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Un caso raro de linfangioma quístico del cuello en un paciente adulto 成人患者罕见的囊性颈部淋巴瘤
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-03-01 Epub Date: 2026-02-26 DOI: 10.1016/j.rce.2026.502490
M. Colangeli , M. Palmas , P. Spinnato
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引用次数: 0
Situación actual y papel de los internistas en los comités de ética asistencial en España. Estudio PANACEAS 西班牙医疗伦理委员会的现状和医生的作用。研究的
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-03-01 Epub Date: 2026-02-17 DOI: 10.1016/j.rce.2026.502483
P. Durán del Campo , G. Solano Iturri , B. Alonso Ortiz , J. Bertran Muñoz , A.M. Bravo Blanco , L. Briongos Figuero , C. Carrera García , A.D. Chacón Moreno , A. Blanco Portillo , J.M. Galván-Román , como miembros del Grupo de Trabajo de Bioética y Profesionalismo de la Sociedad Española de Medicina Interna

Objectives

To analyze the current situation of Healthcare Ethics Committees (HECs) in Spain, their composition and functions, as well as the implementation of Clinical Ethics Consultancy (CEC). Finally, to assess the involvement of internists in HECs.

Materials and methods

A cross-sectional descriptive study conducted through a self-administered online survey distributed between February and May 2025 to all identified HECs in the country.

Results

A total of 112 HECs (47.66%) out of the 235 accredited nationwide participated. The average number of members per committee was 16 (range: 6-29). The most represented professional profiles were nursing and medicine. In 99.1% of the committees, at least one member had postgraduate training in Bioethics. The most frequent range of meetings per year was between 7 and 12 (46.8%). Most HECs (91.1%) were involved in educational activities, and 58% had produced ethical documents. The majority reviewed between 1 and 5 cases annually (69.6%). The CEC role was established in 40.2% of HECs and in the process of implementation in 18.8%. Internists were present in 54% of HECs. In 65% of cases, the internist is part of the CEC.

Conclusions

HECs in Spain demonstrate significant involvement in educational activities and the development of ethical documents; however, they receive a relatively low number of annual consultations. CEC is gradually being integrated into the structure of HECs, which may enhance the management of ethical inquiries. Internists are members of more than half of the HECs and play a very active role in their operations.
目的分析西班牙医疗伦理委员会(HECs)的现状、组成和职能,以及临床伦理咨询(CEC)的实施情况。最后,评估内科医生参与高等专科医院的情况。材料和方法通过一项自我管理的在线调查进行了一项横断面描述性研究,该调查于2025年2月至5月期间向全国所有确定的hec分发。结果在全国235家经认证的高等学校中,共有112家(47.66%)参与。每个委员会的平均成员人数为16人(范围:6-29人)。最具代表性的专业是护理和医学。在99.1%的委员会中,至少有一名成员接受过生物伦理学研究生培训。每年最频繁的会议范围是7至12次(46.8%)。大多数高等学校(91.1%)参与了教育活动,58%的高等学校制定了伦理文件。大多数病例每年复查1 - 5例(69.6%)。40.2%的高等教育中心确立了中央协调委员会的作用,18.8%的高等教育中心处于执行过程中。内科医生出现在54%的hec中。在65%的病例中,内科医生是CEC的一部分。西班牙的高等教育伦理委员会积极参与教育活动和道德文件的制定;但是,他们每年接受的咨询次数相对较少。伦理委员会正逐渐纳入高等教育委员会的结构,这可能会加强对道德调查的管理。内科医生是超过一半的高等医疗保健委员会的成员,在这些委员会的运作中发挥着非常积极的作用。
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引用次数: 0
Tratamiento basal con betabloqueantes e inhibidores del sistema renina angiotensina y su asociación con eventos adversos en insuficiencia cardíaca aguda β受体阻滞剂和肾血管紧张素抑制剂的基础治疗及其与急性心力衰竭不良事件的关联
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-03-01 Epub Date: 2026-02-24 DOI: 10.1016/j.rce.2026.502487
A. Haro , J. Jacob , X. Rossello , A. Alquézar-Arbe , P. Llorens , Ò. Miró , en representación del grupo Icasemes

Introduction

Baseline treatment with beta-blockers (BB) and/or renin-angiotensin system inhibitors (RASi) has been extensively studied in the context of heart failure, given its fundamental role in modulating the neurohormonal axis and improving survival.

