Pub Date : 2026-10-27DOI: 10.1016/j.ultsonch.2026.108132
Zahoor Ahmed, Muhammad Faisal Manzoor, Umar Farooq, Yibin Zhou, Abderrahmane Aït-Kaddour, Tao Sheng, Chen Chen, Rana Muhammad Aadil, Marwa Ezz El-Din Ibrahim
This study investigates the interactive mechanisms between ultrasound-treated red rice bran dietary fiber (URBDF) and anthocyanins to improve their physicochemical stability, bioaccessibility, and structural integrity via ultrasound treatment (300 W, 50 °C, liquid-to-solid ratio 30:1, 40 min). Ultrasound treatment increased the fiber’s porosity and specific surface area, which significantly enhanced its adsorption capacity toward anthocyanins (42.54 ± 0.87 mg/g). Optimal adsorption conditions (pH 5, 37 °C, 95 min, anthocyanin concentration 3 mg/mL) yielded stable URBDF + RBA complexes with improved functional performance, as proved by spectroscopic and microscopic analyses. The hydrogen bonding and hydrophobic interactions were the dominant non-covalent forces mediating URBDF + RBA association and interactions effectively, which inhibited anthocyanin degradation and crystallization, resulting in markedly enhanced thermal and environmental stability. The anthocyanin retention up to 94.3 % under stress conditions induced structural modification of ultrasound treatment, reduced the particle size and increased the surface roughness and hydrophilicity of the fiber. The results on microstructure, rheological properties, water-holding, oil-binding, swelling capacities, and simulated gastrointestinal digestion demonstrated that URBDF binding substantially improved antioxidant activity and bioaccessibility as compared to untreated samples. Cell experiments showed that RBDF, URBDF, RBDF + anthocyanin and URBDF + anthocyanin had different degrees of proliferative effects on L-02 and RAW264.7. This work provides mechanistic insight into ultrasound-assisted red rice bran by-products and dietary fiber modification as a sustainable strategy for stabilizing anthocyanins. The findings establish a foundation for developing novel fiber anthocyanin complexes with improved stability and functionality for applications in natural systems, functional foods and nutraceuticals.
{"title":"Ultrasound-assisted formation of red rice bran fiber-anthocyanin complexes: Improved bioaccessibility and color stability","authors":"Zahoor Ahmed, Muhammad Faisal Manzoor, Umar Farooq, Yibin Zhou, Abderrahmane Aït-Kaddour, Tao Sheng, Chen Chen, Rana Muhammad Aadil, Marwa Ezz El-Din Ibrahim","doi":"10.1016/j.ultsonch.2026.108132","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2026.108132","url":null,"abstract":"This study investigates the interactive mechanisms between ultrasound-treated red rice bran dietary fiber (URBDF) and anthocyanins to improve their physicochemical stability, bioaccessibility, and structural integrity via ultrasound treatment (300 W, 50 °C, liquid-to-solid ratio 30:1, 40 min). Ultrasound treatment increased the fiber’s porosity and specific surface area, which significantly enhanced its adsorption capacity toward anthocyanins (42.54 ± 0.87 mg/g). Optimal adsorption conditions (pH 5, 37 °C, 95 min, anthocyanin concentration 3 mg/mL) yielded stable URBDF + RBA complexes with improved functional performance, as proved by spectroscopic and microscopic analyses. The hydrogen bonding and hydrophobic interactions were the dominant non-covalent forces mediating URBDF + RBA association and interactions effectively, which inhibited anthocyanin degradation and crystallization, resulting in markedly enhanced thermal and environmental stability. The anthocyanin retention up to 94.3 % under stress conditions induced structural modification of ultrasound treatment, reduced the particle size and increased the surface roughness and hydrophilicity of the fiber. The results on microstructure, rheological properties, water-holding, oil-binding, swelling capacities, and simulated gastrointestinal digestion demonstrated that URBDF binding substantially improved antioxidant activity and bioaccessibility as compared to untreated samples. Cell experiments showed that RBDF, URBDF, RBDF + anthocyanin and URBDF + anthocyanin had different degrees of proliferative effects on L-02 and RAW264.7. This work provides mechanistic insight into ultrasound-assisted red rice bran by-products and dietary fiber modification as a sustainable strategy for stabilizing anthocyanins. The findings establish a foundation for developing novel fiber anthocyanin complexes with improved stability and functionality for applications in natural systems, functional foods and nutraceuticals.","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"14 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2026-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149274925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-10-26DOI: 10.1016/j.ultsonch.2026.108138
Ming Xu, Haijun Zhang, Martin Rudolph
