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An Ill-bred Culture of Experimentation: Malaria Therapy and Race in the United States Public Health Service Laboratory at the South Carolina State Hospital, 1932-1952. 缺乏教养的实验文化:1932-1952年南卡罗来纳州医院美国公共卫生服务实验室的疟疾治疗和种族。
IF 0.9 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-13 DOI: 10.1093/jhmas/jrad063
Bradford Charles Pelletier

While most are aware of the Tuskegee syphilis experiments in which African American syphilis patients went untreated, less is known about experiments with malaria fever therapy conducted upon syphilis patients during the same period by the Unites States Public Health Service at the Williams Laboratory on the grounds of the South Carolina State Hospital (SCSH) in Columbia, SC. Over a twenty-year period, physicians maintained patients as malaria reservoirs for patient-to-patient inoculation and subjected patients to extreme fevers and thousands upon thousands of insect bites as part of a program in which one disease was tested as therapy for another. Using extant administrative files, medical journals from the period, and a database created from SCSH annual reports, this paper considers the ethics of malaria fever therapy experiments while exposing the conditions under which patients suffered the intersecting oppressions of race, class, and mental illness. It illuminates the prevalent scientific racism of the period that enabled pseudo-medical assumptions about African Americans' perceived penchant for poverty, deviant sex, and pain tolerance, which combined to enable a culture of experimentation that influenced events at Stateville Penitentiary and continued long after penicillin became widely available.

虽然大多数人都知道塔斯基吉梅毒实验,其中非洲裔美国人的梅毒患者没有得到治疗,但鲜为人知的是,在同一时期,美国公共卫生服务部门在南卡罗来纳州哥伦比亚市南卡罗来纳州立医院(SCSH)的威廉姆斯实验室对梅毒患者进行了疟疾热治疗的实验。医生们把病人当作疟疾的宿主,让他们在病人之间接种疟疾,让病人忍受极度的发烧和成千上万的昆虫叮咬,这是一个项目的一部分,在这个项目中,一种疾病被测试为另一种疾病的治疗方法。本文利用现存的行政文件、该时期的医学期刊和SCSH年度报告创建的数据库,在揭示患者遭受种族、阶级和精神疾病交叉压迫的条件下,考虑疟疾治疗实验的伦理。它阐明了那个时期普遍存在的科学种族主义,这种种族主义使非裔美国人对贫困、不正常的性行为和疼痛耐受性的感知倾向产生了伪医学假设,这些假设结合在一起,形成了一种实验文化,影响了Stateville监狱的事件,并在青霉素广泛使用后长期持续下去。
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引用次数: 0
Notes from the Front: The Casebook of a Renaissance Hospital Surgeon. 前面的笔记:文艺复兴医院外科医生的案例手册。
IF 0.9 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-13 DOI: 10.1093/jhmas/jrad064
Sharon Strocchia

This essay uses the unpublished casebook kept by the Tuscan surgeon Giovanbattista Nardi to examine the provision of urgent medical care in sixteenth-century Italian hospitals. Most major hospitals on the peninsula maintained separate therapeutic spaces known as medicherie for this purpose. Written in the 1580s while Nardi worked as a staff surgeon at a Florentine civic hospital, this rare surgical casebook provides insight into the types of institutional resources devoted to acute medical problems; the clientele seeking immediate assistance and the situations that brought them there; the treatments used to achieve short-term "cures"; and the clinical experiences of hospital surgeons who served as frontline healers. A close analysis of the seventy-nine cases recorded sheds new light on everyday surgical treatments for conditions ranging from serious head injuries requiring trephination to syphilitic lesions and genital trauma. Casebook entries also reveal Nardi's deep engagement with the composition and use of topical remedies as both practitioner and experimenter. Intended as a memory aid for future reference, the casebook shows material traces of the author's shifting occupational identity as he matured from hospital surgeon to university-trained physician. Viewed through multiple lenses, this richly layered source expands our understanding of both the practice and profession of early modern surgery.