Objective

To investigate whether there is an association between receiving baseline treatment with BB or RASi, either alone or in combination, and the short-term prognosis of an episode of acute heart failure (AHF).

Method

Patients from the EAHFE registry (Epidemiology of Acute Heart Failure in Spanish Emergency Departments) were analyzed. This is a multicenter, prospective, multipurpose registry that collects all AHF episodes presenting to participating hospital emergency departments over a period of 1 to 2 months between 2007 and 2018. The primary outcome variable investigated was in-hospital all-cause mortality during the emergency departments stay or hospitalization. Adjusted analyses were conducted using multiple logistic regression and multiple imputation to control for potential confounding factors.

Results

The study included a total of 17,916 episodes of AHF. A total of 26.2% of patients did not receive treatment with either BB or RASi, constituting the reference group. Overall, 17.8% of patients received BB only, 30.4% were treated exclusively with RASi, and 25.7% received a combination of both drugs. The mean age of the patients was 80.4 years (standard deviation 10.2 years), and 55.7% were women. In-hospital mortality was 7.3%. After multivariable adjustment, a significant association with lower mortality was found for treatment with BB alone (odds ratio [OR] = 0.826, 95% confidence interval [CI]: 0.685-0.996), OR = 0.709 (95%CI: 0.600-0.837) RASi alone and for combined treatment with RASi and BB (OR = 0.699, 95%CI: 0.580-0.843). In the adjusted model with multiple imputation, the results remained significant.

Conclusions

In patients with an episode of AHF, baseline treatment with BB, RASi, or both is associated with lower all-cause mortality. This association is strongest in the group of patients receiving both treatments combined, and the results remain significant after multivariate adjustment.
鉴于β受体阻滞剂(BB)和/或肾素-血管紧张素系统抑制剂(RASi)在调节神经激素轴和提高生存率方面的基本作用,在心力衰竭的背景下,已经广泛研究了β受体阻滞剂(BB)和/或肾素血管紧张素系统抑制剂(RASi)的基线治疗。目的探讨基线治疗中接受BB或RASi(单独或联合)与急性心力衰竭(AHF)发作的短期预后之间是否存在关联。方法对西班牙急诊科急性心力衰竭流行病学(EAHFE)登记的患者进行分析。这是一个多中心、前瞻性、多用途的登记,收集了2007年至2018年1至2个月期间在参与医院急诊科就诊的所有AHF事件。调查的主要结局变量是急诊科住院或住院期间的院内全因死亡率。采用多元逻辑回归和多元归算进行校正分析,以控制潜在的混杂因素。结果本研究共纳入AHF 17916例。26.2%的患者未接受BB或RASi治疗,构成参照组。总体而言,17.8%的患者仅接受BB治疗,30.4%的患者仅接受RASi治疗,25.7%的患者接受两种药物联合治疗。患者平均年龄80.4岁(标准差10.2岁),女性55.7%。住院死亡率为7.3%。多变量调整后,单用BB治疗与较低的死亡率显著相关(优势比[OR] = 0.826, 95%可信区间[CI]: 0.685-0.996),单用RASi治疗与联合用RASi和BB治疗(OR = 0.699, 95%可信区间[CI]: 0.600-0.837)。在多次插值调整后的模型中,结果仍然显著。结论在AHF发作的患者中,基线治疗BB、RASi或两者兼有可降低全因死亡率。这种相关性在同时接受两种治疗的患者组中最强,并且在多因素调整后结果仍然显著。
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引用次数: 0
¿Inicio de inhibidores del cotransportador de sodio-glucosa tipo 2 (iSGLT2) en pacientes con insuficiencia cardiaca aguda en urgencias? 2型钠-葡萄糖共转运抑制剂(iSGLT2)在急性心力衰竭急诊患者中的启动?
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-03-01 Epub Date: 2026-02-23 DOI: 10.1016/j.rce.2026.502470
P. Herrero-Puente , Á. González Franco
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引用次数: 0
Metodología GRADE en los consensos y guías de práctica clínica para el manejo de la oclusión venosa retiniana 视网膜静脉闭塞管理的分级共识方法和临床实践指南
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-03-01 Epub Date: 2026-02-16 DOI: 10.1016/j.rce.2026.502469
C. Burgueño-Montañes , R. Bouchikh-El Jarroudi , M. Zavaleta-Mercado , J. Galvez-Olortegui
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引用次数: 0
Consultas en urgencias de los pacientes mayores que viven con VIH: una aproximación a partir del registro EDEN 老年艾滋病毒携带者的急诊咨询:基于EDEN数据库的方法
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-03-01 Epub Date: 2026-02-16 DOI: 10.1016/j.rce.2026.502474
Ò. Miró , L. Sentís , M. Carbó , E. Miró , D. Mérida , J. González del Castillo , (en representación del grupo SIESTA)

Objective

To investigate the incidence, sociodemographic characteristics, baseline status and evolution of elderly people living with Human immunodeficiency virus (HIV) infection (PLHIV) attended in Spanish hospital emergency departments (ED).

