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Derivation of Embedded Diagonally Implicit Methods for Directly Solving Fourth-order ODEs 直接求解四阶 ODE 的嵌入对角线隐含方法的推导
Pub Date : 2024-01-20 DOI: 10.30526/37.1.3288
Omar Mohammed Saleh, Firas A. Fawzi, Kasim Hussain, Nizam G. Ghawadri
EDIRKTO, an Implicit Type Runge-Kutta  Method of Diagonally Embedded pairs, is a novel approach presented in the paper that may be used to solve 4th-order ordinary differential equations of the form . There are two pairs of EDIRKTO, with three stages each: EDIRKTO4(3) and EDIRKTO5(4). The derivation techniques of the method indicate that the higher-order pair is more accurate, while the lower-order pair provides superior error estimates. Next, using these pairs as a basis, we developed variable step codes and applied them to a series of -order ODE problems. The numerical outcomes demonstrated how much more effective their approach is in reducing the quantity of function evaluations needed to resolve fourth-order ODE issues.
EDIRKTO 是一种对角嵌入式隐式 Runge-Kutta 方法,是论文中提出的一种新方法,可用于求解形式为 . 的四阶常微分方程。EDIRKTO 有两对,每对有三个阶段:EDIRKTO4(3) 和 EDIRKTO5(4)。该方法的推导技术表明,高阶对更精确,而低阶对则能提供更优越的误差估计。接下来,我们以这些方法对为基础,开发了可变步长代码,并将其应用于一系列-阶 ODE 问题。数值结果表明,它们能更有效地减少解决四阶 ODE 问题所需的函数求值数量。
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引用次数: 0
Study the Quality of IMRT and VMAT Treatment Planning Techniques (TPS) Using Indices of Achievement (IOA) Nasopharyngeal Cancer Plans 使用成就指数 (IOA) 研究鼻咽癌计划中的 IMRT 和 VMAT 治疗计划技术 (TPS) 的质量
Pub Date : 2024-01-20 DOI: 10.30526/37.1.3277
Ayat Methaq Khalaf, Basim Khalaf Rejah
Volumetric Modulated Arc Therapy (VMAT) and Intensity Modulated Radiation Therapy (IMRT) are comparable for nasopharyngeal cancerous radiation therapy. This research intends to analyze the high-quality plan using accomplishment, conformance, and homogeneity criteria.The study involved 40 patients with a postnasal cancerous tumor. The patients underwent computed tomography (CT) simulation to scan the anatomical details of the patients' heads. Then, their data was forwarded to the treatment planning system (TPS) workstation for IMRT and VMAT planning. The plans were evaluated using the IOA, HI, and CI indices.The nasopharynx coverage results consist of the GTV and PTV at 95%. The statistical study reveals that VMAT provides much more coverage than IMRT for 95% GTV and 95% PTV. The results reveal that VMAT has a substantially better-quality plan (IOA) than IMRT. IMRT provides a superior CI, but VMAT protects the cochlea and optic nerves more effectively. In addition, the IMRT is advantageous for the preservation of additional OARs. There is no statistical difference in protection for the mandible and parotid glands between the two procedures. The VMAT has superior coverage for the gross and planned target volumes and achievement indices. The conformity of IMRT in the tumor target area is better, while VMAT can better protect the cochlea and optic nerves.
