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The value of vaginal wash urea and creatinine concentration for diagnosis of premature rupture of membranes 阴道冲洗尿素和肌酐浓度对胎膜早破的诊断价值
Pub Date : 2022-12-01 DOI: 10.21608/aumj.2022.176893.1029
Mostafa Abu-Elhossen, Mohamed Salah Eldean, Maraey M. Khalil
: Prelabour rupture of fetal membranes (PROM) refers to fetal membrane rupture before the onset of uterine contractions; preterm PROM (PPROM) is the term used when the pregnancy is less than 37 completed weeks of gestation. Purpose: This study aims to assess the accuracy of vaginal fluid urea and creatinine for the diagnosis of premature rupture of membranes and preterm premature rupture of membranes. Patients and Methods: A total of 90 pregnant women were included in the current study, between completed 28 weeks to completed 40 weeks of gestation, divided into two equal groups: 45 pregnant women with PPROM or PROM diagnosed by pooling of fluid in posterior fornix and 45 pregnant women who are attending the outpatient clinic for routine antenatal care, each group had the posterior vaginal fornix irrigated with 5ml saline and aspirated then assessed for urea and creatinine concentration. Results: This study showed that the confirmed PPROM and PROM group had higher levels of vaginal fluid urea and creatinine compared to the control group with a very highly statistically significant difference between the groups. Conclusion: vaginal fluid urea and creatinine determination for the diagnosis of PPROM and PROM is a rapid
:产前胎膜破裂(Prelabour rupture of fetal membrane, PROM)指子宫收缩发生前胎膜破裂;早产早PROM (PPROM)是指妊娠少于37周的情况。目的:本研究旨在评估阴道液尿素和肌酐对胎膜早破和胎膜早破诊断的准确性。患者和方法:本研究共纳入90名妊娠28周至40周的孕妇,分为两组:45名经后穹窿积液诊断为PPROM或PROM的孕妇和45名在门诊进行常规产前护理的孕妇,每组用5ml生理盐水冲洗阴道后穹窿并抽吸,然后评估尿素和肌酐浓度。结果:本研究显示,与对照组相比,确诊PPROM和PROM组阴道液尿素和肌酐水平较高,组间差异具有非常高的统计学意义。结论:阴道液尿素和肌酐测定对PPROM的诊断是快速的
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引用次数: 0
Role of High-resolution Ultrasound Examination in Assessment of Early Undiagnosed Hand Pain 高分辨率超声检查在早期未确诊手痛评估中的作用
Pub Date : 2022-12-01 DOI: 10.21608/aumj.2022.156806.1016
Loay I. Aglan, Nihal Fathi, Sally Hakeem, Salah Maklad, Fatma Elnoby
ABSTRACT
摘要
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引用次数: 0
Validity of Various Severity Scoring System in the Surgical Intensive Care Unit 各种严重程度评分系统在外科重症监护病房的有效性
Pub Date : 2022-12-01 DOI: 10.21608/aumj.2022.159607.1019
Marwa Sayed, A. Abd Elrahman,, Mahmoud M. Hassan, Huda Mahmoud
ABSTRACT
摘要
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引用次数: 0
Serum fetuin-A as a perdictive biomarker of chronic kidney disease 血清胎蛋白a作为慢性肾脏疾病的预测性生物标志物
Pub Date : 2022-12-01 DOI: 10.21608/aumj.2022.147302.1013
Abd allah mahmoud, H. Mahmoud, Atef Abo El-Fadl, M. Kandeel
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引用次数: 0
The Role of Chest Ultrasound in the Detection of Pulmonary Congestion in Hemodialysis patients in Aswan University Hospital 阿斯旺大学医院胸部超声在血液透析患者肺充血检测中的作用
Pub Date : 2022-06-01 DOI: 10.21608/aumj.2022.237810
O. Ali, M. Hafez, Rasha Elnuby Abd Elaziz Abo, Elhasan, Shazly B. Ali