Dodecylamine (DDA), a cationic surfactant widely used in quartz flotation, can promote microbubble formation during ultrasonication; however, these ultrasonication-generated (UG) microbubbles may rapidly dissolve once the ultrasonic field is removed. This study hypothesizes that combining DDA with air oversaturation can markedly suppress post-ultrasonication microbubble dissolution and thereby enhance quartz flotation. UG bulk and surface microbubbles were characterized using dissolved-air measurements and optical imaging, while surface tension and contact angle measurements were used to elucidate the role of DDA. Flotation performance was evaluated using bubble pick-up and micro-flotation tests. DDA markedly increases the population of persistent UG microbubbles under air-oversaturated conditions, whereas no clear DDA-induced increase is observed under non-oversaturated conditions. This behavior is consistent with the coupled effects of air oversaturation and the DDA-induced reduction in gas–liquid interfacial tension, which together enhance the diffusive stability of microbubbles. The unexpectedly rapid decrease in bubble contact angle following bubble-solid contact in DDA solution suggests possible interfacial redistribution of DDA from the solid surface to the gas–liquid interface, which may accelerate the local reduction in gas–liquid interfacial tension. The resulting larger population of persistent microbubbles markedly enhances quartz-particle attachment to carrier bubbles and improves flotation recovery, highlighting the coupled roles of air oversaturation and surfactant adsorption in ultrasound-assisted flotation
{"title":"Dodecylamine-promoted persistence of ultrasonication-generated microbubbles and its implications for quartz flotation","authors":"Ming Xu, Haijun Zhang, Martin Rudolph","doi":"10.1016/j.ultsonch.2026.108138","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2026.108138","url":null,"abstract":"Dodecylamine (DDA), a cationic surfactant widely used in quartz flotation, can promote microbubble formation during ultrasonication; however, these ultrasonication-generated (<ce:italic>UG</ce:italic>) microbubbles may rapidly dissolve once the ultrasonic field is removed. This study hypothesizes that combining DDA with air oversaturation can markedly suppress post-ultrasonication microbubble dissolution and thereby enhance quartz flotation. <ce:italic>UG</ce:italic> bulk and surface microbubbles were characterized using dissolved-air measurements and optical imaging, while surface tension and contact angle measurements were used to elucidate the role of DDA. Flotation performance was evaluated using bubble pick-up and micro-flotation tests. DDA markedly increases the population of persistent <ce:italic>UG</ce:italic> microbubbles under air-oversaturated conditions, whereas no clear DDA-induced increase is observed under non-oversaturated conditions. This behavior is consistent with the coupled effects of air oversaturation and the DDA-induced reduction in gas–liquid interfacial tension, which together enhance the diffusive stability of microbubbles. The unexpectedly rapid decrease in bubble contact angle following bubble-solid contact in DDA solution suggests possible interfacial redistribution of DDA from the solid surface to the gas–liquid interface, which may accelerate the local reduction in gas–liquid interfacial tension. The resulting larger population of persistent microbubbles markedly enhances quartz-particle attachment to carrier bubbles and improves flotation recovery, highlighting the coupled roles of air oversaturation and surfactant adsorption in ultrasound-assisted flotation","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"14 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2026-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149274639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This article successfully synthesized CuO/CuBi2O4 composite material through a two-step method. The material, as a sonocatalyst, can effectively degrade bisphenol A (BPA) in water when activated by ultrasound, and its synergistic effect with peroxymonosulfate (PMS) can further enhance the degradation effect. CuO/CuBi2O4 composite with a 60% composite ratio (CC-60) exhibited the optimal sonocatalytic performance, and the US/CC-60/PMS system with PMS added exhibited more outstanding sonocatalytic activity than the original system. In optimal experimental conditions, the removal rate of BPA was 98.48 ± 0.39%. Trapping experiments and in-situ X-ray photoelectron spectroscopy results confirmed the formation of an S-scheme heterojunction between CuO and CuBi2O4. This heterojunction effectively promoted electron-hole pair separation, significantly enhanced the ultrasonic catalytic performance of CuBi2O4. Furthermore, within the US/CC-60/PMS system, BPA was efficiently degraded with a rate constant of 0.219 min−1, which substantially exceeded those of US/PMS (0.008 min−1) and US/CC-60 (0.019 min−1) system. The results demonstrated that the synergistic interaction among the system components significantly enhanced sonocatalytic activity. CC-60 has shown excellent stability and reusability in the application process, and still maintains a high BPA removal rate in actual water. It also has a wide range of pH and anion tolerance, demonstrating excellent development potential. This study not only developed a unique sonocatalyst for decomposing aquatic pollutants but also provided new insights for successfully constructing novel sonocatalytic degradation systems.