体积调制弧线疗法(VMAT)和调强放射疗法(IMRT)在鼻咽癌放射治疗中具有可比性。这项研究旨在利用成就感、一致性和均匀性标准分析高质量计划。研究涉及 40 名鼻咽癌后肿瘤患者。这些患者接受了计算机断层扫描(CT)模拟,以扫描患者头部的解剖细节。然后,他们的数据被传送到治疗计划系统(TPS)工作站,进行 IMRT 和 VMAT 计划。使用 IOA、HI 和 CI 指数对计划进行评估。鼻咽部的覆盖结果包括 95% 的 GTV 和 PTV。统计研究显示,在 95% 的 GTV 和 95% 的 PTV 中,VMAT 的覆盖率远高于 IMRT。结果显示,VMAT 的计划质量(IOA)大大优于 IMRT。IMRT 的 CI 更优,但 VMAT 能更有效地保护耳蜗和视神经。此外,IMRT 在保护额外的 OAR 方面更具优势。两种手术在保护下颌骨和腮腺方面没有统计学差异。VMAT 在总目标量和计划目标量的覆盖范围以及成就指数方面都更胜一筹。IMRT 在肿瘤靶区的一致性更好,而 VMAT 能更好地保护耳蜗和视神经。
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引用次数: 0
Comparison of Complex Sadik and KAJ Transforms for Ordinary Differential Equations to the Response of an Uncompressed Forced Oscillator 常微分方程的复萨迪克变换和 KAJ 变换与非压缩强迫振荡器响应的比较
Pub Date : 2024-01-20 DOI: 10.30526/37.1.3326
Saed M. Turq, Emad A. Kuffi
In this paper we have presented a comparison between two novel integral transformations that are of great importance in the solution of differential equations. These two transformations are the complex Sadik transform and the KAJ transform. An uncompressed forced oscillator, which is an important application, served as the basis for comparison. The application was solved and exact solutions were obtained. Therefore, in this paper, the exact solution was found based on two different integral transforms: the first integral transform complex Sadik and the second integral transform KAJ. And these exact solutions obtained from these two integral transforms were new methods with simple algebraic calculations and applied to different problems. The main purpose of this comparison is the exact solutions, and until we show the importance of the diversity and difference of the kernel of the integral transform by keeping the period t between 0 and infinity.
在本文中,我们比较了在微分方程求解中具有重要意义的两种新型积分变换。这两种变换是复萨迪克变换和 KAJ 变换。比较的基础是一个未压缩的强迫振荡器,这是一个重要的应用。对该应用进行了求解,并获得了精确解。因此,本文根据两种不同的积分变换找到了精确解:第一种是复萨迪克积分变换,第二种是 KAJ 积分变换。从这两种积分变换中得到的精确解是新方法,只需进行简单的代数计算,并适用于不同的问题。这次比较的主要目的是精确解,直到我们通过将周期 t 保持在 0 和无穷大之间来显示积分变换核的多样性和差异性的重要性。
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引用次数: 0
Anti-Oxidant and Anti-Microbial Activities of [ZnO: CoO/ Eugenol] and [ZnO: Fe2O3/ Eugenol] Nanocomposites 氧化锌:CoO/丁香酚]和[氧化锌:Fe2O3/丁香酚]纳米复合材料的抗氧化和抗微生物活性
Pub Date : 2024-01-20 DOI: 10.30526/37.1.3233
Fatin A. Al-jubouri, Basim I. Al-Abdaly
Metal oxide nanocomposites (MONCs) manufacturing is increasingly gaining popularity. The primary cause of this is the broad range of applications for such materials, which include fuel cells, photovoltaics, cosmetics, medicine, semiconductor packing materials, water treatment, and catalysts. Due to their size, stability, high surface area, catalytic activity, simplicity in fabrication, and selectivity for particular reactions. The MONCs with various morphologies have been created by physical, chemical, and biological processes, such as sol-gel, hydrothermal, co-precipitation, solvothermal, and microwave irradiation. Eugenol (4-allyl-2-methoxyphenol) is a major component of clove essential oil and it was found in various plant groups, has been widely utilized, and famously stated to have a variety of important biological activities. It is a good starting material for the synthesis of a wide variety of derivatives with different activity. Due to the presence of many functional groups in its structure, including allyl (-CH2-CH=CH2), phenol (-OH), and methoxy (-OCH3). The eugenol was taken with metal oxides (zinc cobalt oxides ZnO: CoO) to synthesis [ZnO: CoO/ Eug] and (zinc ferric oxides ZnO: Fe2O3) to synthesis [ZnO: Fe2O3/ Eug] as nanocomposites by hydrothermal method and characterization the compounds using: (FT-IR, AFM, SEM, EDX, XRD) techniques. Then, they tested their biological activities through antimicrobial and antioxidant.