Background; Pulmonary congestion can be existing and frequently symptomless among dialysis cases, but its outcome is unknown. Early detection of pulmonary congestion is an essential aim for the avoidance of congestive heart failure in high-risky cases. Aim and objectives; To assess the role of chest ultrasound in the detection of lung congestion in patients with chronic renal failure under regular hemodialysis. Subjects and methods: A cross-sectional study was conducted at the nephrology department, Aswan university hospital, on 100 patients undergoing regular hemodialysis for at least more than 6 months. Demographic data, echocardiographic, and laboratory investigations were collected. Moreover, chest US was done and IVC diameter was measured predialysis and post- dialysis. Results ; The study included 100 patients; their mean age was 43.66 ±7.6. 52(52%) patients were male,47(47%) were hypertensive and 37(37%) patients were diabetic. There was a substantial reduction in B-Kerley’s lines post dialysis (p<0.001) and there was a substantial change in IVC diameter measurements before and after dialysis (p<0.001). Conclusion ; Chest US is a quick bed-side examination and a non-invasive dependable method for the evaluation of pulmonary congestion in in patients with chronic renal failure under regular hemodialysis.
背景;肺充血可存在,并经常无症状的透析病例,但其结果是未知的。早期发现肺充血是避免充血性心力衰竭在高风险的情况下必不可少的目标。宗旨和目标;目的探讨胸部超声对慢性肾功能衰竭定期血液透析患者肺充血的诊断价值。对象和方法:在阿斯旺大学医院肾内科对100例定期血液透析至少6个月以上的患者进行了横断面研究。收集了人口统计资料、超声心动图和实验室调查。透析前和透析后分别行胸部超声和静脉内径测量。结果;该研究包括100名患者;平均年龄43.66±7.6岁。男性52例(52%),高血压47例(47%),糖尿病37例(37%)。透析后B-Kerley线显著降低(p<0.001),透析前后IVC直径测量有显著变化(p<0.001)。结论;胸部超声(Chest US)是一种快速的床边检查方法,是评估定期血液透析的慢性肾功能衰竭患者肺充血的无创可靠方法。
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引用次数: 0
Preservation of Würinger’s septum during surgeries for women with breast hypertrophy and women with early breast cancer: intra-operative identification of the septum and postoperative outcomes 乳房肥大和早期乳腺癌患者手术中保留<s:1>林格氏隔:术中间隔的识别和术后结果
Pub Date : 2022-06-01 DOI: 10.21608/aumj.2022.237809
Ola Aladdin Muhammad Omar, S. Osman, A. Zidan, O. Abdulraheem
Background Würinger’s septum is a horizontal neurovascular bundle that provides nerve supply to the nipple-areola complex. The septum preservation has been studied in the literature in the context of surgical management of breast hypertrophy to maintain the nipple-areola complex (NAC) sensation. Objective: To evaluate operative experience of preserving the Würinger’s septum. And to evaluate the postoperative patients’ satisfaction Methodology: This study was conducted on 30 women who were scheduled for oncoplastic breast surgery or breast reduction. Preservation of the septum was achieved by careful dissection and gentle manoeuvres. At 3-month postoperative, questionnaire was given to the patients to assess the postoperative satisfaction. Results: This study was conducted on 30 women who underwent breast surgery for breast hypertrophy ( n =20) and early-stage breast cancer ( n =10); six women with breast hypertrophy, and four women without hypertrophy. The postoperative patients’ questionnaire at 3 months postoperatively most women had tendency to accept their breast shapes without braces ( n =28, 93.4%) and with braces ( n =29, 96.7%).Two (6.7%) women were found to have partial NAC loss at 3-month postoperative, none of them were among the cases of women with bilateral breast hypertrophy. Conclusions: Preserving the Würinger’s septum in surgeries for early-stage breast cancer and in breast hypertrophy is non-time consuming surgery and it maintains NAC vascularity and sensation.
