Methotrexate and Leflunomide. Disease activity was assessed by using the Disease Activity Score-28 in all the three groups after three months of treatment. Results: Mean age of the study participants was 36.919 ± 6.85 years. One hundred and fifty (83.3%) patients were female while 30 (16.7%) were male. Out of 160 (88.9%) patients achieved remission according to Disease Activity Score-28 score at the end of three months while 20 (11.1%) did not achieve remission. Pearson chi-square test revealed that none of the factors studied including the treatment option had any statistically significant relationship with presence of remission among the target population (p-value 0.386, 0.815, 0.194 and 0.145 for age, gender, duration of symptoms and type of treatment respectively). Conclusion: Remission rate among the rheumatoid arthritis patients in response to treatment was overall good in the study. In terms of efficacy for symptoms of rheumatoid arthritis and achieving remission, after three months of treatment all the three options..................
目的:确定在阿联酋军事医院治疗的活动性类风湿关节炎患者中甲氨蝶呤与来氟米特与两者联合治疗的疗效。研究设计:前瞻性比较研究。学习地点和时间:2019年5月至2020年6月,巴基斯坦拉瓦尔品第阿联酋军事医院风湿病科/综合医学科。方法:研究对象为符合1997年美国风湿病学会标准的活动性类风湿关节炎患者。随机分为A组甲氨蝶呤、B组来氟米特、C组甲氨蝶呤和来氟米特联合用药。治疗三个月后,三组患者的疾病活动度采用疾病活动度评分-28进行评估。结果:研究参与者的平均年龄为36.919±6.85岁。女性150例(83.3%),男性30例(16.7%)。在160例(88.9%)患者中,根据疾病活动评分(Disease Activity score -28)在3个月结束时达到缓解,而20例(11.1%)患者未达到缓解。皮尔逊卡方检验显示,包括治疗方案在内的所有研究因素与目标人群的缓解存在无统计学意义的关系(年龄、性别、症状持续时间和治疗类型的p值分别为0.386、0.815、0.194和0.145)。结论:类风湿关节炎患者对治疗的总体缓解率良好。就类风湿性关节炎症状的疗效和达到缓解而言,治疗三个月后,所有三种选择..................
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引用次数: 1
OCULAR SURFACE DISEASE AMONG PATIENTS WITH OPEN ANGLE GLAUCOMA USING TOPICAL ANTI-GLAUCOMA MEDICATIONS 外用抗青光眼药物治疗开角型青光眼患者的眼表疾病
Pub Date : 2021-12-30 DOI: 10.51253/pafmj.v6i6.4093
Hassaan Javaid, Omar Zafar, Seemal Akram, S. Abbas, Ikram-ullah Khan, H. Javaid
Objective: To determine the frequency of ocular surface disease among patients with open angle glaucoma using topical antiglaucoma medications presenting at a tertiary care eye hospital. Study Design: Cross-sectional analytical study. Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi, from May 2019 to Jan 2020. Methodology: One hundred and eighty patients aged 18 or more, with open angle glaucoma using any of the topical antiglaucoma medications including preparations of dorzolamide, brimonidine, timolol, levobunolol, betaxolol, latanoprost, travoprost, bimatoprost or a combination of these for more than six months took part in the study. Ocular surface disease index was used to assess the presence and severity of ocular surface disease. Results: Out of 180 patients of glaucoma managed with topical anti-glaucoma medications, 83 (46.1%) did not show presence of ocular surface disease when ocular surface disease index was administered. Twenty-nine (16.1%) patients had mild symptoms, 17 (9.4%) had moderate symptoms while 51 (28.3%) patients reported severe symptoms of ocular surface disease. Advancing age and longer duration of treatment with topical anti-glaucoma medications had statistically significant association with the presence of ocular surface disease (p-value <0.05). Conclusion: Presence of ocular surface disease was a common finding among patients using topical agents for the management of glaucoma. Advancing age and prolonged use of anti-glaucoma medication emerged as risk factors statistically related to the presence of ocular surface disease.