{"title":"Construction of CuO/CuBi2O4 S‑scheme heterojunctions with enhanced sonocatalytic performance combined with peroxymonosulfate for the removal of bisphenol A","authors":"Yang-Cheng Liu, Hai-Tao Qiu, Xue-Yun Dong, Mao-Qi Yang, Xin Wang, Zheng Xiang, Ling-Ling Jiang","doi":"10.1016/j.ultsonch.2026.108131","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2026.108131","url":null,"abstract":"This article successfully synthesized CuO/CuBi<ce:inf loc=\"post\">2</ce:inf>O<ce:inf loc=\"post\">4</ce:inf> composite material through a two-step method. The material, as a sonocatalyst, can effectively degrade bisphenol A (BPA) in water when activated by ultrasound, and its synergistic effect with peroxymonosulfate (PMS) can further enhance the degradation effect. CuO/CuBi<ce:inf loc=\"post\">2</ce:inf>O<ce:inf loc=\"post\">4</ce:inf> composite with a 60% composite ratio (CC-60) exhibited the optimal sonocatalytic performance, and the US/CC-60/PMS system with PMS added exhibited more outstanding sonocatalytic activity than the original system. In optimal experimental conditions, the removal rate of BPA was 98.48 ± 0.39%. Trapping experiments and in-situ X-ray photoelectron spectroscopy results confirmed the formation of an S-scheme heterojunction between CuO and CuBi<ce:inf loc=\"post\">2</ce:inf>O<ce:inf loc=\"post\">4</ce:inf>. This heterojunction effectively promoted electron-hole pair separation, significantly enhanced the ultrasonic catalytic performance of CuBi<ce:inf loc=\"post\">2</ce:inf>O<ce:inf loc=\"post\">4</ce:inf>. Furthermore, within the US/CC-60/PMS system, BPA was efficiently degraded with a rate constant of 0.219 min<ce:sup loc=\"post\">−1</ce:sup>, which substantially exceeded those of US/PMS (0.008 min<ce:sup loc=\"post\">−1</ce:sup>) and US/CC-60 (0.019 min<ce:sup loc=\"post\">−1</ce:sup>) system. The results demonstrated that the synergistic interaction among the system components significantly enhanced sonocatalytic activity. CC-60 has shown excellent stability and reusability in the application process, and still maintains a high BPA removal rate in actual water. It also has a wide range of pH and anion tolerance, demonstrating excellent development potential. This study not only developed a unique sonocatalyst for decomposing aquatic pollutants but also provided new insights for successfully constructing novel sonocatalytic degradation systems.","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"64 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2026-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149274709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-10-22DOI: 10.1016/j.ultsonch.2026.108130
Weiting Wang, Joydip Mondal, Yongbin Han, Yang Tao, Yue Wu
{"title":"Structural modification of soybean β-conglycinin by low/medium frequency ultrasound: impacts on oil-water interface adsorption and stability","authors":"Weiting Wang, Joydip Mondal, Yongbin Han, Yang Tao, Yue Wu","doi":"10.1016/j.ultsonch.2026.108130","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2026.108130","url":null,"abstract":"","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"76 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149232785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-10-19DOI: 10.1016/j.ultsonch.2026.108125
Zhenxiang Ji, Zhetao Shangguan, Jie Jin, Ruoyan Yang, Wei Li, Tianyi Yan, Dingjie Suo
{"title":"Numerical investigation of cavitation and translational dynamics of 3D bubble clusters in viscoelastic tissues","authors":"Zhenxiang Ji, Zhetao Shangguan, Jie Jin, Ruoyan Yang, Wei Li, Tianyi Yan, Dingjie Suo","doi":"10.1016/j.ultsonch.2026.108125","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2026.108125","url":null,"abstract":"","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"2 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149232490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Viscous damping and acoustic radiation pressure challenge the ultrasonic atomization of high-viscosity and high-surface-tension fluids. To address this issue and reveal the underlying mechanisms, a rotational ultrasonic atomization platform was developed. The effects of ultrasonic power, liquid viscosity, horn geometry, rotation speed, and initial momentum on atomization behavior were investigated using high-speed