Methods

Patients included in the EDEN (Emergency Department and Elder Needs) registry, which includes all patients aged 65 or older attended in 52 Spanish EDs during 7 consecutive days in 2019, were analyzed. Two groups were constructed according to whether or not they had known HIV infection (PLHIV and non-LHIV). We collected 6 sociodemographic factors and 8 referring to the patient's baseline situation. We recorded whether the episode of ED care required hospitalization, intensive care unit (ICU) admission, prolonged ED and inpatient stay, and in-hospital mortality, as well as reconsultation to the ED, rehospitalization, and death from any cause during the 3 years after discharge. The sociodemographic and baseline characteristics and the evolution of patients in the PLHIV and non-PLHIV groups were compared.

Results

Of 25,557 patients in the EDEN registry, 78 were PLHIV (0.30%, 95% CI 0.24% to 0.38%). The annual ED frequentation rate of PLHIV and non-PVHIV was 811 and 573 per 1000 population, respectively. The sociodemographic and baseline conditions were similar between PLHIV and non-PLHIV, with only age differing (younger PLHIV). Older PLHIV had severe comorbidity (27%), some type of functional limitation (27%) and cognitive impairment (11%). The most frequent ED diagnoses in PLHIV were pneumonia or lower respiratory tract infection (11%), heart failure or cardiogenic shock (8%) and joint and axial pain (6%), and in the non-HIV group there were no new diagnoses of HIV infection. 24.4% of PLHIV were hospitalized, 27.3% had a prolonged stay in the ED, 50% had prolonged hospitalization, 7.7% had in-hospital mortality, and reconsultation to the ED, hospitalization, and death during the 3 years post-discharge were 67%, 45.6%, and 21.7%, respectively. No outcome differed between PLHIV and non-PLHIV.