目的:了解三级眼科医院外用抗青光眼药物治疗的开角型青光眼患者眼表疾病的发生率。研究设计:横断面分析研究。学习地点和时间:2019年5月至2020年1月,拉瓦尔品第军队眼科研究所。方法:180名18岁或以上的开角型青光眼患者,使用任何外用抗青光眼药物,包括dorzolamide, brimonidine, timolol,左旋布诺洛尔,倍他洛尔,latanoprost,曲伏前列素,bimatoprost或这些药物的组合超过6个月参加了这项研究。眼表疾病指数用于评估眼表疾病的存在和严重程度。结果:在180例接受局部抗青光眼药物治疗的青光眼患者中,83例(46.1%)在给予眼表疾病指数时未显示出眼表疾病的存在。轻度症状29例(16.1%),中度症状17例(9.4%),重度眼表疾病51例(28.3%)。年龄越大、局部抗青光眼药物治疗时间越长与眼表疾病的存在有统计学意义(p值<0.05)。结论:在使用外用药物治疗青光眼的患者中,存在眼表疾病是一个常见的发现。高龄和长期使用抗青光眼药物是与眼表疾病相关的危险因素。
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引用次数: 0
AUDIT OF MANAGEMENT OF ADULT CHOLEDOCHAL CYSTS 成人胆总管囊肿治疗的审计
Pub Date : 2021-12-30 DOI: 10.51253/pafmj.v6i6.4476
A. Nasir, Muhammad Shoaib Khan, Anas bin Saif, Qasim Butt, H. Abbasi
Objective: To analyze the complexity and diversity of type, surgical management and complications in adult choledochal cysts presenting to a Hepatobiliary unit of a tertiary care hospital. Study Design: Case series. Place and Duration of Study: Pak Emirates Military Hospital Rawalpindi, from Jan 2017 to Dec 2019. Methodology: All the patients diagnosed with choledochal cyst and underwent surgical procedure between Jan 2017 to June 2019 were analyzed. The clinical features, types, operative procedure and outcomes of the patients in terms of post-operative morbidity and mortality were assessed. Calvin Dindo classification was used to assess complications. Results: A total of 17 patients were studied, out of which, 13 were females (76.5%) and 4 were males (23.5%) with mean age of 37.41 ± 16.96 years. There were 13 type I (76.5%), 2 type IVa (11.8%) and 1 type II (5.9%) choledochal cysts according to Todani’s classification. Extrahepatic cyst excision with a Roux-en-Y hepatico-jejunostomy was performed on all 17 patients. There was no mortality in the series. Post-operative complications occurred in 4 (23.5%) patients, 2 were grade II, 1 was grade I and 1 grade III according to Clavin Dindo scale. Long-term follow up revealed recurrent cholangitis in 3 (17.6%) patients which settled on antibiotic regime. The median follow up time was 1.5 years. Conclusion: The total extra-hepatic excision with Roux-en-Y hepaticojejunostomy is the treatment of choice for adult choledochal cyst. The procedure has low morbidity and very low mortality.
目的:分析某三级医院肝胆科成人胆总管囊肿的类型、手术处理及并发症的复杂性和多样性。研究设计:病例系列。学习地点和时间:2017年1月至2019年12月,巴基斯坦阿联酋拉瓦尔品第军事医院。方法:分析2017年1月至2019年6月期间所有诊断为胆总管囊肿并接受手术治疗的患者。评估患者的临床特点、类型、手术方式及术后发病率和死亡率。采用Calvin Dindo分类评估并发症。结果:共17例患者,其中女性13例(76.5%),男性4例(23.5%),平均年龄37.41±16.96岁。根据Todani分类,I型13例(76.5%),IVa型2例(11.8%),II型1例(5.9%)。所有17例患者均行肝外囊肿切除及Roux-en-Y肝空肠吻合术。这个系列中没有死亡率。术后并发症4例(23.5%),按Clavin Dindo评分,II级2例,I级1例,III级1例。长期随访发现3例(17.6%)患者复发性胆管炎,最终采用抗生素治疗。中位随访时间为1.5年。结论:肝外全切除联合Roux-en-Y肝空肠吻合术是治疗成人胆总管囊肿的首选方法。手术的发病率和死亡率都很低。
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引用次数: 1
ASSESSMENT OF SLEEP QUALITY IN PATIENTS WITH TYPE 2 DIABETES MELLITUS: A PROSPECTIVE OBSERVATIONAL STUDY FROM A TERTIARY CARE CENTRE 评估2型糖尿病患者的睡眠质量:一项来自三级保健中心的前瞻性观察研究
Pub Date : 2021-12-30 DOI: 10.51253/pafmj.v6i6.4585
Syeda Ramsha Batool, Insia Hasan, Jawed Akbar Dars, Rabisa Batool, S. M. Ahmed, M. Iqbal