imaging. For low-viscosity liquids, increasing ultrasonic power elevated the Weber number, widened the spray angle from 63 degrees to 142 degrees, and shortened the atomization incubation period from 10.86 s to 8.15 s. For high-viscosity liquids, viscous damping suppressed the capillary wave pathway, making cavitation the dominant mechanism. Driven by the secondary Bjerknes force, cavitation bubbles bridged into branched, neural-network-like clusters. Their collective collapse overcame the viscous dissipation barrier, providing experimental validation for Boguslavskii’s hypothesis. A critical rotation threshold of 60 revolutions per minute was identified. Below this threshold, acoustic pinning confined the liquid on the horn end-face; above it, centrifugal force forcibly thinned the liquid film, triggering atomization. Furthermore, horn geometry determined the atomization onset location, while increased initial momentum accelerated initiation. Experiments on Sn-58Bi melt verified that coupling optimized horn geometry with a centrifugal force field effectively overcomes the surface energy barrier. Based on these findings, a six-stage atomization model is proposed. The capillary wave mechanism primarily achieves initial film thinning by stripping large droplets, while cavitation dominates fine fragmentation. This work systematically investigates the atomization mechanism of high-resistance fluids and demonstrates the fabrication of metal powders via rotational ultrasonic atomization.
{"title":"Regulation of ultrasonic atomization behavior and preparation of low-melting-point alloy powders","authors":"Xiaofeng Yang, Haodi Li, Dingying Ren, Hao Lan, Xiaoqiang Hu, Qian Wang, Peng Yu","doi":"10.1016/j.ultsonch.2026.108082","DOIUrl":"10.1016/j.ultsonch.2026.108082","url":null,"abstract":"<div><div>Viscous damping and acoustic radiation pressure challenge the ultrasonic atomization of high-viscosity and high-surface-tension fluids. To address this issue and reveal the underlying mechanisms, a rotational ultrasonic atomization platform was developed. The effects of ultrasonic power, liquid viscosity, horn geometry, rotation speed, and initial momentum on atomization behavior were investigated using high-speed imaging. For low-viscosity liquids, increasing ultrasonic power elevated the Weber number, widened the spray angle from 63 degrees to 142 degrees, and shortened the atomization incubation period from 10.86 s to 8.15 s. For high-viscosity liquids, viscous damping suppressed the capillary wave pathway, making cavitation the dominant mechanism. Driven by the secondary Bjerknes force, cavitation bubbles bridged into branched, neural-network-like clusters. Their collective collapse overcame the viscous dissipation barrier, providing experimental validation for Boguslavskii’s hypothesis. A critical rotation threshold of 60 revolutions per minute was identified. Below this threshold, acoustic pinning confined the liquid on the horn end-face; above it, centrifugal force forcibly thinned the liquid film, triggering atomization. Furthermore, horn geometry determined the atomization onset location, while increased initial momentum accelerated initiation. Experiments on Sn-58Bi melt verified that coupling optimized horn geometry with a centrifugal force field effectively overcomes the surface energy barrier. Based on these findings, a six-stage atomization model is proposed. The capillary wave mechanism primarily achieves initial film thinning by stripping large droplets, while cavitation dominates fine fragmentation. This work systematically investigates the atomization mechanism of high-resistance fluids and demonstrates the fabrication of metal powders via rotational ultrasonic atomization.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"133 ","pages":"Article 108082"},"PeriodicalIF":10.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149049957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-10-01Epub Date: 2026-09-23DOI: 10.1016/j.ultsonch.2026.108074
Yi Zhao, Xiaoyu Sun, Mu Li, Mangen Li, Xianping Luo, Zhihong Zheng, Chao Liu, Yongwen Zhang, Haiyan Liu, Chuan He, Zhiyuan Ma