金属氧化物纳米复合材料(MONCs)的生产越来越受欢迎。其主要原因是此类材料应用广泛,包括燃料电池、光伏、化妆品、医药、半导体填料、水处理和催化剂。由于其尺寸小、稳定性好、比表面积高、催化活性强、制造简单以及对特定反应具有选择性,因此被广泛应用于燃料电池、光伏、化妆品、医药、半导体包装材料、水处理和催化剂等领域。通过溶胶-凝胶、水热、共沉淀、溶热和微波辐照等物理、化学和生物工艺,可以制造出具有各种形态的 MONCs。丁香酚(4-烯丙基-2-甲氧基苯酚)是丁香精油的主要成分,它存在于多种植物类群中,被广泛利用,具有多种重要的生物活性。它是合成各种具有不同活性的衍生物的良好起始原料。由于丁香酚的结构中存在许多官能团,包括烯丙基(-CH2-CH=CH2)、苯酚(-OH)和甲氧基(-OCH3)。通过水热法将丁香酚与金属氧化物(锌钴氧化物 ZnO:CoO)合成[ZnO:CoO/ Eug]和(锌铁氧化物 ZnO:Fe2O3)合成[ZnO:Fe2O3/ Eug]纳米复合材料,并使用傅立叶变换红外光谱(FT-IR)、原子力显微镜(AFM)、扫描电镜(SEM)、电子显微镜(EDX)、X射线衍射(XRD)等技术对化合物进行表征。然后,他们通过抗菌和抗氧化测试了这些化合物的生物活性。
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引用次数: 1
Synthesis and Study Medical Application of Nanocomposites Based on grafted Chitosan /Polyvinyl alcohol 基于接枝壳聚糖/聚乙烯醇的纳米复合材料的合成与医学应用研究
Pub Date : 2024-01-20 DOI: 10.30526/37.1.3327
Ruwaidah S.Saeed, Widad Abed Shlaka, El-Sayed Negim
In the present study, synthesis of bis Schiff base [I, II] by reaction of one mole of terephthalaldehyde with two mole of 2-amino-5-mercapto-1,3,4-thiadiazole or 4-amino benzene thiol in the ethanol absolute, then compounds [I,II]  were reacted with Na2CO3 of distilled H2O, then chloroacetic acid was added to yield compounds [III,IV]. O-chitosan derivatives [V,VI] were synthesized by reaction of chitosan with compounds [III,IV] in acidic media in distilled water according to the steps of Fischer. O–chitosan (grafted chitosan) [V,VI] was blended with synthetic polymer polyvinyl alcohol (PVA) to produce polymers [VII,VIII], then these polymers were blended with nano: Gold or Silver by using a hotplate stirrer for 3 hours to produce nanocomposites [IX- XII]. The synthesized polymers were identified using spectral analysis techniques, including FTIR,1H-NMR, and scanning electron microscope (SEM). Molecular docking was studied, where operations are used to predict the binding status of compounds with the enzyme and to calculate the free energy (ΔG) of the prepared compounds. Finally, the study of biological activities was screened via two types of bacteria. Also, the anti-cancer activity against human lung adenocarcinoma cells (A549) was studied and compared with standard cell line [REF(R7540) Rat Embryonic Fibroblasts] of some of the blended polymers and nanocomposites, then the acute toxicity test of some nanocomposites was performed.
在本研究中,通过将一摩尔对苯二甲醛与两摩尔 2-氨基-5-巯基-1,3,4-噻二唑或 4-氨基苯硫醇在绝对乙醇中反应合成双席夫碱[I,II],然后将化合物[I,II]与蒸馏水中的 Na2CO3 反应,再加入氯乙酸生成化合物[III,IV]。按照费舍尔的步骤,壳聚糖与化合物[III,IV]在蒸馏水中的酸性介质中反应,合成 O 型壳聚糖衍生物[V,VI]。将 O 型壳聚糖(接枝壳聚糖)[V,VI]与合成聚合物聚乙烯醇(PVA)混合,制得聚合物[VII,VIII],然后使用热板搅拌器将这些聚合物与纳米金或银混合 3 小时,制得纳米复合材料[IX- XII]。利用傅立叶变换红外光谱、1H-核磁共振和扫描电子显微镜(SEM)等光谱分析技术对合成的聚合物进行鉴定。分子对接研究用于预测化合物与酶的结合状态,并计算所制备化合物的自由能(ΔG)。最后,通过两种细菌进行了生物活性研究。此外,还研究了一些共混聚合物和纳米复合材料对人类肺腺癌细胞(A549)的抗癌活性,并与标准细胞系[REF(R7540) 大鼠胚胎成纤维细胞]进行了比较,然后对一些纳米复合材料进行了急性毒性测试。
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引用次数: 0
On The Double Integral Transform (Complex EE Transform) and Their Properties and Applications 论双积分变换(复 EE 变换)及其性质和应用
Pub Date : 2024-01-20 DOI: 10.30526/37.1.3329
Ahmad Issa, Emad Kuffi
Due to the importance of solutions of partial differential equations, linear, nonlinear, homogeneous, and non-homogeneous, in important life applications, including engineering applications, physics and astronomy, medical sciences, and life technology, and their importance in solutions to heat transfer equations, wave, Laplace equation, telegraph, etc. In this paper, a new double integral transform has been proposed.In this work, we have introduced a new double transform ( Double Complex EE Transform ). In addition, we presented the convolution theorem and proved the properties of the proposed transform, which has an effective and useful role in dealing with the solution of two-dimensional partial differential equations. Moreover, two examples of important mathematical equations are solved to illustrate method. This double  integral transformation has a complex kernel.