Objective: To evaluate the quality of sleep-in patients diagnosed with Type 2 Diabetes Mellitus (T2DM). Study Design: Prospective observational study. Place and Duration of Duration: Psychiatry Department and Medicine Ward of Jinnah Postgraduate Medical Centre, Karachi Pakistan, from Apr to Nov 2018. Methodology: All patients with Type 2 Diabetes Mellitus were included in the study. All cases under age 30, type I diabetes, gestational diabetes and patients with severe illness were excluded. The data of sociodemographic lifestyle factors was collected through a pre-designed semi-structured questionnaire and sleep quality of patients was assessed using Pittsburg Sleep Quality Index (PSQI). The results of the data were analyzed by using SPSS version 24. Results: Out of 260 patients with Type 2 Diabetes Mellitus, 197 (76%) were female. The mean age of the sample was 55.7 ± 9.89 years, with only 54 (20.8%) having normal body mass index. More than 50% of sample was poor sleepers and educational status was found to be strongly associated with quality of sleep (p-value <0.05). Conclusion: The present study indicates that patients with Diabetes Mellitus often experienced sleep irregularities hence poor sleep quality. There is a need to increase the awareness regarding sleep quality among patients and health professionals as well while assessing the patients with Diabetes Mellitus.
目的:评价2型糖尿病(T2DM)患者的睡眠质量。研究设计:前瞻性观察性研究。地点和时间:2018年4月至11月,巴基斯坦卡拉奇真纳研究生医疗中心精神科和内科病房。方法:所有2型糖尿病患者纳入研究。排除30岁以下、1型糖尿病、妊娠期糖尿病及重症患者。采用预先设计的半结构化问卷收集社会人口生活方式因素数据,采用匹兹堡睡眠质量指数(PSQI)评估患者睡眠质量。数据结果采用SPSS version 24进行分析。结果:260例2型糖尿病患者中,女性197例(76%)。样本平均年龄为55.7±9.89岁,体重指数正常的54例(20.8%)。超过50%的样本为睡眠不良者,教育程度与睡眠质量密切相关(p值<0.05)。结论:糖尿病患者存在睡眠不规律,睡眠质量较差。在对糖尿病患者进行评估时,有必要提高患者和卫生专业人员对睡眠质量的认识。
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引用次数: 0
ROLE OF ALPHA BLOCKER IN URETERORENOSCOPY. 阻滞剂在输尿管镜检查中的作用。
Pub Date : 2021-12-30 DOI: 10.51253/pafmj.v6i6.5647
A. Nadeem, Noreen Anwar, N. Ahmed, Yasser Saeed Khan, Irum Rashid, M. Ali
Objective: To determine the efficacy of alpha blockers in successful management of lower and mid ureteral stones by ureterorenoscopy. Study Design: Comparative prospective study. Place and Duration of Study: Department of Urology, Combined Military Hospital Quetta Pakistan, from Jul 2018 to Dec 2019. Methodology: Total of 150 patients having mid and lower ureteric calculi requiring ureterorenoscopy were divided into two groups. Group A included patients without pre-treatment with alpha blocker was administered before they were subjected to ureterorenoscopy. Study group B included patients who received daily oral dose of alpha blocker, Tamsulosin 0.4 mg twice daily, for 1 week before ureterorenoscopy. Per-operative findings in both the groups were recorded. Results were analyzed by comparing the outcome between both groups in terms of ease of performing procedure, duration of procedure, complications, duration of hospital stay and need for stent placement. Results: Mean operative time was significantly shorter in group B as compared to group A, (15.9 ± 3.81 min vs. 21.9 ± 3.63 min; p≤0.001). Demographic and stone characteristics were comparable between the both groups. Success rate was 74 (98.7%), in group B as compared to 68 (90.7%) in group A, with statistically significant difference (p=0.020). Complications in group B were less frequent 1 (1.3%) vs 7 (9.3%) in group A (p-value=0.027). Conclusion: Use of alpha blockers for one week before performing ureterorenoscopy resulted in fewer complications and made the procedure easier to perform as well.