To overcome the issues of low recovery and non-uniform mining caused by gravity-driven vertical preferential flow during the in-situ leaching (ISL) of ion-adsorption type rare earth ores (IREOs), this study systematically investigated the enhancement laws of ultrasound on lateral seepage and mass transfer. This study constructed an ultrasonic coupling lateral column leaching system to simulate the in-situ leaching process. The effects of ultrasonic parameters (probe position, power and mode) on the lateral seepage rate and leaching efficiency were investigated. Influence of thermal effect and ultrasonic effect on leaching was distinguished. The results indicate that applying ultrasound in the middle position of the ore body achieves the higher leaching efficiency and lateral seepage rate compared to other positions. Under an optimized pulsed mode (360 W, 5 min on/5 min off, 5 h), the leaching efficiency of rare earth elements (REEs) reached 94.4 %, representing a 9 % increase over the temperature control and a 22 % increase over conventional leaching. Concurrently, the average lateral seepage rate increased by 0.317 mL/min, and the leaching duration was shortened by 37.8 %. Although the leaching efficiency of the 5/15 mode is slightly lower, its superior energy efficiency is more attractive in industry. Characterization results revealed that ultrasound induced particle benign refinement, surface erosion, and pore development, increasing the specific surface area by 42 %. Kinetic analysis confirmed that ultrasound shifted the rate-limiting step from external diffusion control to chemical reaction control, effectively eliminating mass transfer resistance. This enhancement is attributed to the synergistic effects of mechanical vibration and cavitation, which reconstruct the pore structure and improve the reaction interface. This work provides insights into overcoming physical seepage barriers to achieve efficient and green mining of IREOs.
{"title":"Enhancement of lateral seepage and mass transfer in ionic rare earth ores by ultrasonic stimulation during in-situ leaching","authors":"Yi Zhao, Xiaoyu Sun, Mu Li, Mangen Li, Xianping Luo, Zhihong Zheng, Chao Liu, Yongwen Zhang, Haiyan Liu, Chuan He, Zhiyuan Ma","doi":"10.1016/j.ultsonch.2026.108074","DOIUrl":"10.1016/j.ultsonch.2026.108074","url":null,"abstract":"<div><div>To overcome the issues of low recovery and non-uniform mining caused by gravity-driven vertical preferential flow during the in-situ leaching (ISL) of ion-adsorption type rare earth ores (IREOs), this study systematically investigated the enhancement laws of ultrasound on lateral seepage and mass transfer. This study constructed an ultrasonic coupling lateral column leaching system to simulate the in-situ leaching process. The effects of ultrasonic parameters (probe position, power and mode) on the lateral seepage rate and leaching efficiency were investigated. Influence of thermal effect and ultrasonic effect on leaching was distinguished. The results indicate that applying ultrasound in the middle position of the ore body achieves the higher leaching efficiency and lateral seepage rate compared to other positions. Under an optimized pulsed mode (360 W, 5 min on/5 min off, 5 h), the leaching efficiency of rare earth elements (REEs) reached 94.4 %, representing a 9 % increase over the temperature control and a 22 % increase over conventional leaching. Concurrently, the average lateral seepage rate increased by 0.317 mL/min, and the leaching duration was shortened by 37.8 %. Although the leaching efficiency of the 5/15 mode is slightly lower, its superior energy efficiency is more attractive in industry. Characterization results revealed that ultrasound induced particle benign refinement, surface erosion, and pore development, increasing the specific surface area by 42 %. Kinetic analysis confirmed that ultrasound shifted the rate-limiting step from external diffusion control to chemical reaction control, effectively eliminating mass transfer resistance. This enhancement is attributed to the synergistic effects of mechanical vibration and cavitation, which reconstruct the pore structure and improve the reaction interface. This work provides insights into overcoming physical seepage barriers to achieve efficient and green mining of IREOs.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"133 ","pages":"Article 108074"},"PeriodicalIF":10.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149073089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-10-01Epub Date: 2026-09-24DOI: 10.1016/j.ultsonch.2026.108076