本文使用托斯卡纳外科医生Giovanbattista Nardi保存的未出版的案例书来研究16世纪意大利医院提供紧急医疗服务的情况。半岛上的大多数主要医院都为此保留了被称为medicerie的独立治疗空间。这本罕见的外科案例书写于1580年代,当时纳尔迪在佛罗伦萨一家市政医院担任外科医生,深入了解了专门用于急性医疗问题的机构资源类型;寻求立即援助的客户以及将他们带到那里的情况;用于实现短期“治愈”的治疗方法;以及作为一线治疗师的医院外科医生的临床经验。对记录的79例病例的仔细分析为日常手术治疗提供了新的线索,从需要钻孔的严重头部损伤到梅毒病变和生殖器创伤。案例书条目还揭示了Nardi作为从业者和实验者对局部药物的组成和使用的深刻参与。这本案例书旨在为未来的参考提供记忆帮助,展示了作者从医院外科医生成长为大学医生时职业身份转变的物质痕迹。从多个角度来看,这个层次丰富的来源扩展了我们对早期现代外科实践和专业的理解。
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引用次数: 0
What Evidence for a Cholera Vaccine? Jaime Ferrán's Submissions to the Prix Bréant. 霍乱疫苗的证据是什么?Jaime Ferrán向布雷昂大奖赛提交的参赛作品。
IF 0.9 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-13 DOI: 10.1093/jhmas/jrad062
Clara Uzcanga, David Teira

This article analyses how the French Academy of Sciences assessed Jaime Ferrán's cholera vaccine submitted for the Prix Bréant in the 1880s. Ferrán, a Spanish independent physician, discovered the treatment in 1884 and tried it on thousands of patients during the cholera outbreak in Valencia the following year. His evaluation sparked a controversy in Spain and abroad on the vaccine's efficacy. The Bréant jury did not see any evidence for it in Ferrán's submission, a decision usually interpreted in terms of French scientific nationalism (or simple chauvinism): an outsider from the scientific periphery could not be awarded the Bréant. Drawing on the archival records of the award, we suggest that Ferrán failed instead to provide data that the Academy could consider unbiased, according to the contemporary standards for data presentation. We will illustrate these standards at work in the assessment of another submission from Spain, by Philip Hauser, who received the Bréant for the thoroughness of his statistical endeavour.

本文分析了法国科学院如何评估杰米·费兰在19世纪80年代提交给布雷昂大奖赛的霍乱疫苗。西班牙独立医生Ferrán于1884年发现了这种疗法,并在次年巴伦西亚霍乱爆发期间对数千名患者进行了试验。他的评价在西班牙国内外引发了对疫苗效力的争议。Bréant陪审团在Ferrán的意见书中没有看到任何证据,这一决定通常被解释为法国的科学民族主义(或简单的沙文主义):来自科学外围的局外人不能被授予Brént奖。根据该奖项的档案记录,我们认为Ferrán未能根据当代数据呈现标准提供学院认为公正的数据。我们将在评估西班牙菲利普·豪泽提交的另一份材料时说明这些标准的作用,他因其统计工作的彻底性而获得Bréant奖。
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引用次数: 0
Town Planning, Housing, and the Politics of Sanitation and Public Health in the Gold Coast (Colonial Ghana), c. 1880 - 1950. 《黄金海岸(殖民地加纳)的城镇规划、住房和卫生与公共卫生政治》,约1880-1950年。
IF 0.9 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-13 DOI: 10.1093/jhmas/jrad057
Akwasi Kwarteng Amoako-Gyampah

Colonial officials remarked disparagingly about the nature of houses and what they presented as congested layouts in Gold Coast communities. Subsequently, drawing on nineteenth-century epidemiological theory that connected diseases and poor health to defective housing and congested settlements, the colonial administration introduced measures to redesign and reorder Gold Coast communities. This article examines the connection between colonial town planning and housing measures and the politics of sanitation and public health in the Gold Coast. It argues that the colonial state's imposition of imported British town planning measures, building techniques, and housing styles in the Gold Coast and their aspiration to compel Gold Coast people to build and pattern their communities along so-called sanitary lines could not be fully realised. Thus, the extent to which colonial town planning and the accompanying transformations in African building styles improved sanitation and consequently, public health, is difficult to determine. Nonetheless, this study reveals that the local population's holistic approaches to spatial designing and planning of their communities and their building styles were somewhat altered by the colonial imposition of eurocentric town planning policies and building styles.