由于偏微分方程(线性、非线性、均质和非均质)的解在工程应用、物理和天文学、医学科学和生命技术等重要生活应用中的重要性,以及它们在传热方程、波、拉普拉斯方程、电报等解中的重要性。在本文中,我们提出了一种新的双积分变换(Double Complex EE Transform)。此外,我们还提出了卷积定理,并证明了所提变换的性质,该变换在处理二维偏微分方程的求解方面具有有效和实用的作用。此外,我们还解决了两个重要数学方程的例子来说明方法。这种双积分变换具有复核。
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引用次数: 0
An Assessment of Glutathione-S-Transferase and Lipid Profile in Obese Iraqi Patients 评估伊拉克肥胖症患者的谷胱甘肽-S-转移酶和血脂概况
Pub Date : 2024-01-20 DOI: 10.30526/37.1.3252
Nabaa Adnan Mohammed, Fayhaa Muqdad Khaleel
Obesity is a chronic disease that may have genetic, environmental, and other causes. Obesity is a shortcut to many diseases, such as hypertension, diabetes, atherosclerosis, and other chronic diseases. Oxidative stress increases obesity through free radicals. Glutathione S-transferase (GST) is a metabolic enzyme used to remove toxins. This study aimed to determine GST activity in obese patients as a predictor of oxidative stress and the effectiveness of lipid profiling in obese patients. The study included 139 samples of obese and healthy people (obese group 84 and healthy group 55). Both groups (obese and healthy groups) were divided into four groups based on body mass index. Blood samples were collected from obese males and females in Al-Yarmouk Hospital. Some biochemical parameters were measured for all study groups, including estimation of lipid profile, FSG, and GST activity. Results have shown a significant increase in low-density lipoprotein cholesterol (LDL-C) in obese groups and showed a rise in GST levels in healthy groups compared with obese groups (p < 0.05). These studies show that being overweight or obese makes you more likely to get heart disease and other illnesses. It has been demonstrated that the slightly lower levels of GST in the overweight and obese groups compared to other groups demonstrate the precise role of GST in its decrease with weight gain, along with an increase in LDL-C level.