Na Guo, Le Yang, Xi-Bing Cao, Xiao-Qiao Zhai, Guo-Qiang Fan
The traditional methods for extraction and separation of polysaccharides usually have the shortcomings of long processing time and complex operation procedures. The objective of this study was to develop an efficient and integrated strategy for synergistic extraction and separation of polysaccharides from Paulownia fortunei flowers by ultrasound-assisted deep eutectic solvents extraction (UADES) combined with gradient ethanol precipitation (GEP). The extraction conditions were successively optimized using single-factor experiments and response surface methodology. Under the optimal conditions, the maximum extraction yield of P. fortunei flowers polysaccharides (PFP) reached 5.91 ± 0.29%, which was 3.05-fold higher than that of conventional hot water extraction (CHWE). Analysis of tissue morphology, and molecular dynamics simulations of DES and PFP both indicated that this extraction method was superior to CHWE. Meanwhile, PFP can be fractionated and purified through GEP. Three polysaccharide fractions, namely PFP-40, PFP-60, and PFP-80, were obtained at the final ethanol precipitation concentrations of 40%, 60%, and 80% (v/v), respectively. All fractions also showed differences in structural characterizations. In vitro activity assays demonstrated that all polysaccharide fractions exhibited antioxidant activity and tyrosinase inhibitory activity, and PFP-80 showed the strongest bioactivity. Further mechanistic studies indicated that the inhibition of tyrosinase by PFP-80 was reversible and mixed-type, their interaction occurred through a static quenching mechanism. This study introduced a strategy for DES recycling post-GEP for polysaccharide extraction, and the PFP showed potential for applications in the food and pharmaceutical industries.
{"title":"Ultrasound-assisted deep eutectic solvent extraction combined with gradient ethanol precipitation of polysaccharides from Paulownia fortunei flowers: Process optimization, physicochemical characterization, bioactivity evaluation","authors":"Na Guo, Le Yang, Xi-Bing Cao, Xiao-Qiao Zhai, Guo-Qiang Fan","doi":"10.1016/j.ultsonch.2026.108076","DOIUrl":"10.1016/j.ultsonch.2026.108076","url":null,"abstract":"<div><div>The traditional methods for extraction and separation of polysaccharides usually have the shortcomings of long processing time and complex operation procedures. The objective of this study was to develop an efficient and integrated strategy for synergistic extraction and separation of polysaccharides from <em>Paulownia fortunei</em> flowers by ultrasound-assisted deep eutectic solvents extraction (UADES) combined with gradient ethanol precipitation (GEP). The extraction conditions were successively optimized using single-factor experiments and response surface methodology. Under the optimal conditions, the maximum extraction yield of <em>P. fortunei</em> flowers polysaccharides (PFP) reached 5.91 ± 0.29%, which was 3.05-fold higher than that of conventional hot water extraction (CHWE). Analysis of tissue morphology, and molecular dynamics simulations of DES and PFP both indicated that this extraction method was superior to CHWE. Meanwhile, PFP can be fractionated and purified through GEP. Three polysaccharide fractions, namely PFP-40, PFP-60, and PFP-80, were obtained at the final ethanol precipitation concentrations of 40%, 60%, and 80% (v/v), respectively. All fractions also showed differences in structural characterizations. <em>In vitro</em> activity assays demonstrated that all polysaccharide fractions exhibited antioxidant activity and tyrosinase inhibitory activity, and PFP-80 showed the strongest bioactivity. Further mechanistic studies indicated that the inhibition of tyrosinase by PFP-80 was reversible and mixed-type, their interaction occurred through a static quenching mechanism. This study introduced a strategy for DES recycling post-GEP for polysaccharide extraction, and the PFP showed potential for applications in the food and pharmaceutical industries.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"133 ","pages":"Article 108076"},"PeriodicalIF":10.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149049546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：