目的:探讨α受体阻滞剂在输尿管镜下成功治疗输尿管中下部结石的疗效。研究设计:比较前瞻性研究。学习地点和时间:2018年7月至2019年12月,巴基斯坦奎达联合军队医院泌尿外科。方法:将150例输尿管中下段结石需要输尿管镜检查的患者分为两组。A组患者在接受输尿管镜检查前未进行α受体阻滞剂预处理。研究B组患者在输尿管镜检查前接受每日口服剂量的α受体阻滞剂坦索罗辛0.4 mg,每日两次,持续1周。记录两组患者术中表现。比较两组患者在手术难易程度、手术时间、并发症、住院时间和支架放置需求等方面的结果。结果:B组平均手术时间明显短于A组(15.9±3.81 min vs 21.9±3.63 min);p≤0.001)。两组之间的人口统计学和结石特征具有可比性。B组治疗成功率为74例(98.7%),A组为68例(90.7%),差异有统计学意义(p=0.020)。B组并发症发生率为1例(1.3%),A组为7例(9.3%)(p值=0.027)。结论:输尿管镜检查前使用α受体阻滞剂一周,并发症少,操作方便。
{"title":"ROLE OF ALPHA BLOCKER IN URETERORENOSCOPY.","authors":"A. Nadeem, Noreen Anwar, N. Ahmed, Yasser Saeed Khan, Irum Rashid, M. Ali","doi":"10.51253/pafmj.v6i6.5647","DOIUrl":"https://doi.org/10.51253/pafmj.v6i6.5647","url":null,"abstract":"Objective: To determine the efficacy of alpha blockers in successful management of lower and mid ureteral stones by ureterorenoscopy. \u0000Study Design: Comparative prospective study. \u0000Place and Duration of Study: Department of Urology, Combined Military Hospital Quetta Pakistan, from Jul 2018 to Dec 2019. \u0000Methodology: Total of 150 patients having mid and lower ureteric calculi requiring ureterorenoscopy were divided into two groups. Group A included patients without pre-treatment with alpha blocker was administered before they were subjected to ureterorenoscopy. Study group B included patients who received daily oral dose of alpha blocker, Tamsulosin 0.4 mg twice daily, for 1 week before ureterorenoscopy. Per-operative findings in both the groups were recorded. Results were analyzed by comparing the outcome between both groups in terms of ease of performing procedure, duration of procedure, complications, duration of hospital stay and need for stent placement. \u0000Results: Mean operative time was significantly shorter in group B as compared to group A, (15.9 ± 3.81 min vs. 21.9 ± 3.63 min; p≤0.001). Demographic and stone characteristics were comparable between the both groups. Success rate was 74 (98.7%), in group B as compared to 68 (90.7%) in group A, with statistically significant difference (p=0.020). Complications in group B were less frequent 1 (1.3%) vs 7 (9.3%) in group A (p-value=0.027). \u0000Conclusion: Use of alpha blockers for one week before performing ureterorenoscopy resulted in fewer complications and made the procedure easier to perform as well.","PeriodicalId":19982,"journal":{"name":"PAFMJ","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82432219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COMPARISON OF NUTRITIONAL STATUS OF DOCTORS IN SERVICES HOSPITALS WITH THAT OF EQUIVALENT SOCIAL STRATA IN RELATION TO THEIR EATING HABITS AND PHYSICAL ACTIVITY 服务医院医生与同等社会阶层医生营养状况与饮食习惯和体育活动的比较
Pub Date : 2021-12-30 DOI: 10.51253/pafmj.v6i6.7224
A. M. Sukhera, R. Roshan, S. Sajjad, S. Tanvir, Syed Fawad Mashhadi
Objective: To compare the nutritional status of doctors and non-doctors in relation to their eating habits and physical activity Study Design: Cross sectional study. Place and Duration of Study: Combined Military Hospital/Military Hospital Rawalpindi, from Sep 2018 to Mar 2019. Methodology: Anthropometric measurements like weight for age, height for age, weight according to height along with BMI were used as indicators of nutritional status. Data collection tool was built upon food frequency questionnaire and comprised of sociodemographic variables followed by major portions related to general health of respondents, nutritional assessment, dietary patterns and physical activity. Results: Out of 200 respondents, 100 were physicians working in services hospitals of Army while rest hundred were serving officers non-doctors of similar social status. Mean age of the participants was 35.00 ± 7.57 years. There was no significant difference between self-perceived health status of both groups (p>0.05). Dietary habits of physicians were significantly healthy as compared to their counterparts (p=0.01) while physical activity patterns were better amongst non-doctors (p=0.001). Physicians had unhealthy dietary habits, but intake was bit less and cautious as compared to their counterpart group. Conclusion: Doctors have better dietary patterns, but worse physical activity practices as compared to individuals with similar social strata. Risk factors and nutritional indicators were not different for both groups.