殖民地官员轻蔑地评论了房屋的性质,以及他们所说的黄金海岸社区拥挤的布局。随后,殖民政府借鉴了19世纪的流行病学理论,将疾病和健康状况不佳与有缺陷的住房和拥挤的定居点联系起来,采取措施重新设计和重新安排黄金海岸社区。本文探讨了殖民地城市规划和住房措施与黄金海岸卫生和公共卫生政治之间的联系。它认为,殖民国家在黄金海岸实施进口的英国城镇规划措施、建筑技术和住房风格,以及他们迫使黄金海岸人民沿着所谓的卫生线建设和规划社区的愿望,都无法完全实现。因此,殖民地城市规划和随之而来的非洲建筑风格的转变在多大程度上改善了卫生条件,从而改善了公共卫生,这一点很难确定。尽管如此,这项研究表明,殖民地强加的以欧洲为中心的城市规划政策和建筑风格在一定程度上改变了当地居民对社区及其建筑风格的空间设计和规划的整体方法。
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引用次数: 0
Out of Breath: Toward a New Origin Story of Public Health. 喘不过气来:迈向公共卫生的新起源故事》。
IF 0.9 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-09-23 DOI: 10.1093/jhmas/jrae013
Jim Downs

Problems caused by overcrowding and the simple need to breathe represent one of the major consequences of medical racism. With few exceptions, histories of epidemics, disease prevention, and sanitation often focus on municipal reform efforts to clean up gritty urban centers from London to Paris to New York. This article traces how concerns about ventilation emerged during the transatlantic slave trade and continued to be a problem for Black people throughout the eighteenth, nineteenth and twentieth centuries. The article emphasizes that Black people were not just the victims of medical racism but initiated many crusades in the United States to promote better ventilation throughout the twentieth century. This article highlights the work of Black reformers, doctors, and thinkers who fought to create healthy living conditions for Black people.

过度拥挤和简单的呼吸需求造成的问题是医学种族主义的主要后果之一。除少数例外,有关流行病、疾病预防和环境卫生的历史通常侧重于市政改革,以清理从伦敦、巴黎到纽约等城市中心的脏乱差。本文追溯了对通风问题的关注是如何在跨大西洋奴隶贸易期间出现并在整个十八、十九和二十世纪继续成为黑人的一个问题的。文章强调,黑人不仅仅是医学种族主义的受害者,在整个二十世纪,他们还在美国发起了许多促进改善通风的运动。本文重点介绍了为黑人创造健康生活条件而奋斗的黑人改革家、医生和思想家的工作。
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引用次数: 0
Re-Writing Pandemic Histories: Introduction. 重写大流行病的历史:导言。
IF 0.9 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-09-23 DOI: 10.1093/jhmas/jrae005
Jacob Steere-Williams, Claire Edington
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引用次数: 0
"Pandemics know no borders," but Responses to Pandemics Do: Global Health, COVID-19, and Latin America. "大流行病无国界,但应对大流行病有国界:全球健康、COVID-19 和拉丁美洲。
IF 0.9 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-09-23 DOI: 10.1093/jhmas/jrae010
Marcos Cueto

This article focuses on Brazil and Peru, the Latin American epicenter of the coronavirus pandemic during 2020 and 2021. The pandemic magnified the legacy of years of neoliberal policies, corruption and racism in these countries, the limitations of their poverty-reduction programs, the fragility of their democratic systems, and the insufficient political regard for public health and basic sanitation. I rely on the concepts of negligence and necropolitics. The first refers to the abdication of authorities in providing sufficient basic services to its citizens. The second - coined by Achille Mbembe before the pandemic - is used to explain the banalization by governments of preventable deaths of discriminated social groups. On a global level, the problematic access to medical equipment and vaccines was a failure because of the hoarding of vaccines by rich nations and the blaming of developing countries for their high mortality. The result was that national and international governmental reactions to COVID-19 worsened health asymmetries within countries and between the Global North and South.