背景:林格隔是一个水平的神经血管束,为乳头-乳晕复合体提供神经供应。在乳房肥大的外科治疗中,隔膜保存已被研究,以维持乳头乳晕复合体(NAC)的感觉。目的:探讨保留林格氏隔的手术经验。方法:本研究选取30例拟行乳腺肿瘤整形手术或缩胸手术的女性为研究对象。通过仔细的解剖和温和的操作,隔膜得以保存。术后3个月对患者进行问卷调查,评估术后满意度。结果:本研究纳入了30例因乳房肥大(n =20)和早期乳腺癌(n =10)接受乳房手术的女性;6名女性有乳房肥大,4名女性没有。术后3个月的问卷调查显示,大多数女性在不带牙套(n =28, 93.4%)和带牙套(n =29, 96.7%)的情况下倾向于接受乳房形状。2例(6.7%)患者术后3个月出现部分NAC丢失,均未出现双侧乳房肥大。结论:保留林格隔在早期乳腺癌和乳房肥大手术中是一种省时的手术,能保持NAC的血管通畅和感觉。
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引用次数: 1
IMMUNOHISTOCHEMICAL EXPRESSION OF FORKHEAD BOX (FOX) A1 IN EPITHELIAL OVARIAN CANCER 叉头盒a1在上皮性卵巢癌中的免疫组织化学表达
Pub Date : 2022-06-01 DOI: 10.21608/aumj.2022.237805
Esraa Ali Mohammed Ali Yousef, A. El-Nashar, Shaimaa M. M. Bebars, Rasha M. Mohamed, Samir Said
Background: Ovarian cancer (OC) ranks as the fifth leading cause of malignancy-associated mortality in females. Purpose: This study aims to evaluate the association between A1 immunohistochemical (IHC) FOX expression in epithelial ovarian cancer (EOC) and its relation to their prognosis, as well as its association with other established prognostic indicators like patient's age, tumor laterality, histological subtype, grade and stage, and aims to validate the role of IHC-FOX A1 expression as a prognostic marker in female patients with EOC in Egypt. Patients and Methods: From January 2017 to January 2019 a total of 52 paraffin embedded blocks from patients with EOC were collected. Two serial sections from each tissue block were cut at 4 microns thickness to be used as follows: first section was stained with routine Hematoxylin and Eosin (H&E) to confirm the histologic diagnosis and tumor grade. The second was treated with FOX A1 antibodies to show its expression. Results: High significant relation was detected between advanced patient's age, high tumor grade, advanced stages, tumors with ruptured capsule and ascites and FOX A1 expression regardless tumor laterality. Conclusion: IHC-FOX A1 in EOC is considered a poor prognostic parameter as it is expressed in more than 70% of cases of EOC, significantly with advanced patient's age, high tumor grade, advanced stage, tumors with ruptured capsule and ascites regardless tumor laterality. The results of the present study indicated that FOX A1 could be considered as a poor prognostic marker.