目的:比较医生和非医生的营养状况与饮食习惯和身体活动的关系研究设计:横断面研究。学习地点和时间:2018年9月至2019年3月,拉瓦尔品第军队医院/军队医院联合医院。方法:采用年龄体重、年龄身高、身高体重和BMI等人体测量指标作为营养状况的指标。数据收集工具建立在食物频率问卷的基础上,由社会人口变量组成,其次是与受访者的一般健康、营养评估、饮食模式和身体活动相关的主要部分。结果:200名被调查者中有100人是军队服务医院的医生,其余100人是社会地位相近的在职军官。参与者平均年龄为35.00±7.57岁。两组患者自我感知健康状况差异无统计学意义(p>0.05)。医生的饮食习惯比他们的同行健康得多(p=0.01),而非医生的身体活动模式更好(p=0.001)。医生有不健康的饮食习惯,但与同行相比,他们的摄入量更少,也更谨慎。结论:与相同社会阶层的个体相比,医生有更好的饮食模式,但更差的体育锻炼习惯。两组的危险因素和营养指标没有差异。
{"title":"COMPARISON OF NUTRITIONAL STATUS OF DOCTORS IN SERVICES HOSPITALS WITH THAT OF EQUIVALENT SOCIAL STRATA IN RELATION TO THEIR EATING HABITS AND PHYSICAL ACTIVITY","authors":"A. M. Sukhera, R. Roshan, S. Sajjad, S. Tanvir, Syed Fawad Mashhadi","doi":"10.51253/pafmj.v6i6.7224","DOIUrl":"https://doi.org/10.51253/pafmj.v6i6.7224","url":null,"abstract":"Objective: To compare the nutritional status of doctors and non-doctors in relation to their eating habits and physical activity \u0000Study Design: Cross sectional study. \u0000Place and Duration of Study: Combined Military Hospital/Military Hospital Rawalpindi, from Sep 2018 to Mar 2019. \u0000Methodology: Anthropometric measurements like weight for age, height for age, weight according to height along with BMI were used as indicators of nutritional status. Data collection tool was built upon food frequency questionnaire and comprised of sociodemographic variables followed by major portions related to general health of respondents, nutritional assessment, dietary patterns and physical activity. \u0000Results: Out of 200 respondents, 100 were physicians working in services hospitals of Army while rest hundred were serving officers non-doctors of similar social status. Mean age of the participants was 35.00 ± 7.57 years. There was no significant difference between self-perceived health status of both groups (p>0.05). Dietary habits of physicians were significantly healthy as compared to their counterparts (p=0.01) while physical activity patterns were better amongst non-doctors (p=0.001). Physicians had unhealthy dietary habits, but intake was bit less and cautious as compared to their counterpart group. \u0000Conclusion: Doctors have better dietary patterns, but worse physical activity practices as compared to individuals with similar social strata. Risk factors and nutritional indicators were not different for both groups.","PeriodicalId":19982,"journal":{"name":"PAFMJ","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82576370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE SURVIVAL RATE OF CHICK EMBRYO INFLUENCED BY NICOTINE AND ANTIOXIDANT GREEN TEA (CAMELLIA SINENSIS) 烟碱和抗氧化绿茶对鸡胚成活率的影响
Pub Date : 2021-12-30 DOI: 10.51253/pafmj.v6i6.6462
Ma Shan, Shazia Muazam, Hina Shan, Fahad Atta, Zubia Iftikhar, A. Khalil
Objectives: To study the effects of Nicotine on the survival rate of chick embryo and to evaluate the preventive role by the antioxidant green tea camellia sinensis. Study Design: Laboratory-based experimental study. Place and Duration of Study: Army Medical College, Rawalpindi, from Nov 2011 to Nov 2012. Methodology: A total of 75 Fayoumi fresh fertilized eggs were kept at Poultry Research Institute, Rawalpindi. Experimental solutions were injected to the eggs of four groups at forty-eight hours of incubation and the effect on the growth was recorded and compared with the control group. The control and experimental groups were observed to assess the effects of Nicotine and the role of antioxidant green tea Camellia sinensis on the survival rate and growth of chick embryo’s femur. Results: The control group (group-1) showed 100% survival rate of embryos. The experimental group-2 showed survival rate of 100% embryos and the group-3 and group-4 showed survival rate 50% and 70% of embryos, respectively. Conclusion: It was concluded that green tea decreases the oxidative stress caused by the Nicotine.