本文重点关注巴西和秘鲁,它们是 2020 年和 2021 年冠状病毒大流行的拉丁美洲中心。疫情放大了这些国家多年来的新自由主义政策、腐败和种族主义、减贫计划的局限性、民主制度的脆弱性,以及政治上对公共卫生和基本卫生设施的不重视。我依据的是 "疏忽 "和 "死亡政治学 "这两个概念。前者是指当局放弃为公民提供足够的基本服务。第二个概念是阿奇尔-姆贝姆贝(Achille Mbembe)在大流行病之前提出的,用来解释政府将受歧视社会群体可预防的死亡平庸化的现象。在全球范围内,由于富裕国家囤积疫苗,并将发展中国家的高死亡率归咎于它们,因此医疗设备和疫苗的获取出现了问题。结果,国家和国际政府对 COVID-19 的反应加剧了国家内部以及全球南北之间的卫生不对称。
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引用次数: 0
The Pandemic Arc: Expanded Narratives in the History of Global Health. 大流行弧线:全球卫生史中的扩展叙事。
IF 0.9 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-09-23 DOI: 10.1093/jhmas/jrae008
Monica H Green

Using the examples of plague, smallpox, and HIV/AIDS, the present essay argues for the benefits of incorporating the evolutionary histories of pathogens, beyond visible epidemic spikes within human populations, into our understanding of what pandemics actually are as epidemiological phenomena. The pandemic arc - which takes the pathogen as the defining "actor" in a pandemic, from emergence to local proliferation to globalization - offers a framework capable of bringing together disparate aspects not only of the manifestations of disease but also of human involvement in the pandemic process. Pathogens may differ, but there are common patterns in disease emergence and proliferation that distinguish those diseases that become pandemic, dispersed through human communities regionally or globally. The same methods of genomic analysis that allow tracking the evolutionary development of a modern pathogen such as SARS-CoV-2 also allow us to trace pandemics into the past. Reconstruction of these pandemic arcs brings new elements of these stories into view, recovering the experiences of regions and populations hitherto overlooked by Eurocentric narratives. This expanded global history of infectious diseases, in turn, lays a groundwork for reconceiving what ambitions a truly global health might aim for.

本文以鼠疫、天花和艾滋病毒/艾滋病为例,论证了将病原体的进化史--除了在人群中可见的流行高峰--纳入我们对流行病学现象的理解中的益处。大流行弧--将病原体作为大流行的决定性 "角色",从出现到局部扩散再到全球化--提供了一个框架,不仅能够将疾病表现的不同方面,而且能够将人类参与大流行过程的不同方面结合起来。病原体可能各不相同,但疾病的出现和扩散有共同的模式,这些模式区分了那些成为大流行病的疾病,这些疾病通过人类社区在地区或全球范围内扩散。通过基因组分析方法,我们可以追踪 SARS-CoV-2 等现代病原体的进化发展,同样也可以追踪过去的大流行。对这些大流行病弧线的重构为这些故事带来了新的元素,恢复了迄今为止被欧洲中心主义叙事所忽视的地区和人群的经历。反过来,这种扩大的全球传染病史也为重新认识真正的全球健康目标奠定了基础。
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引用次数: 0
The End of the Beginning? Temporality and Bioagency in Pandemic Research. 起点的终点?大流行病研究中的时间性与生物代理。
IF 0.9 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-09-23 DOI: 10.1093/jhmas/jrae006
Mandisa Mbali