Conclusion

Older PLHIV have sociodemographic and baseline characteristics like the general population, but their rate of ED visits is higher. The severity of the episodes leading to this ED consultation is similar between PLHIV and non-PLHIV and long-term follow-up also shows no differences.
目的调查西班牙医院急诊科(ED)老年人HIV感染(PLHIV)的发生率、社会人口学特征、基线状况及演变。方法分析EDEN(急诊科和老年人需求)登记处的患者,其中包括2019年连续7天在52个西班牙急诊科就诊的所有65岁及以上患者。根据是否已知HIV感染分为PLHIV和non-LHIV两组。我们收集了6个社会人口学因素和8个涉及患者基线情况的因素。我们记录了在出院后的3年内,急诊科的发作是否需要住院、重症监护病房(ICU)入院、延长急诊科和住院时间、住院死亡率、再咨询急诊科、再住院和任何原因死亡。比较PLHIV组和非PLHIV组患者的社会人口学特征和基线特征及其演变。结果在EDEN登记的25557例患者中,78例为PLHIV (0.30%, 95% CI 0.24%至0.38%)。PLHIV和非pvhiv的ED年发病率分别为811 / 1000和573 / 1000。PLHIV和非PLHIV之间的社会人口学和基线条件相似,只是年龄不同(年轻的PLHIV)。老年PLHIV患者有严重的合并症(27%),某种类型的功能限制(27%)和认知障碍(11%)。PLHIV患者中最常见的ED诊断为肺炎或下呼吸道感染(11%)、心力衰竭或心源性休克(8%)、关节和轴性疼痛(6%),而非HIV组中没有新的HIV感染诊断。24.4%的PLHIV患者住院,27.3%的患者在急诊科长时间住院,50%的患者长时间住院,7.7%的患者住院死亡,出院后3年内再诊、住院和死亡的比例分别为67%、45.6%和21.7%。PLHIV和非PLHIV之间没有结果差异。结论老年hiv患者具有与普通人群相似的社会人口学特征和基线特征,但急诊科就诊率较高。在PLHIV和非PLHIV患者中,导致ED会诊的发作的严重程度相似,长期随访也没有差异。
{"title":"Consultas en urgencias de los pacientes mayores que viven con VIH: una aproximación a partir del registro EDEN","authors":"Ò. Miró ,&nbsp;L. Sentís ,&nbsp;M. Carbó ,&nbsp;E. Miró ,&nbsp;D. Mérida ,&nbsp;J. González del Castillo ,&nbsp;(en representación del grupo SIESTA)","doi":"10.1016/j.rce.2026.502474","DOIUrl":"10.1016/j.rce.2026.502474","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the incidence, sociodemographic characteristics, baseline status and evolution of elderly people living with Human immunodeficiency virus (HIV) infection (PLHIV) attended in Spanish hospital emergency departments (ED).</div></div><div><h3>Methods</h3><div>Patients included in the EDEN (Emergency Department and Elder Needs) registry, which includes all patients aged 65 or older attended in 52 Spanish EDs during 7 consecutive days in 2019, were analyzed. Two groups were constructed according to whether or not they had known HIV infection (PLHIV and non-LHIV). We collected 6 sociodemographic factors and 8 referring to the patient's baseline situation. We recorded whether the episode of ED care required hospitalization, intensive care unit (ICU) admission, prolonged ED and inpatient stay, and in-hospital mortality, as well as reconsultation to the ED, rehospitalization, and death from any cause during the 3 years after discharge. The sociodemographic and baseline characteristics and the evolution of patients in the PLHIV and non-PLHIV groups were compared.</div></div><div><h3>Results</h3><div>Of 25,557 patients in the EDEN registry, 78 were PLHIV (0.30%, 95% CI 0.24% to 0.38%). The annual ED frequentation rate of PLHIV and non-PVHIV was 811 and 573 per 1000 population, respectively. The sociodemographic and baseline conditions were similar between PLHIV and non-PLHIV, with only age differing (younger PLHIV). Older PLHIV had severe comorbidity (27%), some type of functional limitation (27%) and cognitive impairment (11%). The most frequent ED diagnoses in PLHIV were pneumonia or lower respiratory tract infection (11%), heart failure or cardiogenic <em>shock</em> (8%) and joint and axial pain (6%), and in the non-HIV group there were no new diagnoses of HIV infection. 24.4% of PLHIV were hospitalized, 27.3% had a prolonged stay in the ED, 50% had prolonged hospitalization, 7.7% had in-hospital mortality, and reconsultation to the ED, hospitalization, and death during the 3 years post-discharge were 67%, 45.6%, and 21.7%, respectively. No outcome differed between PLHIV and non-PLHIV.</div></div><div><h3>Conclusion</h3><div>Older PLHIV have sociodemographic and baseline characteristics like the general population, but their rate of ED visits is higher. The severity of the episodes leading to this ED consultation is similar between PLHIV and non-PLHIV and long-term follow-up also shows no differences.</div></div>","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":"226 3","pages":"Article 502474"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147428022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
El efecto de la edad en la precisión de los criterios de Light 年龄对Light标准准确度的影响
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-03-01 Epub Date: 2026-02-28 DOI: 10.1016/j.rce.2026.502486
W.-Q. Zheng , S. Bielsa , Y. Niu , J.-X. Wen , L. Yan , Z.-D. Hu , J.M. Porcel

Objective

This study aimed to investigate the effects of age on the sensitivity, specificity, and accuracy of Light's criteria to differentiate exudative from transudative pleural effusion.

Methods

A testing cohort from China and a validation cohort from Spain were used for data analysis. The testing cohort included 302 patients (59 transudates and 243 exudates) with undiagnosed pleural effusion. The validation cohort comprised 400 patients (200 transudates and 200 exudates) divided into two groups according to age (200 patients aged 50-65 years and 200 patients aged 80-95 years). The effects of age on the sensitivity, specificity, and accuracy of Light's criteria were determined by sampling patients with different age limits.

Results

In the testing cohort, the sensitivity and specificity of Light's criteria for exudate were 0.91 and 0.73, respectively. In the validation cohort, the sensitivity was 0.99 and 0.97, and the specificity of Light's criteria for exudate was 0.73 and 0.68, respectively, by age group. The diagnostic accuracy metrics (sensitivity, specificity, and accuracy) of Light's criteria and its items tended to decrease with age.