背景:卵巢癌(OC)是女性恶性肿瘤相关死亡的第五大原因。目的:本研究旨在评价上皮性卵巢癌(EOC)中A1免疫组化(IHC) FOX表达与预后的关系,以及与患者年龄、肿瘤侧侧性、组织学亚型、分级、分期等预后指标的关系,验证IHC-FOX A1表达在埃及女性EOC患者中作为预后指标的作用。患者和方法:2017年1月至2019年1月共收集EOC患者石蜡包埋块52例。每个组织块取4微米厚度的连续切片2张,用于:第一张切片常规苏木精和伊红(H&E)染色,以确定组织学诊断和肿瘤分级。第二组用FOX A1抗体处理以显示其表达。结果:晚期患者年龄、肿瘤分级高、肿瘤分期晚期、肿瘤包膜破裂、腹水与FOX A1表达均与肿瘤侧边无关。结论:IHC-FOX A1在70%以上的EOC中表达,与患者年龄大、肿瘤分级高、肿瘤分期晚期、肿瘤囊破裂及腹水无关,被认为是一个较差的预后参数。本研究结果表明FOX A1可被视为预后不良的标志物。
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引用次数: 0
Risk factors of asthma exacerbations in children and its effect on their school absence and performance 儿童哮喘加重的危险因素及其对缺勤和学业表现的影响
Pub Date : 2022-06-01 DOI: 10.21608/aumj.2022.237806
A. Ismail, Enam K Ali, H. Aly, Ahmed A Sedik
Background: Asthma-related school absenteeism affects 59% children with asthma and is linked to lower academic performance, especially among urban minority youth. Objective: To determine risk factors of bronchial asthma and its exacerbation in children attending Aswan University Hospital. Patients and methods: The present study was a prospective cross-sectional study that included 90 known asthmatics patients selected from Pulmonology Clinic and pediatrics department and reception units at Aswan University Hospital through the period from January to June 2020. Results: Patients with asthma exacerbation were older, had longer disease duration and more likely to be males. Likewise, there was statistically significant difference between studied groups regarding family history of asthma. There was statistically significant difference between controlled and uncontrolled asthma as regard Stayed home from school due to respiratory symptoms/asthma, do not taking full part in physical education in school and have respiratory symptoms/asthma associated with physical education or sports. Conclusion: These findings suggest opportunities to improve asthma control. Asthma management at schools is important for pediatric pulmonologists and allergists, primary care providers, and the whole interdisciplinary team working alongside them to provide quality asthma care.
背景:哮喘相关的旷课影响了59%的哮喘儿童,并与学习成绩下降有关,尤其是在城市少数民族青年中。目的:了解阿斯旺大学附属医院儿童支气管哮喘及其加重的危险因素。患者和方法:本研究是一项前瞻性横断面研究,纳入了2020年1月至6月期间从阿斯旺大学医院肺科诊所、儿科和接待单位选择的90例已知哮喘患者。结果:哮喘加重患者年龄较大,病程较长,男性居多。同样,在哮喘家族史方面,研究组之间也存在统计学上的显著差异。在因呼吸道症状/哮喘而待在家里、没有充分参加学校的体育教育以及有与体育或运动有关的呼吸道症状/哮喘方面,控制哮喘和未控制哮喘之间存在统计学差异。结论:这些发现为改善哮喘控制提供了机会。学校的哮喘管理对于儿科肺科医生和过敏症专家、初级保健提供者以及与他们一起工作的整个跨学科团队提供高质量的哮喘护理非常重要。
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引用次数: 0
Hypospadias with Severe Chordee: Single versus Two-Stage Repair: A Comparative Study 尿道下裂伴严重脊索:单期与双期修复:比较研究
Pub Date : 2022-06-01 DOI: 10.21608/aumj.2022.237808
Elshazly Abdelmontlib, Maasoumeh Saleh, M. M. Hussein
Background: A great number of surgical techniques have been developed to adequately correct hypospadias with curvatures greater than 30°. Purpose: to compare the final outcome for repair of hypospadias with severe chordee using single versus two-stage repair and to measure the degree of parent’s satisfaction for both procedures. Materials & Methods: a total of 40 patients with hypospadias associated with severe chordee were divided into 2 groups; 20 patients each repaired with single stage in group I and two stage in group II. Eligible patients included hypospadias with severe chordee and age from 6 months to 12 years. patient were evaluated regarding postoperative complications, cosmetic appearance and parent's satisfaction at 1,3 and 6 months. Results: Patients age ranged from 6 month's to 12 years, fistula was in 6 cases in group I (30%) while group II had no cases of fistula (p=0.039), meatal stenosis was in two cases in each group (p=1). Post-operative complications were 50% versus 10% for single-stage and two-stage repair, respectively. parent satisfaction was excellent in 4 cases in group I (20%) and 7 cases in group II (35%) (p=0.219), very good in 4 cases in both groups (p=1),good in 5 cases in group I (25%) and 9 in group II (45%) (p=0.115) and poor in 7 cases in group I (35%) and 0 cases in group II (p=0.34). There was statistically significant better parents’ satisfaction for the two-stage repair than single stage repair. Conclusion: Two-stage repair was associated with statistically significant less postoperative complications and more parents’ satisfaction than single stage repair.