肥胖症是一种慢性疾病,可能有遗传、环境和其他原因。肥胖是导致高血压、糖尿病、动脉粥样硬化等多种疾病的捷径。氧化应激通过自由基增加肥胖。谷胱甘肽 S 转移酶(GST)是一种用于清除毒素的代谢酶。本研究旨在确定肥胖患者体内作为氧化应激预测因子的 GST 活性以及肥胖患者脂质分析的有效性。研究包括 139 份肥胖者和健康者样本(肥胖组 84 份,健康组 55 份)。两组(肥胖组和健康组)均按体重指数分为四组。在 Al-Yarmouk 医院采集了肥胖男性和女性的血液样本。对所有研究组的一些生化参数进行了测量,包括估计血脂概况、FSG 和 GST 活性。结果显示,与肥胖组相比,肥胖组的低密度脂蛋白胆固醇(LDL-C)明显增加,健康组的 GST 水平也有所上升(P < 0.05)。这些研究表明,超重或肥胖更容易患心脏病和其他疾病。研究表明,与其他组别相比,超重和肥胖组的 GST 水平略低,这说明 GST 在体重增加、低密度脂蛋白胆固醇水平升高的同时,其作用也在降低。
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引用次数: 0
Assessment of Monocyte Chemoattractant Protein -1 and Fertility Hormones in Iraqi Women with Polycystic Ovarian Syndrome 伊拉克多囊卵巢综合症妇女体内单核细胞趋化蛋白-1 和生育激素的评估
Pub Date : 2024-01-20 DOI: 10.30526/37.1.3307
S. K. Ibrahim, Sura Fouad Alsaffar
Polycystic ovarian syndrome (PCOS) is a well-known endocrinopathy and one of the most frequent endocrine-reproductive-metabolic syndromes in women, which can result in reduced fertility. While the actual cause is unknown, PCOS is regarded as a complicated genetic characteristic with a great degree of variability. Moreover, hormones and immune cells, including both innate and acquired immune cells, are thought to interact in PCOS. Chronic low-grade inflammation raises the risk of autoimmune disease. The study's purpose is to investigate the chemokine monocyte chemoattractant protein-1 (MCP-1) and fertility hormones in samples of women patients with polycystic ovary syndrome (PCOS) in the City of Medicine. Sixty PCOS women comprise 30 healthy control women; their average age was 20–40 years, and their weight ranged from 60 to 100 kg. The results showed an increase in the level of MCP1 in PCOS patients, but this increase was not significant (P<0.05), which was not influenced by BMI or fertility hormones. As well as elevated fertility hormones, this study, when compared to controls as well as patients with PCOS, showed a significant increase in the level of testosterone (14.63 ±2.30 nmol/L) while in control women (0.627 ±0.04), LH hormone in patients and control group (6.54 ±0.51 mIU/mL), and 2.93 ±0.18, respectively. Prolactin hormone was increased in PCOS patients (16.27 ±1.25 ng/mL) when compared to the control group (12.85 ±0.62). There was no significant difference in FSH hormone in women with PCOS (5.27 ±0.28 mIU/mL) compared with the control group (5.59 ±0.18).
多囊卵巢综合征(PCOS)是一种众所周知的内分泌疾病,也是女性最常见的内分泌-生殖-代谢综合征之一,可导致生育能力下降。多囊卵巢综合征的真正病因尚不清楚,但被认为是一种复杂的遗传特征,具有很大的变异性。此外,激素和免疫细胞(包括先天性免疫细胞和获得性免疫细胞)被认为在多囊卵巢综合征中相互作用。慢性低度炎症会增加患自身免疫性疾病的风险。这项研究的目的是调查医学城多囊卵巢综合症(PCOS)女性患者样本中的趋化因子单核细胞趋化蛋白-1(MCP-1)和生育激素。60 名多囊卵巢综合征妇女和 30 名健康对照组妇女;她们的平均年龄为 20-40 岁,体重从 60 公斤到 100 公斤不等。结果显示,多囊卵巢综合征患者的 MCP1 水平有所上升,但上升幅度不大(P<0.05),且不受体重指数或生育激素的影响。在生育激素升高方面,与对照组和多囊卵巢综合征患者相比,本研究显示睾酮水平(14.63 ±2.30 nmol/L)显著升高,而对照组妇女的睾酮水平(0.627 ±0.04)、患者和对照组的 LH 激素水平(6.54 ±0.51 mIU/mL)和 LH 激素水平(2.93 ±0.18)分别显著升高。与对照组(12.85 ±0.62)相比,多囊卵巢综合症患者的催乳激素(16.27 ±1.25 ng/mL)有所增加。与对照组(5.59 ±0.18)相比,多囊卵巢综合征妇女的 FSH 激素(5.27 ±0.28 mIU/mL)无明显差异。
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引用次数: 0
A Review using continuous flow injection analysis technique in the determination of several drugs 利用连续流动注射分析技术测定多种药物的综述
Pub Date : 2024-01-20 DOI: 10.30526/37.1.3182
Elham N. Mezaal, Kawther Ahmed Sadiq, Tamara Ahmed Abdel Karim
Continuous flow injection analysis (CFIA) is one of the simplest, easiest, and multilateral analytical automation methods in moist chemical analysis. This method depends on changing the physical and chemical properties of a part of the specimen spread out from the specimen injected into the carrier stream. The CFIA technique uses automatic analysis of samples with high efficiency. The CFIA PC compatibility also allows specimens to be treated automatically, reagents to be added, and reaction conditions to be closely monitored. The CFIA is one of the automated chemical analysis methods in which a successive specimen sample is to be estimated and injected into a vector stream from a flowing solution that meets the reagent and mixes at a specific point, the y-junction, before reaching the detector. However, CFIA does not have a separation method because the sample, carrier stream, and reagent all enter the system simultaneously and move together at a specific flow rate to the end of the system. It is also possible to inject a second specimen sample to be estimated before the first sample reaches the detector. For all the reasons mentioned, the CFIA technique analysis is appropriate, fast, and ideal for analyzing different samples. This general technique deals with solutions and is used for various tasks, including pH measurement, conductivity, colorimetry, titration, and enzyme assays. So, it was used in analytical chemistry to estimate many samples, including medicines, because they are essential substances for human life, and everyone widely uses them.