Conclusion

Age should be considered when interpreting the Light's criteria.
目的探讨年龄对Light鉴别渗出性胸腔积液和透出性胸腔积液的敏感性、特异性和准确性的影响。方法采用来自中国的检验队列和来自西班牙的验证队列进行数据分析。试验队列包括302例未确诊的胸腔积液患者(59例渗出患者和243例渗出患者)。验证队列包括400例患者(200例转体和200例渗出),按年龄分为两组(200例50-65岁和200例80-95岁)。年龄对Light标准的敏感性、特异性和准确性的影响是通过抽样不同年龄限制的患者来确定的。结果在检测队列中,Light标准对渗出液的敏感性和特异性分别为0.91和0.73。在验证队列中,按年龄组划分,Light标准的敏感性分别为0.99和0.97,特异性分别为0.73和0.68。Light标准及其项目的诊断准确性指标(敏感性、特异性和准确性)随着年龄的增长而下降。结论在解释光的标准时应考虑年龄因素。
{"title":"El efecto de la edad en la precisión de los criterios de Light","authors":"W.-Q. Zheng ,&nbsp;S. Bielsa ,&nbsp;Y. Niu ,&nbsp;J.-X. Wen ,&nbsp;L. Yan ,&nbsp;Z.-D. Hu ,&nbsp;J.M. Porcel","doi":"10.1016/j.rce.2026.502486","DOIUrl":"10.1016/j.rce.2026.502486","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate the effects of age on the sensitivity, specificity, and accuracy of Light's criteria to differentiate exudative from transudative pleural effusion.</div></div><div><h3>Methods</h3><div>A testing cohort from China and a validation cohort from Spain were used for data analysis. The testing cohort included 302 patients (59 transudates and 243 exudates) with undiagnosed pleural effusion. The validation cohort comprised 400 patients (200 transudates and 200 exudates) divided into two groups according to age (200 patients aged 50-65<!--> <!-->years and 200 patients aged 80-95<!--> <!-->years). The effects of age on the sensitivity, specificity, and accuracy of Light's criteria were determined by sampling patients with different age limits.</div></div><div><h3>Results</h3><div>In the testing cohort, the sensitivity and specificity of Light's criteria for exudate were 0.91 and 0.73, respectively. In the validation cohort, the sensitivity was 0.99 and 0.97, and the specificity of Light's criteria for exudate was 0.73 and 0.68, respectively, by age group. The diagnostic accuracy metrics (sensitivity, specificity, and accuracy) of Light's criteria and its items tended to decrease with age.</div></div><div><h3>Conclusion</h3><div>Age should be considered when interpreting the Light's criteria.</div></div>","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":"226 3","pages":"Article 502486"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147429076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Respuesta a: Metodología GRADE en los consensos y guías de práctica clínica para el manejo de la oclusión venosa retiniana 对:GRADE共识方法和视网膜静脉闭塞管理临床实践指南
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-03-01 Epub Date: 2026-02-20 DOI: 10.1016/j.rce.2026.502482
J. Pagán Escribano
{"title":"Respuesta a: Metodología GRADE en los consensos y guías de práctica clínica para el manejo de la oclusión venosa retiniana","authors":"J. Pagán Escribano","doi":"10.1016/j.rce.2026.502482","DOIUrl":"10.1016/j.rce.2026.502482","url":null,"abstract":"","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":"226 3","pages":"Article 502482"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147429081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
La procalcitonina y la región medial de la proadrenomedulina (MR-proADM) podrían ayudar a hacer más segura la hospitalización a domicilio de los pacientes atendidos en urgencias por sospecha de infección 降钙素和前肾上腺素-甲肾上腺素介导区(MR-proADM)可能有助于使因怀疑感染而在急诊室就诊的患者的家庭住院更加安全
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-03-01 Epub Date: 2026-02-16 DOI: 10.1016/j.rce.2026.502472
J. Cabañas Morafraile , L. Serrano Martín , E. de Rafael González , A. Julián-Jiménez , en nombre del grupo URGEN-LABQMIC del CHUT del Instituto de Investigación Sanitaria de Castilla La Mancha (IDISCAM)