背景:大量的外科技术已经发展到足以矫正曲率大于30°的尿道下裂。目的:比较重度脊索尿道下裂单段修复与两段修复的最终结果,并测量两种方法的家长满意度。材料与方法:将40例伴有严重脊索的尿道下裂患者分为两组;I组20例,单期修复,II组2期修复。符合条件的患者包括伴有严重脊索的尿道下裂,年龄在6个月至12岁之间。分别于1、3、6个月对患者术后并发症、外观及家长满意度进行评估。结果:患者年龄6个月~ 12岁,组内瘘6例(30%),组内无瘘(p=0.039),组内狭窄2例(p=1)。单期和两期修复的术后并发症分别为50%和10%。家长满意度第一组为优4例(20%),第二组为7例(35%)(p=0.219),两组均为优4例(p=1),第一组为优5例(25%),第二组为优9例(45%)(p=0.115),第二组为差7例(35%),第二组为0例(p=0.34)。两期修复的家长满意度明显高于单期修复。结论:两期修复比单期修复术后并发症少,家长满意度高,具有统计学意义。
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引用次数: 0
Comparative study between Surgical Stripping and Foam Sclerotherapy in management of lower limb varicose Veins 手术剥离与泡沫硬化治疗下肢静脉曲张的比较研究
Pub Date : 2022-06-01 DOI: 10.21608/aumj.2022.237800
M. Kabbash, M. Ismail, A. M. Mohammed, Galal, Ashraf Saad Amin Ahmed
Background: Lower limb Varicose Veins disease among the most prevalent of diseases, it affects all the strata of society, affecting around 20–30% of adults. Objective: Comparing Surgery versus Foam Sclerotherapy in 1ry Lower Limb Varicose Veins treatment. Patients and Methods: This prospective study was conducted on forty patients attended to outpatient clinic of Vascular surgery department Aswan University Hospital with 1ry Lower Limbs varicose veins in one year duration, from January 2018 to January 2019, and admitted to the department. Twenty of them had been Subjected to Surgical Treatment, and the other Twenty patients Subjected to Foam Sclerotherapy Injection. Results: A total of forty patients presented, twenty of them subjected to surgery and the other twenty patients subjected to Foam Sclerotherapy, with net result after one year follow up showed efficacy 85%, and 75% for surgery and Foam Sclerotherapy respectively, and non-significant statistical difference (P value = 0.695 ) to incidence of recurrence of varicosity. Conclusion: Sclerotherapy is promising less invasive, shorter duration intervention, with good short term efficacy, with promising results in comparison to surgery, with need for more data regarding long term efficacy.
背景:下肢静脉曲张病是最流行的疾病之一,它影响社会各阶层,影响约20-30%的成年人。目的:比较手术与泡沫硬化治疗下肢静脉曲张的疗效。患者与方法:本前瞻性研究选取2018年1月至2019年1月在阿斯旺大学医院血管外科门诊就诊的40例下肢静脉曲张患者,时间为1年。其中20例采用手术治疗,其余20例采用泡沫硬化注射治疗。结果:共40例患者,其中手术治疗20例,泡沫硬化治疗20例,1年随访净疗效:手术治疗有效率85%,泡沫硬化治疗有效率75%,静脉曲张复发率差异无统计学意义(P值= 0.695)。结论:硬化疗法具有侵入性小、干预时间短、短期疗效好、较手术治疗效果好等优点,但长期疗效方面需要更多的数据支持。
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引用次数: 0
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Aswan University Medical Journal
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