目的:研究烟碱对鸡胚成活率的影响,并评价抗氧化绿茶茶树的预防作用。研究设计:基于实验室的实验研究。学习地点和时间:2011年11月至2012年11月,拉瓦尔品第陆军医学院。方法:在拉瓦尔品第家禽研究所饲养75只法尤米新鲜受精卵。在孵育48 h时,将实验溶液注射到四组鸡蛋中,记录对鸡蛋生长的影响,并与对照组进行比较。采用对照组和试验组分别观察烟碱和抗氧化绿茶山茶对鸡胚股骨成活率和生长的影响。结果:对照组(1组)胚胎成活率100%。实验2组胚胎存活率为100%,3组和4组胚胎存活率分别为50%和70%。结论:绿茶可降低烟碱引起的氧化应激。
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引用次数: 0
NEGATIVE APPENDECTOMIES ARE MORE COMMON IN FEMALES OF REPRODUCTIVE AGE GROUP 阴性阑尾切除术多见于育龄女性
Pub Date : 2021-12-30 DOI: 10.51253/pafmj.v6i6.4630
Z. Ali, M. R. Khan, R. Memon, I. Ujjan, Fida Hussain, Zainab Nisar
Objective: To compare the negative appendectomy in the females of reproductive and non-reproductive age groups. Study Design: Cross-sectional study. Place and Duration of Study: Department of Pathology, Diagnostic and Research Laboratory, Liaquat University of Medical and Health Sciences, Hyderabad, Pakistan, from January 2018 to December 2019. Methodology: A total of 1126 appendectomy specimens were enrolled irrespective of age and gender. The biodata of patients was retrieved from the database. Statistical analysis was done using SPSS version 22. Results: Out of total 1126 reported cases, 787 (69.9%) were males and 339 (30.1%) were females. The mean age was calculated to be 24.43 ± 12.42 years ranging from 2-94 years. Histopathological examination revealed cases of acute appendicitis 374 (33.2%), acute appendicitis with peri-appendicitis 478 (42.5%), fibrous obliteration 28 (2.5%) and parasitic infestation 7 (0.6%). Overall negative appendectomies were 219 (19.4%) and were prominent in females 100 (29.5%) than males 119 (15.1%). Also it was higher in females of reproductive age group 77 (30.4%) than in non-reproductive age group 23 (27.9%). Conclusion: In our study negative appendectomy in females of reproductive age groups was found to be higher than expected. Clinical scoring systems, biochemical markers, imaging modalities, and second opinion from other specialties like internal medicine, gynae and obstetric have been introduced to substantiate the diagnosis of acute appendicitis and thereby decreases the negative appendectomy.