连续流动注射分析法(CFIA)是湿化学分析中最简单、易用和多用途的自动化分析方法之一。这种方法依赖于改变从注入载流的试样中扩散出来的部分试样的物理和化学性质。CFIA 技术可高效地自动分析样品。CFIA PC 兼容性还允许自动处理标本、添加试剂和密切监控反应条件。CFIA 是自动化学分析方法之一,在这种方法中,连续的标本样品需要估算,并从流动的溶液中注入矢量流,在到达检测器之前,溶液与试剂在一个特定的点,即 y 交界处混合。然而,CFIA 没有分离方法,因为样本、载体流和试剂都同时进入系统,并以特定的流速一起移动到系统的末端。在第一个样品到达检测器之前,还可以注入第二个样品样本进行估计。基于上述原因,CFIA 技术分析适用、快速,是分析不同样品的理想选择。这种通用技术处理溶液,可用于各种任务,包括 pH 值测量、电导率、比色法、滴定和酶测定。因此,它被用于分析化学中对包括药品在内的许多样品进行评估,因为药品是人类生活中不可或缺的物质,每个人都在广泛使用它们。
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引用次数: 0
The Efficacy of Feed Restriction Program on Broiler Production: A Review 饲料限制计划对肉鸡生产的功效:综述
Pub Date : 2024-01-20 DOI: 10.30526/37.1.3282
Hamdeen Yahia Dawood
Poultry often intake energy to meet their energy needs, which is associated with both more fat and protein deposition, which is also conditioned by the presence of adequate other nutritional nutrients. The most significant supplement in creature sustenance or diets is protein, with exceptional thought given to the proportion among energy and protein in consumes less calories (energy: protein ratio EPR). This implies that a specific protein level relates with the fundamental measure of energy in the eating regimen. The article evaluated the manipulation of energy to protein ratio and its effect on broiler performance and carcass lipid profile. The author's methodology depends on analyzing and comparing other scientists’ studies and work to evaluate the impact of protein-to-energy ratio on broiler performance and carcass fat deposition and found that high-energy or high-protein diets and widening the energy-to-protein ratio significantly increased fat deposition. Also, a low-energy diet increased broiler total cholesterol.
家禽经常摄入能量以满足其能量需求,这与脂肪和蛋白质沉积较多有关,也受其他营养成分充足与否的制约。蛋白质是生物饲料或日粮中最重要的补充营养素,特别要考虑能量和蛋白质在消耗较少热量中的比例(能量:蛋白质比率 EPR)。这意味着特定的蛋白质水平与膳食中能量的基本比例有关。这篇文章评估了能量与蛋白质比率的调节及其对肉鸡生产性能和胴体脂质特征的影响。作者的研究方法依赖于分析和比较其他科学家的研究和工作,以评估蛋白质-能量比对肉鸡生产性能和胴体脂肪沉积的影响,结果发现,高能量或高蛋白日粮以及扩大能量-蛋白质比会显著增加脂肪沉积。此外,低能量日粮还会增加肉鸡的总胆固醇。
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引用次数: 0
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Ibn AL-Haitham Journal For Pure and Applied Sciences
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