This paper deals with the ways in which the intellectual and political history of AIDS can assist in the chronological conceptualization of a pandemic such as COVID-19 as it is unfolding. It problematizes the idea of pandemic "beginnings" and "ends" to show that such definitions are shaped by the disciplinary location and thematic foci of relevant scholars. Central to this analysis is the notion that ethical and political contexts affect research on a pandemic in different ways at national and global levels at various points in its trajectory. The article develops this argument in relation to two main themes: firstly, with reference to the history of AIDS research in South Africa; secondly, with the philosophical concept of bioagency to understand the ways in which viruses and humans co-shape the course of epidemics over time. I first make the case for the development of historically informed, long-term ethnographic studies of COVID-19. Using bioagency as a point of departure to consider viruses as social actors, the essay then critiques the notion of bioinformationalism as catalyzing the widening accessibility of biomedical research. Instead, I discuss the biotechnology and pharmaceutical industries as protagonists in the operation of biocapital. I argue that the history of AIDS in South Africa can provide methodological and theoretical insights into how to interpret an unfolding epidemic, outlining an ambitious transdisciplinary research agenda for thinking about the temporality of a pandemic spanning the different, interconnected, scales of life.

本文论述了艾滋病的思想史和政治史如何有助于对 COVID-19 等大流行病按时间顺序进行概念化。本文对大流行病 "开始 "和 "结束 "的概念提出了质疑,以说明此类定义是由相关学者的学科定位和主题焦点所决定的。这一分析的核心概念是:在大流行病发展的不同阶段,伦理和政治背景会以不同的方式影响国家和全球层面的大流行病研究。文章围绕两大主题展开论述:首先,参考南非艾滋病研究的历史;其次,用生物代理的哲学概念来理解病毒和人类共同塑造流行病长期发展过程的方式。我首先提出了对 COVID-19 进行有历史依据的长期人种学研究的理由。文章以生物机构为出发点,将病毒视为社会行动者,然后批判了生物信息主义催化生物医学研究普及化的概念。相反,我讨论了作为生物资本运作主角的生物技术和制药行业。我认为,南非的艾滋病史可以为如何解读正在蔓延的流行病提供方法论和理论上的启示,并概述了一个雄心勃勃的跨学科研究议程,以思考跨越不同、相互关联的生命尺度的流行病的时间性。
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引用次数: 0
Environmental Materialities and the History of Pandemics. 环境物质性与流行病史。
IF 0.9 3区 哲学 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-09-23 DOI: 10.1093/jhmas/jrae007
Emily Webster

Over the last several decades, a growing group of environmental and medical historians have argued that engagement with the materiality of disease is critical to eroding the false boundaries between environment and health, and especially to the historical study of major epidemics and pandemics. This article evaluates the ways in which environmental and medical historians have engaged materiality when thinking through questions of infectious disease. It argues that far from eschewing cultural constructions of disease and analysis of medical systems, these works demonstrate that engagement with materiality in the study of disease articulates the stakes of medical regimes and practices of healing, and renders legible the multiple scales at which epidemics occur. Addressing key controversies in the use of sources, it provides examples of works that incorporate material objects, biological ideas and actors, and non-humans without falling prey to the extremes of "biological determinism" or "constructivism." It argues that commonalities in the methods employed by these works - utilization of scientific frameworks and data, multispecies analysis, attention to scale, and spatial thinking - reveal unseen and untold aspects of past pandemics. It concludes with a brief example of how these frameworks come together in practice through a case study on the history of enteric fever in Dublin, Ireland.

在过去的几十年中,越来越多的环境史和医学史学者认为,参与疾病的物质性对于打破环境与健康之间的虚假界限至关重要,尤其是对于重大流行病和大流行病的历史研究而言。本文评估了环境史和医学史学者在思考传染病问题时参与物质性的方式。文章认为,这些著作不仅没有放弃对疾病的文化建构和对医疗体系的分析,反而证明了在疾病研究中对物质性的参与阐明了医疗制度和治疗实践的利害关系,并使流行病发生的多种规模变得清晰可见。针对资料来源使用方面的主要争议,该书提供了一些作品实例,这些作品将物质对象、生物观念和行为者以及非人类纳入其中,而没有陷入 "生物决定论 "或 "建构主义 "的极端。文章认为,这些作品所采用方法的共性--利用科学框架和数据、多物种分析、关注规模和空间思维--揭示了过去大流行病不为人知的一面。最后,通过对爱尔兰都柏林肠热病历史的案例研究,简要说明了这些框架在实践中是如何结合在一起的。
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引用次数: 0
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Journal of the History of Medicine and Allied Sciences
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