目的:比较育龄期和非育龄期女性阑尾切除术阴性的效果。研究设计:横断面研究。学习地点和时间:2018年1月至2019年12月,巴基斯坦海得拉巴利亚奎特医学与健康科学大学病理科诊断与研究实验室。方法:不考虑年龄和性别,共纳入1126例阑尾切除术标本。从数据库中检索患者的生物数据。采用SPSS 22进行统计分析。结果:1126例病例中,男性787例(69.9%),女性339例(30.1%)。平均年龄24.43±12.42岁,年龄范围2 ~ 94岁。组织病理学检查显示急性阑尾炎374例(33.2%),急性阑尾炎伴阑尾周围炎478例(42.5%),纤维闭塞28例(2.5%),寄生虫感染7例(0.6%)。阑尾切除术阴性219例(19.4%),女性100例(29.5%)高于男性119例(15.1%)。育龄组77(30.4%)高于非育龄组23(27.9%)。结论:本研究发现育龄女性阑尾切除术阴性的比例高于预期。临床评分系统、生化标记物、影像模式以及内科、妇科和产科等其他专业的第二意见已被引入,以证实急性阑尾炎的诊断,从而减少阑尾切除术的阴性。
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引用次数: 0
PERCEPTIONS OF TRAINEES ABOUT USE OF SIMULATION IN GYNAECOLOGY AND OBSTETRICS 受训者对妇产科使用模拟的看法
Pub Date : 2021-12-30 DOI: 10.51253/pafmj.v6i6.4277
Maimoona Hafeez, N. Sohail, S. Waqar
Objective: To explore the perception of Obstetrics and Gynaecology (OB/GYN) postgraduates about the use of simulation in improving their clinical skills. Study Design: Explanatory sequential mixed method design. Place and Duration of Study: Obstetrics and Gynaecology department of Sharif Medical and Dental City (SMDC) Lahore Pakistan, from Jun to Oct 2019. Methodology: By using a homogenous purposive sampling technique eight postgraduate residents from Obstetrics and Gynaecology department were recruited. The study had two phases: In the first phase, quantitative data was collected and analyzed while in the second phase qualitative data were collected by following the quantitative phase and then analyzed. This framework was tracked through the procedure of instrumental delivery with vacuum application in a real-life situation. A survey was conducted before and after the simulation training by using a researcher-developed Likert scale questionnaire. After that in-depth qualitative interviews were conducted. The improvement in clinical performance was evaluated by pairedsample t-test and thematic analysis. Results: Significant performance improvement (p<0.001) after simulation training was reported. The thematic analysis revealed a lack of proficiency in clinical experience before simulation at behavioural and technical levels while enhancement in clinical experience after simulation at both levels. The perceived benefits of simulation with the major trends of simulation as time-friendly, as a source of deliberate practice, and as safe practice in the unthreatened environment were explored. The theme of suggestions was also explored. Conclusion: The participants showed improvement in their clinical skills by describing the optimized benefits of simulation. Few of them are.......
目的:探讨妇产科研究生对运用模拟教学提高临床技能的看法。研究设计:解释顺序混合方法设计。学习地点和时间:2019年6月至10月,巴基斯坦拉合尔谢里夫医疗和牙科城(SMDC)妇产科。方法:采用同质目的抽样方法,从妇产科招募8名研究生住院医师。本研究分为两个阶段,第一阶段是定量数据的收集和分析,第二阶段是定性数据的收集,跟随定量阶段进行分析。该框架通过在现实生活中真空应用的仪器输送过程进行跟踪。采用研究者自行开发的李克特量表问卷,在模拟训练前后进行问卷调查。之后进行了深入的定性访谈。通过配对样本t检验和专题分析评估临床表现的改善情况。结果:模拟训练后患者表现有显著改善(p<0.001)。专题分析显示,在行为和技术层面模拟之前,临床经验缺乏熟练程度,而在两个层面模拟之后,临床经验都有所增强。模拟的主要趋势是时间友好,作为刻意练习的来源,以及在无威胁的环境中安全练习,探索了模拟的感知好处。还探讨了建议的主题。结论:通过描述模拟的最佳益处,参与者表现出临床技能的提高。他们中很少有人是.......