{"title":"La procalcitonina y la región medial de la proadrenomedulina (MR-proADM) podrían ayudar a hacer más segura la hospitalización a domicilio de los pacientes atendidos en urgencias por sospecha de infección","authors":"J. Cabañas Morafraile ,&nbsp;L. Serrano Martín ,&nbsp;E. de Rafael González ,&nbsp;A. Julián-Jiménez ,&nbsp;en nombre del grupo URGEN-LABQMIC del CHUT del Instituto de Investigación Sanitaria de Castilla La Mancha (IDISCAM)","doi":"10.1016/j.rce.2026.502472","DOIUrl":"10.1016/j.rce.2026.502472","url":null,"abstract":"","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":"226 3","pages":"Article 502472"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147428020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Insuficiencia cardíaca con fracción de eyección preservada: actualización en estrategias diagnósticas y terapéuticas. Documento de consenso de la SEMI 保留部分射精的心力衰竭:诊断和治疗策略的更新。SEMI协商一致文件
IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-03-01 Epub Date: 2026-02-18 DOI: 10.1016/j.rce.2026.502471
J.M. Fernández Rodríguez , M.B. Alonso-Ortíz , J. Casado Cerrada , D. Chivite Guillen , P. Cubo Romano , R. García Alonso , A. Lorenzo Almorós , J.P. Miramontes-González , L. Soler Rangel , J. Pérez-Silvestre
Heart failure (HF) is associated with high morbidity and mortality. HF with preserved left ventricular ejection fraction (HF-pEF) accounts for up to 50% of all HF cases, being the most common in elderly patients. In addition, these subjects frequently present other comorbidities. For all these reasons, the diagnosis of patients with HF-pEF is complex and requires a careful approach. In addition, there are «secondary» or HF-pEF forms that must also be discarded. The treatment of HF-pEF has evolved very significantly in recent years due to evidence from clinical trials. Until a few years ago, the management was based on the treatment of congestive symptoms with diuretics and comorbidities, to this was added the indication of treatment with SGLT2 inhibitors, after being shown to reduce hospitalizations due to HF, and more recently new evidence of clinical benefit with other drugs such as finerenone, semaglutide or tirzepatide has been published. All this makes it necessary to update the recommendations regarding the management of patients with HF-pEF.
心力衰竭(HF)与高发病率和死亡率相关。保留左心室射血分数(HF- pef)的HF占所有HF病例的50%,在老年患者中最常见。此外,这些受试者经常出现其他合并症。由于所有这些原因,对HF-pEF患者的诊断是复杂的,需要谨慎的方法。此外,还有“次级”或HF-pEF形式也必须丢弃。由于来自临床试验的证据,近年来HF-pEF的治疗有了非常显著的发展。直到几年前,治疗的基础是用利尿剂和合并症治疗充血性症状,在此基础上增加了SGLT2抑制剂治疗的适应症,在被证明可以减少HF的住院治疗后,最近有新的证据表明使用其他药物如芬尼酮、西马鲁肽或替西帕肽有临床益处。所有这些都使得有必要更新有关HF-pEF患者管理的建议。
{"title":"Insuficiencia cardíaca con fracción de eyección preservada: actualización en estrategias diagnósticas y terapéuticas. Documento de consenso de la SEMI","authors":"J.M. Fernández Rodríguez ,&nbsp;M.B. Alonso-Ortíz ,&nbsp;J. Casado Cerrada ,&nbsp;D. Chivite Guillen ,&nbsp;P. Cubo Romano ,&nbsp;R. García Alonso ,&nbsp;A. Lorenzo Almorós ,&nbsp;J.P. Miramontes-González ,&nbsp;L. Soler Rangel ,&nbsp;J. Pérez-Silvestre","doi":"10.1016/j.rce.2026.502471","DOIUrl":"10.1016/j.rce.2026.502471","url":null,"abstract":"<div><div>Heart failure (HF) is associated with high morbidity and mortality. HF with preserved left ventricular ejection fraction (HF-pEF) accounts for up to 50% of all HF cases, being the most common in elderly patients. In addition, these subjects frequently present other comorbidities. For all these reasons, the diagnosis of patients with HF-pEF is complex and requires a careful approach. In addition, there are «secondary» or HF-pEF forms that must also be discarded. The treatment of HF-pEF has evolved very significantly in recent years due to evidence from clinical trials. Until a few years ago, the management was based on the treatment of congestive symptoms with diuretics and comorbidities, to this was added the indication of treatment with SGLT2 inhibitors, after being shown to reduce hospitalizations due to HF, and more recently new evidence of clinical benefit with other drugs such as finerenone, semaglutide or tirzepatide has been published. All this makes it necessary to update the recommendations regarding the management of patients with HF-pEF.</div></div>","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":"226 3","pages":"Article 502471"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147428017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Revista clinica espanola
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