{"title":"PERCEPTIONS OF TRAINEES ABOUT USE OF SIMULATION IN GYNAECOLOGY AND OBSTETRICS","authors":"Maimoona Hafeez, N. Sohail, S. Waqar","doi":"10.51253/pafmj.v6i6.4277","DOIUrl":"https://doi.org/10.51253/pafmj.v6i6.4277","url":null,"abstract":"Objective: To explore the perception of Obstetrics and Gynaecology (OB/GYN) postgraduates about the use of simulation in improving their clinical skills. \u0000Study Design: Explanatory sequential mixed method design. \u0000Place and Duration of Study: Obstetrics and Gynaecology department of Sharif Medical and Dental City (SMDC) Lahore Pakistan, from Jun to Oct 2019. \u0000Methodology: By using a homogenous purposive sampling technique eight postgraduate residents from Obstetrics and Gynaecology department were recruited. The study had two phases: In the first phase, quantitative data was collected and analyzed while in the second phase qualitative data were collected by following the quantitative phase and then analyzed. This framework was tracked through the procedure of instrumental delivery with vacuum application in a real-life situation. A survey was conducted before and after the simulation training by using a researcher-developed Likert scale questionnaire. After that in-depth qualitative interviews were conducted. The improvement in clinical performance was evaluated by pairedsample t-test and thematic analysis. \u0000Results: Significant performance improvement (p<0.001) after simulation training was reported. The thematic analysis revealed a lack of proficiency in clinical experience before simulation at behavioural and technical levels while enhancement in clinical experience after simulation at both levels. The perceived benefits of simulation with the major trends of simulation as time-friendly, as a source of deliberate practice, and as safe practice in the unthreatened environment were explored. The theme of suggestions was also explored. \u0000Conclusion: The participants showed improvement in their clinical skills by describing the optimized benefits of simulation. Few of them are.......","PeriodicalId":19982,"journal":{"name":"PAFMJ","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87730290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thalassemia ENDOCRINOPATHIES IN THALASSEMIA PATIENTS 地中海贫血患者的内分泌病变
Pub Date : 2021-12-30 DOI: 10.51253/pafmj.v6i6.4778
U. Touheed, Samra Maryam, Hafiz Muhammad Murtaza, Muhammad Mujtaba Sabir, Lutfullah Goheer, A. Awan
Objective: To determine the common endocrine complications found in children having thalassemia major. Study Design: Cross-sectional study. Place and Duration of Study: Department of Pediatric Medicine, Combined Military Hospital Multan, from May to Nov 2019. Methodology: A total of 160 Children with thalassemia were taken in this study. Once registered, venous blood sample was taken and sent to the laboratory for endocrine profile. SPSS-21 was applied for analysis of collected data. Results: Out of 160 study cases, 100 (62.5%) were boys while 60 (37.5%) were female patients. Mean age of our study cases was 8.58 ± 1.98 years. Mean duration of disease was 5.28 ± 3.29 years. Parental consanguinity was positive in 122 (76.3%) and only 47 (29.4%) were taking chelation therapy. Mean HbA1C level was 6.23 ± 1.18% mg/dl and diabetes was noted in 41 (25.6%) of our study cases. Mean FT4 was 0.98 ± 0.13 ng/dl and hypothyroidism was noted in 24 (15%) of our study cases. Conclusion: Diabetes and hypothyroidism were the common endocrine complications noted in our study among children having thalassemia. All physicians treating such patients should always screen such patients for early diagnosis and timely management in order to reduce burden of related morbidities and enhance quality of life of these patients.
目的:探讨小儿重度地中海贫血常见的内分泌并发症。研究设计:横断面研究。学习地点及时间:木尔坦联合军医院儿科,2019年5月- 11月。方法:本研究共收集了160例地中海贫血儿童。登记后,采集静脉血送到实验室进行内分泌分析。采用SPSS-21软件对收集的数据进行分析。结果:160例患者中,男性100例(62.5%),女性60例(37.5%)。我们研究病例的平均年龄为8.58±1.98岁。平均病程5.28±3.29年。亲本系阳性122例(76.3%),接受螯合治疗的仅有47例(29.4%)。平均HbA1C水平为6.23±1.18% mg/dl,在我们的研究病例中有41例(25.6%)患有糖尿病。平均FT4为0.98±0.13 ng/dl, 24例(15%)出现甲状腺功能减退。结论:糖尿病和甲状腺功能减退是我们研究中发现的地中海贫血儿童常见的内分泌并发症。所有治疗此类患者的医生都应经常对此类患者进行筛查,以便早期诊断和及时管理,以减轻相关发病率的负担,提高患者的生活质量。
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